The network for 'response to ddt' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to ddt

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals.

NameDescriptionProbabilityFunc Analog Organism
Pttg1pituitary tumor-transforming 10.663
LOC293989cytochrome P450-like0.343
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.332
Cdkn3cyclin-dependent kinase inhibitor 30.225
Cdk1cyclin-dependent kinase 10.213
Top2atopoisomerase (DNA) II alpha0.205
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.195
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.194
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.190
Cdca3cell division cycle associated 30.177
LOC689399hypothetical protein LOC6893990.172
Slco1a1solute carrier organic anion transporter family, member 1a10.150
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.141
Cks2CDC28 protein kinase regulatory subunit 20.120
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.117
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.116
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.114
Traf4af1TRAF4 associated factor 10.100
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.097
TyrobpTyro protein tyrosine kinase binding protein0.097
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.095
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.091
Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 10.078
Sult2a1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.077
Spc25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.075
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.071
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.070
Racgap1Rac GTPase-activating protein 10.067
Dhfrdihydrofolate reductase0.067
RhdRh blood group, D antigen0.066
Kifc1kinesin family member C10.065
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.062
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.061
Cyp2d3cytochrome P450, family 2, subfamily d, polypeptide 30.058
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.054
Otcornithine carbamoyltransferase0.053
Sult1c3sulfotransferase family, cytosolic, 1C, member 30.051
Cyp2c11cytochrome P450, subfamily 2, polypeptide 110.051
Rrm2ribonucleotide reductase M20.050
Il1ainterleukin 1 alpha0.043
Apobapolipoprotein B0.041
Aqp9aquaporin 90.039
Mgst2microsomal glutathione S-transferase 20.038
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.037
Akr1c18aldo-keto reductase family 1, member C180.036
Mettl7bmethyltransferase like 7B0.035
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.035
Ccnb2cyclin B20.034
Slc22a7solute carrier family 22 (organic anion transporter), member 70.034
Kynukynureninase (L-kynurenine hydrolase)0.033
Mug1murinoglobulin 10.032
Olr1082olfactory receptor 10820.032
Ces1ccarboxylesterase 1C0.032
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.031
Sgk2serum/glucocorticoid regulated kinase 20.028
Plk1polo-like kinase 1 (Drosophila)0.028
Ube2cubiquitin-conjugating enzyme E2C0.027
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.027
Cdca8cell division cycle associated 80.023
Hao2hydroxyacid oxidase 2 (long chain)0.023
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.023
Depdc1DEP domain containing 10.023
Cyp4a8cytochrome P450, family 4, subfamily a, polypeptide 80.022
Cd86CD86 molecule0.022
Zfp37zinc finger protein 370.022
Obp3alpha-2u globulin PGCL40.022
Kif2ckinesin family member 2C0.022
Kif18bkinesin family member 18B0.021
KlKlotho0.021
Slco1a4solute carrier organic anion transporter family, member 1a40.021
Akr1c12aldo-keto reductase family 1, member C120.020
Cybbcytochrome b-245, beta polypeptide0.020
Tk1thymidine kinase 1, soluble0.019
Haus4HAUS augmin-like complex, subunit 40.019
A1i3alpha-1-inhibitor III0.018
G6pcglucose-6-phosphatase, catalytic subunit0.018
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.018
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.018
Ust5rintegral membrane transport protein UST5r0.018
Sult2al1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 10.018
Ns5atp9NS5A (hepatitis C virus) transactivated protein 90.017
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.017
Abcc6ATP-binding cassette, subfamily C (CFTR/MRP), member 60.017
Olr59olfactory receptor 590.017
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.016
Nr5a2nuclear receptor subfamily 5, group A, member 20.016
Csf3colony stimulating factor 3 (granulocyte)0.016
Kif22kinesin family member 220.016
Dlgap5discs, large (Drosophila) homolog-associated protein 50.016
Svs3aseminal vesicle secretory protein 3A0.016
Spink1serine peptidase inhibitor, Kazal type 10.016
Cyp2c12cytochrome P450, family 2, subfamily c, polypeptide 120.016
Galnt5UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)0.016
Arl11ADP-ribosylation factor-like 110.015
Slco1b3solute carrier organic anion transporter family, member 1b30.015
Melkmaternal embryonic leucine zipper kinase0.015
Acot12acyl-CoA thioesterase 120.014
Cyp3a9cytochrome P450, family 3, subfamily a, polypeptide 90.014
Pon1paraoxonase 10.014
Sisucrase-isomaltase (alpha-glucosidase)0.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Cyp12a4CG6042 gene product from transcript CG6042-RA0.913
Cyp12d1-pCG30489 gene product from transcript CG30489-RA0.743
Ugt35aUDP-glycosyltransferase 35a0.588
Cyp6a23CG10242 gene product from transcript CG10242-RA0.543
Cyp4ac1CG14032 gene product from transcript CG14032-RA0.442
Cyp6a21CG10247 gene product from transcript CG10247-RA0.284
Cyp12d1-dCG33503 gene product from transcript CG33503-RA0.256
Cyp6a2Cytochrome P450-6a20.213
CG12672CG12672 gene product from transcript CG12672-RA0.174
Cyp12a5CG11821 gene product from transcript CG11821-RA0.161
JhI-26Juvenile hormone-inducible protein 260.138
Cyp6a13CG2397 gene product from transcript CG2397-RA0.121
alpha-Est7alpha-Esterase-70.105
CG6834CG6834 gene product from transcript CG6834-RA0.104
Cyp9b2Cytochrome P450-9b20.098
MetMethoprene-tolerant0.068
Cyp6g1CG8453 gene product from transcript CG8453-RA0.060
dibdisembodied0.059
Cyp4p1Cytochrome P450-4p10.053
Osi6Osiris 60.052
Cyp6w1CG8345 gene product from transcript CG8345-RA0.051
Cyp6a9Cytochrome P450-6a90.047
CG10550CG10550 gene product from transcript CG10550-RB0.042
TotATurandot A0.036
CG3759CG3759 gene product from transcript CG3759-RB0.034
lablabial0.028
CrzCorazonin0.028
CG10562CG10562 gene product from transcript CG10562-RA0.028
sadshadow0.027
nAcRalpha-96Aanicotinic Acetylcholine Receptor alpha 96Aa0.024
CG32687CG32687 gene product from transcript CG32687-RA0.024
sroshroud0.024
spospook0.023
Ctr1ACopper transporter 1A0.023
CG6830CG6830 gene product from transcript CG6830-RA0.023
Cyp28a5CG8864 gene product from transcript CG8864-RA0.023
Cyp12e1CG14680 gene product from transcript CG14680-RC0.022
Est-QEsterase Q0.022
CG15408CG15408 gene product from transcript CG15408-RA0.017
Cyp28d1CG10833 gene product from transcript CG10833-RA0.016
CG12766CG12766 gene product from transcript CG12766-RA0.016
CG16799CG16799 gene product from transcript CG16799-RA0.015
Cyp6g2CG8859 gene product from transcript CG8859-RA0.015
LvpDLarval visceral protein D0.014
CG10560CG10560 gene product from transcript CG10560-RA0.014
Cyp6d4CG12800 gene product from transcript CG12800-RA0.014
Ilp4Insulin-like peptide 40.014
NAAT1Nutrient Amino Acid Transporter 10.014
Adgf-DAdenosine deaminase-related growth factor D0.013
CG3967CG3967 gene product from transcript CG3967-RC0.013
CG33080CG33080 gene product from transcript CG33080-RA0.012
Doc3Dorsocross30.012
Cyp6a8Cytochrome P450-6a80.012
Cyp6a22CG10240 gene product from transcript CG10240-RA0.012
Cyp4e2Cytochrome P450-4e20.011
ST6GalSialyltransferase0.011
CG6283CG6283 gene product from transcript CG6283-RA0.010
CG16965CG16965 gene product from transcript CG16965-RB0.010
Ugt86DdCG6633 gene product from transcript CG6633-RB0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism