The network for 'regulation of skeletal muscle adaptation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of skeletal muscle adaptation

Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.

NameDescriptionProbabilityFunc Analog Organism
Tnnc2troponin C2, fast0.897
Hrchistidine rich calcium binding protein0.875
Ldb3LIM domain binding 30.818
Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit0.724
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.678
Yap1yes-associated protein 10.672
Tnni2troponin I, skeletal, fast 20.601
Actn2actinin alpha 20.525
Casq1calsequestrin 10.467
Actn3actinin alpha 30.465
Myom2myomesin 20.419
Tnnt3troponin T3, skeletal, fast0.403
Tnnt2troponin T2, cardiac0.311
Ryr1ryanodine receptor 1, skeletal muscle0.279
Atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.266
Csrp3cysteine and glycine-rich protein 30.256
Mylpfmyosin light chain, phosphorylatable, fast skeletal muscle0.243
Srpk3serine/arginine-rich protein specific kinase 30.229
Myh1myosin, heavy polypeptide 1, skeletal muscle, adult0.228
Ckmt2creatine kinase, mitochondrial 20.227
Actc1actin, alpha, cardiac muscle 10.189
Cox6a2cytochrome c oxidase, subunit VI a, polypeptide 20.176
Myom1myomesin 10.172
Xirp1xin actin-binding repeat containing 10.172
Myh4myosin, heavy polypeptide 4, skeletal muscle0.159
Myh3myosin, heavy polypeptide 3, skeletal muscle, embryonic0.151
Pgam2phosphoglycerate mutase 20.151
Nfatc3nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 30.145
Myh8myosin, heavy polypeptide 8, skeletal muscle, perinatal0.142
Myh7myosin, heavy polypeptide 7, cardiac muscle, beta0.137
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)0.128
Tnnt1troponin T1, skeletal, slow0.118
Myl3myosin, light polypeptide 30.117
Gtf2ird1general transcription factor II I repeat domain-containing 10.115
Acta1actin, alpha 1, skeletal muscle0.115
Cox8bcytochrome c oxidase, subunit VIIIb0.113
Mybphmyosin binding protein H0.105
Myoz1myozenin 10.104
Gtf2igeneral transcription factor II I0.100
Myl1myosin, light polypeptide 10.089
Skiski sarcoma viral oncogene homolog (avian)0.087
Pygmmuscle glycogen phosphorylase0.086
Chrna1cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)0.081
Nfatc4nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 40.081
Apobec2apolipoprotein B mRNA editing enzyme, catalytic polypeptide 20.080
Trim54tripartite motif-containing 540.076
Mef2amyocyte enhancer factor 2A0.074
Nrapnebulin-related anchoring protein0.070
Casq2calsequestrin 20.069
Wnt11wingless-related MMTV integration site 110.068
Myh2myosin, heavy polypeptide 2, skeletal muscle, adult0.067
Tnni3troponin I, cardiac 30.064
Hspb7heat shock protein family, member 7 (cardiovascular)0.061
Tead1TEA domain family member 10.061
Tnnc1troponin C, cardiac/slow skeletal0.059
Wwtr1WW domain containing transcription regulator 10.051
Ckmcreatine kinase, muscle0.050
Cav3caveolin 30.050
Cacng1calcium channel, voltage-dependent, gamma subunit 10.044
Map3k5mitogen-activated protein kinase kinase kinase 50.041
Tead2TEA domain family member 20.039
Lmod2leiomodin 2 (cardiac)0.036
Ptpn11protein tyrosine phosphatase, non-receptor type 110.035
Ptpn14protein tyrosine phosphatase, non-receptor type 140.035
Fbn2fibrillin 20.034
Cox7a1cytochrome c oxidase, subunit VIIa 10.033
Oxr1oxidation resistance 10.031
Col17a1collagen, type XVII, alpha 10.030
Myl7myosin, light polypeptide 7, regulatory0.030
Kcnj2potassium inwardly-rectifying channel, subfamily J, member 20.028
Rpl3lribosomal protein L3-like0.027
Tnni1troponin I, skeletal, slow 10.027
Hhathedgehog acyltransferase0.027
Myoz2myozenin 20.025
RradRas-related associated with diabetes0.024
Flncfilamin C, gamma0.023
Itgb1bp2integrin beta 1 binding protein 20.023
Trim63tripartite motif-containing 630.023
Myl4myosin, light polypeptide 40.023
Tpm2tropomyosin 2, beta0.023
Gdpd5glycerophosphodiester phosphodiesterase domain containing 50.022
Sos2son of sevenless homolog 2 (Drosophila)0.022
Txlnbtaxilin beta0.021
Myf6myogenic factor 60.021
Prkceprotein kinase C, epsilon0.021
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.020
Dlk1delta-like 1 homolog (Drosophila)0.020
Smpxsmall muscle protein, X-linked0.019
Vegfavascular endothelial growth factor A0.019
Notch4Notch gene homolog 4 (Drosophila)0.019
Lmod3leiomodin 3 (fetal)0.018
Fbxo32F-box protein 320.018
Hfe2hemochromatosis type 2 (juvenile) (human homolog)0.018
Akap5A kinase (PRKA) anchor protein 50.018
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Caenorhabditis elegans
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Danio rerio
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Drosophila melanogaster
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism