The network for 'regulation of kidney development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of kidney development

Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.

NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Fgfr2fibroblast growth factor receptor 20.998
Pax2paired box gene 20.996
Bmp4bone morphogenetic protein 40.995
Pax8paired box gene 80.995
Lhx1LIM homeobox protein 10.990
Wt1Wilms tumor 1 homolog0.987
Msx1homeobox, msh-like 10.984
Gli3GLI-Kruppel family member GLI30.983
Fgf8fibroblast growth factor 80.974
Ror2receptor tyrosine kinase-like orphan receptor 20.969
Emx2empty spiracles homolog 2 (Drosophila)0.961
Otx2orthodenticle homolog 2 (Drosophila)0.952
Foxc1forkhead box C10.949
Nr5a1nuclear receptor subfamily 5, group A, member 10.941
Nos3nitric oxide synthase 3, endothelial cell0.935
Gdnfglial cell line derived neurotrophic factor0.924
Hand1heart and neural crest derivatives expressed transcript 10.884
Pax3paired box gene 30.876
Sox9SRY-box containing gene 90.855
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.789
Rarbretinoic acid receptor, beta0.788
Vegfavascular endothelial growth factor A0.771
Ren1renin 1 structural0.768
Hoxd9homeobox D90.745
Pax6paired box gene 60.736
Fgfr1fibroblast growth factor receptor 10.734
Hoxa11homeobox A110.715
Sox7SRY-box containing gene 70.708
Foxc2forkhead box C20.707
Hand2heart and neural crest derivatives expressed transcript 20.702
Hoxa10homeobox A100.689
Hoxb6homeobox B60.683
Hoxd11homeobox D110.682
Wnt4wingless-related MMTV integration site 40.674
Hoxa1homeobox A10.671
Esr1estrogen receptor 1 (alpha)0.653
Pbx1pre B-cell leukemia transcription factor 10.647
Isl1ISL1 transcription factor, LIM/homeodomain0.621
Prrx2paired related homeobox 20.594
Prrx1paired related homeobox 10.594
Hoxb5homeobox B50.593
Eya1eyes absent 1 homolog (Drosophila)0.577
Flt4FMS-like tyrosine kinase 40.577
Nr0b1nuclear receptor subfamily 0, group B, member 10.569
Lhx9LIM homeobox protein 90.545
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.544
Hoxa9homeobox A90.544
Hoxa2homeobox A20.544
Dkk1dickkopf homolog 1 (Xenopus laevis)0.544
Gata6GATA binding protein 60.541
Sox2SRY-box containing gene 20.539
Pitx2paired-like homeodomain transcription factor 20.530
Bdkrb2bradykinin receptor, beta 20.528
Msx2homeobox, msh-like 20.528
Bnc1basonuclin 10.498
C1qacomplement component 1, q subcomponent, alpha polypeptide0.493
Rargretinoic acid receptor, gamma0.486
Tcfap2atranscription factor AP-2, alpha0.483
Tgfb2transforming growth factor, beta 20.472
Bcl2B-cell leukemia/lymphoma 20.463
Hoxd13homeobox D130.452
Hoxc5homeobox C50.451
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.440
Tbx2T-box 20.436
Arandrogen receptor0.426
Tbx3T-box 30.413
Otx1orthodenticle homolog 1 (Drosophila)0.411
Retret proto-oncogene0.411
C1qccomplement component 1, q subcomponent, C chain0.408
Tead3TEA domain family member 30.401
Smad6MAD homolog 6 (Drosophila)0.390
Foxf2forkhead box F20.385
Gbx2gastrulation brain homeobox 20.380
Hoxc8homeobox C80.379
Fshrfollicle stimulating hormone receptor0.379
Hes5hairy and enhancer of split 5 (Drosophila)0.369
Alx4aristaless-like homeobox 40.365
Sall4sal-like 4 (Drosophila)0.362
Kdrkinase insert domain protein receptor0.359
Lhx3LIM homeobox protein 30.348
Foxd2forkhead box D20.339
Hoxb3homeobox B30.339
Zic3zinc finger protein of the cerebellum 30.326
Trp53transformation related protein 530.324
Tbx1T-box 10.319
Ptgs2prostaglandin-endoperoxide synthase 20.310
Foxf1aforkhead box F1a0.306
Hoxd3homeobox D30.306
Phox2bpaired-like homeobox 2b0.304
Zfp503zinc finger protein 5030.304
Hoxa3homeobox A30.301
Adra2badrenergic receptor, alpha 2b0.301
Nos2nitric oxide synthase 2, inducible0.296
C1qbcomplement component 1, q subcomponent, beta polypeptide0.293
Hoxd4homeobox D40.284
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.281
Foxa2forkhead box A20.281
Hoxa5homeobox A50.280
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.979
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.653
VEGFAvascular endothelial growth factor A0.445
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.404
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.400
BMPR1Abone morphogenetic protein receptor, type IA0.323
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.305
NRP1neuropilin 10.299
PJA1praja ring finger 10.108
FSTL1follistatin-like 10.107
BMPR1Bbone morphogenetic protein receptor, type IB0.082
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.057
SKP1S-phase kinase-associated protein 10.056
BMP7bone morphogenetic protein 70.046
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 10.040
COL2A1collagen, type II, alpha 10.039
BTRCbeta-transducin repeat containing0.036
MAGED2melanoma antigen family D, 20.034
TIMP3TIMP metallopeptidase inhibitor 30.032
NKX2-1NK2 homeobox 10.026
SNAI1snail homolog 1 (Drosophila)0.026
GSK3Bglycogen synthase kinase 3 beta0.025
GLIS2GLIS family zinc finger 20.021
AKAP11A kinase (PRKA) anchor protein 110.020
PGFplacental growth factor0.020
PRKAR2Bprotein kinase, cAMP-dependent, regulatory, type II, beta0.020
AMOTL1angiomotin like 10.020
DVL3dishevelled, dsh homolog 3 (Drosophila)0.018
BMP4bone morphogenetic protein 40.016
COL5A1collagen, type V, alpha 10.016
CLDN4claudin 40.015
AKIP1A kinase (PRKA) interacting protein 10.015
PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)0.014
AMOTL2angiomotin like 20.014
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.014
TGFB2transforming growth factor, beta 20.013
EGR3early growth response 30.013
STC1stanniocalcin 10.012
PLCG1phospholipase C, gamma 10.012
RYR2ryanodine receptor 2 (cardiac)0.012
EGR2early growth response 20.011
HOXB5homeobox B50.010
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.010
PAX8paired box 80.010
TP53BP2tumor protein p53 binding protein, 20.010
FBXW11F-box and WD repeat domain containing 110.010
FOXF1forkhead box F10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
FosFBJ osteosarcoma oncogene0.473
Junbjun B proto-oncogene0.409
Egr1early growth response 10.358
Nr4a1nuclear receptor subfamily 4, group A, member 10.152
Egr2early growth response 20.064
Pnliprp2pancreatic lipase-related protein 20.056
Dusp6dual specificity phosphatase 60.053
Dusp1dual specificity phosphatase 10.044
Btg2BTG family, member 20.044
Sp110SP110 nuclear body protein0.043
Ier2immediate early response 20.037
Efnb1ephrin B10.030
Akr1c18aldo-keto reductase family 1, member C180.030
Hoxc4homeo box C40.028
Aqp4aquaporin 40.028
Cmtm2aCKLF-like MARVEL transmembrane domain containing 2A0.026
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.022
Zfp36zinc finger protein 360.021
Fat2FAT tumor suppressor homolog 2 (Drosophila)0.020
Lhx1LIM homeobox 10.020
Klf6Kruppel-like factor 60.019
Cyr61cysteine-rich, angiogenic inducer, 610.019
Flt1FMS-related tyrosine kinase 10.018
Prl3d1Prolactin family 3, subfamily d, member 10.018
Nos3nitric oxide synthase 3, endothelial cell0.018
Krt15keratin 150.018
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.017
Htr2b5-hydroxytryptamine (serotonin) receptor 2B0.016
Krt14keratin 140.016
Stat1signal transducer and activator of transcription 10.016
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.016
Prl8a7prolactin family 8, subfamily a, member 70.015
Prrx1paired related homeobox 10.015
Elk3ELK3, ETS-domain protein0.014
Rararetinoic acid receptor, alpha0.014
Nr4a3nuclear receptor subfamily 4, group A, member 30.014
Cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.014
Gpr20G protein-coupled receptor 200.014
Nek9NIMA (never in mitosis gene a)- related kinase 90.013
Slc14a1solute carrier family 14 (urea transporter), member 10.013
Rab20RAB20, member RAS oncogene family0.013
Igf2insulin-like growth factor 20.013
Fut4fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)0.013
Hoxb8homeo box B80.013
Gja5gap junction protein, alpha 50.012
Clec11aC-type lectin domain family 11, member a0.012
Col8a1collagen, type VIII, alpha 10.012
Trim47tripartite motif-containing 470.012
Cx3cl1chemokine (C-X3-C motif) ligand 10.012
Snai1snail homolog 1 (Drosophila)0.012
Rxraretinoid X receptor alpha0.012
Lgals7lectin, galactoside-binding, soluble, 70.012
Chrm2cholinergic receptor, muscarinic 20.012
Myo1amyosin IA0.012
Hrh1histamine receptor H 10.012
F13a1coagulation factor XIII, A1 polypeptide0.011
Ptger3prostaglandin E receptor 3 (subtype EP3)0.011
Slc15a1solute carrier family 15 (oligopeptide transporter), member 10.011
Ptger4prostaglandin E receptor 4 (subtype EP4)0.011
Fut2fucosyltransferase 2 (secretor status included)0.011
Lim2lens intrinsic membrane protein 20.011
Tspan8tetraspanin 80.011
Ascl1achaete-scute complex homolog 1 (Drosophila)0.011
Has2hyaluronan synthase 20.010
Bmp7bone morphogenetic protein 70.010
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.010
Stx4syntaxin 40.010
Fam70bfamily with sequence similarity 70, member B0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism