The network for 'extracellular fibril organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

extracellular fibril organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of extracellular fibrils, extracellular matrix material consisting of polysaccharides and/or proteins.

NameDescriptionProbabilityFunc Analog Organism
Col1a2collagen, type I, alpha 20.993
Col1a1collagen, type I, alpha 10.974
Col5a2collagen, type V, alpha 20.525
Loxl1lysyl oxidase-like 10.352
Fbn1fibrillin 10.272
Col14a1collagen, type XIV, alpha 10.253
Col3a1collagen, type III, alpha 10.243
Ccdc80coiled-coil domain containing 800.213
Sparcsecreted protein, acidic, cysteine-rich (osteonectin)0.208
Mfap4microfibrillar-associated protein 40.168
Fstl1follistatin-like 10.145
Pcolceprocollagen C-endopeptidase enhancer0.125
Col5a1collagen, type V, alpha 10.121
Apoeapolipoprotein E0.110
Postnperiostin, osteoblast specific factor0.109
Col15a1collagen, type XV, alpha 10.087
Col6a2collagen, type VI, alpha 20.070
Col4a1collagen, type IV, alpha 10.060
LOC686539similar to immunoglobulin superfamily containing leucine-rich repeat0.048
Lama2laminin, alpha 20.033
Fndc1fibronectin type III domain containing 10.029
Rcn3reticulocalbin 3, EF-hand calcium binding domain0.027
Tpt1tumor protein, translationally-controlled 10.027
Maged2melanoma antigen, family D, 20.024
Timp2TIMP metallopeptidase inhibitor 20.022
Ap2m1adaptor-related protein complex 2, mu 1 subunit0.021
Nid2nidogen 20.020
Col12a1collagen, type XII, alpha 10.019
Cpzcarboxypeptidase Z0.019
Rabac1Rab acceptor 1 (prenylated)0.016
Ltbp4latent transforming growth factor beta binding protein 40.015
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.015
Calm1calmodulin 10.015
Pxdnperoxidasin homolog (Drosophila)0.014
Actg1actin, gamma 10.014
Myl9myosin, light chain 9, regulatory0.013
Igfbp7insulin-like growth factor binding protein 70.012
Fkbp9FK506 binding protein 90.012
Praf2PRA1 domain family, member 20.011
Cox8acytochrome c oxidase subunit VIIIa0.010
Leprel2leprecan-like 20.010
Srpxsushi-repeat-containing protein, X-linked0.010
Igfbp6insulin-like growth factor binding protein 60.010
Mfap2microfibrillar-associated protein 20.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.065
otx2orthodenticle homolog 20.039
meis2.1myeloid ecotropic viral integration site 2.10.030
foxb1.1forkhead box B1.10.030
pax6bpaired box gene 6b0.029
sox2SRY-box containing gene 20.027
epha4aeph receptor A4a0.027
dbx1adeveloping brain homeobox 1a0.020
pcnaproliferating cell nuclear antigen0.019
sox3SRY-box containing gene 30.018
rx3retinal homeobox gene 30.017
otx1aorthodenticle homolog 1a0.017
irx3airoquois homeobox protein 3a0.016
meis1myeloid ecotropic viral integration 10.014
sox19aSRY-box containing gene 19a0.014
dlx3bdistal-less homeobox gene 3b0.014
otx1borthodenticle homolog 1b0.013
foxb1.2forkhead box B1.20.013
zic1zic family member 1 (odd-paired homolog, Drosophila)0.013
olig2oligodendrocyte lineage transcription factor 20.012
gbx2gastrulation brain homeo box 20.011
hoxb1bhomeo box B1b0.011
flhfloating head0.011
ca2carbonic anhydrase II0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
COL1A2collagen, type I, alpha 20.728
COL4A1collagen, type IV, alpha 10.628
TEKTEK tyrosine kinase, endothelial0.610
COL1A1collagen, type I, alpha 10.591
COL3A1collagen, type III, alpha 10.507
COL5A2collagen, type V, alpha 20.256
DDR2discoidin domain receptor tyrosine kinase 20.118
COL5A1collagen, type V, alpha 10.111
SPARCsecreted protein, acidic, cysteine-rich (osteonectin)0.104
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.069
LOXlysyl oxidase0.066
FBN1fibrillin 10.054
COL6A1collagen, type VI, alpha 10.051
PARVAparvin, alpha0.042
FGAfibrinogen alpha chain0.026
MTORmechanistic target of rapamycin (serine/threonine kinase)0.026
FGGfibrinogen gamma chain0.023
ACVR1Bactivin A receptor, type IB0.017
POSTNperiostin, osteoblast specific factor0.014
MXRA5matrix-remodelling associated 50.012
COL4A2collagen, type IV, alpha 20.012
THBS1thrombospondin 10.012
THY1Thy-1 cell surface antigen0.011
COL6A3collagen, type VI, alpha 30.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Col3a1collagen, type III, alpha 10.635
Col1a2collagen, type I, alpha 20.621
Col5a2collagen, type V, alpha 20.587
Col6a2collagen, type VI, alpha 20.425
Col1a1collagen, type I, alpha 10.340
Col6a1collagen, type VI, alpha 10.330
Col6a3collagen, type VI, alpha 30.269
Pcolceprocollagen C-endopeptidase enhancer protein0.173
Col15a1collagen, type XV, alpha 10.159
Col5a1collagen, type V, alpha 10.134
Col14a1collagen, type XIV, alpha 10.116
Col4a1collagen, type IV, alpha 10.109
Sparcsecreted acidic cysteine rich glycoprotein0.090
Postnperiostin, osteoblast specific factor0.080
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.074
Anxa5annexin A50.065
Ccdc80coiled-coil domain containing 800.058
Nid1nidogen 10.054
Thbs2thrombospondin 20.049
Parvaparvin, alpha0.049
Col4a2collagen, type IV, alpha 20.049
Fstl1follistatin-like 10.049
Fbln2fibulin 20.045
Capns1calpain, small subunit 10.038
Aoc3amine oxidase, copper containing 30.038
Ctskcathepsin K0.037
Thbs1thrombospondin 10.036
Fbn1fibrillin 10.031
Rsu1Ras suppressor protein 10.031
Tmem45atransmembrane protein 45a0.029
Fndc1fibronectin type III domain containing 10.022
Itgb1integrin beta 1 (fibronectin receptor beta)0.022
Loxlysyl oxidase0.021
Mfap5microfibrillar associated protein 50.021
Myadmmyeloid-associated differentiation marker0.020
Pltpphospholipid transfer protein0.020
S100a11S100 calcium binding protein A11 (calgizzarin)0.019
Stab1stabilin 10.019
Lama4laminin, alpha 40.019
Wisp1WNT1 inducible signaling pathway protein 10.019
S100a6S100 calcium binding protein A6 (calcyclin)0.018
MrgprfMAS-related GPR, member F0.018
Loxl1lysyl oxidase-like 10.017
Gpr133G protein-coupled receptor 1330.016
Kdelr3KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 30.016
Srpxsushi-repeat-containing protein0.015
Cd99CD99 antigen0.015
Tfpi2tissue factor pathway inhibitor 20.015
Bmp1bone morphogenetic protein 10.015
Clec3bC-type lectin domain family 3, member b0.015
Svep1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 10.014
Actn4actinin alpha 40.014
Fam114a1family with sequence similarity 114, member A10.014
Cd151CD151 antigen0.014
Ptk2PTK2 protein tyrosine kinase 20.014
Kctd10potassium channel tetramerisation domain containing 100.014
Col8a1collagen, type VIII, alpha 10.013
Mfap4microfibrillar-associated protein 40.013
Cdh11cadherin 110.012
Cd34CD34 antigen0.012
Lama5laminin, alpha 50.012
Tnctenascin C0.012
Adamts2a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20.012
Nnmtnicotinamide N-methyltransferase0.011
Tmsb4xthymosin, beta 4, X chromosome0.011
Islrimmunoglobulin superfamily containing leucine-rich repeat0.011
Naalad2N-acetylated alpha-linked acidic dipeptidase 20.011
Cdh5cadherin 50.010
Cpxm1carboxypeptidase X 1 (M14 family)0.010
Gm10393predicted gene 103930.010
Fapfibroblast activation protein0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism