The network for 'regulation of cellular response to insulin stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cellular response to insulin stimulus

Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus.

NameDescriptionProbabilityFunc Analog Organism
Sirpasignal-regulatory protein alpha0.216
Cfpcomplement factor properdin0.047
Mobkl2aMOB1, Mps One Binder kinase activator-like 2A (yeast)0.037
Cd14CD14 molecule0.036
Cd83CD83 molecule0.031
Rnf10ring finger protein 100.029
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.028
Sema6bsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B0.027
Slc4a2solute carrier family 4 (anion exchanger), member 20.027
Ptpn6protein tyrosine phosphatase, non-receptor type 60.025
Il1binterleukin 1 beta0.024
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.024
Tgfb1transforming growth factor, beta 10.023
Pik3r1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.022
Cugbp2CUG triplet repeat, RNA binding protein 20.022
Hist1h1ahistone cluster 1, H1a0.021
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.020
Bcl3B-cell CLL/lymphoma 30.020
Map3k11mitogen-activated protein kinase kinase kinase 110.020
Eef2eukaryotic translation elongation factor 20.019
Pip4k2aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha0.018
Grb2growth factor receptor bound protein 20.018
Tpt1tumor protein, translationally-controlled 10.018
Sbno2strawberry notch homolog 2 (Drosophila)0.017
Unc5bunc-5 homolog B (C. elegans)0.017
Ralgdsral guanine nucleotide dissociation stimulator0.017
Arhgap4Rho GTPase activating protein 40.017
Lmnalamin A0.016
Stat3signal transducer and activator of transcription 30.016
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.016
Cd37CD37 molecule0.016
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.016
BidBH3 interacting domain death agonist0.016
Ampd1adenosine monophosphate deaminase 1 (isoform M)0.016
Itgb7integrin, beta 70.015
Fth1ferritin, heavy polypeptide 10.015
Stat6signal transducer and activator of transcription 60.015
Jak2Janus kinase 20.015
Arl5cADP-ribosylation factor-like 5C0.015
Metap2methionyl aminopeptidase 20.015
Ptproprotein tyrosine phosphatase, receptor type, O0.015
Pkn2protein kinase N20.014
Map3k8mitogen-activated protein kinase kinase kinase 80.014
Sort1sortilin 10.013
Fmnl1formin-like 10.013
Pou2f2POU class 2 homeobox 20.013
Mpp3membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)0.013
Ppp1r9bprotein phosphatase 1, regulatory subunit 9B0.013
Itgamintegrin, alpha M0.012
Pik3cdphosphoinositide-3-kinase, catalytic, delta polypeptide0.012
Stat5bsignal transducer and activator of transcription 5B0.012
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.012
Prkcbprotein kinase C, beta0.012
Rab1bRAB1B, member RAS oncogene family0.012
CebpeCCAAT/enhancer binding protein (C/EBP), epsilon0.012
Grin2dglutamate receptor, ionotropic, N-methyl D-aspartate 2D0.011
Slasrc-like adaptor0.011
Jak3Janus kinase 30.011
Ptprsprotein tyrosine phosphatase, receptor type, S0.011
Fgafibrinogen alpha chain0.011
Foxp4forkhead box P40.011
Syngr2synaptogyrin 20.011
Il1r2interleukin 1 receptor, type II0.011
Il2rginterleukin 2 receptor, gamma0.011
Socs2suppressor of cytokine signaling 20.011
Sbk1SH3-binding domain kinase 10.011
Ppardperoxisome proliferator-activated receptor delta0.010
Acbd5acyl-Coenzyme A binding domain containing 50.010
Ptger4prostaglandin E receptor 4 (subtype EP4)0.010
Hoxb7homeo box B70.010
Vav1vav 1 guanine nucleotide exchange factor0.010
Egr4early growth response 40.010
Dock8dedicator of cytokinesis 80.010
Phkg1phosphorylase kinase, gamma 10.010
Trib1tribbles homolog 1 (Drosophila)0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
InRInsulin-like receptor0.740
Akt1CG4006 gene product from transcript CG4006-RA0.595
Pi3K92ECG4141 gene product from transcript CG4141-RB0.473
PtenCG5671 gene product from transcript CG5671-RB0.390
IdeInsulin degrading metalloproteinase0.303
Pk61CProtein kinase 61C0.204
chicoCG5686 gene product from transcript CG5686-RB0.187
RanBPMRan-binding protein M0.179
MadMothers against dpp0.147
S6kRPS6-p70-protein kinase0.135
Ilp2Insulin-like peptide 20.113
Lk6CG17342 gene product from transcript CG17342-RA0.107
SmoxSmad on X0.106
CG14815CG14815 gene product from transcript CG14815-RA0.093
CG8443CG8443 gene product from transcript CG8443-RA0.086
p38bCG7393 gene product from transcript CG7393-RA0.075
ThorCG8846 gene product from transcript CG8846-RA0.071
dcodiscs overgrown0.069
picoCG11940 gene product from transcript CG11940-RA0.069
Ilp6Insulin-like peptide 60.065
foxoforkhead box, sub-group O0.058
didumdilute class unconventional myosin0.057
slmbsupernumerary limbs0.057
Sin3ACG8815 gene product from transcript CG8815-RC0.054
MTF-1Metal response element-binding Transcription Factor-10.052
rictorrapamycin-insensitive companion of Tor0.050
Ork1Open rectifier K[+] channel 10.048
CG17273CG17273 gene product from transcript CG17273-RA0.044
LnkCG17367 gene product from transcript CG17367-RC0.043
FatpFatty acid (long chain) transport protein0.042
HLH106Helix loop helix protein 1060.042
ttm50tiny tim 500.032
Kap3Kinesin associated protein 30.029
Atg8aAutophagy-specific gene 8a0.026
TER94CG2331 gene product from transcript CG2331-RA0.026
Su(dx)Suppressor of deltex0.026
Pdp1PAR-domain protein 10.025
sNPFshort neuropeptide F precursor0.025
CycGCyclin G0.023
Pp2B-14DProtein phosphatase 2B at 14D0.023
p53CG33336 gene product from transcript CG33336-RB0.022
Gadd45CG11086 gene product from transcript CG11086-RA0.022
lqfliquid facets0.022
CG14937CG14937 gene product from transcript CG14937-RA0.021
Myo31DFMyosin 31DF0.021
Coq2Coenzyme Q biosynthesis protein 20.021
sNPF-Rshort neuropeptide F receptor0.021
rdgBretinal degeneration B0.021
inaEinactivation no afterpotential E0.020
SpargelCG9809 gene product from transcript CG9809-RB0.019
pashapartner of drosha0.019
Pka-C1cAMP-dependent protein kinase 10.019
maguCG2264 gene product from transcript CG2264-RD0.017
CG8155CG8155 gene product from transcript CG8155-RA0.016
bwabrain washing0.016
B4CG9239 gene product from transcript CG9239-RA0.016
slikSterile20-like kinase0.016
GclcGlutamate-cysteine ligase catalytic subunit0.016
rapretina aberrant in pattern0.015
unc-104CG8566 gene product from transcript CG8566-RB0.015
InvadolysinCG3953 gene product from transcript CG3953-RA0.015
CG8451CG8451 gene product from transcript CG8451-RA0.015
Vap-33-1CG5014 gene product from transcript CG5014-RB0.015
CaMKIICalcium/calmodulin-dependent protein kinase II0.015
Atg1Autophagy-specific gene 10.014
Gef64CGuanine nucleotide exchange factor GEF64C0.014
Nf1Neurofibromin 10.014
CG3308CG3308 gene product from transcript CG3308-RA0.014
Tsp42EfTetraspanin 42Ef0.013
ninaCneither inactivation nor afterpotential C0.013
CG3837CG3837 gene product from transcript CG3837-RA0.013
Tsc1CG6147 gene product from transcript CG6147-RA0.012
MarfMitochondrial assembly regulatory factor0.012
sxcsuper sex combs0.012
CG9007CG9007 gene product from transcript CG9007-RA0.012
CG13890CG13890 gene product from transcript CG13890-RA0.012
Gbeta76CG protein beta-subunit 76C0.012
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PTPN1protein tyrosine phosphatase, non-receptor type 10.994
INSRinsulin receptor0.985
NCOA1nuclear receptor coactivator 10.984
GRB10growth factor receptor-bound protein 100.972
PTPN11protein tyrosine phosphatase, non-receptor type 110.904
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.707
IRS2insulin receptor substrate 20.700
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.615
MAP3K11mitogen-activated protein kinase kinase kinase 110.612
FYNFYN oncogene related to SRC, FGR, YES0.470
CREBBPCREB binding protein0.468
IRS1insulin receptor substrate 10.417
PRKCAprotein kinase C, alpha0.391
RASA1RAS p21 protein activator (GTPase activating protein) 10.380
GRB2growth factor receptor-bound protein 20.301
CUL1cullin 10.272
NCF1neutrophil cytosolic factor 10.270
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.261
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.197
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.190
FBXW11F-box and WD repeat domain containing 110.172
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.151
SH2B1SH2B adaptor protein 10.150
TSC2tuberous sclerosis 20.149
SIRT1sirtuin 10.126
FMR1fragile X mental retardation 10.120
SH3RF1SH3 domain containing ring finger 10.109
BCL3B-cell CLL/lymphoma 30.098
PRKCZprotein kinase C, zeta0.097
PLCG1phospholipase C, gamma 10.096
IGF1Rinsulin-like growth factor 1 receptor0.094
CREB1cAMP responsive element binding protein 10.089
RARAretinoic acid receptor, alpha0.080
NOXA1NADPH oxidase activator 10.079
TSC1tuberous sclerosis 10.074
BTRCbeta-transducin repeat containing0.072
IL1RAPinterleukin 1 receptor accessory protein0.071
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.063
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.062
CAV1caveolin 1, caveolae protein, 22kDa0.056
EEF2Keukaryotic elongation factor-2 kinase0.053
JAK2Janus kinase 20.053
SORBS3sorbin and SH3 domain containing 30.053
MAPTmicrotubule-associated protein tau0.051
SORBS1sorbin and SH3 domain containing 10.051
STAT5Bsignal transducer and activator of transcription 5B0.049
RICTORRPTOR independent companion of MTOR, complex 20.047
MAPK3mitogen-activated protein kinase 30.047
SKP1S-phase kinase-associated protein 10.046
MASP1mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)0.044
CYFIP2cytoplasmic FMR1 interacting protein 20.043
NCK1NCK adaptor protein 10.043
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.043
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.043
PRKCBprotein kinase C, beta0.042
ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 10.040
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.040
YAP1Yes-associated protein 10.039
RHOUras homolog gene family, member U0.039
C17orf28chromosome 17 open reading frame 280.038
SHC1SHC (Src homology 2 domain containing) transforming protein 10.037
IL1R1interleukin 1 receptor, type I0.037
PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.037
LIMS1LIM and senescent cell antigen-like domains 10.036
MAP3K5mitogen-activated protein kinase kinase kinase 50.035
CREBZFCREB/ATF bZIP transcription factor0.035
ITGB1BP3integrin beta 1 binding protein 30.034
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 20.034
YES1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.031
KAT2BK(lysine) acetyltransferase 2B0.030
RAB6ARAB6A, member RAS oncogene family0.029
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.028
TRIM9tripartite motif containing 90.027
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.027
EP300E1A binding protein p3000.026
NCF4neutrophil cytosolic factor 4, 40kDa0.025
COASYCoA synthase0.025
EPORerythropoietin receptor0.024
SOCS3suppressor of cytokine signaling 30.023
MAPK14mitogen-activated protein kinase 140.023
PDPK13-phosphoinositide dependent protein kinase-10.022
CEP250centrosomal protein 250kDa0.022
DDAH2dimethylarginine dimethylaminohydrolase 20.021
COPS2COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)0.021
FOXO3forkhead box O30.021
GSK3Bglycogen synthase kinase 3 beta0.021
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.020
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.020
CAV2caveolin 20.020
TBL1XR1transducin (beta)-like 1 X-linked receptor 10.020
NOP58NOP58 ribonucleoprotein homolog (yeast)0.020
SOS1son of sevenless homolog 1 (Drosophila)0.020
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.019
ACACAacetyl-CoA carboxylase alpha0.019
PTK2BPTK2B protein tyrosine kinase 2 beta0.019
SH2D1ASH2 domain containing 1A0.019
STMN2stathmin-like 20.018
CSNK1G3casein kinase 1, gamma 30.018
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.018
PTENphosphatase and tensin homolog0.018
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Leprleptin receptor1.000
Insrinsulin receptor0.902
Jak2Janus kinase 20.438
Egfrepidermal growth factor receptor0.389
FynFyn proto-oncogene0.388
Clockcircadian locomotor output cycles kaput0.333
Cdkn1bcyclin-dependent kinase inhibitor 1B0.321
Irs2insulin receptor substrate 20.249
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.173
Ldb3LIM domain binding 30.157
Per2period homolog 2 (Drosophila)0.156
Lipelipase, hormone sensitive0.146
Nos1nitric oxide synthase 1, neuronal0.141
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.129
Prkceprotein kinase C, epsilon0.128
Arntlaryl hydrocarbon receptor nuclear translocator-like0.120
Plcg1phospholipase C, gamma 10.118
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.117
Tsc2tuberous sclerosis 20.113
Dok2docking protein 20.099
Dok1docking protein 10.088
Inpp5dinositol polyphosphate-5-phosphatase D0.086
Irs1insulin receptor substrate 10.083
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.081
SrcRous sarcoma oncogene0.079
Nr3c1nuclear receptor subfamily 3, group C, member 10.077
Igf1rinsulin-like growth factor I receptor0.076
CblCasitas B-lineage lymphoma0.072
Nf1neurofibromatosis 10.071
Grb2growth factor receptor bound protein 20.070
Serpina1cserine (or cysteine) peptidase inhibitor, clade A, member 1C0.067
Ghrgrowth hormone receptor0.066
Stat5asignal transducer and activator of transcription 5A0.065
Smad3MAD homolog 3 (Drosophila)0.065
Tsc1tuberous sclerosis 10.064
Esr1estrogen receptor 1 (alpha)0.061
Vav2vav 2 oncogene0.061
Tgfb1transforming growth factor, beta 10.060
Foxo1forkhead box O10.059
Stat5bsignal transducer and activator of transcription 5B0.059
Nck2non-catalytic region of tyrosine kinase adaptor protein 20.058
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.054
Csf1colony stimulating factor 1 (macrophage)0.054
Igf2rinsulin-like growth factor 2 receptor0.052
Ep300E1A binding protein p3000.051
Stat3signal transducer and activator of transcription 30.050
Il1ainterleukin 1 alpha0.049
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.049
Nedd4neural precursor cell expressed, developmentally down-regulated 40.047
Socs1suppressor of cytokine signaling 10.046
Ptk2bPTK2 protein tyrosine kinase 2 beta0.046
Agtr1aangiotensin II receptor, type 1a0.045
Cav1caveolin 1, caveolae protein0.043
Gab2growth factor receptor bound protein 2-associated protein 20.043
NsfN-ethylmaleimide sensitive fusion protein0.042
Nos3nitric oxide synthase 3, endothelial cell0.041
Serping1serine (or cysteine) peptidase inhibitor, clade G, member 10.041
Il1r1interleukin 1 receptor, type I0.041
Pnpla2patatin-like phospholipase domain containing 20.040
Itgb1integrin beta 1 (fibronectin receptor beta)0.040
Cry1cryptochrome 1 (photolyase-like)0.040
Fmr1fragile X mental retardation syndrome 1 homolog0.040
Socs2suppressor of cytokine signaling 20.039
Ppargperoxisome proliferator activated receptor gamma0.038
Nr1h4nuclear receptor subfamily 1, group H, member 40.038
Foxo4forkhead box O40.038
Cishcytokine inducible SH2-containing protein0.036
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.036
Tnfrsf13btumor necrosis factor receptor superfamily, member 13b0.035
Fcgr2bFc receptor, IgG, low affinity IIb0.035
Tbk1TANK-binding kinase 10.034
Plxna1plexin A10.034
Tekendothelial-specific receptor tyrosine kinase0.033
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.033
Apoa1apolipoprotein A-I0.033
BlnkB-cell linker0.032
Il6stinterleukin 6 signal transducer0.032
Jak1Janus kinase 10.031
Vhlvon Hippel-Lindau tumor suppressor0.030
Npc1Niemann Pick type C10.030
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.030
Socs3suppressor of cytokine signaling 30.030
FasFas (TNF receptor superfamily member 6)0.030
Apoc4apolipoprotein C-IV0.030
Ate1arginyltransferase 10.030
Fxr1fragile X mental retardation gene 1, autosomal homolog0.029
Cry2cryptochrome 2 (photolyase-like)0.029
Per1period homolog 1 (Drosophila)0.028
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.028
Nf2neurofibromatosis 20.028
Il1binterleukin 1 beta0.028
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.027
Grb10growth factor receptor bound protein 100.027
Vav3vav 3 oncogene0.027
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.027
Casp4caspase 4, apoptosis-related cysteine peptidase0.027
Asb6ankyrin repeat and SOCS box-containing 60.027
Il6interleukin 60.026
Efnb1ephrin B10.026
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism