The network for 'nucleosome disassembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nucleosome disassembly

The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.

NameDescriptionProbabilityFunc Analog Organism
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 41.000
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 11.000
Arid1aAT rich interactive domain 1A (SWI-like)1.000
Arid1bAT rich interactive domain 1B (SWI-like)1.000
Smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 21.000
Smarcb1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 11.000
Smarcc2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 21.000
Hist1h1chistone cluster 1, H1c1.000
Smarcd3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 30.999
Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.995
Hist1h2bphistone cluster 1, H2bp0.993
Hist1h2brhistone cluster 1 H2br0.992
Smarce1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.989
Hist2h3c1histone cluster 2, H3c10.987
Tcfcp2l1transcription factor CP2-like 10.961
Hist1h2bmhistone cluster 1, H2bm0.960
Prmt5protein arginine N-methyltransferase 50.944
Sin3atranscriptional regulator, SIN3A (yeast)0.892
Creb1cAMP responsive element binding protein 10.882
Hist1h2bbhistone cluster 1, H2bb0.870
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.796
Hist2h3c2-pshistone cluster 2, H3c2, pseudogene0.752
Numa1nuclear mitotic apparatus protein 10.683
Hist1h2bkhistone cluster 1, H2bk0.668
Hist1h2bghistone cluster 1, H2bg0.579
Hist1h2bfhistone cluster 1, H2bf0.439
Hist1h2bahistone cluster 1, H2ba0.427
Hist1h2bqhistone cluster 1, H2bq0.367
Brd4bromodomain containing 40.357
Hist2h2aa2histone cluster 2, H2aa20.350
Whsc1Wolf-Hirschhorn syndrome candidate 1 (human)0.317
Trp53transformation related protein 530.316
Hist1h2aahistone cluster 1, H2aa0.289
Sall4sal-like 4 (Drosophila)0.281
Hist1h1bhistone cluster 1, H1b0.278
Hdac1histone deacetylase 10.249
Hist1h4hhistone cluster 1, H4h0.199
E2f1E2F transcription factor 10.194
Hist1h3ghistone cluster 1, H3g0.188
Kdm4alysine (K)-specific demethylase 4A0.184
Chd4chromodomain helicase DNA binding protein 40.182
Hist1h2bjhistone cluster 1, H2bj0.171
Brd3bromodomain containing 30.157
L3mbtl2l(3)mbt-like 2 (Drosophila)0.150
Polr2apolymerase (RNA) II (DNA directed) polypeptide A0.147
Rb1retinoblastoma 10.143
E2f4E2F transcription factor 40.142
Hist1h2blhistone cluster 1, H2bl0.138
Kdm4blysine (K)-specific demethylase 4B0.133
Hist1h2bchistone cluster 1, H2bc0.132
Sox2SRY-box containing gene 20.121
Hist1h4mhistone cluster 1, H4m0.114
Hist2h2behistone cluster 2, H2be0.094
Hist1h1ahistone cluster 1, H1a0.093
Hist1h1dhistone cluster 1, H1d0.090
Hist1h2bnhistone cluster 1, H2bn0.079
Pbrm1polybromo 10.078
Plk1polo-like kinase 1 (Drosophila)0.075
Hist1h2abhistone cluster 1, H2ab0.070
Hist2h4histone cluster 2, H40.069
Chaf1achromatin assembly factor 1, subunit A (p150)0.068
Ss18l1synovial sarcoma translocation gene on chromosome 18-like 10.066
Hist1h2aehistone cluster 1, H2ae0.066
Mcm2minichromosome maintenance deficient 2 mitotin (S. cerevisiae)0.060
Hist2h2abhistone cluster 2, H2ab0.058
Smad1MAD homolog 1 (Drosophila)0.058
Ep300E1A binding protein p3000.057
Hist1h2akhistone cluster 1, H2ak0.056
Hist1h3chistone cluster 1, H3c0.056
Srrm2serine/arginine repetitive matrix 20.055
Kdm6bKDM1 lysine (K)-specific demethylase 6B0.055
Hist1h2bhhistone cluster 1, H2bh0.054
Hist4h4histone cluster 4, H40.053
H2afyH2A histone family, member Y0.053
Hist1h4fhistone cluster 1, H4f0.048
Tnrc6ctrinucleotide repeat containing 6C0.043
Hist1h3ahistone cluster 1, H3a0.043
Ss18synovial sarcoma translocation, Chromosome 180.041
Tcf19transcription factor 190.037
Birc5baculoviral IAP repeat-containing 50.036
Rnf38ring finger protein 380.034
H2afvH2A histone family, member V0.033
Hist1h2behistone cluster 1, H2be0.032
Dpf2D4, zinc and double PHD fingers family 20.032
Eif4g3eukaryotic translation initiation factor 4 gamma, 30.029
Gltscr1glioma tumor suppressor candidate region gene 10.029
Msl1male-specific lethal 1 homolog (Drosophila)0.025
Ubbubiquitin B0.023
Nacc1nucleus accumbens associated 1, BEN and BTB (POZ) domain containing0.022
Hist1h4dhistone cluster 1, H4d0.022
Gm3244predicted pseudogene 32440.022
IscuIscU iron-sulfur cluster scaffold homolog (E. coli)0.021
Hist1h3fhistone cluster 1, H3f0.020
Bloc1s1biogenesis of lysosome-related organelles complex-1, subunit 10.020
Pou2f1POU domain, class 2, transcription factor 10.019
Gsk3bglycogen synthase kinase 3 beta0.019
Hist1h3dhistone cluster 1, H3d0.019
Chd7chromodomain helicase DNA binding protein 70.019
B9d1B9 protein domain 10.017
BC053749cDNA sequence BC0537490.017
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 41.000
ARID1AAT rich interactive domain 1A (SWI-like)0.998
HIST1H2AChistone cluster 1, H2ac0.998
HIST1H2BDhistone cluster 1, H2bd0.997
HIST1H2BFhistone cluster 1, H2bf0.995
HIST1H2BEhistone cluster 1, H2be0.994
HIST1H2BGhistone cluster 1, H2bg0.993
HIST1H1Chistone cluster 1, H1c0.986
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.982
HIST1H3Dhistone cluster 1, H3d0.970
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.966
HIST1H2BIhistone cluster 1, H2bi0.952
HIST1H2BHhistone cluster 1, H2bh0.946
ARID1BAT rich interactive domain 1B (SWI1-like)0.927
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.912
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.911
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.868
HIST1H2BKhistone cluster 1, H2bk0.856
HIST1H2AJhistone cluster 1, H2aj0.814
PBRM1polybromo 10.800
HIST2H2BEhistone cluster 2, H2be0.787
HIST1H2AEhistone cluster 1, H2ae0.784
HIST1H2BChistone cluster 1, H2bc0.744
ARID2AT rich interactive domain 2 (ARID, RFX-like)0.606
HIST2H2AA4histone cluster 2, H2aa40.589
HIST1H2AIhistone cluster 1, H2ai0.497
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.383
HIST1H3Hhistone cluster 1, H3h0.331
HIST1H4Hhistone cluster 1, H4h0.249
CHAF1Bchromatin assembly factor 1, subunit B (p60)0.112
HIST1H3Ahistone cluster 1, H3a0.095
HIST1H2AMhistone cluster 1, H2am0.090
CBX5chromobox homolog 50.082
HIST1H2BMhistone cluster 1, H2bm0.081
HIST1H2BJhistone cluster 1, H2bj0.078
CARM1coactivator-associated arginine methyltransferase 10.038
HIST1H2BBhistone cluster 1, H2bb0.035
NCOR1nuclear receptor corepressor 10.032
HIST1H3Ghistone cluster 1, H3g0.032
CDAN1congenital dyserythropoietic anemia, type I0.031
HIST1H2ALhistone cluster 1, H2al0.030
HIST1H4Ahistone cluster 1, H4a0.023
HIST1H2AGhistone cluster 1, H2ag0.022
HIST1H4Dhistone cluster 1, H4d0.022
HIST1H2BOhistone cluster 1, H2bo0.022
HIST1H2ABhistone cluster 1, H2ab0.020
TLK1tousled-like kinase 10.019
HIST1H4Bhistone cluster 1, H4b0.018
HIST2H2AA3histone cluster 2, H2aa30.017
HIST1H2AKhistone cluster 1, H2ak0.015
SS18synovial sarcoma translocation, chromosome 180.013
HIST1H3Bhistone cluster 1, H3b0.013
HIST1H4Jhistone cluster 1, H4j0.012
HIST1H4Ehistone cluster 1, H4e0.012
CHD4chromodomain helicase DNA binding protein 40.012
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 20.011
SIN3ASIN3 homolog A, transcription regulator (yeast)0.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Actr1aARP1 actin-related protein 1 homolog A, centractin alpha (yeast)0.141
Ubtfupstream binding transcription factor, RNA polymerase I0.102
Rnf10ring finger protein 100.099
RGD1309414similar to KIAA0913 protein0.050
Pik3r2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.021
LOC100360501ribonuclease inhibitor-like0.018
Puf60poly-U binding splicing factor 600.017
GeftRhoA/RAC/CDC42 exchange factor0.016
Akt1v-akt murine thymoma viral oncogene homolog 10.015
Chpfchondroitin polymerizing factor0.015
Usp5ubiquitin specific peptidase 5 (isopeptidase T)0.014
Pdap1PDGFA associated protein 10.014
Fam195bfamily with sequence similarity 195, member B0.014
Trim28tripartite motif-containing 280.014
Dhx30DEAH (Asp-Glu-Ala-His) box polypeptide 300.013
Zc3h7bzinc finger CCCH-type containing 7B0.013
Bat2HLA-B associated transcript 20.012
Gtf3c1general transcription factor IIIC, polypeptide 1, alpha0.011
Safbscaffold attachment factor B0.011
Acin1apoptotic chromatin condensation inducer 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RSC8Rsc8p0.998
RSC4Rsc4p0.992
RSC2Rsc2p0.991
ARP7Arp7p0.974
STH1Sth1p0.969
RSC3Rsc3p0.953
RSC6Rsc6p0.935
RSC9Rsc9p0.909
HHF1Hhf1p0.875
NPL6Npl6p0.812
ARP9Arp9p0.769
RSC1Rsc1p0.638
HHF2Hhf2p0.555
RTT102Rtt102p0.553
RSC58Rsc58p0.507
HHT2Hht2p0.289
HTL1Htl1p0.289
SWI1Swi1p0.236
RSC30Rsc30p0.129
SFH1Sfh1p0.108
BDF1Bdf1p0.074
SWI3Swi3p0.066
TRA1Tra1p0.064
HHT1Hht1p0.034
SPT10Spt10p0.033
REB1Reb1p0.032
NHP6ANhp6ap0.029
SPT20Spt20p0.027
BDF2Bdf2p0.024
CRP1Crp1p0.020
PCL9Pcl9p0.018
SRD1Srd1p0.017
POB3Pob3p0.016
PTI1Pti1p0.016
EAF1Eaf1p0.015
LEU2Leu2p0.015
SNF11Snf11p0.014
YOL038C-Ahypothetical protein0.014
LEO1Leo1p0.013
YLR264C-Ahypothetical protein0.013
YLR162Whypothetical protein0.013
MER1Mer1p0.013
ARP10Arp10p0.013
HXT3Hxt3p0.013
CUP1-1Cup1-1p0.012
TAF7Taf7p0.011
ATP6Atp6p0.011
HHO1Hho1p0.011
IXR1Ixr1p0.011
CHA1Cha1p0.011
SWC7Swc7p0.011
YAR068Whypothetical protein0.011
YPR157Whypothetical protein0.011
YLR042Chypothetical protein0.011
SPL2Spl2p0.010
RTT106Rtt106p0.010
ZPS1Zps1p0.010
YBR013Chypothetical protein0.010