The network for 'cellular response to prostaglandin stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to prostaglandin stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.

NameDescriptionProbabilityFunc Analog Organism
Cav1caveolin 1, caveolae protein0.658
Sfrp2secreted frizzled-related protein 20.544
Leprleptin receptor0.452
Agpat21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)0.444
Adipoqadiponectin, C1Q and collagen domain containing0.239
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.218
Rb1retinoblastoma 10.214
Otx2orthodenticle homolog 2 (Drosophila)0.207
Fgf10fibroblast growth factor 100.164
Ncoa3nuclear receptor coactivator 30.117
Emx1empty spiracles homolog 1 (Drosophila)0.111
Foxf2forkhead box F20.104
Tlr2toll-like receptor 20.102
Mitfmicrophthalmia-associated transcription factor0.091
Lrp1low density lipoprotein receptor-related protein 10.090
Plin1perilipin 10.089
Gli3GLI-Kruppel family member GLI30.084
Adrb3adrenergic receptor, beta 30.083
Pcsk5proprotein convertase subtilisin/kexin type 50.081
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.080
Insrinsulin receptor0.077
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.075
Mab21l1mab-21-like 1 (C. elegans)0.070
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.068
Bscl2Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)0.067
Kcnj1potassium inwardly-rectifying channel, subfamily J, member 10.067
Ntf3neurotrophin 30.067
Gdf11growth differentiation factor 110.065
Isl1ISL1 transcription factor, LIM/homeodomain0.062
Hif1ahypoxia inducible factor 1, alpha subunit0.062
Nr2e1nuclear receptor subfamily 2, group E, member 10.060
Emx2empty spiracles homolog 2 (Drosophila)0.059
Neurod1neurogenic differentiation 10.059
Egfrepidermal growth factor receptor0.058
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.056
Ghrgrowth hormone receptor0.053
Foxc1forkhead box C10.049
Mt1metallothionein 10.048
FasFas (TNF receptor superfamily member 6)0.048
Stat3signal transducer and activator of transcription 30.048
Clockcircadian locomotor output cycles kaput0.048
Scd1stearoyl-Coenzyme A desaturase 10.047
Pitx2paired-like homeodomain transcription factor 20.046
Thbs2thrombospondin 20.045
Sox2SRY-box containing gene 20.044
Gcet2germinal center expressed transcript 20.044
Col1a1collagen, type I, alpha 10.043
Mt2metallothionein 20.042
Lpin1lipin 10.042
Nos1nitric oxide synthase 1, neuronal0.041
Slc12a1solute carrier family 12, member 10.040
Esr1estrogen receptor 1 (alpha)0.040
Il1r1interleukin 1 receptor, type I0.039
Mab21l2mab-21-like 2 (C. elegans)0.039
Cxcl12chemokine (C-X-C motif) ligand 120.038
Ppargperoxisome proliferator activated receptor gamma0.037
Prdm16PR domain containing 160.037
Otx1orthodenticle homolog 1 (Drosophila)0.036
Pax2paired box gene 20.035
Spp1secreted phosphoprotein 10.035
Arxaristaless related homeobox0.035
Ptgs2prostaglandin-endoperoxide synthase 20.034
Vsx2visual system homeobox 20.034
Tlr4toll-like receptor 40.034
Dkk2dickkopf homolog 2 (Xenopus laevis)0.033
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.032
Spnb1spectrin beta 10.032
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.032
Pou4f2POU domain, class 4, transcription factor 20.031
Lmx1bLIM homeobox transcription factor 1 beta0.031
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.030
Mep1ameprin 1 alpha0.029
Htra3HtrA serine peptidase 30.029
Lyl1lymphoblastomic leukemia 10.028
Ptk2PTK2 protein tyrosine kinase 20.028
Ifngr1interferon gamma receptor 10.027
F2rl2coagulation factor II (thrombin) receptor-like 20.027
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.026
Wnt5awingless-related MMTV integration site 5A0.026
Sfrp4secreted frizzled-related protein 40.026
Slc6a4solute carrier family 6 (neurotransmitter transporter, serotonin), member 40.026
Slc5a11solute carrier family 5 (sodium/glucose cotransporter), member 110.025
Ctskcathepsin K0.024
Clcnkachloride channel Ka0.024
Foxg1forkhead box G10.024
Cideccell death-inducing DFFA-like effector c0.024
Rem1rad and gem related GTP binding protein 10.023
Insm1insulinoma-associated 10.023
C3complement component 30.023
Ptenphosphatase and tensin homolog0.023
Gpd2glycerol phosphate dehydrogenase 2, mitochondrial0.022
Avpr1aarginine vasopressin receptor 1A0.022
6530401N04RikRIKEN cDNA 6530401N04 gene0.022
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fgfr2fibroblast growth factor receptor 20.480
rbp4retinol binding protein 4, plasma0.354
nkx2.2aNK2 transcription factor related 2a0.333
wif1wnt inhibitory factor 10.313
otx2orthodenticle homolog 20.310
mdkbmidkine-related growth factor b0.246
ascl1aachaete-scute complex-like 1a (Drosophila)0.213
gli2aGLI-Kruppel family member GLI2a0.209
epha4aeph receptor A4a0.167
ca2carbonic anhydrase II0.147
myh11amyosin, heavy polypeptide 11, smooth muscle a0.144
six3bsine oculis homeobox homolog 3b0.127
spry4sprouty (Drosophila) homolog 40.121
cx43.4connexin 43.40.110
efnb2aephrin B2a0.108
foxe3forkhead box E30.101
metmet proto-oncogene (hepatocyte growth factor receptor)0.091
igfbp2ainsulin-like growth factor binding protein 2a0.084
hmx4H6 family homeobox 40.079
pax6apaired box gene 6a0.077
raraaretinoic acid receptor, alpha a0.075
sox1aSRY-box containing gene 1a0.075
kiss1KiSS-1 metastasis-suppressor0.071
bhmtbetaine-homocysteine methyltransferase0.064
mcoln1mucolipin 10.064
sox2SRY-box containing gene 20.062
lgals3llectin, galactoside-binding, soluble, 3 (galectin 3)-like0.060
vcanaversican a0.060
crb2acrumbs homolog 2a0.055
foxi3aforkhead box I3a0.052
gamtguanidinoacetate N-methyltransferase0.050
mgaMAX gene associated0.049
gata3GATA-binding protein 30.048
wnt4awingless-type MMTV integration site family, member 4a0.047
mbnl2muscleblind-like 2 (Drosophila)0.046
has2hyaluronan synthase 20.045
foxa1forkhead box A10.042
ptgs2aprostaglandin-endoperoxide synthase 2a0.042
ptger4aprostaglandin E receptor 4 (subtype EP4) a0.040
fabp11afatty acid binding protein 11a0.040
fzd10frizzled homolog 100.038
fn1bfibronectin 1b0.037
pax6bpaired box gene 6b0.037
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.036
pitx3paired-like homeodomain transcription factor 30.036
meis2.2myeloid ecotropic viral integration site 2.20.036
pwp2hPWP2 periodic tryptophan protein homolog (yeast)0.035
wnt3awingless-type MMTV integration site family, member 3A0.034
aldh2baldehyde dehydrogenase 2b0.034
prox1prospero-related homeobox gene 10.033
mapk7mitogen-activated protein kinase 70.033
nfe2l2nuclear factor (erythroid-derived 2)-like 20.032
diexfdigestive organ expansion factor homolog0.032
sat1aspermidine/spermine N1-acetyltransferase 1a0.031
foxa3forkhead box A30.031
gfergrowth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)0.030
id2ainhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a0.030
otx1borthodenticle homolog 1b0.029
sparcsecreted acidic cysteine rich glycoprotein0.029
col4a5collagen, type IV, alpha 5 (Alport syndrome)0.029
fgf8afibroblast growth factor 8 a0.029
frzbfrizzled-related protein0.028
atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase0.028
gata5GATA-binding protein 50.027
cebpdCCAAT/enhancer binding protein (C/EBP), delta0.027
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.026
mnx1motor neuron and pancreas homeobox 10.025
aplp2amyloid beta (A4) precursor-like protein 20.025
adrb2aadrenergic receptor, beta 2a0.025
cd63Cd63 antigen0.025
rasl11bRAS-like, family 11, member B0.024
pck2phosphoenolpyruvate carboxykinase 2 (mitochondrial)0.024
keap1akelch-like ECH-associated protein 1a0.024
ghragrowth hormone receptor a0.024
pdlim1PDZ and LIM domain 1 (elfin)0.023
LOC100003330melanocortin-2 receptor accessory protein 2-like0.023
angptl2angiopoietin-like 20.023
aldobaldolase b, fructose-bisphosphate0.023
prdm5PR domain containing 50.023
igf2ainsulin-like growth factor 2a0.022
six3asine oculis homeobox homolog 3a0.022
egfraepidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)0.022
anxa5bannexin A5b0.022
eml2echinoderm microtubule associated protein like 20.021
cadm3cell adhesion molecule 30.021
trpv6transient receptor potential cation channel, subfamily V, member 60.021
hsp90a.1heat shock protein 90-alpha 10.020
ef1aelongation factor 1-alpha0.020
il8interleukin 80.020
fabp2fatty acid binding protein 2, intestinal0.020
olig2oligodendrocyte lineage transcription factor 20.020
sfrp5secreted frizzled-related protein 50.020
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.020
tbx2bT-box 2b0.019
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)1.000
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)1.000
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.999
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.979
HNF4Ahepatocyte nuclear factor 4, alpha0.471
ESRRGestrogen-related receptor gamma0.461
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.081
IPO13importin 130.075
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 30.072
ZHX1zinc fingers and homeoboxes 10.061
CTGFconnective tissue growth factor0.055
ACACAacetyl-CoA carboxylase alpha0.054
CDX2caudal type homeobox 20.048
LHX2LIM homeobox 20.039
AKR1C4aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)0.038
GATA5GATA binding protein 50.030
EN1engrailed homeobox 10.025
FBLN2fibulin 20.025
GPX2glutathione peroxidase 2 (gastrointestinal)0.025
NTRK2neurotrophic tyrosine kinase, receptor, type 20.025
FBLN1fibulin 10.023
AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase)0.022
HAND2heart and neural crest derivatives expressed 20.021
SIX3SIX homeobox 30.020
AADACarylacetamide deacetylase (esterase)0.020
PDZK1PDZ domain containing 10.020
MAGEA11melanoma antigen family A, 110.019
ANXA10annexin A100.018
FGF3fibroblast growth factor 30.018
S100A10S100 calcium binding protein A100.018
NQO1NAD(P)H dehydrogenase, quinone 10.018
SOX2SRY (sex determining region Y)-box 20.018
ZIC1Zic family member 1 (odd-paired homolog, Drosophila)0.018
PIRpirin (iron-binding nuclear protein)0.017
NR1I2nuclear receptor subfamily 1, group I, member 20.017
AOC3amine oxidase, copper containing 3 (vascular adhesion protein 1)0.016
BBOX1butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 10.015
FBN2fibrillin 20.015
NEURLneuralized homolog (Drosophila)0.015
HSD17B2hydroxysteroid (17-beta) dehydrogenase 20.015
RARAretinoic acid receptor, alpha0.015
NCOA1nuclear receptor coactivator 10.015
MYO6myosin VI0.015
WIF1WNT inhibitory factor 10.015
CORO1Ccoronin, actin binding protein, 1C0.015
AGTangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.015
ALX1ALX homeobox 10.015
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.015
CYP3A5cytochrome P450, family 3, subfamily A, polypeptide 50.014
CYP4F12cytochrome P450, family 4, subfamily F, polypeptide 120.014
PCK1phosphoenolpyruvate carboxykinase 1 (soluble)0.014
ABCC3ATP-binding cassette, sub-family C (CFTR/MRP), member 30.014
NOVnephroblastoma overexpressed gene0.014
FABP4fatty acid binding protein 4, adipocyte0.014
CYP4F3cytochrome P450, family 4, subfamily F, polypeptide 30.014
CELF3CUGBP, Elav-like family member 30.013
GABREgamma-aminobutyric acid (GABA) A receptor, epsilon0.013
ACTN1actinin, alpha 10.013
ADH1Calcohol dehydrogenase 1C (class I), gamma polypeptide0.013
CHRDL1chordin-like 10.013
TIMP4TIMP metallopeptidase inhibitor 40.013
SALL1sal-like 1 (Drosophila)0.013
GNGT1guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 10.012
MAB21L1mab-21-like 1 (C. elegans)0.012
MFAP4microfibrillar-associated protein 40.012
POU3F1POU class 3 homeobox 10.012
CYP4F11cytochrome P450, family 4, subfamily F, polypeptide 110.012
C10orf116chromosome 10 open reading frame 1160.012
LIPClipase, hepatic0.012
PPARAperoxisome proliferator-activated receptor alpha0.012
CD44CD44 molecule (Indian blood group)0.012
WNT2wingless-type MMTV integration site family member 20.012
RARRES2retinoic acid receptor responder (tazarotene induced) 20.012
NPR1natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)0.011
FABP7fatty acid binding protein 7, brain0.011
FABP1fatty acid binding protein 1, liver0.011
UGT1A3UDP glucuronosyltransferase 1 family, polypeptide A30.011
PDLIM5PDZ and LIM domain 50.011
CXCL12chemokine (C-X-C motif) ligand 120.011
GBX2gastrulation brain homeobox 20.011
CYFIP1cytoplasmic FMR1 interacting protein 10.011
NPAS1neuronal PAS domain protein 10.011
CABP1calcium binding protein 10.011
CDR1cerebellar degeneration-related protein 1, 34kDa0.011
APOFapolipoprotein F0.011
PDGFRLplatelet-derived growth factor receptor-like0.011
IL1RAPL1interleukin 1 receptor accessory protein-like 10.011
SIX1SIX homeobox 10.011
PITX2paired-like homeodomain 20.011
TBX1T-box 10.011
SFRP4secreted frizzled-related protein 40.011
BFSP1beaded filament structural protein 1, filensin0.010
RBP4retinol binding protein 4, plasma0.010
TTYH1tweety homolog 1 (Drosophila)0.010
LPAR4lysophosphatidic acid receptor 40.010
NR1H4nuclear receptor subfamily 1, group H, member 40.010
FZD8frizzled homolog 8 (Drosophila)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loxlysyl oxidase0.060
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.057
G6pcglucose-6-phosphatase, catalytic subunit0.046
Postnperiostin, osteoblast specific factor0.041
Lamc1laminin, gamma 10.032
LOC293989cytochrome P450-like0.025
Rup2urinary protein 20.024
Mosc1MOCO sulphurase C-terminal domain containing 10.020
Scn5asodium channel, voltage-gated, type V, alpha subunit0.018
Ptprhprotein tyrosine phosphatase, receptor type, H0.017
P2ry4pyrimidinergic receptor P2Y, G-protein coupled, 40.016
Obp1fodorant binding protein I f0.016
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.015
RorbRAR-related orphan receptor B0.015
Ceacam1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.015
Acot12acyl-CoA thioesterase 120.014
Hnf4ahepatocyte nuclear factor 4, alpha0.014
Ces1ccarboxylesterase 1C0.013
Fgd4FYVE, RhoGEF and PH domain containing 40.013
Ttc36tetratricopeptide repeat domain 360.013
Dnase1deoxyribonuclease I0.013
Slc23a1solute carrier family 23 (nucleobase transporters), member 10.012
Col12a1collagen, type XII, alpha 10.011
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.011
Slco2a1solute carrier organic anion transporter family, member 2a10.011
Slc22a1solute carrier family 22 (organic cation transporter), member 10.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism