The network for 'neuroblast proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

neuroblast proliferation

The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.

NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog0.999
Fgf8fibroblast growth factor 80.998
Emx1empty spiracles homolog 1 (Drosophila)0.997
Ctnnb1catenin (cadherin associated protein), beta 10.996
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.994
Otx2orthodenticle homolog 2 (Drosophila)0.994
Pax2paired box gene 20.994
Sox2SRY-box containing gene 20.992
Isl1ISL1 transcription factor, LIM/homeodomain0.990
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.989
Pax6paired box gene 60.989
Pax3paired box gene 30.984
Fgfr2fibroblast growth factor receptor 20.979
Hes1hairy and enhancer of split 1 (Drosophila)0.970
Foxc1forkhead box C10.962
Bmp4bone morphogenetic protein 40.954
Gli3GLI-Kruppel family member GLI30.945
Ntf3neurotrophin 30.940
Ptenphosphatase and tensin homolog0.927
Rargretinoic acid receptor, gamma0.925
Lhx3LIM homeobox protein 30.918
Emx2empty spiracles homolog 2 (Drosophila)0.912
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.906
Wnt3awingless-related MMTV integration site 3A0.899
Pitx2paired-like homeodomain transcription factor 20.894
Hoxd11homeobox D110.886
Pou3f3POU domain, class 3, transcription factor 30.850
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.847
Wnt5awingless-related MMTV integration site 5A0.844
Tbx3T-box 30.835
Snai1snail homolog 1 (Drosophila)0.828
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.776
Twist2twist homolog 2 (Drosophila)0.771
Vegfavascular endothelial growth factor A0.770
Eya1eyes absent 1 homolog (Drosophila)0.758
Gli2GLI-Kruppel family member GLI20.758
Arid1aAT rich interactive domain 1A (SWI-like)0.758
Jag1jagged 10.757
Otx1orthodenticle homolog 1 (Drosophila)0.756
Tcfap2atranscription factor AP-2, alpha0.752
Efnb2ephrin B20.739
Lef1lymphoid enhancer binding factor 10.727
Msx2homeobox, msh-like 20.723
Myod1myogenic differentiation 10.708
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.702
Rb1retinoblastoma 10.693
Hoxd13homeobox D130.677
En1engrailed 10.670
Neurog1neurogenin 10.654
Fgf10fibroblast growth factor 100.648
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.648
Lhx5LIM homeobox protein 50.647
Foxa2forkhead box A20.631
Bdnfbrain derived neurotrophic factor0.624
Lhx1LIM homeobox protein 10.605
Onecut1one cut domain, family member 10.594
Hoxa1homeobox A10.593
Pou3f2POU domain, class 3, transcription factor 20.588
Hoxa10homeobox A100.583
Sim1single-minded homolog 1 (Drosophila)0.577
Hoxa13homeobox A130.562
Fzd8frizzled homolog 8 (Drosophila)0.559
Neurod1neurogenic differentiation 10.554
Efnb1ephrin B10.553
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.553
Ascl1achaete-scute complex homolog 1 (Drosophila)0.550
Rararetinoic acid receptor, alpha0.543
Smad6MAD homolog 6 (Drosophila)0.537
Vhlvon Hippel-Lindau tumor suppressor0.535
Acvr1activin A receptor, type 10.526
Fgf3fibroblast growth factor 30.523
Ephb2Eph receptor B20.518
Fgfr1fibroblast growth factor receptor 10.510
Id3inhibitor of DNA binding 30.484
Neurog2neurogenin 20.483
Ror1receptor tyrosine kinase-like orphan receptor 10.467
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.465
Pax8paired box gene 80.461
Foxg1forkhead box G10.461
Fzd1frizzled homolog 1 (Drosophila)0.459
Id1inhibitor of DNA binding 10.438
Sox11SRY-box containing gene 110.432
Lmx1bLIM homeobox transcription factor 1 beta0.430
Gbx2gastrulation brain homeobox 20.429
Smosmoothened homolog (Drosophila)0.424
Gata4GATA binding protein 40.418
Vax1ventral anterior homeobox containing gene 10.417
Meox2mesenchyme homeobox 20.409
Dkk1dickkopf homolog 1 (Xenopus laevis)0.407
Tbx2T-box 20.406
Hand2heart and neural crest derivatives expressed transcript 20.404
Sox4SRY-box containing gene 40.394
Hif3ahypoxia inducible factor 3, alpha subunit0.390
Tbx1T-box 10.386
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.382
Retret proto-oncogene0.375
Neurog3neurogenin 30.359
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.353
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-30Protein EGL-300.220
goa-1Protein GOA-10.179
sas-4Protein SAS-40.142
pha-4Protein PHA-40.127
F29B9.11Protein F29B9.110.115
tpxl-1Protein TPXL-10.105
egl-18Protein EGL-180.101
pde-4Protein PDE-40.091
lag-1Protein LAG-10.075
gon-2Protein GON-20.070
T09B4.5Protein T09B4.50.068
par-1Protein PAR-10.064
sun-1Protein SUN-10.063
let-60Protein LET-600.054
pig-1Protein PIG-10.049
pry-1Protein PRY-10.049
ztf-2Protein ZTF-20.045
mes-4Protein MES-40.043
sys-1Protein SYS-10.043
nhr-67Protein NHR-670.039
CELE_R11H6.2Protein R11H6.20.038
air-2Protein AIR-20.037
dcap-2Protein DCAP-20.036
wht-7Protein WHT-70.034
cul-2Protein CUL-20.029
mys-1Protein MYS-10.028
csnk-1Protein CSNK-10.027
gpb-1Protein GPB-10.026
grd-1Protein GRD-10.026
Y59E9AL.4Protein Y59E9AL.40.026
zyg-11Protein ZYG-110.025
sox-2Protein SOX-20.025
F23H11.5Protein F23H11.50.024
bar-1Protein BAR-10.022
rbc-1Protein RBC-10.021
erfa-3Protein ERFA-30.021
fem-1Protein FEM-10.019
cam-1Protein CAM-10.019
pptr-2Protein PPTR-20.019
ten-1Protein TEN-10.019
cnd-1Protein CND-10.018
K10C3.4Protein K10C3.40.018
ets-4Protein ETS-40.018
daf-12Protein DAF-120.018
tbg-1Protein TBG-10.018
tbb-4Protein TBB-40.017
fmi-1Protein FMI-10.017
ced-4Protein CED-40.017
T10B10.8Protein T10B10.80.017
F39B2.1Protein F39B2.10.017
kin-19Protein KIN-190.017
gex-3Protein GEX-30.016
R10E12.2Protein R10E12.20.016
CELE_E01G4.6Protein E01G4.60.015
nhr-6Protein NHR-60.015
dhhc-1Protein DHHC-10.015
zyg-9Protein ZYG-90.015
sdz-28Protein SDZ-280.015
sem-5Protein SEM-50.015
eri-1Protein ERI-10.014
egl-46Protein EGL-460.014
unc-130Protein UNC-1300.014
gpr-1Protein GPR-10.014
CELE_F59A6.5Protein F59A6.50.014
eya-1Protein EYA-10.014
zip-7Protein ZIP-70.014
Y102A11A.6Protein Y102A11A.60.014
tag-260Protein TAG-2600.014
rab-11.1Protein RAB-11.10.014
F13B6.1Protein F13B6.10.014
lsy-2Protein LSY-20.013
elt-6Protein ELT-60.013
sel-10Protein SEL-100.013
zyg-8Protein ZYG-80.013
DH11.5Protein DH11.50.013
mel-11Protein MEL-110.013
afd-1Protein AFD-10.013
T23G4.3Protein T23G4.30.013
pop-1Protein POP-10.013
sam-10Protein SAM-100.013
T23F11.1Protein T23F11.10.013
B0464.6Protein B0464.60.012
xpo-1Protein XPO-10.012
ppk-2Protein PPK-20.012
inx-3Protein INX-30.012
tax-6Protein TAX-60.012
F36D4.5Protein F36D4.50.012
imb-2Protein IMB-20.012
clk-2Protein CLK-20.012
hlh-2Protein HLH-20.011
flh-1Protein FLH-10.011
cyk-7Protein CYK-70.011
C44B7.2Protein C44B7.20.011
col-110Protein COL-1100.011
Y7A9D.1Protein Y7A9D.10.011
F36A2.7Protein F36A2.70.011
CELE_F53H1.3Protein F53H1.30.011
hnd-1Protein HND-10.011
Y45G5AM.9Protein Y45G5AM.90.011
mcd-1Protein MCD-10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ascl1aachaete-scute complex-like 1a (Drosophila)0.970
cdh2cadherin 2, neuronal0.954
fgf3fibroblast growth factor 30.879
lef1lymphocyte enhancer binding factor 10.860
igfbp3insulin-like growth factor binding protein 30.839
ilkintegrin linked kinase0.839
her6hairy-related 60.813
rargaretinoic acid receptor gamma a0.810
gro1groucho 10.686
sox11bSRY-box containing gene 11b0.676
notch1anotch homolog 1a0.664
hey1hairy/enhancer-of-split related with YRPW motif 10.616
zic1zic family member 1 (odd-paired homolog, Drosophila)0.602
cdh1cadherin 1, epithelial0.596
smosmoothened homolog (Drosophila)0.595
emx3empty spiracles homeobox 30.590
notch3notch homolog 30.570
ephb4beph receptor B4b0.559
her8ahairy-related 8a0.543
neurodneurogenic differentiation0.518
foxn4forkhead box N40.497
wnt1wingless-type MMTV integration site family, member 10.496
trpv4transient receptor potential cation channel, subfamily V, member 40.491
pea3ETS-domain transcription factor pea30.470
traf4atnf receptor-associated factor 4a0.464
fgf8afibroblast growth factor 8 a0.457
gli1GLI-Kruppel family member 10.454
her11hairy-related 110.431
spry2sprouty homolog 20.428
sulf1sulfatase 10.428
wlswntless homolog (Drosophila)0.425
neurog1neurogenin 10.415
axin2axin 2 (conductin, axil)0.413
msgn1mesogenin 10.409
pax6bpaired box gene 6b0.398
dkk1bdickkopf 1b0.393
eya1eyes absent homolog 10.386
sox1aSRY-box containing gene 1a0.382
lhx2bLIM homeobox 2b0.380
calb2bcalbindin 2b, (calretinin)0.367
fzd7bfrizzled homolog 7b0.359
pvrl1apoliovirus receptor-related 1a0.358
bocbrother of CDO0.356
alcambactivated leukocyte cell adhesion molecule b0.353
her15.1hairy and enhancer of split-related 15.10.349
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.348
chd7chromodomain helicase DNA binding protein 70.344
krt8keratin 80.343
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.337
ntn1bnetrin 1b0.336
nrarpanotch-regulated ankyrin repeat protein a0.327
dag1dystroglycan 10.325
otx2orthodenticle homolog 20.319
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.317
sox3SRY-box containing gene 30.315
wnt11wingless-type MMTV integration site family, member 110.313
phox2apaired-like homeobox 2a0.307
otpborthopedia homolog b0.304
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.298
opn1sw1opsin 1 (cone pigments), short-wave-sensitive 10.298
prickle2prickle-like 2 (Drosophila)0.298
fgfr1afibroblast growth factor receptor 1a0.288
irx3airoquois homeobox protein 3a0.287
ryr3ryanodine receptor 30.287
pitx3paired-like homeodomain transcription factor 30.286
stau1staufen, RNA binding protein, homolog 1 (Drosophila)0.286
fzd7afrizzled homolog 7a0.284
sox2SRY-box containing gene 20.283
cdh6cadherin 60.282
hfe2hemochromatosis type 20.274
cxcr4bchemokine (C-X-C motif), receptor 4b0.272
sox19aSRY-box containing gene 19a0.271
gng12aguanine nucleotide binding protein (G protein), gamma 12a0.262
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.261
lama1laminin, alpha 10.255
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.252
dtngdystrobrevin, gamma and dystrobrevin, gamma-like0.247
six3asine oculis homeobox homolog 3a0.243
bhlhe22basic helix-loop-helix family, member e220.238
nusap1nucleolar and spindle associated protein 10.236
lfnglunatic fringe homolog0.235
eya4eyes absent homolog 4 (Drosophila)0.233
her1hairy-related 10.232
spry4sprouty (Drosophila) homolog 40.228
otx1borthodenticle homolog 1b0.227
dnmt7DNA (cytosine-5-)-methyltransferase 70.225
appl2adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 20.225
stau2staufen, RNA binding protein, homolog 2 (Drosophila)0.221
dmbx1adiencephalon/mesencephalon homeobox 1a0.215
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.206
ptpraprotein tyrosine phosphatase, receptor type, A0.204
pou1f1POU domain, class 1, transcription factor 10.200
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
bratbrain tumor0.994
E(spl)Enhancer of split0.974
HLHm7E(spl) region transcript m70.972
MED11Mediator complex subunit 110.960
Ggamma1G protein gamma 10.929
ctpcut up0.910
poloCG12306 gene product from transcript CG12306-RA0.869
fz2frizzled 20.862
HLHmgammaE(spl) region transcript mgamma0.856
SAKSak kinase0.844
HLHmbetaE(spl) region transcript mbeta0.797
MadMothers against dpp0.785
G-oalpha47AG protein oalpha 47A0.785
Dhc64CDynein heavy chain 64C0.775
MED4Mediator complex subunit 40.769
MED27Mediator complex subunit 270.760
drkdownstream of receptor kinase0.721
Rca1Regulator of cyclin A10.712
Bj1Bj1 protein0.695
gcmglial cells missing0.675
emcextra macrochaetae0.650
G-ialpha65AG protein alphai subunit 65A0.643
Sas-4CG10061 gene product from transcript CG10061-RA0.626
Rab5Rab-protein 50.622
par-1CG8201 gene product from transcript CG8201-RA0.620
Akt1CG4006 gene product from transcript CG4006-RA0.572
MED9Mediator complex subunit 90.560
chbchromosome bows0.530
InRInsulin-like receptor0.509
HLHm5E(spl) region transcript m50.485
MED6Mediator complex subunit 60.485
rheaCG6831 gene product from transcript CG6831-RA0.475
numbCG3779 gene product from transcript CG3779-RB0.463
osaCG7467 gene product from transcript CG7467-RD0.459
Ras85DRas oncogene at 85D0.458
Pk61CProtein kinase 61C0.444
Stat92ESignal-transducer and activator of transcription protein at 92E0.406
RipalphaRPA-interacting protein alpha0.386
CaMKIICalcium/calmodulin-dependent protein kinase II0.384
HLHmdeltaE(spl) region transcript mdelta0.384
MED31Mediator complex subunit 310.366
CG5690CG5690 gene product from transcript CG5690-RA0.344
CycACyclin A0.341
l(2)gllethal (2) giant larvae0.327
WASpCG1520 gene product from transcript CG1520-RA0.316
mit(1)15mitotic 150.311
sas-6spindle assembly abnormal 60.309
CkIalphaCasein kinase Ialpha0.307
CG1024CG1024 gene product from transcript CG1024-RB0.302
m2E(spl) region transcript m20.299
malphaE(spl) region transcript malpha0.297
Su(H)Suppressor of Hairless0.293
Snr1Snf5-related 10.290
Sas10CG4202 gene product from transcript CG4202-RA0.273
CtBPC-terminal Binding Protein0.272
TomTwin of m40.270
DadDaughters against dpp0.258
pAbppolyA-binding protein0.248
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
PRKCZprotein kinase C, zeta1.000
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.997
CCT8chaperonin containing TCP1, subunit 8 (theta)0.996
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.995
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.993
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.983
MAPTmicrotubule-associated protein tau0.981
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.978
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.968
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.967
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.964
STK11serine/threonine kinase 110.961
PAX3paired box 30.946
CSH1chorionic somatomammotropin hormone 1 (placental lactogen)0.934
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.934
ARID1BAT rich interactive domain 1B (SWI1-like)0.929
NRP1neuropilin 10.917
SMAD2SMAD family member 20.917
CDK2cyclin-dependent kinase 20.912
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.909
MOBKL3MOB1, Mps One Binder kinase activator-like 3 (yeast)0.899
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.871
ETFAelectron-transfer-flavoprotein, alpha polypeptide0.860
MED10mediator complex subunit 100.859
CREBBPCREB binding protein0.858
STILSCL/TAL1 interrupting locus0.852
ZMYND11zinc finger, MYND-type containing 110.840
ZBED1zinc finger, BED-type containing 10.794
APCadenomatous polyposis coli0.792
ARHGAP1Rho GTPase activating protein 10.783
POU3F2POU class 3 homeobox 20.775
TCP1t-complex 10.772
PRKCIprotein kinase C, iota0.758
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.741
JUBjub, ajuba homolog (Xenopus laevis)0.712
TP53tumor protein p530.705
JAG1jagged 10.698
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.685
GH1growth hormone 10.678
FGFR1fibroblast growth factor receptor 10.674
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.663
CCT4chaperonin containing TCP1, subunit 4 (delta)0.629
SNW1SNW domain containing 10.626
TCF4transcription factor 40.618
KIF23kinesin family member 230.608
ARID1AAT rich interactive domain 1A (SWI-like)0.606
GSK3Bglycogen synthase kinase 3 beta0.599
CSHL1chorionic somatomammotropin hormone-like 10.562
HIST1H3Bhistone cluster 1, H3b0.549
CENPFcentromere protein F, 350/400kDa (mitosin)0.545
IGF1Rinsulin-like growth factor 1 receptor0.543
SOS1son of sevenless homolog 1 (Drosophila)0.543
TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 20.532
RHOAras homolog gene family, member A0.529
PLCG1phospholipase C, gamma 10.514
JUPjunction plakoglobin0.508
CCNB1cyclin B10.505
POU5F1POU class 5 homeobox 10.504
LLGL1lethal giant larvae homolog 1 (Drosophila)0.468
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.464
MED6mediator complex subunit 60.445
NR4A1nuclear receptor subfamily 4, group A, member 10.437
CDK1cyclin-dependent kinase 10.433
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.428
ADORA2Aadenosine A2a receptor0.418
PKP2plakophilin 20.404
CSH2chorionic somatomammotropin hormone 20.401
PBRM1polybromo 10.374
FGF10fibroblast growth factor 100.374
PGFplacental growth factor0.370
MAP3K3mitogen-activated protein kinase kinase kinase 30.369
RAD21RAD21 homolog (S. pombe)0.356
APPamyloid beta (A4) precursor protein0.352
CYFIP1cytoplasmic FMR1 interacting protein 10.348
SKIv-ski sarcoma viral oncogene homolog (avian)0.343
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.336
NCOR1nuclear receptor corepressor 10.332
CCNB2cyclin B20.329
TOP2Atopoisomerase (DNA) II alpha 170kDa0.328
CYFIP2cytoplasmic FMR1 interacting protein 20.327
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.327
NCOA6nuclear receptor coactivator 60.324
EPS15epidermal growth factor receptor pathway substrate 150.317
CDK8cyclin-dependent kinase 80.314
NUMA1nuclear mitotic apparatus protein 10.310
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.302
EP300E1A binding protein p3000.300
RBFOX1RNA binding protein, fox-1 homolog (C. elegans) 10.300
PSEN1presenilin 10.298
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.294
ARandrogen receptor0.291
STRADASTE20-related kinase adaptor alpha0.284
CAPNS1calpain, small subunit 10.283
NAP1L1nucleosome assembly protein 1-like 10.280
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.279
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.278
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.278
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.277
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism