The network for 'fc epsilon receptor signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

fc epsilon receptor signaling pathway

A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.

NameDescriptionProbabilityFunc Analog Organism
Folr2folate receptor 2 (fetal)0.230
Cybbcytochrome b-245, beta polypeptide0.099
Ms4a6bmembrane-spanning 4-domains, subfamily A, member 6B0.096
Hpgdshematopoietic prostaglandin D synthase0.051
Cd53Cd53 molecule0.037
Cpa3carboxypeptidase A3, mast cell0.034
Arl11ADP-ribosylation factor-like 110.027
Dnase1l3deoxyribonuclease 1-like 30.026
Ms4a11membrane-spanning 4-domains, subfamily A, member 110.026
Clec4a3C-type lectin domain family 4, member a30.025
Cfhcomplement factor H0.022
C1qbcomplement component 1, q subcomponent, B chain0.021
Tbxas1thromboxane A synthase 1, platelet0.019
Ly86lymphocyte antigen 860.017
Mrc1mannose receptor, C type 10.013
Cd68Cd68 molecule0.013
Bcl2a1dB-cell leukemia/lymphoma 2 related protein A1d0.012
Ctla2acytotoxic T lymphocyte-associated protein 2 alpha0.011
Zcwpw1zinc finger, CW-type with PWWP domain 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.997
Il2rginterleukin 2 receptor, gamma chain0.972
Ptprcprotein tyrosine phosphatase, receptor type, C0.925
TyrobpTYRO protein tyrosine kinase binding protein0.862
Rag1recombination activating gene 10.517
Lyz2lysozyme 20.356
Rag2recombination activating gene 20.338
Latlinker for activation of T cells0.313
TcraT-cell receptor alpha chain0.311
Ccr1chemokine (C-C motif) receptor 10.298
Clec4nC-type lectin domain family 4, member n0.263
Cd247CD247 antigen0.230
C1qbcomplement component 1, q subcomponent, beta polypeptide0.222
Apoeapolipoprotein E0.186
AF251705cDNA sequence AF2517050.162
Msr1macrophage scavenger receptor 10.161
Hcsthematopoietic cell signal transducer0.152
Lcklymphocyte protein tyrosine kinase0.149
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.130
Fcgr3Fc receptor, IgG, low affinity III0.123
Ccl6chemokine (C-C motif) ligand 60.102
Ms4a6dmembrane-spanning 4-domains, subfamily A, member 6D0.088
C3ar1complement component 3a receptor 10.083
Ccl9chemokine (C-C motif) ligand 90.073
Csf1rcolony stimulating factor 1 receptor0.073
Cd68CD68 antigen0.071
Aif1allograft inflammatory factor 10.069
Mpeg1macrophage expressed gene 10.067
Clec4dC-type lectin domain family 4, member d0.066
Ikzf1IKAROS family zinc finger 10.065
Slc11a1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.063
Lilrb3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.062
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.061
Il7rinterleukin 7 receptor0.059
C1qccomplement component 1, q subcomponent, C chain0.058
C1qacomplement component 1, q subcomponent, alpha polypeptide0.056
C5ar1complement component 5a receptor 10.050
Mmp8matrix metallopeptidase 80.048
Calcrlcalcitonin receptor-like0.046
Ifitm6interferon induced transmembrane protein 60.045
Sfpi1SFFV proviral integration 10.045
Clec4a2C-type lectin domain family 4, member a20.041
Selpselectin, platelet0.041
FaslFas ligand (TNF superfamily, member 6)0.040
Pik3cgphosphoinositide-3-kinase, catalytic, gamma polypeptide0.040
Sellselectin, lymphocyte0.040
Cxcr2chemokine (C-X-C motif) receptor 20.039
Clec7aC-type lectin domain family 7, member a0.038
Alox5aparachidonate 5-lipoxygenase activating protein0.036
Tlr7toll-like receptor 70.033
Ncf1neutrophil cytosolic factor 10.032
Fpr2formyl peptide receptor 20.032
Lyz1lysozyme 10.031
Tbxas1thromboxane A synthase 1, platelet0.031
Pf4platelet factor 40.031
Il1binterleukin 1 beta0.031
Ly86lymphocyte antigen 860.031
Klra2killer cell lectin-like receptor, subfamily A, member 20.031
Fpr1formyl peptide receptor 10.031
Inpp5dinositol polyphosphate-5-phosphatase D0.030
BtkBruton agammaglobulinemia tyrosine kinase0.030
Mrc1mannose receptor, C type 10.029
Fcgr1Fc receptor, IgG, high affinity I0.028
Ccr5chemokine (C-C motif) receptor 50.026
Hckhemopoietic cell kinase0.025
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.025
C3complement component 30.025
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.024
Cybbcytochrome b-245, beta polypeptide0.024
Fcgr2bFc receptor, IgG, low affinity IIb0.023
Cd86CD86 antigen0.022
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.022
Ms4a6cmembrane-spanning 4-domains, subfamily A, member 6C0.022
Fcgr4Fc receptor, IgG, low affinity IV0.022
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.022
B2mbeta-2 microglobulin0.021
Tlr4toll-like receptor 40.020
Csf2rb2colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)0.020
Cr2complement receptor 20.019
Ccl3chemokine (C-C motif) ligand 30.019
Lair1leukocyte-associated Ig-like receptor 10.019
Zap70zeta-chain (TCR) associated protein kinase0.019
Ccl12chemokine (C-C motif) ligand 120.018
Fgd3FYVE, RhoGEF and PH domain containing 30.018
FasFas (TNF receptor superfamily member 6)0.018
Slpisecretory leukocyte peptidase inhibitor0.017
Cd19CD19 antigen0.017
Il2interleukin 20.017
Ctsscathepsin S0.017
Ncr1natural cytotoxicity triggering receptor 10.017
Folr2folate receptor 2 (fetal)0.017
Pilrapaired immunoglobin-like type 2 receptor alpha0.017
Klrk1killer cell lectin-like receptor subfamily K, member 10.016
Cd180CD180 antigen0.016
Lcp2lymphocyte cytosolic protein 20.016
Itgamintegrin alpha M0.016
Tnftumor necrosis factor0.016
Myo1fmyosin IF0.016
Igsf6immunoglobulin superfamily, member 60.016
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism