The network for 'prostaglandin metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

prostaglandin metabolic process

The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.

NameDescriptionProbabilityFunc Analog Organism
Anxa5annexin A50.477
S100a11S100 calcium binding protein A11 (calizzarin)0.115
RT1-DaRT1 class II, locus Da0.107
Gsta3glutathione S-transferase A30.102
Syt4synaptotagmin IV0.068
Il6interleukin 60.037
RT1-BaRT1 class II, locus Ba0.035
Lgals3lectin, galactoside-binding, soluble, 30.033
RT1-BbRT1 class II, locus Bb0.031
RT1-DMbRT1 class II, locus DMb0.031
RT1-Db1RT1 class II, locus Db10.028
B2mbeta-2 microglobulin0.026
Vimvimentin0.024
Anxa2annexin A20.023
Ctdsp1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 10.023
Akr1c18aldo-keto reductase family 1, member C180.022
Ptgs2prostaglandin-endoperoxide synthase 20.016
Anxa1annexin A10.016
Prss1protease, serine, 1 (trypsin 1)0.015
S100a10S100 calcium binding protein A100.015
Slc22a25solute carrier family 22, member 250.015
Prkcdprotein kinase C, delta0.015
Taglntransgelin0.014
Serpinb1aserine (or cysteine) proteinase inhibitor, clade B, member 1a0.013
Cyp1b1cytochrome P450, family 1, subfamily b, polypeptide 10.013
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.012
Prkacbprotein kinase, cAMP dependent, catalytic, beta0.012
Ehd2EH-domain containing 20.012
Krt4keratin 40.011
Serpinb6aserine (or cysteine) peptidase inhibitor, clade B, member 6a0.011
Ifit1interferon-induced protein with tetratricopeptide repeats 10.011
Cnn1calponin 1, basic, smooth muscle0.011
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.011
Rad23bRAD23 homolog B (S. cerevisiae)0.010
Gfapglial fibrillary acidic protein0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.870
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.849
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.556
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.464
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.151
LDHAlactate dehydrogenase A0.146
PPIDpeptidylprolyl isomerase D0.080
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.064
MAP2K4mitogen-activated protein kinase kinase 40.058
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.041
PKM2pyruvate kinase, muscle0.034
KIAA1712KIAA17120.025
IL8interleukin 80.020
CXCR4chemokine (C-X-C motif) receptor 40.018
GPIglucose-6-phosphate isomerase0.017
EP300E1A binding protein p3000.017
KAT2BK(lysine) acetyltransferase 2B0.017
XPO7exportin 70.017
CXCL2chemokine (C-X-C motif) ligand 20.015
CXCL3chemokine (C-X-C motif) ligand 30.015
PDPK13-phosphoinositide dependent protein kinase-10.014
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.014
ALDOAaldolase A, fructose-bisphosphate0.013
MAPK8mitogen-activated protein kinase 80.013
TRMT112tRNA methyltransferase 11-2 homolog (S. cerevisiae)0.013
PLAURplasminogen activator, urokinase receptor0.012
PGK1phosphoglycerate kinase 10.012
TPI1triosephosphate isomerase 10.012
ENO1enolase 1, (alpha)0.012
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.012
AZIN1antizyme inhibitor 10.011
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.011
PRMT2protein arginine methyltransferase 20.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
H2-Aahistocompatibility 2, class II antigen A, alpha0.902
H2-Eb1histocompatibility 2, class II antigen E beta0.639
H2-Ab1histocompatibility 2, class II antigen A, beta 10.261
Gstm1glutathione S-transferase, mu 10.242
H2-DMahistocompatibility 2, class II, locus DMa0.234
Esr1estrogen receptor 1 (alpha)0.193
Apcadenomatosis polyposis coli0.184
Ptgs2prostaglandin-endoperoxide synthase 20.160
Platplasminogen activator, tissue0.143
Il6interleukin 60.136
Cav1caveolin 1, caveolae protein0.127
Arandrogen receptor0.108
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.105
Plauplasminogen activator, urokinase0.095
Clockcircadian locomotor output cycles kaput0.089
Ptgs1prostaglandin-endoperoxide synthase 10.084
Gsta3glutathione S-transferase, alpha 30.067
Arntlaryl hydrocarbon receptor nuclear translocator-like0.065
Slc34a1solute carrier family 34 (sodium phosphate), member 10.061
Gm3776predicted gene 37760.061
Il1r1interleukin 1 receptor, type I0.058
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.054
Kiss1KiSS-1 metastasis-suppressor0.050
Cd14CD14 antigen0.050
Mmp9matrix metallopeptidase 90.049
Ces1dcarboxylesterase 1D0.049
Ch25hcholesterol 25-hydroxylase0.048
Nos2nitric oxide synthase 2, inducible0.046
Ccl2chemokine (C-C motif) ligand 20.046
Hrhairless0.045
Gsta4glutathione S-transferase, alpha 40.042
Alox5aparachidonate 5-lipoxygenase activating protein0.039
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.037
Cyp2j5cytochrome P450, family 2, subfamily j, polypeptide 50.036
Ppargperoxisome proliferator activated receptor gamma0.035
Procrprotein C receptor, endothelial0.034
Thbs1thrombospondin 10.029
Ren1renin 1 structural0.029
SetSET nuclear oncogene0.028
Leprleptin receptor0.028
Nup153nucleoporin 1530.027
Mtmr1myotubularin related protein 10.027
Aldh1a1aldehyde dehydrogenase family 1, subfamily A10.026
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.025
Dhx15DEAH (Asp-Glu-Ala-His) box polypeptide 150.025
Anxa8annexin A80.025
Alox5arachidonate 5-lipoxygenase0.025
Egr1early growth response 10.025
Gstt1glutathione S-transferase, theta 10.023
Cyp2f2cytochrome P450, family 2, subfamily f, polypeptide 20.023
Ahraryl-hydrocarbon receptor0.023
Ednrbendothelin receptor type B0.023
Sphk1sphingosine kinase 10.023
Hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 70.023
Tlr4toll-like receptor 40.022
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.022
Igfbp6insulin-like growth factor binding protein 60.022
C3complement component 30.021
Adh1alcohol dehydrogenase 1 (class I)0.021
Slc12a1solute carrier family 12, member 10.021
Ptger2prostaglandin E receptor 2 (subtype EP2)0.021
Spp1secreted phosphoprotein 10.020
Mapk14mitogen-activated protein kinase 140.019
Aldh1a7aldehyde dehydrogenase family 1, subfamily A70.019
C1qccomplement component 1, q subcomponent, C chain0.019
Defb1defensin beta 10.018
Stra6stimulated by retinoic acid gene 60.018
Ghrgrowth hormone receptor0.017
F13bcoagulation factor XIII, beta subunit0.017
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.017
Trpv4transient receptor potential cation channel, subfamily V, member 40.017
Cdkn1bcyclin-dependent kinase inhibitor 1B0.017
Crbncereblon0.017
Ghgrowth hormone0.017
Ccl17chemokine (C-C motif) ligand 170.016
C1qacomplement component 1, q subcomponent, alpha polypeptide0.016
Sult1d1sulfotransferase family 1D, member 10.016
Cxcl1chemokine (C-X-C motif) ligand 10.016
CebpdCCAAT/enhancer binding protein (C/EBP), delta0.016
Aldh6a1aldehyde dehydrogenase family 6, subfamily A10.016
Lbplipopolysaccharide binding protein0.015
Gja1gap junction protein, alpha 10.015
Rbm15RNA binding motif protein 150.015
Malmyelin and lymphocyte protein, T-cell differentiation protein0.014
Inmtindolethylamine N-methyltransferase0.014
Smad3MAD homolog 3 (Drosophila)0.014
Osmroncostatin M receptor0.014
Cyp3a13cytochrome P450, family 3, subfamily a, polypeptide 130.014
Timp1tissue inhibitor of metalloproteinase 10.014
Hbb-b1hemoglobin, beta adult major chain0.014
Tm4sf1transmembrane 4 superfamily member 10.014
Hsph1heat shock 105kDa/110kDa protein 10.013
Wwtr1WW domain containing transcription regulator 10.013
S100a8S100 calcium binding protein A8 (calgranulin A)0.013
Baatbile acid-Coenzyme A: amino acid N-acyltransferase0.013
Krt32keratin 320.013
Adh7alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide0.013
Mslnmesothelin0.013
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.013
Admadrenomedullin0.012
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism