The network for 'axoneme assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

axoneme assembly

The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.

NameDescriptionProbabilityFunc Analog Organism
Nr2e1nuclear receptor subfamily 2, group E, member 10.997
Bbs4Bardet-Biedl syndrome 4 (human)0.996
Dclk1doublecortin-like kinase 10.981
Emx1empty spiracles homolog 1 (Drosophila)0.947
Cpeb3cytoplasmic polyadenylation element binding protein 30.921
Hydinhydrocephalus inducing0.766
ND6NADH dehydrogenase subunit 60.758
Ift57intraflagellar transport 57 homolog (Chlamydomonas)0.713
Kif3akinesin family member 3A0.536
Ift74intraflagellar transport 74 homolog (Chlamydomonas)0.516
Bbs9Bardet-Biedl syndrome 9 (human)0.479
Fxr1fragile X mental retardation gene 1, autosomal homolog0.366
Arl6ADP-ribosylation factor-like 60.348
Bbs1Bardet-Biedl syndrome 1 (human)0.335
Ift81intraflagellar transport 81 homolog (Chlamydomonas)0.261
Bbs7Bardet-Biedl syndrome 7 (human)0.191
Crb2crumbs homolog 2 (Drosophila)0.178
Odf2outer dense fiber of sperm tails 20.160
Rcan1regulator of calcineurin 10.149
Ttc8tetratricopeptide repeat domain 80.124
Mks1Meckel syndrome, type 10.115
Ttc21atetratricopeptide repeat domain 21A0.092
Nme5non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)0.088
Cenpc1centromere protein C10.082
Pef1penta-EF hand domain containing 10.074
Armc4armadillo repeat containing 40.071
Dnali1dynein, axonemal, light intermediate polypeptide 10.069
Ulk4unc-51-like kinase 4 (C. elegans)0.061
Dydc2DPY30 domain containing 20.060
Atp6v1dATPase, H+ transporting, lysosomal V1 subunit D0.057
Mecp2methyl CpG binding protein 20.057
Bbs5Bardet-Biedl syndrome 5 (human)0.051
Myef2myelin basic protein expression factor 2, repressor0.050
Abhd8abhydrolase domain containing 80.049
Otx2orthodenticle homolog 2 (Drosophila)0.046
Cfhcomplement component factor h0.045
1700001L19RikRIKEN cDNA 1700001L19 gene0.044
Zscan21zinc finger and SCAN domain containing 210.043
Ift80intraflagellar transport 80 homolog (Chlamydomonas)0.042
B9d1B9 protein domain 10.040
Fmr1fragile X mental retardation syndrome 1 homolog0.040
Fank1fibronectin type 3 and ankyrin repeat domains 10.040
Ak7adenylate kinase 70.039
Pde6dphosphodiesterase 6D, cGMP-specific, rod, delta0.038
Vbp1von Hippel-Lindau binding protein 10.038
Eif4a2eukaryotic translation initiation factor 4A20.037
Sgtasmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha0.037
Efcab7EF-hand calcium binding domain 70.035
Odf3bouter dense fiber of sperm tails 3B0.034
Dync2li1dynein cytoplasmic 2 light intermediate chain 10.032
Aiparyl-hydrocarbon receptor-interacting protein0.032
1110017D15RikRIKEN cDNA 1110017D15 gene0.031
Dyx1c1dyslexia susceptibility 1 candidate 1 homolog (human)0.030
Rab36RAB36, member RAS oncogene family0.030
Cluap1clusterin associated protein 10.029
Tmem231transmembrane protein 2310.029
Ccdc30coiled-coil domain containing 300.029
Dbndd1dysbindin (dystrobrevin binding protein 1) domain containing 10.028
Ubxn6UBX domain protein 60.028
Stk33serine/threonine kinase 330.028
Rad18RAD18 homolog (S. cerevisiae)0.028
1500011H22RikRIKEN cDNA 1500011H22 gene0.027
Rtdr1rhabdoid tumor deletion region gene 10.027
Mdh1bmalate dehydrogenase 1B, NAD (soluble)0.027
Dnm3dynamin 30.027
Dnahc6dynein, axonemal, heavy chain 60.027
6820408C15RikRIKEN cDNA 6820408C15 gene0.026
Adrb2adrenergic receptor, beta 20.026
Ccdc11coiled-coil domain containing 110.025
Criptcysteine-rich PDZ-binding protein0.024
Rsph10b2radial spoke head 10 homolog B (Chlamydomonas)0.024
Camk2bcalcium/calmodulin-dependent protein kinase II, beta0.024
4930579J09RikRIKEN cDNA 4930579J09 gene0.024
Ttll1tubulin tyrosine ligase-like 10.023
Zmynd10zinc finger, MYND domain containing 100.023
Rpgrretinitis pigmentosa GTPase regulator0.023
Dynlrb2dynein light chain roadblock-type 20.023
Cwc27CWC27 spliceosome-associated protein homolog (S. cerevisiae)0.023
Spa17sperm autoantigenic protein 170.022
Dnahc9dynein, axonemal, heavy chain 90.022
IqcaIQ motif containing with AAA domain0.022
Chrna3cholinergic receptor, nicotinic, alpha polypeptide 30.022
Paip2polyadenylate-binding protein-interacting protein 20.022
Ccdc74acoiled-coil domain containing 74A0.022
Ttc18tetratricopeptide repeat domain 180.021
Tekt4tektin 40.021
Ift46intraflagellar transport 46 homolog (Chlamydomonas)0.021
4930455F23RikRIKEN cDNA 4930455F23 gene0.021
Ube2oubiquitin-conjugating enzyme E2O0.021
Fbll1fibrillarin-like 10.021
Fam103a1family with sequence similarity 103, member A10.021
Efcab10EF-hand calcium binding domain 100.021
Kifap3kinesin-associated protein 30.021
1700003M02RikRIKEN cDNA 1700003M02 gene0.020
Zfand6zinc finger, AN1-type domain 60.020
Rabl5RAB, member of RAS oncogene family-like 50.020
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
kif17kinesin family member 170.918
ift88intraflagellar transport 88 homolog0.818
cc2d2acoiled-coil and C2 domain containing 2A0.706
lrrc6leucine rich repeat containing 60.685
ccdc151coiled-coil domain containing 1510.599
ift172intraflagellar transport 1720.479
wdr16WD repeat domain 160.468
ccdc40coiled-coil domain containing 400.436
cluap1clusterin associated protein 10.357
ift57intraflagellar transport protein 570.334
arl13bADP-ribosylation factor-like 13b0.244
cftrcystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)0.241
pkd2polycystic kidney disease 20.212
ift52intraflagellar transport protein 520.202
spsb4asplA/ryanodine receptor domain and SOCS box containing 4a0.121
lrrc50leucine rich repeat containing 500.112
micall2amical-like 2a0.111
rtn4rl2breticulon 4 receptor-like 2b0.095
bbs7Bardet-Biedl syndrome 70.087
ttll6tubulin tyrosine ligase-like family, member 60.085
unc45bunc-45 homolog B (C. elegans)0.072
epb41l5erythrocyte membrane protein band 4.1 like 50.065
mybpc3myosin binding protein C, cardiac0.064
traf3ip1TNF receptor-associated factor 3 interacting protein 10.062
igf1rbinsulin-like growth factor 1b receptor0.061
LOC563527brain-specific angiogenesis inhibitor 1-like0.061
gon4lgon-4-like (C.elegans)0.060
mibmind bomb0.056
axin1axin 10.056
lrrc67leucine rich repeat containing 670.056
ift80intraflagellar transport 80 homolog (Chlamydomonas)0.054
morn3MORN repeat containing 30.053
ift81intraflagellar transport 81 homolog0.050
ttc21btetratricopeptide repeat domain 21B0.050
cdc14aaCDC14 cell division cycle 14 homolog A, a0.039
trh1trh1 protein0.037
kif3bkinesin family member 3B0.029
tmem67transmembrane protein 670.028
ift46intraflagellar transport protein 460.027
pacrgPARK2 co-regulated0.025
tmietransmembrane inner ear0.024
ttll3tubulin tyrosine ligase-like family, member 30.024
agbl5ATP/GTP binding protein-like 50.020
ccdc113coiled-coil domain containing 1130.020
ndr1nodal-related 10.020
ntlano tail a0.020
capslacalcyphosine-like a0.020
ttc26tetratricopeptide repeat domain 260.020
rtf1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.019
myo7aamyosin VIIAa0.019
prdm9PR domain containing 90.018
nexnnexilin (F actin binding protein)0.018
e2f5E2F transcription factor 50.017
zte25zebrafish testis-expressed 250.017
ventventral expressed homeobox0.017
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.016
LOC100535637rho guanine nucleotide exchange factor 12-like0.016
dzip1DAZ interacting protein 10.016
jag2jagged 20.015
mks1meckel syndrome, type 10.015
cep290centrosomal protein 2900.015
tsga14testis specific, 140.014
arl6ADP-ribosylation factor-like 60.013
smyd1bSET and MYND domain containing 1b0.013
tab2TGF-beta activated kinase 1/MAP3K7 binding protein 20.013
tnpo3transportin 30.013
mgc35261lhypothetical protein MGC35261-like (H. sapiens)0.013
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.012
tctex1d2Tctex1 domain containing 20.012
pls1plastin 1 (I isoform)0.012
ahcyl2S-adenosylhomocysteine hydrolase-like 20.012
arhgap11aRho GTPase activating protein 11A0.012
pnp6purine nucleoside phosphorylase 60.012
tex9testis expressed 90.011
csnk1g2acasein kinase 1, gamma 2a0.011
snx27sorting nexin family member 270.011
fhlafour and a half LIM domains a0.011
kifc1kinesin family member C10.011
stk36serine/threonine kinase 36 (fused homolog, Drosophila)0.011
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
tilBtouch insensitive larva B0.989
ana1anastral spindle 10.968
CG3875CG3875 gene product from transcript CG3875-RA0.803
kl-3male fertility factor kl30.593
betaTub85Dbeta-Tubulin at 85D0.329
Cep135CG17081 gene product from transcript CG17081-RB0.268
Cyt-c-dCytochrome c distal0.236
TTLL3BTubulin tyrosine ligase-like 3B0.191
CG1625CG1625 gene product from transcript CG1625-RB0.125
Sas-4CG10061 gene product from transcript CG10061-RA0.121
SAKSak kinase0.082
Prosalpha6TProteasome alpha6T subunit0.067
CG34168CG34168 gene product from transcript CG34168-RA0.065
djdon juan0.055
CG7742CG7742 gene product from transcript CG7742-RA0.052
nimC1nimrod C10.047
Mst87FMale-specific RNA 87F0.044
Mst84DaMale-specific RNA 84Da0.041
HtrA2CG8464 gene product from transcript CG8464-RA0.040
CG14840CG14840 gene product from transcript CG14840-RA0.036
CG4328CG4328 gene product from transcript CG4328-RB0.032
CG31998CG31998 gene product from transcript CG31998-RA0.031
CG4998CG4998 gene product from transcript CG4998-RB0.031
Nup154Nucleoporin 1540.031
CG5440CG5440 gene product from transcript CG5440-RA0.031
CG11043CG11043 gene product from transcript CG11043-RA0.029
CG4329CG4329 gene product from transcript CG4329-RB0.028
lkb1CG9374 gene product from transcript CG9374-RJ0.025
nmdno mitochondrial derivative0.024
CG17666CG17666 gene product from transcript CG17666-RA0.023
CG13891CG13891 gene product from transcript CG13891-RA0.023
CG5674CG5674 gene product from transcript CG5674-RB0.023
CG14921CG14921 gene product from transcript CG14921-RA0.022
OliOlig family0.022
Rpt6RCG2241 gene product from transcript CG2241-RA0.022
nompAno mechanoreceptor potential A0.021
CG13039CG13039 gene product from transcript CG13039-RA0.021
CG17086CG17086 gene product from transcript CG17086-RA0.019
Mst98CaMale-specific RNA 98Ca0.019
KP78bCG17216 gene product from transcript CG17216-RB0.018
CG6971CG6971 gene product from transcript CG6971-RA0.018
CG32236CG32236 gene product from transcript CG32236-RA0.018
CG11635CG11635 gene product from transcript CG11635-RA0.018
Ube3aUbiquitin protein ligase E3A0.018
CG31169CG31169 gene product from transcript CG31169-RB0.017
CG15657CG15657 gene product from transcript CG15657-RA0.017
Cp110CG14617 gene product from transcript CG14617-RB0.017
CG16984CG16984 gene product from transcript CG16984-RA0.016
CG7335CG7335 gene product from transcript CG7335-RA0.016
Mst84DcMale-specific RNA 84Dc0.015
CG4907CG4907 gene product from transcript CG4907-RA0.015
CG16781CG16781 gene product from transcript CG16781-RA0.015
nmdyn-D7CG8362 gene product from transcript CG8362-RA0.015
CG5742CG5742 gene product from transcript CG5742-RA0.014
CG9313CG9313 gene product from transcript CG9313-RA0.014
CG12783CG12783 gene product from transcript CG12783-RA0.014
CG15482CG15482 gene product from transcript CG15482-RA0.014
CG15200CG15200 gene product from transcript CG15200-RA0.014
CG7051CG7051 gene product from transcript CG7051-RA0.014
CG31988CG31988 gene product from transcript CG31988-RA0.014
qkr54Bquaking related 54B0.014
CG42360CG42360 gene product from transcript CG42360-RA0.014
CG32392CG32392 gene product from transcript CG32392-RB0.014
UnrUpstream of N-ras0.013
CG31473CG31473 gene product from transcript CG31473-RA0.013
CG17669CG17669 gene product from transcript CG17669-RA0.013
CG11562CG11562 gene product from transcript CG11562-RA0.013
cp309CG33957 gene product from transcript CG33957-RB0.013
nompBno mechanoreceptor potential B0.013
CG11656CG11656 gene product from transcript CG11656-RA0.013
CAPCG18408 gene product from transcript CG18408-RI0.013
CG12184CG12184 gene product from transcript CG12184-RA0.013
Suv4-20CG13363 gene product from transcript CG13363-RA0.013
CG7295CG7295 gene product from transcript CG7295-RA0.013
CG7024CG7024 gene product from transcript CG7024-RA0.013
CG1979CG1979 gene product from transcript CG1979-RA0.012
CG14537CG14537 gene product from transcript CG14537-RA0.012
CG13526CG13526 gene product from transcript CG13526-RA0.012
CG9975CG9975 gene product from transcript CG9975-RA0.012
CG17375CG17375 gene product from transcript CG17375-RB0.012
CG14932CG14932 gene product from transcript CG14932-RC0.012
Ant2Adenine nucleotide translocase 20.012
RpL10AaRibosomal protein L10Aa0.012
katanin-60katanin 600.012
Gienovel GTPase indispensable for equal segregation of chromosomes0.011
CG13983CG13983 gene product from transcript CG13983-RA0.011
CG13168CG13168 gene product from transcript CG13168-RC0.011
Mst84DbMale-specific RNA 84Db0.011
Upf2CG2253 gene product from transcript CG2253-RA0.011
CG16837CG16837 gene product from transcript CG16837-RA0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CENPJcentromere protein J0.998
SASS6spindle assembly 6 homolog (C. elegans)0.906
STILSCL/TAL1 interrupting locus0.624
CYFIP2cytoplasmic FMR1 interacting protein 20.505
LCMT1leucine carboxyl methyltransferase 10.440
UBR3ubiquitin protein ligase E3 component n-recognin 3 (putative)0.414
UBR1ubiquitin protein ligase E3 component n-recognin 10.200
CYFIP1cytoplasmic FMR1 interacting protein 10.147
LNX1ligand of numb-protein X 10.103
PTBP2polypyrimidine tract binding protein 20.071
KCTD4potassium channel tetramerisation domain containing 40.053
TSC22D4TSC22 domain family, member 40.051
STAG2stromal antigen 20.050
UBE2Aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.048
GKAP1G kinase anchoring protein 10.044
RB1CC1RB1-inducible coiled-coil 10.037
ZBTB8Azinc finger and BTB domain containing 8A0.037
RAD18RAD18 homolog (S. cerevisiae)0.036
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.035
OFD1oral-facial-digital syndrome 10.034
TBK1TANK-binding kinase 10.033
AGTPBP1ATP/GTP binding protein 10.032
MASTLmicrotubule associated serine/threonine kinase-like0.029
TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase0.029
C19orf50chromosome 19 open reading frame 500.029
CALCOCO2calcium binding and coiled-coil domain 20.029
SIAH1seven in absentia homolog 1 (Drosophila)0.028
TDRD3tudor domain containing 30.028
RBM7RNA binding motif protein 70.025
CEP152centrosomal protein 152kDa0.025
NCK2NCK adaptor protein 20.025
TBL1XR1transducin (beta)-like 1 X-linked receptor 10.025
KCNRGpotassium channel regulator0.024
ANKRD32ankyrin repeat domain 320.023
NSFN-ethylmaleimide-sensitive factor0.023
SMC3structural maintenance of chromosomes 30.020
PSMF1proteasome (prosome, macropain) inhibitor subunit 1 (PI31)0.020
TANKTRAF family member-associated NFKB activator0.020
LDOC1leucine zipper, down-regulated in cancer 10.019
CEP135centrosomal protein 135kDa0.019
TBKBP1TBK1 binding protein 10.019
SUZ12suppressor of zeste 12 homolog (Drosophila)0.019
CENPEcentromere protein E, 312kDa0.019
NT5C25'-nucleotidase, cytosolic II0.018
DPPA2developmental pluripotency associated 20.018
SP3Sp3 transcription factor0.017
BMI1BMI1 polycomb ring finger oncogene0.017
DAXXdeath-domain associated protein0.016
NEDD1neural precursor cell expressed, developmentally down-regulated 10.016
PRKAA1protein kinase, AMP-activated, alpha 1 catalytic subunit0.016
KNTC1kinetochore associated 10.015
POLHpolymerase (DNA directed), eta0.015
MIS18BP1MIS18 binding protein 10.014
ZMYND10zinc finger, MYND-type containing 100.014
MATR3matrin 30.014
STAG1stromal antigen 10.014
STAU1staufen, RNA binding protein, homolog 1 (Drosophila)0.014
ZCCHC10zinc finger, CCHC domain containing 100.014
BRIP1BRCA1 interacting protein C-terminal helicase 10.014
FMR1fragile X mental retardation 10.013
KHDRBS2KH domain containing, RNA binding, signal transduction associated 20.013
PLK4polo-like kinase 40.013
CEP57centrosomal protein 57kDa0.013
WDHD1WD repeat and HMG-box DNA binding protein 10.013
CCDC85Bcoiled-coil domain containing 85B0.012
RNF20ring finger protein 200.012
PHIPpleckstrin homology domain interacting protein0.012
UBR2ubiquitin protein ligase E3 component n-recognin 20.012
RAD21RAD21 homolog (S. pombe)0.012
KTN1kinectin 1 (kinesin receptor)0.011
ZNF408zinc finger protein 4080.011
LAMTOR3late endosomal/lysosomal adaptor, MAPK and MTOR activator 30.011
DCUN1D1DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)0.011
KHDRBS3KH domain containing, RNA binding, signal transduction associated 30.011
NUP153nucleoporin 153kDa0.010
HSF2heat shock transcription factor 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism