The network for 'regulation of organ growth' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of organ growth

Any process that modulates the frequency, rate or extent of growth of an organ of an organism.

NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 21.000
Shhsonic hedgehog0.998
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.993
Apcadenomatosis polyposis coli0.988
Gli3GLI-Kruppel family member GLI30.981
Tbx3T-box 30.979
Gata4GATA binding protein 40.969
Pax2paired box gene 20.967
Ptenphosphatase and tensin homolog0.952
Ctnnb1catenin (cadherin associated protein), beta 10.935
Lef1lymphoid enhancer binding factor 10.924
Fgf10fibroblast growth factor 100.904
Pax8paired box gene 80.878
Itgb1integrin beta 1 (fibronectin receptor beta)0.845
Fgf8fibroblast growth factor 80.827
Bmp4bone morphogenetic protein 40.812
Gli2GLI-Kruppel family member GLI20.793
Nkx2-1NK2 homeobox 10.776
Zfpm2zinc finger protein, multitype 20.773
Pax3paired box gene 30.721
Hoxa1homeobox A10.716
Ntf3neurotrophin 30.686
Foxc1forkhead box C10.686
Foxc2forkhead box C20.679
Hand2heart and neural crest derivatives expressed transcript 20.675
Vegfavascular endothelial growth factor A0.675
Tbx5T-box 50.662
Pitx2paired-like homeodomain transcription factor 20.628
Lhx1LIM homeobox protein 10.617
Trp63transformation related protein 630.612
Sox2SRY-box containing gene 20.611
Fgfr1fibroblast growth factor receptor 10.593
Notch1Notch gene homolog 1 (Drosophila)0.578
Otx2orthodenticle homolog 2 (Drosophila)0.565
Wnt3awingless-related MMTV integration site 3A0.541
Wt1Wilms tumor 1 homolog0.518
Lmx1aLIM homeobox transcription factor 1 alpha0.517
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.507
Hoxa13homeobox A130.489
Ror2receptor tyrosine kinase-like orphan receptor 20.484
Alx3aristaless-like homeobox 30.482
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.459
Foxa2forkhead box A20.438
Bcl2B-cell leukemia/lymphoma 20.427
Trp53transformation related protein 530.411
Wnt6wingless-related MMTV integration site 60.411
Nf1neurofibromatosis 10.410
Ptpn11protein tyrosine phosphatase, non-receptor type 110.401
Emx1empty spiracles homolog 1 (Drosophila)0.397
Yap1yes-associated protein 10.392
Tbx1T-box 10.379
Tcf21transcription factor 210.371
Emx2empty spiracles homolog 2 (Drosophila)0.364
Hand1heart and neural crest derivatives expressed transcript 10.361
Alx4aristaless-like homeobox 40.357
Fzd4frizzled homolog 4 (Drosophila)0.354
Tbx15T-box 150.344
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.341
Drd2dopamine receptor D20.336
Nr5a1nuclear receptor subfamily 5, group A, member 10.332
Twist2twist homolog 2 (Drosophila)0.325
Rxraretinoid X receptor alpha0.323
Cdx2caudal type homeobox 20.323
Gata6GATA binding protein 60.322
Efnb2ephrin B20.299
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.295
Tbx2T-box 20.295
Foxf1aforkhead box F1a0.292
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.292
Sox9SRY-box containing gene 90.287
Smad6MAD homolog 6 (Drosophila)0.285
Jag1jagged 10.283
FosFBJ osteosarcoma oncogene0.283
Onecut1one cut domain, family member 10.282
Bmpr1abone morphogenetic protein receptor, type 1A0.266
Gata5GATA binding protein 50.264
Gdnfglial cell line derived neurotrophic factor0.263
Tal1T-cell acute lymphocytic leukemia 10.261
Pou3f1POU domain, class 3, transcription factor 10.252
Emid2EMI domain containing 20.251
Pou3f3POU domain, class 3, transcription factor 30.242
Bcl6B-cell leukemia/lymphoma 60.240
Gli1GLI-Kruppel family member GLI10.237
Foxf2forkhead box F20.237
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.232
Dlx5distal-less homeobox 50.230
Igf1rinsulin-like growth factor I receptor0.229
Foxb1forkhead box B10.229
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.225
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.220
Wnt10bwingless related MMTV integration site 10b0.218
Lhx3LIM homeobox protein 30.208
Bdkrb2bradykinin receptor, beta 20.207
Pou5f1POU domain, class 5, transcription factor 10.205
Fgf15fibroblast growth factor 150.205
Pax9paired box gene 90.197
Flt4FMS-like tyrosine kinase 40.196
Tead1TEA domain family member 10.195
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-15Protein EGL-150.280
sel-8Protein SEL-80.276
bar-1Protein BAR-10.173
R05G6.10Protein R05G6.100.140
sma-6Protein SMA-60.093
egl-36Protein EGL-360.077
cst-1Protein CST-10.066
sma-10Protein SMA-100.059
exc-5Protein EXC-50.043
pry-1Protein PRY-10.039
daf-21Protein DAF-210.039
F10G8.8Protein F10G8.80.037
camt-1Protein CAMT-10.030
cst-2Protein CST-20.027
sos-1Protein SOS-10.027
unc-53Protein UNC-530.025
let-60Protein LET-600.023
egl-30Protein EGL-300.023
lrp-2Protein LRP-20.022
spc-1Protein SPC-10.021
C53C9.2Protein C53C9.20.020
axl-1Protein AXL-10.019
unc-45Protein UNC-450.019
frm-7Protein FRM-70.019
egl-38Protein EGL-380.019
egl-23Protein EGL-230.017
mes-3Protein MES-30.017
tag-241Protein TAG-2410.017
daz-1Protein DAZ-10.016
plc-1Protein PLC-10.016
fmi-1Protein FMI-10.015
glp-1Protein GLP-10.015
Y42G9A.3Protein Y42G9A.30.014
plc-3Protein PLC-30.014
magu-2Protein MAGU-20.013
cpna-1Protein CPNA-10.012
gmeb-1Protein GMEB-10.012
uri-1Protein URI-10.012
pde-4Protein PDE-40.012
cpna-5Protein CPNA-50.011
bag-1Protein BAG-10.011
F46F11.6Protein F46F11.60.011
sem-5Protein SEM-50.011
lin-7Protein LIN-70.011
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.986
fgfr1afibroblast growth factor receptor 1a0.897
tp73tumor protein p730.810
lhx2bLIM homeobox 2b0.806
gli1GLI-Kruppel family member 10.737
wt1awilms tumor 1a0.696
mecomMDS1 and EVI1 complex locus0.657
hspa12bheat shock protein 12B0.541
ihhaIndian hedgehog homolog a0.524
sema3aasemaphorin 3aa0.519
jag1bjagged 1b0.511
igf1rbinsulin-like growth factor 1b receptor0.499
smyhc1slow myosin heavy chain 10.464
bmp2bbone morphogenetic protein 2b0.462
prox1prospero-related homeobox gene 10.403
rspo3R-spondin 3 homolog (Xenopus laevis)0.383
tp53bp2tumor protein p53 binding protein, 20.382
ahi1Abelson helper integration site 10.370
gdnfglial cell derived neurotrophic factor0.368
efnb2aephrin B2a0.343
tnni1altroponin I, skeletal, slow like0.342
zbtb4zinc finger and BTB domain containing 40.333
bmp4bone morphogenetic protein 40.333
hey2hairy/enhancer-of-split related with YRPW motif 20.314
lmx1b.1LIM homeobox transcription factor 1, beta 10.313
has2hyaluronan synthase 20.295
ldb2aLIM-domain binding factor 2a0.287
plcg1phospholipase C, gamma 10.278
emx3empty spiracles homeobox 30.269
pitx3paired-like homeodomain transcription factor 30.266
tnnc1btroponin C type 1b (slow)0.259
notch3notch homolog 30.258
lhx3LIM homeobox 30.258
mibmind bomb0.257
cyp11b2cytochrome P450, family 11, subfamily B, polypeptide 20.256
ttnatitin a0.250
sox9aSRY-box containing gene 9a0.247
ptch1patched 10.236
smg7Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)0.227
rbfox1lRNA binding protein, fox-1 homolog (C. elegans) 1-like0.226
hnf1baHNF1 homeobox Ba0.226
etv2ets variant gene 20.212
emx1empty spiracles homeobox 10.211
mef2cbmyocyte enhancer factor 2cb0.208
pld1aphospholipase D1a0.205
ankrd6ankyrin repeat domain 60.203
notch1bnotch homolog 1b0.202
aldh1a2aldehyde dehydrogenase 1 family, member A20.201
gro1groucho 10.191
wlswntless homolog (Drosophila)0.190
notch2notch homolog 20.187
foxc1aforkhead box C1a0.184
mef2camyocyte enhancer factor 2ca0.179
unc5bunc-5 homolog B (C. elegans)0.177
foxa3forkhead box A30.176
wnt2bawingless-type MMTV integration site family, member 2Ba0.176
wnt2bbwingless-type MMTV integration site family, member 2Bb0.173
gja3gap junction protein, alpha 30.159
kif23kinesin family member 230.154
tbx5aT-box 5a0.151
ralgapa1Ral GTPase activating protein, alpha subunit 1 (catalytic)0.149
trpm7transient receptor potential cation channel, subfamily M, member 70.148
pdlim7PDZ and LIM domain 70.147
fgfrl1afibroblast growth factor receptor-like 1a0.147
h1mlinker histone H1M0.144
fzd7bfrizzled homolog 7b0.144
gata4GATA-binding protein 40.138
gro2groucho 20.137
ncoa2nuclear receptor coactivator 20.136
nkx2.5NK2 transcription factor related 50.135
kcnh2potassium voltage-gated channel, subfamily H (eag-related), member 20.133
ripk2receptor-interacting serine-threonine kinase 20.131
nog2noggin 20.129
clec14aC-type lectin domain family 14, member A0.129
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.127
amotl2aangiomotin like 2a0.124
sox9bSRY-box containing gene 9b0.123
adrb2aadrenergic receptor, beta 2a0.122
tbx18T-box 180.121
dll4delta-like 4 (Drosophila)0.121
myod1myogenic differentiation 10.120
foxi1forkhead box I10.120
nrg2aneuregulin 2a0.119
tll1tolloid-like 10.119
tbx20T-box 200.117
tp53tumor protein p530.117
tjp1tight junction protein 1 (zona occludens 1)0.114
fgf3fibroblast growth factor 30.114
emp2epithelial membrane protein 20.112
bocbrother of CDO0.112
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.111
dccdeleted in colorectal carcinoma0.111
angpt1angiopoietin 10.111
limk2LIM domain kinase 20.110
cyp24a1cytochrome P450, family 24, subfamily A, polypeptide 10.109
dmrt2adoublesex and mab-3 related transcription factor 2a0.107
fstafollistatin a0.107
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
MadMothers against dpp0.958
Pi3K92ECG4141 gene product from transcript CG4141-RB0.726
Ilp2Insulin-like peptide 20.504
S6kRPS6-p70-protein kinase0.502
dcodiscs overgrown0.484
Ilp5Insulin-like peptide 50.306
Tao-1CG14217 gene product from transcript CG14217-RF0.274
RhebCG1081 gene product from transcript CG1081-RA0.273
InRInsulin-like receptor0.245
Akt1CG4006 gene product from transcript CG4006-RA0.241
Vap-33-1CG5014 gene product from transcript CG5014-RB0.216
Ten-mTenascin major0.209
Ilp3Insulin-like peptide 30.200
Tsc1CG6147 gene product from transcript CG6147-RA0.197
Snr1Snf5-related 10.180
sNPF-Rshort neuropeptide F receptor0.170
CycECyclin E0.169
cicubitus interruptus0.160
grimCG4345 gene product from transcript CG4345-RA0.139
CG31352CG31352 gene product from transcript CG31352-RA0.126
WnkCG7177 gene product from transcript CG7177-RA0.109
aopanterior open0.102
chicoCG5686 gene product from transcript CG5686-RB0.101
jebjelly belly0.097
CG17658CG17658 gene product from transcript CG17658-RA0.095
TorTarget of rapamycin0.093
Pde1cPhosphodiesterase 1c0.093
picoCG11940 gene product from transcript CG11940-RA0.086
Stat92ESignal-transducer and activator of transcription protein at 92E0.081
Pp2B-14DProtein phosphatase 2B at 14D0.080
sosine oculis0.080
cindrCIN85 and CD2AP orthologue0.079
stumpsCG31317 gene product from transcript CG31317-RC0.076
Ilp6Insulin-like peptide 60.075
DrefDNA replication-related element factor0.075
RbfRetinoblastoma-family protein0.072
kirrekin of irre0.071
BHDBirt-Hogg-Dube homolog0.066
witwishful thinking0.061
Top1Topoisomerase 10.060
slikSterile20-like kinase0.054
DadDaughters against dpp0.050
Mlc2Myosin light chain 20.047
Nf1Neurofibromin 10.046
Fas2Fasciclin 20.045
Eip93FCG18389 gene product from transcript CG18389-RB0.045
CG11093CG11093 gene product from transcript CG11093-RB0.045
mewmultiple edematous wings0.044
dlg1discs large 10.044
snssticks and stones0.043
B4CG9239 gene product from transcript CG9239-RA0.043
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FGFR2fibroblast growth factor receptor 20.987
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.811
INSRinsulin receptor0.721
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.434
FGFR1fibroblast growth factor receptor 10.374
FGF1fibroblast growth factor 1 (acidic)0.279
GRB10growth factor receptor-bound protein 100.231
FGF10fibroblast growth factor 100.202
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.161
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.157
TP53tumor protein p530.133
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.121
HDAC1histone deacetylase 10.099
EP300E1A binding protein p3000.065
HDAC4histone deacetylase 40.065
NCOR1nuclear receptor corepressor 10.062
IRS1insulin receptor substrate 10.060
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.058
JAG1jagged 10.055
SCHIP1schwannomin interacting protein 10.048
PPARAperoxisome proliferator-activated receptor alpha0.048
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.042
YY1YY1 transcription factor0.039
TBX5T-box 50.038
EGFRepidermal growth factor receptor0.031
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.031
GATA4GATA binding protein 40.026
IGF1Rinsulin-like growth factor 1 receptor0.026
LATS1LATS, large tumor suppressor, homolog 1 (Drosophila)0.024
WDR5WD repeat domain 50.024
CREBBPCREB binding protein0.024
MOBKL1AMOB1, Mps One Binder kinase activator-like 1A (yeast)0.022
YAP1Yes-associated protein 10.022
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.021
FGF2fibroblast growth factor 2 (basic)0.019
NOTCH1notch 10.019
NEDD4neural precursor cell expressed, developmentally down-regulated 40.019
STK4serine/threonine kinase 40.019
TNRC6Btrinucleotide repeat containing 6B0.019
BADBCL2-associated agonist of cell death0.018
PTPN14protein tyrosine phosphatase, non-receptor type 140.018
RASSF5Ras association (RalGDS/AF-6) domain family member 50.018
SMAD3SMAD family member 30.017
CSNK1Ecasein kinase 1, epsilon0.016
IRS2insulin receptor substrate 20.016
ATXN1Lataxin 1-like0.016
CABLES1Cdk5 and Abl enzyme substrate 10.015
RASSF1Ras association (RalGDS/AF-6) domain family member 10.015
STK3serine/threonine kinase 30.015
TCF12transcription factor 120.015
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.015
HIC1hypermethylated in cancer 10.014
AXIN1axin 10.014
PRKCZprotein kinase C, zeta0.014
RASSF3Ras association (RalGDS/AF-6) domain family member 30.014
RUVBL1RuvB-like 1 (E. coli)0.013
ARandrogen receptor0.013
RARAretinoic acid receptor, alpha0.013
CCNE1cyclin E10.012
MYST3MYST histone acetyltransferase (monocytic leukemia) 30.012
DVL3dishevelled, dsh homolog 3 (Drosophila)0.012
HIPK3homeodomain interacting protein kinase 30.012
SAV1salvador homolog 1 (Drosophila)0.012
FGF7fibroblast growth factor 70.011
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.011
SNAI1snail homolog 1 (Drosophila)0.011
ESR1estrogen receptor 10.011
WT1Wilms tumor 10.011
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
LOC100362824caveolin 2-like0.188
Nos3nitric oxide synthase 3, endothelial cell0.164
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.095
Smad7SMAD family member 70.088
Nedd4neural precursor cell expressed, developmentally down-regulated 40.080
Eef2eukaryotic translation elongation factor 20.079
Cdkn3cyclin-dependent kinase inhibitor 30.075
Syt8synaptotagmin VIII0.067
Myo1cmyosin IC0.065
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.057
Phkg1phosphorylase kinase, gamma 10.056
Gja3gap junction protein, alpha 30.053
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.052
Nek9NIMA (never in mitosis gene a)- related kinase 90.049
Notch2Notch homolog 2 (Drosophila)0.048
Top2atopoisomerase (DNA) II alpha0.047
Fgfr2fibroblast growth factor receptor 20.045
Oprd1opioid receptor, delta 10.043
Timp3TIMP metallopeptidase inhibitor 30.041
Egr1early growth response 10.039
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.039
Muskmuscle, skeletal, receptor tyrosine kinase0.039
Kcng2potassium voltage-gated channel, subfamily G, member 20.039
Strnstriatin, calmodulin binding protein0.037
Prrx1paired related homeobox 10.037
Ube2cubiquitin-conjugating enzyme E2C0.036
Arhgap23Rho GTPase activating protein 230.034
Tpc1808tropic 18080.034
Usf2upstream transcription factor 2, c-fos interacting0.033
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.033
Kalrnkalirin, RhoGEF kinase0.033
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.032
Gata6GATA binding protein 60.032
Cks2CDC28 protein kinase regulatory subunit 20.031
Adra2cadrenergic, alpha-2C-, receptor0.031
Fgf16fibroblast growth factor 160.031
Il7interleukin 70.031
Hspb2heat shock protein beta 20.031
Prl8a2prolactin family 8, subfamily a, member 20.030
Nfibnuclear factor I/B0.030
Prp15proline-rich protein 150.030
Gna12guanine nucleotide binding protein (G protein) alpha 120.029
Ccnd3cyclin D30.028
Cckbrcholecystokinin B receptor0.026
Cdca3cell division cycle associated 30.025
Olfml2bolfactomedin-like 2B0.025
Tgfbr2transforming growth factor, beta receptor II0.024
Traf4af1TRAF4 associated factor 10.023
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.023
Hoxc4homeo box C40.023
Ompolfactory marker protein0.022
Slc1a6solute carrier family 1 (high affinity aspartate/glutamate transporter), member 60.022
Metmet proto-oncogene0.022
Gabrg3gamma-aminobutyric acid (GABA) A receptor, gamma 30.022
Prkcaprotein kinase C, alpha0.021
Pgam2phosphoglycerate mutase 2 (muscle)0.021
Olr287olfactory receptor 2870.020
KitlgKIT ligand0.020
Fgf14fibroblast growth factor 140.020
Dnah9dynein, axonemal, heavy polypeptide 90.020
Avparginine vasopressin0.020
Lim2lens intrinsic membrane protein 20.019
Gja4gap junction protein, alpha 40.019
Myo1bmyosin Ib0.019
Stat6signal transducer and activator of transcription 60.019
Vdrvitamin D (1,25- dihydroxyvitamin D3) receptor0.018
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.018
Rgs14regulator of G-protein signaling 140.018
Mpripmyosin phosphatase Rho interacting protein0.018
Emp1epithelial membrane protein 10.018
Acvr1cactivin A receptor, type IC0.018
Il11interleukin 110.018
Tcf12transcription factor 120.017
Slc2a13solute carrier family 2 (facilitated glucose transporter), member 130.017
Nrg1neuregulin 10.017
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)0.017
Vom1r101vomeronasal 1 receptor 1010.016
Pecam1platelet/endothelial cell adhesion molecule 10.016
Kcnj16potassium inwardly-rectifying channel, subfamily J, member 160.016
Cxcr4chemokine (C-X-C motif) receptor 40.016
Htr2a5-hydroxytryptamine (serotonin) receptor 2A0.016
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.016
RGD1564664similar to LOC387763 protein0.016
Dsppdentin sialophosphoprotein0.016
Dlg4discs, large homolog 4 (Drosophila)0.016
Igfbp5insulin-like growth factor binding protein 50.016
Glg1golgi apparatus protein 10.016
Cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.015
Birc5baculoviral IAP repeat-containing 50.015
Lims1LIM and senescent cell antigen-like domains 10.015
Ednraendothelin receptor type A0.015
Ghrgrowth hormone receptor0.015
Pitx1paired-like homeodomain 10.015
Akt2v-akt murine thymoma viral oncogene homolog 20.015
Syngr2synaptogyrin 20.015
Vom2r27vomeronasal 2 receptor, 270.015
Sp1Sp1 transcription factor0.015
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism