The network for 'positive regulation of transcription regulatory region dna binding' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of transcription regulatory region dna binding

Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.

NameDescriptionProbabilityFunc Analog Organism
Gata4GATA binding protein 40.993
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.875
Gata6GATA binding protein 60.813
Rxraretinoid X receptor alpha0.599
Isl1ISL1 transcription factor, LIM/homeodomain0.332
Zfpm2zinc finger protein, multitype 20.318
Pitx2paired-like homeodomain transcription factor 20.316
Nos3nitric oxide synthase 3, endothelial cell0.179
Vegfavascular endothelial growth factor A0.177
Jag1jagged 10.169
Trp53transformation related protein 530.153
Shhsonic hedgehog0.136
Hoxa1homeobox A10.119
Fgf8fibroblast growth factor 80.117
Gata5GATA binding protein 50.113
Hand2heart and neural crest derivatives expressed transcript 20.104
Ptpn11protein tyrosine phosphatase, non-receptor type 110.101
Bmp4bone morphogenetic protein 40.087
Mesp1mesoderm posterior 10.085
Tal1T-cell acute lymphocytic leukemia 10.082
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.077
Smad3MAD homolog 3 (Drosophila)0.071
Tbx3T-box 30.069
Prox1prospero-related homeobox 10.066
E2f1E2F transcription factor 10.064
Tgfb2transforming growth factor, beta 20.060
Ntf3neurotrophin 30.060
Hey2hairy/enhancer-of-split related with YRPW motif 20.059
Klf3Kruppel-like factor 3 (basic)0.056
Nf1neurofibromatosis 10.055
Pax3paired box gene 30.049
Vdrvitamin D receptor0.047
Tead3TEA domain family member 30.047
Tgfbr2transforming growth factor, beta receptor II0.047
Snai1snail homolog 1 (Drosophila)0.042
Foxf1aforkhead box F1a0.042
Fgfr2fibroblast growth factor receptor 20.040
Cited2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.040
Csf1colony stimulating factor 1 (macrophage)0.038
Notch1Notch gene homolog 1 (Drosophila)0.034
Hoxb4homeobox B40.034
Acvr1activin A receptor, type 10.034
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.033
Pparaperoxisome proliferator activated receptor alpha0.033
Foxc2forkhead box C20.033
Pax2paired box gene 20.031
Runx1runt related transcription factor 10.030
Map3k7mitogen-activated protein kinase kinase kinase 70.026
Stat3signal transducer and activator of transcription 30.025
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.024
Tbx2T-box 20.024
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.024
Mrps17mitochondrial ribosomal protein S170.024
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.023
Il10interleukin 100.022
Hoxd13homeobox D130.022
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.022
Neurog3neurogenin 30.021
Itga5integrin alpha 5 (fibronectin receptor alpha)0.021
Socs1suppressor of cytokine signaling 10.020
Hic1hypermethylated in cancer 10.020
Zfpm1zinc finger protein, multitype 10.020
Onecut1one cut domain, family member 10.020
Tnfaip3tumor necrosis factor, alpha-induced protein 30.019
Pcsk5proprotein convertase subtilisin/kexin type 50.019
Neurog2neurogenin 20.019
Thrbthyroid hormone receptor beta0.019
Insm1insulinoma-associated 10.019
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.019
Vav2vav 2 oncogene0.019
Ptpn14protein tyrosine phosphatase, non-receptor type 140.019
Tbx20T-box 200.019
Smad6MAD homolog 6 (Drosophila)0.018
Ascl1achaete-scute complex homolog 1 (Drosophila)0.018
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.018
Dll1delta-like 1 (Drosophila)0.017
Cpsf3cleavage and polyadenylation specificity factor 30.017
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.017
Leprleptin receptor0.017
Tbx1T-box 10.017
2810428I15RikRIKEN cDNA 2810428I15 gene0.017
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.017
Bnc1basonuclin 10.017
Ikzf1IKAROS family zinc finger 10.016
Tmem223transmembrane protein 2230.016
Plac1placental specific protein 10.016
Fgf10fibroblast growth factor 100.016
Adam17a disintegrin and metallopeptidase domain 170.016
Chd7chromodomain helicase DNA binding protein 70.016
Six5sine oculis-related homeobox 5 homolog (Drosophila)0.016
Nos2nitric oxide synthase 2, inducible0.016
Ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.016
Psmg1proteasome (prosome, macropain) assembly chaperone 10.015
Npr1natriuretic peptide receptor 10.015
Kitkit oncogene0.015
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.015
Col1a1collagen, type I, alpha 10.015
Desdesmin0.015
Apoa1bpapolipoprotein A-I binding protein0.015
Foxa3forkhead box A30.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TAL1T-cell acute lymphocytic leukemia 10.995
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.804
TRAF3TNF receptor-associated factor 30.656
TRAF2TNF receptor-associated factor 20.595
CD40CD40 molecule, TNF receptor superfamily member 50.499
BIRC3baculoviral IAP repeat containing 30.377
ZNF512Bzinc finger protein 512B0.125
TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)0.119
WRNWerner syndrome, RecQ helicase-like0.096
SETD8SET domain containing (lysine methyltransferase) 80.080
RUNX1runt-related transcription factor 10.080
GATA2GATA binding protein 20.078
ENGendoglin0.060
TRAF6TNF receptor-associated factor 60.058
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.057
SMURF1SMAD specific E3 ubiquitin protein ligase 10.054
GATA1GATA binding protein 1 (globin transcription factor 1)0.050
XRCC1X-ray repair complementing defective repair in Chinese hamster cells 10.044
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.043
IRAK1interleukin-1 receptor-associated kinase 10.038
SOD1superoxide dismutase 1, soluble0.036
TRAF1TNF receptor-associated factor 10.034
SMAD1SMAD family member 10.030
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.030
FSTL1follistatin-like 10.030
TRAF5TNF receptor-associated factor 50.024
TRADDTNFRSF1A-associated via death domain0.024
TBX5T-box 50.023
NUMBLnumb homolog (Drosophila)-like0.022
HTThuntingtin0.020
SMAD3SMAD family member 30.018
SP1Sp1 transcription factor0.016
KLF13Kruppel-like factor 130.014
HAND2heart and neural crest derivatives expressed 20.014
IGF2BP1insulin-like growth factor 2 mRNA binding protein 10.013
RIPK2receptor-interacting serine-threonine kinase 20.013
LMO2LIM domain only 2 (rhombotin-like 1)0.013
HDGFhepatoma-derived growth factor0.013
TNFRSF11Atumor necrosis factor receptor superfamily, member 11a, NFKB activator0.012
CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 30.012
APLFaprataxin and PNKP like factor0.011
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.011
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.010
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.010
GATA4GATA binding protein 40.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism