The network for 'organ induction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

organ induction

The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ.

NameDescriptionProbabilityFunc Analog Organism
Olfml2bolfactomedin-like 2B0.134
Cxxc4CXXC finger 40.127
Syt9synaptotagmin IX0.100
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.081
Prrx1paired related homeobox 10.077
Tbr1T-box, brain, 10.077
Gtf2a1general transcription factor IIA, 10.075
Glg1golgi apparatus protein 10.060
Kcnh7potassium voltage-gated channel, subfamily H (eag-related), member 70.051
Unc5bunc-5 homolog B (C. elegans)0.047
Synposynaptopodin0.042
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.041
F13a1coagulation factor XIII, A1 polypeptide0.040
Pde3aphosphodiesterase 3A, cGMP inhibited0.038
Slc22a2solute carrier family 22 (organic cation transporter), member 20.038
GperG protein-coupled estrogen receptor 10.037
Vsnl1visinin-like 10.036
Chrna1cholinergic receptor, nicotinic, alpha 1 (muscle)0.036
Fgf5fibroblast growth factor 50.036
Cpxm2carboxypeptidase X (M14 family), member 20.034
Tpc1808tropic 18080.034
Gja3gap junction protein, alpha 30.034
Cdh6cadherin 60.034
Pdcphosducin0.034
Myo1cmyosin IC0.034
Spink3serine peptidase inhibitor, Kazal type 30.033
Tnni1troponin I type 1 (skeletal, slow)0.032
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.032
Paqr8progestin and adipoQ receptor family member VIII0.030
Ednraendothelin receptor type A0.030
Ptger2prostaglandin E receptor 2 (subtype EP2)0.029
Cacng6calcium channel, voltage-dependent, gamma subunit 60.029
Ugt2a1UDP glucuronosyltransferase 2 family, polypeptide A10.029
Cpa3carboxypeptidase A3, mast cell0.029
Csrp3cysteine and glycine-rich protein 30.029
Adamts13ADAM metallopeptidase with thrombospondin type 1 motif, 130.028
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.028
Gabrg3gamma-aminobutyric acid (GABA) A receptor, gamma 30.027
Prap1proline-rich acidic protein 10.027
Pde7bphosphodiesterase 7B0.027
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.027
Mcammelanoma cell adhesion molecule0.027
Bdkrb2bradykinin receptor B20.026
Rcvrnrecoverin0.026
Slc1a2solute carrier family 1 (glial high affinity glutamate transporter), member 20.026
Npr3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)0.026
Dlg2discs, large homolog 2 (Drosophila)0.025
Kcnmb1potassium large conductance calcium-activated channel, subfamily M, beta member 10.025
Fgf8fibroblast growth factor 80.025
Serpinb12serpin peptidase inhibitor, clade B (ovalbumin), member 120.025
Masp1mannan-binding lectin serine peptidase 10.025
Btcbetacellulin0.025
Tex101testis expressed 1010.025
Cst12cystatin 120.025
Itga6integrin, alpha 60.024
Cav3caveolin 30.024
Clcn1chloride channel 10.024
Slc13a1solute carrier family 13 (sodium/sulfate symporters), member 10.024
Foxc2forkhead box C20.024
Ptgfrprostaglandin F receptor0.024
Ubtfupstream binding transcription factor, RNA polymerase I0.024
Mmp23matrix metallopeptidase 230.024
Grm7glutamate receptor, metabotropic 70.024
Scnn1bsodium channel, nonvoltage-gated 1, beta0.024
Ucn2urocortin 20.024
Smad3SMAD family member 30.024
Adrb1adrenergic, beta-1-, receptor0.023
Stk11serine/threonine kinase 110.023
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.023
RGD1309821similar to KIAA1161 protein0.022
Tgfb2transforming growth factor, beta 20.022
Cercamcerebral endothelial cell adhesion molecule0.022
Rab3il1RAB3A interacting protein (rabin3)-like 10.022
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.022
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.022
Sox13SRY (sex determining region Y)-box 130.022
Kcnh5potassium voltage-gated channel, subfamily H (eag-related), member 50.022
Slc10a2solute carrier family 10 (sodium/bile acid cotransporter family), member 20.022
Lcn5lipocalin 50.021
Fgf10fibroblast growth factor 100.021
Cmklr1chemokine-like receptor 10.021
Celcarboxyl ester lipase0.021
LOC246267resection-induced TPI (rs11)0.021
Fcer2Fc fragment of IgE, low affinity II, receptor for (CD23)0.021
Acvr1activin A receptor, type I0.021
MrgprfMAS-related GPR, member F0.021
Snap25synaptosomal-associated protein 250.021
Amhanti-Mullerian hormone0.021
Ng23Ng23 protein0.021
Madcam1mucosal vascular addressin cell adhesion molecule 10.021
Asb9ankyrin repeat and SOCS box-containing 90.021
Lipflipase, gastric0.021
Hpcal4hippocalcin-like 40.021
Il13ra2interleukin 13 receptor, alpha 20.020
Stx2syntaxin 20.020
Irs1insulin receptor substrate 10.020
Scgb1a1secretoglobin, family 1A, member 1 (uteroglobin)0.020
Dact3dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)0.020
Stmn4stathmin-like 40.020
Wisp2WNT1 inducible signaling pathway protein 20.020
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
hhhedgehog1.000
wgwingless0.994
EgfrEpidermal growth factor receptor0.965
eyaeyes absent0.935
dppdecapentaplegic0.779
NNotch0.656
enengrailed0.607
armarmadillo0.541
tkvthickveins0.516
argosCG4531 gene product from transcript CG4531-RA0.507
stumpsCG31317 gene product from transcript CG31317-RC0.414
cicubitus interruptus0.373
HHairless0.275
panpangolin0.264
SerSerrate0.262
ptcpatched0.241
sogshort gastrulation0.236
bnlbranchless0.203
rhorhomboid0.194
sdscalloped0.180
pntpointed0.171
par-1CG8201 gene product from transcript CG8201-RA0.148
btlbreathless0.128
Wnt2Wnt oncogene analog 20.117
DlDelta0.116
tshteashirt0.112
hthhomothorax0.099
Ras85DRas oncogene at 85D0.086
spispitz0.086
sqhspaghetti squash0.081
shgshotgun0.076
twitwist0.067
dallydivision abnormally delayed0.061
fz2frizzled 20.056
aopanterior open0.052
fngfringe0.048
gsbgooseberry0.044
wbwing blister0.043
dacdachshund0.042
ribribbon0.042
fzfrizzled0.039
araaraucan0.039
crbcrumbs0.035
kek1kekkon-10.035
kniknirps0.035
UbxUltrabithorax0.034
rtvretroactive0.032
Cdc42CG12530 gene product from transcript CG12530-RA0.030
Wnt4Wnt oncogene analog 40.029
mxcmulti sex combs0.027
varivaricose0.027
DadDaughters against dpp0.026
pbproboscipedia0.025
slislit0.025
gbbglass bottom boat0.025
eyeyeless0.025
hpohippo0.025
coracoracle0.025
hbshibris0.025
sevsevenless0.023
convconvoluted0.022
nkdnaked cuticle0.022
caupcaupolican0.022
abd-Aabdominal A0.021
elBelbow B0.021
dydusky0.020
blowblown fuse0.020
grhgrainy head0.020
gcmglial cells missing0.020
tldtolloid0.019
Mlp84BMuscle LIM protein at 84B0.019
srstripe0.019
effeffete0.019
bibifid0.019
GckIIIGerminal centre kinase III0.019
esgescargot0.019
nrv2nervana 20.018
NotumCG13076 gene product from transcript CG13076-RB0.016
exexpanded0.015
lzlozenge0.015
rprreaper0.015
salmspalt major0.014
stysprouty0.014
NetBNetrin-B0.014
bdgbedraggled0.013
brkbrinker0.013
nimC3nimrod C30.013
bynbrachyenteron0.013
rstroughest0.012
loqsloquacious0.012
trxtrithorax0.012
ftfat0.012
CG8965CG8965 gene product from transcript CG8965-RA0.012
runrunt0.012
porporcupine0.012
HmgcrHMG Coenzyme A reductase0.012
DDichaete0.011
vvlventral veins lacking0.011
Traf4TNF-receptor-associated factor 40.011
ttktramtrack0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FGFR2fibroblast growth factor receptor 20.997
CREBBPCREB binding protein0.995
FGF1fibroblast growth factor 1 (acidic)0.993
FGFR1fibroblast growth factor receptor 10.980
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.963
DVL3dishevelled, dsh homolog 3 (Drosophila)0.959
FOXD3forkhead box D30.947
BMPR1Abone morphogenetic protein receptor, type IA0.942
SP1Sp1 transcription factor0.910
NCOA2nuclear receptor coactivator 20.870
DVL1dishevelled, dsh homolog 1 (Drosophila)0.851
FGF2fibroblast growth factor 2 (basic)0.844
CSNK1Ecasein kinase 1, epsilon0.831
NEDD4neural precursor cell expressed, developmentally down-regulated 40.732
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.717
MYST2MYST histone acetyltransferase 20.672
APCadenomatous polyposis coli0.622
LRP6low density lipoprotein receptor-related protein 60.532
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.467
PLCG1phospholipase C, gamma 10.452
FOXO1forkhead box O10.379
AXIN1axin 10.329
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.320
CTNNBIP1catenin, beta interacting protein 10.265
WWP2WW domain containing E3 ubiquitin protein ligase 20.265
WT1Wilms tumor 10.235
ZNF512Bzinc finger protein 512B0.232
FSTL1follistatin-like 10.208
FZD1frizzled homolog 1 (Drosophila)0.206
SOX2SRY (sex determining region Y)-box 20.205
CEP164centrosomal protein 164kDa0.194
SMAD1SMAD family member 10.183
NCOA1nuclear receptor coactivator 10.165
CTNND1catenin (cadherin-associated protein), delta 10.141
NOSTRINnitric oxide synthase trafficker0.138
ERGv-ets erythroblastosis virus E26 oncogene homolog (avian)0.127
LRRK2leucine-rich repeat kinase 20.119
PRPF3PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)0.115
SMAD7SMAD family member 70.111
MDFIMyoD family inhibitor0.099
HTThuntingtin0.095
CTDSP2CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 20.094
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.093
FOXA1forkhead box A10.092
ZFYVE9zinc finger, FYVE domain containing 90.090
JUPjunction plakoglobin0.090
NCOA6nuclear receptor coactivator 60.071
FHL2four and a half LIM domains 20.068
ARandrogen receptor0.061
HCFC1host cell factor C1 (VP16-accessory protein)0.059
GLIS2GLIS family zinc finger 20.056
PSEN1presenilin 10.054
PIK3CBphosphoinositide-3-kinase, catalytic, beta polypeptide0.053
FBXW11F-box and WD repeat domain containing 110.052
ESR1estrogen receptor 10.050
FGF7fibroblast growth factor 70.049
PTPN11protein tyrosine phosphatase, non-receptor type 110.049
TCF4transcription factor 40.047
FAM110Cfamily with sequence similarity 110, member C0.047
DSPdesmoplakin0.046
ETS2v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)0.046
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.045
PITX1paired-like homeodomain 10.044
SOX10SRY (sex determining region Y)-box 100.043
NOGnoggin0.042
SPRY2sprouty homolog 2 (Drosophila)0.041
FERMT2fermitin family member 20.040
BAHD1bromo adjacent homology domain containing 10.039
HOXB9homeobox B90.038
SHBSrc homology 2 domain containing adaptor protein B0.037
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.036
FZD8frizzled homolog 8 (Drosophila)0.035
EYA1eyes absent homolog 1 (Drosophila)0.035
YAP1Yes-associated protein 10.035
EYA2eyes absent homolog 2 (Drosophila)0.035
FRS2fibroblast growth factor receptor substrate 20.034
WDYHV1WDYHV motif containing 10.034
LBX1ladybird homeobox 10.034
FGF8fibroblast growth factor 8 (androgen-induced)0.033
HOXB5homeobox B50.033
GAB1GRB2-associated binding protein 10.033
BTRCbeta-transducin repeat containing0.031
HOXD10homeobox D100.031
FOXO3forkhead box O30.031
DIDO1death inducer-obliterator 10.030
BMP4bone morphogenetic protein 40.030
ARHGEF1Rho guanine nucleotide exchange factor (GEF) 10.030
SOX11SRY (sex determining region Y)-box 110.030
CDH2cadherin 2, type 1, N-cadherin (neuronal)0.030
HOXC8homeobox C80.030
MCCmutated in colorectal cancers0.030
C16orf48chromosome 16 open reading frame 480.030
CDH3cadherin 3, type 1, P-cadherin (placental)0.030
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.029
POU4F1POU class 4 homeobox 10.028
FGF4fibroblast growth factor 40.028
OTPorthopedia homeobox0.028
NKX2-1NK2 homeobox 10.027
SIX2SIX homeobox 20.027
HOXD13homeobox D130.027
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Pax2paired box gene 20.999
Hoxd11homeobox D110.998
Fgf8fibroblast growth factor 80.998
Gli3GLI-Kruppel family member GLI30.997
Foxc1forkhead box C10.983
Lhx1LIM homeobox protein 10.975
Fgf10fibroblast growth factor 100.959
Vangl2vang-like 2 (van gogh, Drosophila)0.955
Rargretinoic acid receptor, gamma0.954
Fgfr2fibroblast growth factor receptor 20.931
Alx4aristaless-like homeobox 40.926
Dok1docking protein 10.911
Pax8paired box gene 80.902
Pitx2paired-like homeodomain transcription factor 20.893
Retret proto-oncogene0.882
Nodalnodal0.879
Fgfr3fibroblast growth factor receptor 30.872
Hoxd13homeobox D130.845
Gli2GLI-Kruppel family member GLI20.829
Gdnfglial cell line derived neurotrophic factor0.829
Tbx15T-box 150.828
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.818
Nognoggin0.811
Pax3paired box gene 30.788
Prrx1paired related homeobox 10.767
Hoxa13homeobox A130.750
Dkk1dickkopf homolog 1 (Xenopus laevis)0.742
Fgfr1fibroblast growth factor receptor 10.740
Hoxa2homeobox A20.740
Tbx3T-box 30.731
Wnt3awingless-related MMTV integration site 3A0.726
Sall4sal-like 4 (Drosophila)0.718
Twist2twist homolog 2 (Drosophila)0.690
Spry4sprouty homolog 4 (Drosophila)0.674
Chrdchordin0.643
Ptk7PTK7 protein tyrosine kinase 70.642
Msx1homeobox, msh-like 10.618
Foxh1forkhead box H10.608
Hoxa11homeobox A110.606
Ror2receptor tyrosine kinase-like orphan receptor 20.605
Sox9SRY-box containing gene 90.600
Otx2orthodenticle homolog 2 (Drosophila)0.574
Hand1heart and neural crest derivatives expressed transcript 10.560
Rararetinoic acid receptor, alpha0.551
Rarbretinoic acid receptor, beta0.524
Tbx1T-box 10.516
Msx2homeobox, msh-like 20.516
Ror1receptor tyrosine kinase-like orphan receptor 10.502
Eya1eyes absent 1 homolog (Drosophila)0.501
Tcf21transcription factor 210.484
Gli1GLI-Kruppel family member GLI10.477
Prrx2paired related homeobox 20.468
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.462
Hand2heart and neural crest derivatives expressed transcript 20.435
Tcfap2atranscription factor AP-2, alpha0.426
Emx2empty spiracles homolog 2 (Drosophila)0.422
Hoxa1homeobox A10.411
Tbx2T-box 20.403
Foxc2forkhead box C20.376
Pou3f3POU domain, class 3, transcription factor 30.357
Ctnnb1catenin (cadherin associated protein), beta 10.344
Fzd8frizzled homolog 8 (Drosophila)0.341
Smad6MAD homolog 6 (Drosophila)0.337
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.337
Gata6GATA binding protein 60.314
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.313
Btbd17BTB (POZ) domain containing 170.300
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.295
Pitx1paired-like homeodomain transcription factor 10.290
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.289
Acvr1activin A receptor, type 10.286
Vangl1vang-like 1 (van gogh, Drosophila)0.284
Wnt2bwingless related MMTV integration site 2b0.276
Tcfap2ctranscription factor AP-2, gamma0.268
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.255
Bmp7bone morphogenetic protein 70.248
Wnt4wingless-related MMTV integration site 40.247
Wnt6wingless-related MMTV integration site 60.246
Hoxa3homeobox A30.244
Dok2docking protein 20.239
Phox2apaired-like homeobox 2a0.239
Foxf1aforkhead box F1a0.238
Bmp4bone morphogenetic protein 40.235
Fgf18fibroblast growth factor 180.234
Nkx2-1NK2 homeobox 10.231
Dhhdesert hedgehog0.224
Col2a1collagen, type II, alpha 10.222
Ntf3neurotrophin 30.221
Ascl1achaete-scute complex homolog 1 (Drosophila)0.218
Dvl1dishevelled, dsh homolog 1 (Drosophila)0.211
Meox2mesenchyme homeobox 20.211
Fgf9fibroblast growth factor 90.207
Alx3aristaless-like homeobox 30.203
Wt1Wilms tumor 1 homolog0.193
Hoxd9homeobox D90.192
Hoxb6homeobox B60.191
Dlx5distal-less homeobox 50.190
Rxraretinoid X receptor alpha0.180
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.177
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism