The network for 'negative regulation of cellular response to oxidative stress' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of cellular response to oxidative stress

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
parkparkin0.486
CG8155CG8155 gene product from transcript CG8155-RA0.299
Hsp68Heat shock protein 680.291
Hsp27Heat shock protein 270.287
CG8443CG8443 gene product from transcript CG8443-RA0.242
Pink1PTEN-induced putative kinase 10.179
porinCG6647 gene product from transcript CG6647-RA0.148
Dcr-2Dicer-20.137
jarjaguar0.125
p53CG33336 gene product from transcript CG33336-RB0.098
Hsp22Heat shock protein 220.098
Ppat-DpckBifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase0.087
Hsp26Heat shock protein 260.077
spasspastin0.076
HtrA2CG8464 gene product from transcript CG8464-RA0.072
cdmcadmus0.059
Cf2Chorion factor 20.058
snsinged0.048
Hsp23Heat shock protein 230.046
sopstring of pearls0.045
mofmales absent on the first0.041
NLazNeural Lazarillo0.040
mubmushroom-body expressed0.039
krzkurtz0.037
DJ-1alphaCG6646 gene product from transcript CG6646-RA0.035
CG30410CG30410 gene product from transcript CG30410-RB0.035
kibrakibra ortholog0.034
PargPoly(ADP-ribose) glycohydrolase0.033
HcfHost cell factor0.033
Ino80CG31212 gene product from transcript CG31212-RA0.032
CG8709CG8709 gene product from transcript CG8709-RK0.031
CatCatalase0.030
CG13366CG13366 gene product from transcript CG13366-RA0.028
Mekk1CG7717 gene product from transcript CG7717-RB0.028
ThorCG8846 gene product from transcript CG8846-RA0.028
PpcsPhosphopantothenoylcysteine synthetase0.028
Sin3ACG8815 gene product from transcript CG8815-RC0.026
Vps4Vacuolar protein sorting 40.026
Sod2Superoxide dismutase 2 (Mn)0.026
p120ctnAdherens junction protein p1200.026
DabDisabled0.026
eIF4E-3CG8023 gene product from transcript CG8023-RA0.025
AdarAdenosine deaminase acting on RNA0.025
MTF-1Metal response element-binding Transcription Factor-10.025
Ptp69DProtein tyrosine phosphatase 69D0.024
Ube3aUbiquitin protein ligase E3A0.024
fhfrataxin homolog0.023
Lk6CG17342 gene product from transcript CG17342-RA0.022
kermitCG11546 gene product from transcript CG11546-RB0.022
ZwZwischenferment0.022
nosnanos0.020
Drp1Dynamin related protein 10.020
Nrx-1Neurexin 10.020
LaspCG3849 gene product from transcript CG3849-RB0.020
Letm1CG4589 gene product from transcript CG4589-RB0.018
Hsp70BaHeat-shock-protein-70Ba0.018
rtrotated abdomen0.018
ATP7CG1886 gene product from transcript CG1886-RB0.018
Trap1CG3152 gene product from transcript CG3152-RA0.017
DfdDeformed0.017
SdhBSuccinate dehydrogenase B0.017
betaTub85Dbeta-Tubulin at 85D0.016
Tom34Translocase of outer membrane 340.016
nanarrow abdomen0.016
ImpL2Ecdysone-inducible gene L20.016
TBPHCG10327 gene product from transcript CG10327-RC0.016
mei-P26CG12218 gene product from transcript CG12218-RA0.016
Hsc70-4Heat shock protein cognate 40.016
drddrop dead0.015
MetMethoprene-tolerant0.015
GLazGlial Lazarillo0.015
hiwhighwire0.015
CG1347CG1347 gene product from transcript CG1347-RB0.015
bdgbedraggled0.015
chicoCG5686 gene product from transcript CG5686-RB0.015
msl-2male-specific lethal 20.015
wun2wunen-20.014
mib2mind bomb 20.014
ari-2ariadne 20.014
eggeggless0.014
CG11347CG11347 gene product from transcript CG11347-RE0.014
TazTafazzin0.014
snisniffer0.014
tratransformer0.014
Trim9CG31721 gene product from transcript CG31721-RB0.013
fblfumble0.013
Bacebeta-site APP-cleaving enzyme0.012
l(3)82FdCG32464 gene product from transcript CG32464-RR0.012
amdalpha methyl dopa-resistant0.012
SNF4AgammaSNF4/AMP-activated protein kinase gamma subunit0.012
CG10383CG10383 gene product from transcript CG10383-RA0.012
hppyhappyhour0.012
dj-1betaCG1349 gene product from transcript CG1349-RA0.012
homerCG11324 gene product from transcript CG11324-RC0.012
Atg9Autophagy-specific gene 90.011
CG9866CG9866 gene product from transcript CG9866-RA0.011
msl-1male-specific lethal 10.011
CbyChibby0.011
cln3CG5582 gene product from transcript CG5582-RA0.011
desat1CG5887 gene product from transcript CG5887-RA0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TRIB3tribbles homolog 3 (Drosophila)0.978
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.718
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.693
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.646
ZNF746zinc finger protein 7460.426
NFE2L2nuclear factor (erythroid-derived 2)-like 20.331
KAT2BK(lysine) acetyltransferase 2B0.328
SOD1superoxide dismutase 1, soluble0.319
GAS6growth arrest-specific 60.291
KEAP1kelch-like ECH-associated protein 10.260
PRDX1peroxiredoxin 10.212
METmet proto-oncogene (hepatocyte growth factor receptor)0.207
EGLN1egl nine homolog 1 (C. elegans)0.205
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.175
SQSTM1sequestosome 10.162
VHLvon Hippel-Lindau tumor suppressor0.132
LATlinker for activation of T cells0.113
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.113
SFPQsplicing factor proline/glutamine-rich0.112
TOP1topoisomerase (DNA) I0.110
WBP4WW domain binding protein 4 (formin binding protein 21)0.108
PINK1PTEN induced putative kinase 10.107
FBXO7F-box protein 70.099
HSPB8heat shock 22kDa protein 80.091
FTH1ferritin, heavy polypeptide 10.087
RANBP9RAN binding protein 90.086
PLXNB1plexin B10.084
CRYABcrystallin, alpha B0.081
BAG3BCL2-associated athanogene 30.074
GAB1GRB2-associated binding protein 10.070
APOEapolipoprotein E0.066
EFTUD2elongation factor Tu GTP binding domain containing 20.061
ARNTaryl hydrocarbon receptor nuclear translocator0.053
CSNK1A1casein kinase 1, alpha 10.052
DDIT3DNA-damage-inducible transcript 30.051
DAXXdeath-domain associated protein0.051
CTSDcathepsin D0.049
RUNX1runt-related transcription factor 10.049
MAP2K5mitogen-activated protein kinase kinase 50.046
HGFhepatocyte growth factor (hepapoietin A; scatter factor)0.045
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.041
NONOnon-POU domain containing, octamer-binding0.037
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.036
AHRaryl hydrocarbon receptor0.034
RAB5BRAB5B, member RAS oncogene family0.032
HSF1heat shock transcription factor 10.029
HDAC1histone deacetylase 10.028
HNRNPA1heterogeneous nuclear ribonucleoprotein A10.027
LAMP1lysosomal-associated membrane protein 10.027
DYNLL1dynein, light chain, LC8-type 10.026
FUSfused in sarcoma0.026
PSPC1paraspeckle component 10.025
PMLpromyelocytic leukemia0.025
NFE2L1nuclear factor (erythroid-derived 2)-like 10.024
SMAD2SMAD family member 20.023
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.023
GRNgranulin0.022
SKIv-ski sarcoma viral oncogene homolog (avian)0.022
RCC1regulator of chromosome condensation 10.021
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.021
PTMAprothymosin, alpha0.021
BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 10.021
SDCBPsyndecan binding protein (syntenin)0.021
EIF2S3eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa0.020
APOA1apolipoprotein A-I0.020
APOHapolipoprotein H (beta-2-glycoprotein I)0.020
PRKCZprotein kinase C, zeta0.020
MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)0.019
MAP1Bmicrotubule-associated protein 1B0.019
IFNAR2interferon (alpha, beta and omega) receptor 20.018
TPP1tripeptidyl peptidase I0.018
GAAglucosidase, alpha; acid0.018
SIN3ASIN3 homolog A, transcription regulator (yeast)0.018
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.017
PPIApeptidylprolyl isomerase A (cyclophilin A)0.017
CTSAcathepsin A0.016
CTSL1cathepsin L10.015
PTPRJprotein tyrosine phosphatase, receptor type, J0.015
APLP2amyloid beta (A4) precursor-like protein 20.015
NAMPTnicotinamide phosphoribosyltransferase0.015
ZBED1zinc finger, BED-type containing 10.015
MAP2K6mitogen-activated protein kinase kinase 60.014
PTPN1protein tyrosine phosphatase, non-receptor type 10.014
PACRGPARK2 co-regulated0.014
TOPORStopoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase0.014
OS9osteosarcoma amplified 9, endoplasmic reticulum lectin0.014
CRYAAcrystallin, alpha A0.013
EGLN3egl nine homolog 3 (C. elegans)0.013
HNRNPMheterogeneous nuclear ribonucleoprotein M0.013
RIPK2receptor-interacting serine-threonine kinase 20.013
HSPB7heat shock 27kDa protein family, member 7 (cardiovascular)0.013
BANPBTG3 associated nuclear protein0.013
CTSBcathepsin B0.013
PLD3phospholipase D family, member 30.012
EPAS1endothelial PAS domain protein 10.012
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.012
MAPKAPK2mitogen-activated protein kinase-activated protein kinase 20.012
ETF1eukaryotic translation termination factor 10.012
FOXO3forkhead box O30.012
NBNnibrin0.012
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ppargperoxisome proliferator activated receptor gamma0.585
Rpgrip1lRpgrip1-like0.384
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.324
Trib3tribbles homolog 3 (Drosophila)0.255
Aifm1apoptosis-inducing factor, mitochondrion-associated 10.127
Gab1growth factor receptor bound protein 2-associated protein 10.073
Mitfmicrophthalmia-associated transcription factor0.070
Hif1ahypoxia inducible factor 1, alpha subunit0.067
Edn1endothelin 10.061
Bag3BCL2-associated athanogene 30.058
Nr3c1nuclear receptor subfamily 3, group C, member 10.058
Rb1retinoblastoma 10.055
Itgb1integrin beta 1 (fibronectin receptor beta)0.053
Ghrgrowth hormone receptor0.050
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.047
Cdkn1bcyclin-dependent kinase inhibitor 1B0.047
Rps3ribosomal protein S30.046
Ctnnb1catenin (cadherin associated protein), beta 10.046
FosFBJ osteosarcoma oncogene0.045
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.044
Arntlaryl hydrocarbon receptor nuclear translocator-like0.043
Ep300E1A binding protein p3000.041
Kitlkit ligand0.038
Prdx1peroxiredoxin 10.032
Gpx1glutathione peroxidase 10.031
Mfn2mitofusin 20.031
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.031
Mt2metallothionein 20.030
Stat3signal transducer and activator of transcription 30.026
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.025
Ifngr1interferon gamma receptor 10.025
Cdkn2dcyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)0.024
Ctsdcathepsin D0.023
Kif27kinesin family member 270.022
Ptenphosphatase and tensin homolog0.022
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.022
Kitkit oncogene0.021
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.021
Cav1caveolin 1, caveolae protein0.021
Vhlvon Hippel-Lindau tumor suppressor0.020
Acaa2acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)0.019
Lrp2low density lipoprotein receptor-related protein 20.019
Svaseminal vesicle antigen0.018
Crygdcrystallin, gamma D0.018
Suclg1succinate-CoA ligase, GDP-forming, alpha subunit0.018
Hprthypoxanthine guanine phosphoribosyl transferase0.017
Tcn2transcobalamin 20.017
P4ha2procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide0.017
Il6stinterleukin 6 signal transducer0.016
Park7Parkinson disease (autosomal recessive, early onset) 70.016
Fxyd1FXYD domain-containing ion transport regulator 10.016
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.016
Ctsbcathepsin B0.016
Pgam2phosphoglycerate mutase 20.015
Ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.015
Rps3aribosomal protein S3A0.015
Aldh1a3aldehyde dehydrogenase family 1, subfamily A30.015
Meig1meiosis expressed gene 10.015
Apoeapolipoprotein E0.015
Prnpprion protein0.015
Vegfavascular endothelial growth factor A0.015
Cdh1cadherin 10.015
Mdm2transformed mouse 3T3 cell double minute 20.015
Lystlysosomal trafficking regulator0.014
Tuba4atubulin, alpha 4A0.014
Pax3paired box gene 30.014
0610031J06RikRIKEN cDNA 0610031J06 gene0.014
Adam17a disintegrin and metallopeptidase domain 170.014
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.014
Sema3asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A0.014
Ulk4unc-51-like kinase 4 (C. elegans)0.014
Prrx1paired related homeobox 10.013
Hnrnph1heterogeneous nuclear ribonucleoprotein H10.013
Mkl2MKL/myocardin-like 20.013
Plxnd1plexin D10.013
Sgpl1sphingosine phosphate lyase 10.012
Rpl8ribosomal protein L80.012
Fam164cfamily with sequence similarity 164, member C0.012
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.012
IscuIscU iron-sulfur cluster scaffold homolog (E. coli)0.012
Lipalysosomal acid lipase A0.011
Ece1endothelin converting enzyme 10.011
Idh3bisocitrate dehydrogenase 3 (NAD+) beta0.011
Rarbretinoic acid receptor, beta0.011
Rasgrf2RAS protein-specific guanine nucleotide-releasing factor 20.011
Spp1secreted phosphoprotein 10.011
Gadd45agrowth arrest and DNA-damage-inducible 45 alpha0.011
Casq2calsequestrin 20.011
Cryabcrystallin, alpha B0.011
Cpsf3cleavage and polyadenylation specificity factor 30.011
UgdhUDP-glucose dehydrogenase0.011
Adipor1adiponectin receptor 10.011
Nat1N-acetyl transferase 10.010
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism