The network for 'activation of nf kappab inducing kinase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

activation of nf kappab inducing kinase activity

The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.

NameDescriptionProbabilityFunc Analog Organism
Map3k7mitogen-activated protein kinase kinase kinase 71.000
Traf6TNF receptor-associated factor 61.000
Ikbkginhibitor of kappaB kinase gamma1.000
Ikbkbinhibitor of kappaB kinase beta1.000
Chukconserved helix-loop-helix ubiquitous kinase0.929
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.926
Tab2TGF-beta activated kinase 1/MAP3K7 binding protein 20.919
Tnfaip3tumor necrosis factor, alpha-induced protein 30.910
Myd88myeloid differentiation primary response gene 880.895
Hspa1bheat shock protein 1B0.838
Umoduromodulin0.711
Agtr1aangiotensin II receptor, type 1a0.559
Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 10.491
Irak3interleukin-1 receptor-associated kinase 30.469
Rnf31ring finger protein 310.378
Serpina1bserine (or cysteine) preptidase inhibitor, clade A, member 1B0.346
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.337
Smad1MAD homolog 1 (Drosophila)0.286
Ren1renin 1 structural0.273
Nr0b2nuclear receptor subfamily 0, group B, member 20.253
TifaTRAF-interacting protein with forkhead-associated domain0.253
Gps1G protein pathway suppressor 10.238
Tab1TGF-beta activated kinase 1/MAP3K7 binding protein 10.222
Cd40CD40 antigen0.219
SkilSKI-like0.182
Ube2nubiquitin-conjugating enzyme E2N0.171
Trafd1TRAF type zinc finger domain containing 10.170
Irak1interleukin-1 receptor-associated kinase 10.167
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.167
Serpina3cserine (or cysteine) peptidase inhibitor, clade A, member 3C0.166
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.139
Lrg1leucine-rich alpha-2-glycoprotein 10.137
Itchitchy, E3 ubiquitin protein ligase0.134
Traf3ip2TRAF3 interacting protein 20.109
Birc3baculoviral IAP repeat-containing 30.109
Serpina1aserine (or cysteine) peptidase inhibitor, clade A, member 1A0.097
C4bcomplement component 4B (Childo blood group)0.094
Serpina3mserine (or cysteine) peptidase inhibitor, clade A, member 3M0.092
Hphaptoglobin0.089
Map3k1mitogen-activated protein kinase kinase kinase 10.087
Agtr2angiotensin II receptor, type 20.085
Lbplipopolysaccharide binding protein0.084
Abcb4ATP-binding cassette, sub-family B (MDR/TAP), member 40.079
Itih3inter-alpha trypsin inhibitor, heavy chain 30.078
EcsitECSIT homolog (Drosophila)0.074
Ltbrlymphotoxin B receptor0.074
Peli2pellino 20.072
Tmprss11etransmembrane protease, serine 11e0.067
Cpceruloplasmin0.065
Cyldcylindromatosis (turban tumor syndrome)0.064
Ahraryl-hydrocarbon receptor0.063
F9coagulation factor IX0.060
Zmpste24zinc metallopeptidase, STE24 homolog (S. cerevisiae)0.057
Map2k4mitogen-activated protein kinase kinase 40.056
Ighimmunoglobulin heavy chain complex0.054
Gm11567predicted gene 115670.053
Edarectodysplasin-A receptor0.053
Itih4inter alpha-trypsin inhibitor, heavy chain 40.051
Card11caspase recruitment domain family, member 110.051
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.050
Malt1mucosa associated lymphoid tissue lymphoma translocation gene 10.049
Stat3signal transducer and activator of transcription 30.049
Serpina1cserine (or cysteine) peptidase inhibitor, clade A, member 1C0.047
Apoc4apolipoprotein C-IV0.046
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.045
Cyp2c50cytochrome P450, family 2, subfamily c, polypeptide 500.043
Hmgcs23-hydroxy-3-methylglutaryl-Coenzyme A synthase 20.041
Albalbumin0.041
Map3k3mitogen-activated protein kinase kinase kinase 30.041
Serping1serine (or cysteine) peptidase inhibitor, clade G, member 10.040
Ripk2receptor (TNFRSF)-interacting serine-threonine kinase 20.040
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.040
SharpinSHANK-associated RH domain interacting protein0.040
Il1r1interleukin 1 receptor, type I0.039
Apofapolipoprotein F0.039
Ahsgalpha-2-HS-glycoprotein0.038
Hspa1aheat shock protein 1A0.038
Edaectodysplasin-A0.038
Steap4STEAP family member 40.037
Traf2TNF receptor-associated factor 20.037
Elnelastin0.036
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.036
Bcl6B-cell leukemia/lymphoma 60.034
Bcl10B-cell leukemia/lymphoma 100.033
Lcn2lipocalin 20.033
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.032
Baatbile acid-Coenzyme A: amino acid N-acyltransferase0.032
Slc12a1solute carrier family 12, member 10.031
Smad5MAD homolog 5 (Drosophila)0.031
Leprleptin receptor0.031
Jag1jagged 10.031
Kng1kininogen 10.030
Cyp2c38cytochrome P450, family 2, subfamily c, polypeptide 380.030
C3complement component 30.030
Adh4alcohol dehydrogenase 4 (class II), pi polypeptide0.028
F10coagulation factor X0.027
Tdo2tryptophan 2,3-dioxygenase0.027
Id2inhibitor of DNA binding 20.027
Pi16peptidase inhibitor 160.027
Trp53transformation related protein 530.026
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TRAF6TNF receptor-associated factor 61.000
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.992
MAP3K14mitogen-activated protein kinase kinase kinase 140.992
IRAK2interleukin-1 receptor-associated kinase 20.958
BCL10B-cell CLL/lymphoma 100.938
CASP8caspase 8, apoptosis-related cysteine peptidase0.910
TRAF3TNF receptor-associated factor 30.908
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.848
TRAF2TNF receptor-associated factor 20.838
CFLARCASP8 and FADD-like apoptosis regulator0.782
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.756
IRAK1interleukin-1 receptor-associated kinase 10.751
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.735
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.693
TNFRSF6Btumor necrosis factor receptor superfamily, member 6b, decoy0.608
BIRC3baculoviral IAP repeat containing 30.585
TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)0.569
SQSTM1sequestosome 10.564
CD40CD40 molecule, TNF receptor superfamily member 50.564
PELI3pellino homolog 3 (Drosophila)0.506
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.450
TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 20.317
RIPK2receptor-interacting serine-threonine kinase 20.268
CASP10caspase 10, apoptosis-related cysteine peptidase0.266
GFERgrowth factor, augmenter of liver regeneration0.261
TAB3TGF-beta activated kinase 1/MAP3K7 binding protein 30.244
TNFAIP3tumor necrosis factor, alpha-induced protein 30.215
NUMBLnumb homolog (Drosophila)-like0.212
ZNF512Bzinc finger protein 512B0.166
TRAF1TNF receptor-associated factor 10.151
ZMYND11zinc finger, MYND-type containing 110.139
COPS2COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)0.137
ZC3H12Azinc finger CCCH-type containing 12A0.096
BBS10Bardet-Biedl syndrome 100.084
TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 10.074
TRAF5TNF receptor-associated factor 50.073
TNIP2TNFAIP3 interacting protein 20.062
C1orf93chromosome 1 open reading frame 930.058
CD14CD14 molecule0.058
CARD11caspase recruitment domain family, member 110.055
IRAK3interleukin-1 receptor-associated kinase 30.040
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.038
TRAF3IP2TRAF3 interacting protein 20.035
TRADDTNFRSF1A-associated via death domain0.029
FASFas (TNF receptor superfamily, member 6)0.028
SMURF1SMAD specific E3 ubiquitin protein ligase 10.027
MAP3K7mitogen-activated protein kinase kinase kinase 70.021
TNFRSF11Atumor necrosis factor receptor superfamily, member 11a, NFKB activator0.020
ING2inhibitor of growth family, member 20.019
GPS1G protein pathway suppressor 10.016
PDPK13-phosphoinositide dependent protein kinase-10.016
ZBTB8Azinc finger and BTB domain containing 8A0.016
FADDFas (TNFRSF6)-associated via death domain0.015
TNFRSF9tumor necrosis factor receptor superfamily, member 90.015
C9orf89chromosome 9 open reading frame 890.015
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.014
KIAA1377KIAA13770.011
PACSIN1protein kinase C and casein kinase substrate in neurons 10.011
LMO4LIM domain only 40.011
PRKCBprotein kinase C, beta0.010
TANKTRAF family member-associated NFKB activator0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism