Process View
The network for 'regulation of phospholipid catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Dab1 | disabled homolog 1 (Drosophila) | 0.993 | |
Apoe | apolipoprotein E | 0.954 | |
Cav1 | caveolin 1, caveolae protein | 0.918 | |
Sqle | squalene epoxidase | 0.291 | |
Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.283 | |
Lrp1 | low density lipoprotein receptor-related protein 1 | 0.209 | |
Cyp51 | cytochrome P450, family 51 | 0.181 | |
Sc4mol | sterol-C4-methyl oxidase-like | 0.142 | |
Hmgcs1 | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 | 0.123 | |
Il1r1 | interleukin 1 receptor, type I | 0.108 | |
Lss | lanosterol synthase | 0.094 | |
Reln | reelin | 0.089 | |
Hsd3b7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 0.087 | |
Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.086 | |
Pparg | peroxisome proliferator activated receptor gamma | 0.085 | |
Ccl2 | chemokine (C-C motif) ligand 2 | 0.083 | |
Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.083 | |
Igh | immunoglobulin heavy chain complex | 0.077 | |
Vldlr | very low density lipoprotein receptor | 0.062 | |
Dhcr7 | 7-dehydrocholesterol reductase | 0.062 | |
Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.061 | |
Fbn1 | fibrillin 1 | 0.057 | |
Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.054 | |
Npc1 | Niemann Pick type C1 | 0.052 | |
Idi1 | isopentenyl-diphosphate delta isomerase | 0.049 | |
Lrp8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.047 | |
Mvd | mevalonate (diphospho) decarboxylase | 0.047 | |
Lpin1 | lipin 1 | 0.046 | |
Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.046 | |
Ghr | growth hormone receptor | 0.045 | |
Crkl | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.041 | |
Agtr1a | angiotensin II receptor, type 1a | 0.040 | |
Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.037 | |
Ldlr | low density lipoprotein receptor | 0.035 | |
Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 | 0.031 | |
Hsd17b7 | hydroxysteroid (17-beta) dehydrogenase 7 | 0.029 | |
Fabp4 | fatty acid binding protein 4, adipocyte | 0.029 | |
Slc12a6 | solute carrier family 12, member 6 | 0.028 | |
Lpl | lipoprotein lipase | 0.027 | |
Fas | Fas (TNF receptor superfamily member 6) | 0.026 | |
Dhcr24 | 24-dehydrocholesterol reductase | 0.026 | |
Sc5d | sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) | 0.026 | |
Kcnj10 | potassium inwardly-rectifying channel, subfamily J, member 10 | 0.025 | |
Cfh | complement component factor h | 0.025 | |
Lcat | lecithin cholesterol acyltransferase | 0.024 | |
Abhd5 | abhydrolase domain containing 5 | 0.022 | |
Soat1 | sterol O-acyltransferase 1 | 0.022 | |
Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.022 | |
Hsd11b1 | hydroxysteroid 11-beta dehydrogenase 1 | 0.022 | |
Tgfbr1 | transforming growth factor, beta receptor I | 0.021 | |
Stard4 | StAR-related lipid transfer (START) domain containing 4 | 0.021 | |
Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | 0.020 | |
Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.020 | |
Gjb2 | gap junction protein, beta 2 | 0.020 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.020 | |
Lepr | leptin receptor | 0.018 | |
Bcl6 | B-cell leukemia/lymphoma 6 | 0.018 | |
Btk | Bruton agammaglobulinemia tyrosine kinase | 0.016 | |
Cd36 | CD36 antigen | 0.016 | |
Tlr2 | toll-like receptor 2 | 0.016 | |
Cd40 | CD40 antigen | 0.016 | |
Klf15 | Kruppel-like factor 15 | 0.016 | |
Gba | glucosidase, beta, acid | 0.015 | |
Tlr4 | toll-like receptor 4 | 0.015 | |
Adamts1 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 | 0.015 | |
Ncoa3 | nuclear receptor coactivator 3 | 0.014 | |
Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) | 0.014 | |
Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.014 | |
Rora | RAR-related orphan receptor alpha | 0.013 | |
Man2a1 | mannosidase 2, alpha 1 | 0.012 | |
Pygl | liver glycogen phosphorylase | 0.012 | |
Bpnt1 | bisphosphate 3'-nucleotidase 1 | 0.012 | |
Flt1 | FMS-like tyrosine kinase 1 | 0.012 | |
Srebf2 | sterol regulatory element binding factor 2 | 0.011 | |
Pdk4 | pyruvate dehydrogenase kinase, isoenzyme 4 | 0.011 | |
Timp3 | tissue inhibitor of metalloproteinase 3 | 0.011 | |
Aacs | acetoacetyl-CoA synthetase | 0.011 | |
Stat3 | signal transducer and activator of transcription 3 | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.584 | |
NUMB | numb homolog (Drosophila) | 0.053 | |
PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.051 | |
PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.048 | |
APOE | apolipoprotein E | 0.040 | |
NOXA1 | NADPH oxidase activator 1 | 0.029 | |
MAPT | microtubule-associated protein tau | 0.026 | |
ZNF71 | zinc finger protein 71 | 0.026 | |
CCDC115 | coiled-coil domain containing 115 | 0.023 | |
PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.019 | |
CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.017 | |
PRKCZ | protein kinase C, zeta | 0.017 | |
PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.017 | |
MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.015 | |
FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.015 | |
CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.014 | |
APOA1 | apolipoprotein A-I | 0.014 | |
DCTN1 | dynactin 1 | 0.013 | |
HP | haptoglobin | 0.013 | |
CYBA | cytochrome b-245, alpha polypeptide | 0.013 | |
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.013 | |
NCF1 | neutrophil cytosolic factor 1 | 0.012 | |
RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.012 | |
VHL | von Hippel-Lindau tumor suppressor | 0.012 | |
CDCP1 | CUB domain containing protein 1 | 0.010 | |
TRIM9 | tripartite motif containing 9 | 0.010 | |
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.010 | |
ALB | albumin | 0.010 |