The network for 'palate development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

palate development

The biological process whose specific outcome is the progression of the palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The palate is the partition that separates the nasal and oral cavities.

NameDescriptionProbabilityFunc Analog Organism
Tcfe2atranscription factor E2a0.048
Dll3delta-like 3 (Drosophila)0.041
Igfbp5insulin-like growth factor binding protein 50.039
Tgfbr2transforming growth factor, beta receptor II0.035
Shox2short stature homeobox 20.033
Otx1orthodenticle homeobox 10.032
Fgf22fibroblast growth factor 220.031
Cercamcerebral endothelial cell adhesion molecule0.031
Ntf4neurotrophin 40.029
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.027
Ddr2discoidin domain receptor tyrosine kinase 20.026
Col8a1collagen, type VIII, alpha 10.025
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.025
Ucn2urocortin 20.025
Shc2SHC (Src homology 2 domain containing) transforming protein 20.025
Asz1ankyrin repeat, SAM and basic leucine zipper domain containing 10.024
Lsm14aLSM14A, SCD6 homolog A (S. cerevisiae)0.024
Cdh23cadherin 23 (otocadherin)0.024
Crhr2corticotropin releasing hormone receptor 20.023
Ageradvanced glycosylation end product-specific receptor0.023
Ascl1achaete-scute complex homolog 1 (Drosophila)0.023
Spt1salivary protein 10.022
Hdac1lhistone deacetylase 1-like0.021
Plagl1pleiomorphic adenoma gene-like 10.021
Chrna9cholinergic receptor, nicotinic, alpha 90.021
Grm8glutamate receptor, metabotropic 80.021
Svs1seminal vesicle secretory protein 10.021
Sox4SRY (sex determining region Y)-box 40.021
Vax1ventral anterior homeobox 10.021
Olr1271olfactory receptor 12710.020
RGD1564327similar to integrin alpha 80.019
Foxd3forkhead box D30.019
Marcksmyristoylated alanine rich protein kinase C substrate0.019
Cdk5r2cyclin-dependent kinase 5, regulatory subunit 2 (p39)0.019
Smurf2SMAD specific E3 ubiquitin protein ligase 20.019
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.019
Lrrc17leucine rich repeat containing 170.019
Six1SIX homeobox 10.018
Add3adducin 3 (gamma)0.018
Nr5a1nuclear receptor subfamily 5, group A, member 10.018
Tcf12transcription factor 120.018
Fgfr2fibroblast growth factor receptor 20.018
Lnpepleucyl/cystinyl aminopeptidase0.018
Bcl2B-cell CLL/lymphoma 20.018
Ng23Ng23 protein0.018
Odf1outer dense fiber of sperm tails 10.018
LOC681924hypothetical protein LOC6819240.018
Irx4iroquois homeobox 40.018
Col9a1collagen, type IX, alpha 10.018
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.017
Ptpn14protein tyrosine phosphatase, non-receptor type 140.017
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.017
Ednraendothelin receptor type A0.017
Trps1trichorhinophalangeal syndrome I homolog (human)0.017
Kif1bkinesin family member 1B0.017
Fam38bfamily with sequence similarity 38, member B0.017
Agtr2angiotensin II receptor, type 20.017
Slc8a1solute carrier family 8 (sodium/calcium exchanger), member 10.017
Scgb1a1secretoglobin, family 1A, member 1 (uteroglobin)0.017
Rbbp7retinoblastoma binding protein 70.017
Tbx19T-box 190.017
Slc12a3solute carrier family 12 (sodium/chloride transporters), member 30.017
Psmd10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.017
Nlgn2neuroligin 20.017
Gpsm3G-protein signaling modulator 3 (AGS3-like, C. elegans)0.016
Aspgasparaginase homolog (S. cerevisiae)0.016
Itgamintegrin, alpha M0.016
Olr1493olfactory receptor gene Olr14930.016
Clns1achloride channel, nucleotide-sensitive, 1A0.016
Egr4early growth response 40.016
Lims1LIM and senescent cell antigen-like domains 10.016
Gja5gap junction protein, alpha 50.016
Col12a1collagen, type XII, alpha 10.016
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.016
Sulf1sulfatase 10.016
Mdga1MAM domain containing glycosylphosphatidylinositol anchor 10.016
Chrm1cholinergic receptor, muscarinic 10.016
Plod2procollagen lysine, 2-oxoglutarate 5-dioxygenase 20.016
Foxc2forkhead box C20.015
Tspy1testis specific protein, Y-linked 10.015
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.015
Scarf2scavenger receptor class F, member 20.015
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.015
Hsd17b1hydroxysteroid (17-beta) dehydrogenase 10.015
Capn6calpain 60.015
Ptger4prostaglandin E receptor 4 (subtype EP4)0.015
Osbp2oxysterol binding protein 20.015
Bmp4bone morphogenetic protein 40.015
Ltbp1latent transforming growth factor beta binding protein 10.015
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.015
Sema3asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A0.015
Galr2galanin receptor 20.015
Fibcd1fibrinogen C domain containing 10.015
Lrrc36leucine rich repeat containing 360.015
Caskcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.015
Vom1r102vomeronasal 1 receptor 1020.015
Ccdc8coiled-coil domain containing 80.015
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
rargaretinoic acid receptor gamma a0.587
osr1odd-skipped related 1 (Drosophila)0.446
sox9aSRY-box containing gene 9a0.343
bmp4bone morphogenetic protein 40.342
lmo4aLIM domain only 4a0.253
hand2heart and neural crest derivatives expressed transcript 20.211
dlx5adistal-less homeobox gene 5a0.134
vcanaversican a0.133
fras1Fraser syndrome 10.129
nadl1.1neural adhesion molecule L1.10.126
zic1zic family member 1 (odd-paired homolog, Drosophila)0.121
tcf12transcription factor 120.107
tbx1T-box 10.105
tgfb2transforming growth factor, beta 20.096
sox3SRY-box containing gene 30.090
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.088
sall1asal-like 1a (Drosophila)0.086
jag2jagged 20.083
runx2brunt-related transcription factor 2b0.076
s1pr2sphingosine-1-phosphate receptor 20.076
smad7MAD, mothers against decapentaplegic homolog 7 (Drosophila)0.075
neo1neogenin 10.060
fgfrl1bfibroblast growth factor receptor-like 1b0.057
nkx3.2NK3 homeobox 20.054
egr1early growth response 10.051
wnt9awingless-type MMTV integration site family, member 9A0.048
fgf3fibroblast growth factor 30.048
sall4sal-like 4 (Drosophila)0.047
eya1eyes absent homolog 10.047
pax9paired box gene 90.045
gbx2gastrulation brain homeo box 20.043
acvr1bactivin A receptor, type IB0.042
bmp3bone morphogenetic protein 30.042
ndr2nodal-related 20.040
prrx1apaired related homeobox 1a0.039
spry4sprouty (Drosophila) homolog 40.037
cdx4caudal type homeo box transcription factor 40.037
rargbretinoic acid receptor, gamma b0.035
fgf20afibroblast growth factor 20a0.035
cdoncell adhesion molecule-related/down-regulated by oncogenes0.032
dlx6adistal-less homeobox gene 6a0.031
nova2neuro-oncological ventral antigen 20.029
tpm4tropomyosin 40.028
msxemuscle segment homeobox E0.027
mecomMDS1 and EVI1 complex locus0.027
otx1aorthodenticle homolog 1a0.025
pcdh18aprotocadherin 18a0.025
flhfloating head0.025
lhx6LIM homeobox 60.024
fgfr1bfibroblast growth factor receptor 1b0.024
tbx5bT-box 5b0.023
pitx2paired-like homeodomain transcription factor 20.023
smosmoothened homolog (Drosophila)0.023
tmem88atransmembrane protein 88 a0.023
inhbaainhibin, beta Aa0.023
brd4bromodomain containing 40.022
gata6GATA-binding protein 60.022
btbd6aBTB (POZ) domain containing 6a0.022
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.022
nipblbnovel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)0.022
rarabretinoic acid receptor, alpha b0.021
sox11aSRY-box containing gene 11a0.021
otx1borthodenticle homolog 1b0.021
satb2SATB homeobox 20.020
tcf21transcription factor 210.020
bocbrother of CDO0.020
bmp7bbone morphogenetic protein 7b0.019
tbx2bT-box 2b0.019
efna5aephrin A5a0.018
kitbkit receptor b0.018
dlx2adistal-less homeobox gene 2a0.018
gata3GATA-binding protein 30.018
barx1BarH-like homeobox 10.018
bmp2bbone morphogenetic protein 2b0.017
sp8asp8 transcription factor a0.017
fstafollistatin a0.017
dlx4bdistal-less homeobox gene 4b0.017
tcf7transcription factor 7 (T-cell specific, HMG-box)0.017
efnb1ephrin B10.017
vdravitamin D receptor a0.017
tnfsf10l2tumor necrosis factor (ligand) superfamily, member 10 like 20.017
tgfb3transforming growth factor, beta 30.016
loxl3blysyl oxidase-like 3b0.016
sox1aSRY-box containing gene 1a0.016
fgf24fibroblast growth factor 240.016
foxi1forkhead box I10.016
dlx3bdistal-less homeobox gene 3b0.016
bmp2abone morphogenetic protein 2a0.015
pcdh8protocadherin 80.015
jam3bjunctional adhesion molecule 3b0.015
edn1endothelin 10.015
ift88intraflagellar transport 88 homolog0.015
kitakit receptor a0.015
dlx4adistal-less homeobox gene 4a0.015
axin2axin 2 (conductin, axil)0.014
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SMAD3SMAD family member 30.744
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.718
BMP2bone morphogenetic protein 20.689
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.625
COL1A1collagen, type I, alpha 10.563
TGFB1transforming growth factor, beta 10.551
PAX3paired box 30.508
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.424
SMAD2SMAD family member 20.373
COL1A2collagen, type I, alpha 20.355
COL3A1collagen, type III, alpha 10.190
COL6A1collagen, type VI, alpha 10.187
TGFB3transforming growth factor, beta 30.186
POU5F1POU class 5 homeobox 10.156
WNT3Awingless-type MMTV integration site family, member 3A0.154
PPARAperoxisome proliferator-activated receptor alpha0.154
DDR2discoidin domain receptor tyrosine kinase 20.131
SMAD4SMAD family member 40.111
MPDZmultiple PDZ domain protein0.107
CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.100
FOXF2forkhead box F20.097
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.096
COL4A1collagen, type IV, alpha 10.094
SETD8SET domain containing (lysine methyltransferase) 80.086
ADAM17ADAM metallopeptidase domain 170.082
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.078
COL5A2collagen, type V, alpha 20.076
NRP1neuropilin 10.068
SPARCsecreted protein, acidic, cysteine-rich (osteonectin)0.067
NF2neurofibromin 2 (merlin)0.066
FZD1frizzled homolog 1 (Drosophila)0.064
PRRX2paired related homeobox 20.059
THBS1thrombospondin 10.057
BCL9B-cell CLL/lymphoma 90.057
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.056
SH3BP4SH3-domain binding protein 40.052
COL2A1collagen, type II, alpha 10.051
KDM2Blysine (K)-specific demethylase 2B0.049
BMP4bone morphogenetic protein 40.048
SMAD1SMAD family member 10.045
FGF18fibroblast growth factor 180.043
FOXF1forkhead box F10.043
PDGFAplatelet-derived growth factor alpha polypeptide0.042
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.035
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.032
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.032
TBX2T-box 20.032
FZD10frizzled homolog 10 (Drosophila)0.031
TGFBR1transforming growth factor, beta receptor 10.031
WNT5Awingless-type MMTV integration site family, member 5A0.031
WDR5WD repeat domain 50.031
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.030
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.030
WISP1WNT1 inducible signaling pathway protein 10.028
FZD8frizzled homolog 8 (Drosophila)0.027
WNT1wingless-type MMTV integration site family, member 10.026
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.024
TCF4transcription factor 40.024
AQP5aquaporin 50.024
POSTNperiostin, osteoblast specific factor0.023
EGR1early growth response 10.023
MSX1msh homeobox 10.023
SMAD6SMAD family member 60.023
HOXD13homeobox D130.022
DKK1dickkopf homolog 1 (Xenopus laevis)0.021
SOX10SRY (sex determining region Y)-box 100.021
NFIXnuclear factor I/X (CCAAT-binding transcription factor)0.021
PCGF1polycomb group ring finger 10.021
COL13A1collagen, type XIII, alpha 10.021
COL11A1collagen, type XI, alpha 10.020
DLX4distal-less homeobox 40.020
TWIST2twist homolog 2 (Drosophila)0.020
BBS10Bardet-Biedl syndrome 100.019
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.019
PAX2paired box 20.019
JUBjub, ajuba homolog (Xenopus laevis)0.018
FSTL1follistatin-like 10.018
ARandrogen receptor0.018
ADAMTS2ADAM metallopeptidase with thrombospondin type 1 motif, 20.018
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.018
GATA4GATA binding protein 40.018
LRP6low density lipoprotein receptor-related protein 60.018
ZADH2zinc binding alcohol dehydrogenase domain containing 20.017
TWIST1twist homolog 1 (Drosophila)0.017
PAX1paired box 10.017
SIN3ASIN3 homolog A, transcription regulator (yeast)0.017
SUMO2SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)0.017
PLXDC1plexin domain containing 10.017
FGF8fibroblast growth factor 8 (androgen-induced)0.016
SHC1SHC (Src homology 2 domain containing) transforming protein 10.016
SQLEsqualene epoxidase0.016
COL5A1collagen, type V, alpha 10.016
LOXlysyl oxidase0.015
COL18A1collagen, type XVIII, alpha 10.015
SC4MOLsterol-C4-methyl oxidase-like0.015
TP63tumor protein p630.015
LAMA5laminin, alpha 50.015
FOXC1forkhead box C10.015
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gli3GLI-Kruppel family member GLI30.998
Fgfr2fibroblast growth factor receptor 20.998
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.996
Prrx1paired related homeobox 10.993
Tbx3T-box 30.981
Pitx1paired-like homeodomain transcription factor 10.967
Zeb1zinc finger E-box binding homeobox 10.952
Lef1lymphoid enhancer binding factor 10.950
Col1a1collagen, type I, alpha 10.949
Msx1homeobox, msh-like 10.946
Hand1heart and neural crest derivatives expressed transcript 10.928
Nkx2-1NK2 homeobox 10.924
Prrx2paired related homeobox 20.922
Sox9SRY-box containing gene 90.894
Twist2twist homolog 2 (Drosophila)0.892
Runx2runt related transcription factor 20.884
Ascl1achaete-scute complex homolog 1 (Drosophila)0.871
Hoxd11homeobox D110.868
Nr5a1nuclear receptor subfamily 5, group A, member 10.855
Ror2receptor tyrosine kinase-like orphan receptor 20.843
Shhsonic hedgehog0.836
Neurod1neurogenic differentiation 10.834
Bmp7bone morphogenetic protein 70.830
Alx4aristaless-like homeobox 40.820
Pax6paired box gene 60.815
Fgfr1fibroblast growth factor receptor 10.811
Sox2SRY-box containing gene 20.803
Dlx2distal-less homeobox 20.799
Dlx5distal-less homeobox 50.798
Smad4MAD homolog 4 (Drosophila)0.793
Efnb2ephrin B20.790
Gli2GLI-Kruppel family member GLI20.789
Fgf10fibroblast growth factor 100.776
Pax3paired box gene 30.751
Bmpr1abone morphogenetic protein receptor, type 1A0.747
Tgfbr2transforming growth factor, beta receptor II0.740
Msx2homeobox, msh-like 20.736
Pax2paired box gene 20.732
Col2a1collagen, type II, alpha 10.730
Smad6MAD homolog 6 (Drosophila)0.722
Smad3MAD homolog 3 (Drosophila)0.694
Trp63transformation related protein 630.687
Hoxa1homeobox A10.657
Retret proto-oncogene0.656
TiparpTCDD-inducible poly(ADP-ribose) polymerase0.643
Lhx9LIM homeobox protein 90.640
Acvr1activin A receptor, type 10.640
Wnt5awingless-related MMTV integration site 5A0.636
Foxg1forkhead box G10.636
Tgfb2transforming growth factor, beta 20.608
Neurog2neurogenin 20.602
Otx2orthodenticle homolog 2 (Drosophila)0.601
Fzd2frizzled homolog 2 (Drosophila)0.583
Pbx1pre B-cell leukemia transcription factor 10.579
Plcg1phospholipase C, gamma 10.574
Zic3zinc finger protein of the cerebellum 30.573
Eya1eyes absent 1 homolog (Drosophila)0.566
Col6a1collagen, type VI, alpha 10.562
Bmp4bone morphogenetic protein 40.548
Gas1growth arrest specific 10.537
Ptenphosphatase and tensin homolog0.536
Efnb1ephrin B10.534
Axin1axin 10.533
Foxc2forkhead box C20.532
Apcadenomatosis polyposis coli0.532
Smad7MAD homolog 7 (Drosophila)0.528
Fzd1frizzled homolog 1 (Drosophila)0.526
Fzd8frizzled homolog 8 (Drosophila)0.520
Grid1glutamate receptor, ionotropic, delta 10.513
Dlg1discs, large homolog 1 (Drosophila)0.511
Amhr2anti-Mullerian hormone type 2 receptor0.509
Pou3f3POU domain, class 3, transcription factor 30.506
Smad1MAD homolog 1 (Drosophila)0.493
Smosmoothened homolog (Drosophila)0.483
Pax9paired box gene 90.482
Gdnfglial cell line derived neurotrophic factor0.468
Pitx3paired-like homeodomain transcription factor 30.462
Gabrb2gamma-aminobutyric acid (GABA) A receptor, subunit beta 20.459
Ephb2Eph receptor B20.451
Arid5bAT rich interactive domain 5B (MRF1-like)0.443
Efna2ephrin A20.440
Ctnnb1catenin (cadherin associated protein), beta 10.424
Pax7paired box gene 70.415
Hoxd13homeobox D130.405
Foxd3forkhead box D30.404
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.402
Hdac7histone deacetylase 70.402
Lhx1LIM homeobox protein 10.395
Wt1Wilms tumor 1 homolog0.392
Dlx1distal-less homeobox 10.384
Hes1hairy and enhancer of split 1 (Drosophila)0.383
Wnt3awingless-related MMTV integration site 3A0.374
Hic1hypermethylated in cancer 10.371
Nos3nitric oxide synthase 3, endothelial cell0.371
Gpc3glypican 30.366
Gdf11growth differentiation factor 110.361
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism