The network for 'regulation of mitochondrial membrane potential' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of mitochondrial membrane potential

Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.

NameDescriptionProbabilityFunc Analog Organism
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.999
Gclmglutamate-cysteine ligase, modifier subunit0.515
Gbp5guanylate binding protein 50.451
Gclcglutamate-cysteine ligase, catalytic subunit0.426
Pmaip1phorbol-12-myristate-13-acetate-induced protein 10.364
Casp1caspase 10.355
Trp53transformation related protein 530.348
Casp4caspase 4, apoptosis-related cysteine peptidase0.288
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.243
Il18interleukin 180.210
Mcl1myeloid cell leukemia sequence 10.206
Bcl2B-cell leukemia/lymphoma 20.154
Gsk3bglycogen synthase kinase 3 beta0.130
PycardPYD and CARD domain containing0.103
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.086
SrcRous sarcoma oncogene0.082
Tlr4toll-like receptor 40.080
BaxBCL2-associated X protein0.080
BidBH3 interacting domain death agonist0.073
Ptk2PTK2 protein tyrosine kinase 20.073
Hspd1heat shock protein 1 (chaperonin)0.067
Cdk4cyclin-dependent kinase 40.062
Retret proto-oncogene0.061
Hif1ahypoxia inducible factor 1, alpha subunit0.057
Psmb2proteasome (prosome, macropain) subunit, beta type 20.057
Pxnpaxillin0.050
FaddFas (TNFRSF6)-associated via death domain0.045
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.039
Lystlysosomal trafficking regulator0.038
Ripk3receptor-interacting serine-threonine kinase 30.037
Casp3caspase 30.037
Egr3early growth response 30.036
Actbactin, beta0.036
Gfm1G elongation factor, mitochondrial 10.032
Mfn2mitofusin 20.032
Nfe2l2nuclear factor, erythroid derived 2, like 20.031
MaxMax protein0.031
Aqp7aquaporin 70.029
Gcshglycine cleavage system protein H (aminomethyl carrier)0.029
Timm23translocase of inner mitochondrial membrane 23 homolog (yeast)0.028
Cntnap1contactin associated protein-like 10.027
Il2rbinterleukin 2 receptor, beta chain0.025
Stx1asyntaxin 1A (brain)0.024
Notch2Notch gene homolog 2 (Drosophila)0.024
P2rx3purinergic receptor P2X, ligand-gated ion channel, 30.024
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.022
NmiN-myc (and STAT) interactor0.022
Btrcbeta-transducin repeat containing protein0.022
Mobkl1bMOB1, Mps One Binder kinase activator-like 1B (yeast)0.022
Rbl1retinoblastoma-like 1 (p107)0.021
Sox10SRY-box containing gene 100.021
Tnfsf10tumor necrosis factor (ligand) superfamily, member 100.021
Prkar2bprotein kinase, cAMP dependent regulatory, type II beta0.021
Casp7caspase 70.021
Smad3MAD homolog 3 (Drosophila)0.020
Mrps28mitochondrial ribosomal protein S280.020
Nraddneurotrophin receptor associated death domain0.020
Galgalanin0.020
Aifm1apoptosis-inducing factor, mitochondrion-associated 10.019
Vhlvon Hippel-Lindau tumor suppressor0.019
RestRE1-silencing transcription factor0.019
Itgb1integrin beta 1 (fibronectin receptor beta)0.019
Pip5k1bphosphatidylinositol-4-phosphate 5-kinase, type 1 beta0.019
Slc6a4solute carrier family 6 (neurotransmitter transporter, serotonin), member 40.019
Ptgirprostaglandin I receptor (IP)0.019
Psmb3proteasome (prosome, macropain) subunit, beta type 30.019
Abcb9ATP-binding cassette, sub-family B (MDR/TAP), member 90.018
Rps3ribosomal protein S30.018
LitafLPS-induced TN factor0.018
Agrpagouti related protein0.018
Bcl2l1BCL2-like 10.018
Il1r1interleukin 1 receptor, type I0.018
Cops6COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)0.018
Kitkit oncogene0.018
Ryr1ryanodine receptor 1, skeletal muscle0.017
Coq7demethyl-Q 70.017
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.017
Apaf1apoptotic peptidase activating factor 10.017
Irf4interferon regulatory factor 40.016
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.016
Dnaja3DnaJ (Hsp40) homolog, subfamily A, member 30.015
Msnmoesin0.015
Prkceprotein kinase C, epsilon0.015
Timm8a1translocase of inner mitochondrial membrane 8 homolog a1 (yeast)0.015
Ccl1chemokine (C-C motif) ligand 10.015
Snap25synaptosomal-associated protein 250.015
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.014
Tgif1TGFB-induced factor homeobox 10.014
Hif1anhypoxia-inducible factor 1, alpha subunit inhibitor0.014
Wlswntless homolog (Drosophila)0.014
Ctnnd1catenin (cadherin associated protein), delta 10.013
Il1binterleukin 1 beta0.013
Cd44CD44 antigen0.013
Ikzf3IKAROS family zinc finger 30.013
Fh1fumarate hydratase 10.013
Vimvimentin0.013
Tax1bp3Tax1 (human T-cell leukemia virus type I) binding protein 30.013
Timm17atranslocase of inner mitochondrial membrane 17a0.013
Mrpl16mitochondrial ribosomal protein L160.012
Gbp7guanylate binding protein 70.012
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Sod2Superoxide dismutase 2 (Mn)0.067
parkparkin0.035
Pink1PTEN-induced putative kinase 10.024
SdhBSuccinate dehydrogenase B0.022
porinCG6647 gene product from transcript CG6647-RA0.018
CatCatalase0.017
borbelphegor0.014
dj-1betaCG1349 gene product from transcript CG1349-RA0.014
imdimmune deficiency0.013
BG4CG12297 gene product from transcript CG12297-RA0.012
DJ-1alphaCG6646 gene product from transcript CG6646-RA0.012
molmoladietz0.011
CG5214CG5214 gene product from transcript CG5214-RA0.011
CG8443CG8443 gene product from transcript CG8443-RA0.011
Ppat-DpckBifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BCL2L1BCL2-like 10.935
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.831
BCL2B-cell CLL/lymphoma 20.736
BCL2L11BCL2-like 11 (apoptosis facilitator)0.700
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.629
PRDX4peroxiredoxin 40.603
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.458
DRD2dopamine receptor D20.453
HCKhemopoietic cell kinase0.432
PRDX1peroxiredoxin 10.427
TXNthioredoxin0.380
SYKspleen tyrosine kinase0.364
BADBCL2-associated agonist of cell death0.353
GRB2growth factor receptor-bound protein 20.272
VDAC1voltage-dependent anion channel 10.260
GCLMglutamate-cysteine ligase, modifier subunit0.229
LCKlymphocyte-specific protein tyrosine kinase0.228
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.219
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.211
GCLCglutamate-cysteine ligase, catalytic subunit0.208
HSPA8heat shock 70kDa protein 80.200
BLNKB-cell linker0.185
PDCD6programmed cell death 60.165
SOD1superoxide dismutase 1, soluble0.161
BAK1BCL2-antagonist/killer 10.153
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.147
PRDX3peroxiredoxin 30.138
NLRC4NLR family, CARD domain containing 40.128
FYNFYN oncogene related to SRC, FGR, YES0.118
MPDZmultiple PDZ domain protein0.114
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.111
NAMPTnicotinamide phosphoribosyltransferase0.108
NCK1NCK adaptor protein 10.101
BAXBCL2-associated X protein0.098
FADDFas (TNFRSF6)-associated via death domain0.092
FBXO7F-box protein 70.081
WIPF1WAS/WASL interacting protein family, member 10.063
PMAIP1phorbol-12-myristate-13-acetate-induced protein 10.062
IFITM3interferon induced transmembrane protein 3 (1-8U)0.060
SH3KBP1SH3-domain kinase binding protein 10.060
BIDBH3 interacting domain death agonist0.058
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.055
EIF6eukaryotic translation initiation factor 60.054
HSPD1heat shock 60kDa protein 1 (chaperonin)0.047
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.046
SPRR2Asmall proline-rich protein 2A0.042
LRP6low density lipoprotein receptor-related protein 60.042
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.040
LGALS1lectin, galactoside-binding, soluble, 10.039
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.038
CD320CD320 molecule0.038
GAS7growth arrest-specific 70.037
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.037
SDHBsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.037
AHSA1AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)0.037
NECAB2N-terminal EF-hand calcium binding protein 20.036
CD2APCD2-associated protein0.034
UBASH3Bubiquitin associated and SH3 domain containing B0.033
RNF144Bring finger protein 144B0.033
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.033
DAZAP2DAZ associated protein 20.032
PRDX2peroxiredoxin 20.032
PRDX6peroxiredoxin 60.032
RIPK2receptor-interacting serine-threonine kinase 20.032
PTGES3prostaglandin E synthase 3 (cytosolic)0.031
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.031
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.031
PPIDpeptidylprolyl isomerase D0.030
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.030
ITKIL2-inducible T-cell kinase0.030
RAB5BRAB5B, member RAS oncogene family0.030
OPTNoptineurin0.028
IFI44interferon-induced protein 440.028
STMN2stathmin-like 20.028
CALM1calmodulin 1 (phosphorylase kinase, delta)0.027
MDH1malate dehydrogenase 1, NAD (soluble)0.027
PDHXpyruvate dehydrogenase complex, component X0.027
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)0.026
TBXA2Rthromboxane A2 receptor0.026
PYCARDPYD and CARD domain containing0.026
SERPINB1serpin peptidase inhibitor, clade B (ovalbumin), member 10.025
RNF11ring finger protein 110.025
DAPK1death-associated protein kinase 10.025
DBN1drebrin 10.024
CASP4caspase 4, apoptosis-related cysteine peptidase0.024
SQSTM1sequestosome 10.024
IFI27interferon, alpha-inducible protein 270.024
PTENphosphatase and tensin homolog0.024
ZFYVE9zinc finger, FYVE domain containing 90.023
SSTR2somatostatin receptor 20.023
DLDdihydrolipoamide dehydrogenase0.023
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.023
DUSP23dual specificity phosphatase 230.022
FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.022
GABARAPL2GABA(A) receptor-associated protein-like 20.022
VAV1vav 1 guanine nucleotide exchange factor0.022
IFI44Linterferon-induced protein 44-like0.021
RPL10ribosomal protein L100.020
BTKBruton agammaglobulinemia tyrosine kinase0.019
RNR2l-rRNA0.019
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
UBI4Ubi4p0.096
RRP4Rrp4p0.012
PWP2Pwp2p0.010