The network for 'nonribosomal peptide biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nonribosomal peptide biosynthetic process

The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.

NameDescriptionProbabilityFunc Analog Organism
Sept1septin 10.100
Ndufa6NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (B14)0.098
Zfp335zinc finger protein 3350.080
Cyb5cytochrome b-50.065
Acsl1acyl-CoA synthetase long-chain family member 10.063
Pnpopyridoxine 5'-phosphate oxidase0.055
Fbxo9f-box protein 90.050
Gykglycerol kinase0.049
Gsrglutathione reductase0.045
Fbp2fructose bisphosphatase 20.039
Creg1cellular repressor of E1A-stimulated genes 10.039
Phlda2pleckstrin homology-like domain, family A, member 20.037
Alas1aminolevulinic acid synthase 10.035
Prg2proteoglycan 2, bone marrow0.035
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.034
Pkp3plakophilin 30.032
Ubxn4UBX domain protein 40.031
Il1r2interleukin 1 receptor, type II0.030
Slc19a2solute carrier family 19 (thiamine transporter), member 20.029
Sirt3sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae)0.028
Starsteroidogenic acute regulatory protein0.027
Reep6receptor accessory protein 60.025
Amacralpha-methylacyl-CoA racemase0.025
Tcfebtranscription factor EB0.024
Nqo1NAD(P)H dehydrogenase, quinone 10.022
Higd2aHIG1 domain family, member 2A0.022
Gp9glycoprotein 9 (platelet)0.022
Acot13acyl-CoA thioesterase 130.022
Galmgalactose mutarotase0.021
Acp5acid phosphatase 5, tartrate resistant0.020
Hist1h2bchistone cluster 1, H2bc0.020
Sephs2selenophosphate synthetase 20.020
Rsc1a1regulatory solute carrier protein, family 1, member 10.019
Cpoxcoproporphyrinogen oxidase0.019
1110038D17RikRIKEN cDNA 1110038D17 gene0.019
Brp44brain protein 440.019
Lactb2lactamase, beta 20.018
Mt1metallothionein 10.018
Slc22a4solute carrier family 22 (organic cation transporter), member 40.018
Slc25a33solute carrier family 25, member 330.018
Fam83ffamily with sequence similarity 83, member F0.017
Mrvi1MRV integration site 10.017
Dpep1dipeptidase 1 (renal)0.017
Sh2d1aSH2 domain protein 1A0.017
Galnt6UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 60.017
Slc6a13solute carrier family 6 (neurotransmitter transporter, GABA), member 130.016
Slc25a45solute carrier family 25, member 450.016
BC031181cDNA sequence BC0311810.016
Srxn1sulfiredoxin 1 homolog (S. cerevisiae)0.016
Ctage5CTAGE family, member 50.016
Rbksribokinase0.016
Rhohras homolog gene family, member H0.016
Pak1ip1PAK1 interacting protein 10.016
Ctswcathepsin W0.015
Stc2stanniocalcin 20.015
Aldh9a1aldehyde dehydrogenase 9, subfamily A10.015
Eif5eukaryotic translation initiation factor 50.015
Cd27CD27 antigen0.015
H2-Oahistocompatibility 2, O region alpha locus0.015
Afpalpha fetoprotein0.014
Sit1suppression inducing transmembrane adaptor 10.014
Soat2sterol O-acyltransferase 20.014
Ell2elongation factor RNA polymerase II 20.014
Pdzk1ip1PDZK1 interacting protein 10.014
Mapk13mitogen-activated protein kinase 130.014
Plekha7pleckstrin homology domain containing, family A member 70.014
Ltb4r1leukotriene B4 receptor 10.014
Fechferrochelatase0.014
Tbceltubulin folding cofactor E-like0.014
Sod2superoxide dismutase 2, mitochondrial0.014
Pafah2platelet-activating factor acetylhydrolase 20.014
Hibadh3-hydroxyisobutyrate dehydrogenase0.014
Depdc7DEP domain containing 70.013
Sult2b1sulfotransferase family, cytosolic, 2B, member 10.013
Tacstd2tumor-associated calcium signal transducer 20.013
Akr1c13aldo-keto reductase family 1, member C130.013
Ltflactotransferrin0.013
Abhd5abhydrolase domain containing 50.013
5730469M10RikRIKEN cDNA 5730469M10 gene0.013
Tmem183atransmembrane protein 183A0.013
Acsl5acyl-CoA synthetase long-chain family member 50.013
Nmbneuromedin B0.013
Gclmglutamate-cysteine ligase, modifier subunit0.013
Map3k6mitogen-activated protein kinase kinase kinase 60.013
Dhrs11dehydrogenase/reductase (SDR family) member 110.013
Fabp4fatty acid binding protein 4, adipocyte0.013
Adh1alcohol dehydrogenase 1 (class I)0.012
Rnf128ring finger protein 1280.012
Lpin2lipin 20.012
9030617O03RikRIKEN cDNA 9030617O03 gene0.012
Slc35d1solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D10.012
Sfxn1sideroflexin 10.012
TprkbTp53rk binding protein0.012
Aqp7aquaporin 70.012
Msramethionine sulfoxide reductase A0.012
P2ry2purinergic receptor P2Y, G-protein coupled 20.011
Tmem40transmembrane protein 400.011
Slc25a13solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 130.011
Insl6insulin-like 60.011
Gsta3glutathione S-transferase, alpha 30.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GCLCglutamate-cysteine ligase, catalytic subunit0.952
GCLMglutamate-cysteine ligase, modifier subunit0.928
MAGEA11melanoma antigen family A, 110.094
MAPK3mitogen-activated protein kinase 30.067
ME1malic enzyme 1, NADP(+)-dependent, cytosolic0.043
CATcatalase0.037
NDUFS4NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)0.034
METRNmeteorin, glial cell differentiation regulator0.029
DECR12,4-dienoyl CoA reductase 1, mitochondrial0.027
TMED5transmembrane emp24 protein transport domain containing 50.020
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.018
PIRpirin (iron-binding nuclear protein)0.017
CCDC78coiled-coil domain containing 780.015
PHYHphytanoyl-CoA 2-hydroxylase0.014
SPSB3splA/ryanodine receptor domain and SOCS box containing 30.013
CHMP2Achromatin modifying protein 2A0.012
GSRglutathione reductase0.012
TSTthiosulfate sulfurtransferase (rhodanese)0.012
PINK1PTEN induced putative kinase 10.011
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.011
ACAA1acetyl-CoA acyltransferase 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ubqln1ubiquilin 10.086
Pgrmc1progesterone receptor membrane component 10.079
UgdhUDP-glucose dehydrogenase0.068
Akr1b8aldo-keto reductase family 1, member B80.045
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.043
Cd14CD14 molecule0.043
Txnrd1thioredoxin reductase 10.028
Chac2ChaC, cation transport regulator homolog 2 (E. coli)0.024
Nqo1NAD(P)H dehydrogenase, quinone 10.024
Creg1cellular repressor of E1A-stimulated genes 10.023
Pctpphosphatidylcholine transfer protein0.021
Ephx1epoxide hydrolase 1, microsomal0.021
Gsta5glutathione S-transferase Yc2 subunit0.021
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.019
Anpepalanyl (membrane) aminopeptidase0.019
Uqcrfs1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.019
Gsrglutathione reductase0.019
Catcatalase0.017
StradbSTE20-related kinase adaptor beta0.016
Polr3kpolymerase (RNA) III (DNA directed) polypeptide K0.016
Ptgr1prostaglandin reductase 10.015
Rdh10retinol dehydrogenase 10 (all-trans)0.015
Gsta3glutathione S-transferase A30.014
Mgst1microsomal glutathione S-transferase 10.014
Slc40a1solute carrier family 39 (iron-regulated transporter), member 10.014
Rarres2retinoic acid receptor responder (tazarotene induced) 20.014
Akr7a3aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)0.014
March5membrane-associated ring finger (C3HC4) 50.013
Cthcystathionase (cystathionine gamma-lyase)0.013
Hrsp12heat-responsive protein 120.012
Pdlim2PDZ and LIM domain 20.012
Cyb5acytochrome b5 type A (microsomal)0.012
Gabarapl2GABA(A) receptor-associated protein like 20.012
Etfaelectron-transfer-flavoprotein, alpha polypeptide0.012
Gstm2glutathione S-transferase mu 20.011
Srxn1sulfiredoxin 1 homolog (S. cerevisiae)0.011
Lonp2lon peptidase 2, peroxisomal0.011
MlxMAX-like protein X0.011
Amacralpha-methylacyl-CoA racemase0.011
Phyhd1phytanoyl-CoA dioxygenase domain containing 10.011
Nit2nitrilase family, member 20.010
Ebpemopamil binding protein (sterol isomerase)0.010
Pecrperoxisomal trans-2-enoyl-CoA reductase0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism