The network for 'positive regulation of triglyceride metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of triglyceride metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.

NameDescriptionProbabilityFunc Analog Organism
Fasnfatty acid synthase0.466
Gpd1glycerol-3-phosphate dehydrogenase 1 (soluble)0.268
Akt2v-akt murine thymoma viral oncogene homolog 20.236
Ube2cubiquitin-conjugating enzyme E2C0.225
Ghrgrowth hormone receptor0.191
Gna12guanine nucleotide binding protein (G protein) alpha 120.158
Top2atopoisomerase (DNA) II alpha0.126
Cd36CD36 molecule (thrombospondin receptor)0.108
Catcatalase0.106
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.105
Cks2CDC28 protein kinase regulatory subunit 20.099
Lpcat3lysophosphatidylcholine acyltransferase 30.073
Acacaacetyl-coenzyme A carboxylase alpha0.068
Stx2syntaxin 20.068
Syngr2synaptogyrin 20.068
Akr1c14aldo-keto reductase family 1, member C140.056
Pdia4protein disulfide isomerase family A, member 40.053
Srebf1sterol regulatory element binding transcription factor 10.050
Acot2acyl-CoA thioesterase 20.043
Ccnb1cyclin B10.040
RGD1564614similar to complement factor H-related protein0.038
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.035
Rab1bRAB1B, member RAS oncogene family0.033
Cdkn3cyclin-dependent kinase inhibitor 30.031
Spc25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.030
Racgap1Rac GTPase-activating protein 10.029
Nusap1nucleolar and spindle associated protein 10.028
Kifc1kinesin family member C10.028
Dgat2diacylglycerol O-acyltransferase homolog 2 (mouse)0.028
Clcn7chloride channel 70.027
Rxraretinoid X receptor alpha0.027
Pdk2pyruvate dehydrogenase kinase, isozyme 20.026
Nuf2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.026
Aldh6a1aldehyde dehydrogenase 6 family, member A10.026
Etfdhelectron-transferring-flavoprotein dehydrogenase0.025
Mcm6minichromosome maintenance complex component 60.025
Rrm2ribonucleotide reductase M20.024
IlvblilvB (bacterial acetolactate synthase)-like0.024
Pyglphosphorylase, glycogen, liver0.024
Fabp1fatty acid binding protein 1, liver0.024
Vamp1vesicle-associated membrane protein 10.023
Slc25a10solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 100.022
Lsslanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)0.020
Lactblactamase, beta0.020
Aurkbaurora kinase B0.020
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.019
Thrspthyroid hormone responsive0.019
Ect2epithelial cell transforming sequence 2 oncogene0.018
Acox1acyl-Coenzyme A oxidase 1, palmitoyl0.017
Ccnb2cyclin B20.017
Depdc1DEP domain containing 10.017
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.017
PbkPDZ binding kinase0.017
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.017
Ehhadhenoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase0.017
Adhfe1alcohol dehydrogenase, iron containing, 10.016
Casp7caspase 70.016
Ideinsulin degrading enzyme0.016
Pcyt1aphosphate cytidylyltransferase 1, choline, alpha0.015
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.015
Hadhhydroxyacyl-Coenzyme A dehydrogenase0.015
Baatbile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)0.015
Traf4af1TRAF4 associated factor 10.015
Lig3ligase III, DNA, ATP-dependent0.014
Tom1target of myb1 homolog (chicken)0.014
RGD1305347similar to RIKEN cDNA 2610528J110.014
Scarb1scavenger receptor class B, member 10.014
Mocs1molybdenum cofactor synthesis 10.014
Npepl1aminopeptidase-like 10.014
Ces1dcarboxylesterase 1D0.014
Acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.013
Retsatretinol saturase (all trans retinol 13,14 reductase)0.013
Slc30a1solute carrier family 30 (zinc transporter), member 10.013
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.013
Aldh1l1aldehyde dehydrogenase 1 family, member L10.013
GchfrGTP cyclohydrolase I feedback regulator0.013
Dgat1diacylglycerol O-acyltransferase homolog 1 (mouse)0.013
Myo1dmyosin ID0.013
Mosc1MOCO sulphurase C-terminal domain containing 10.012
Tp53i13tumor protein p53 inducible protein 130.012
Ns5atp9NS5A (hepatitis C virus) transactivated protein 90.012
LOC259246alpha-2u globulin PGCL10.012
Scd1stearoyl-Coenzyme A desaturase 10.012
Chpt1choline phosphotransferase 10.012
Rab27aRAB27A, member RAS oncogene family0.012
Cyth1cytohesin 10.012
F2coagulation factor II (thrombin)0.012
Melkmaternal embryonic leucine zipper kinase0.012
Mki67antigen identified by monoclonal antibody Ki-670.012
RGD1311756similar to hypothetical protein FLJ209500.012
Nat1N-acetyltransferase 10.012
Prc1protein regulator of cytokinesis 10.011
Amy1aamylase, alpha 1A (salivary)0.011
Tcfe2atranscription factor E2a0.011
Cyb5r3cytochrome b5 reductase 30.011
Pemtphosphatidylethanolamine N-methyltransferase0.011
RGD1308772similar to KIAA0564 protein0.011
Agpat21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)0.011
Dhcr77-dehydrocholesterol reductase0.011
Cyp51cytochrome P450, family 510.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDK2cyclin-dependent kinase 21.000
CCNA2cyclin A20.728
DHCR77-dehydrocholesterol reductase0.717
CCNE1cyclin E10.679
APOEapolipoprotein E0.426
UHRF2ubiquitin-like with PHD and ring finger domains 20.258
CCNB2cyclin B20.219
CDT1chromatin licensing and DNA replication factor 10.200
MED15mediator complex subunit 150.167
HPhaptoglobin0.166
SMPD1sphingomyelin phosphodiesterase 1, acid lysosomal0.163
APOC1apolipoprotein C-I0.141
CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 10.131
SKP2S-phase kinase-associated protein 2 (p45)0.124
CTDNEP1CTD nuclear envelope phosphatase 10.106
CCNB1cyclin B10.091
ALBalbumin0.086
CREBBPCREB binding protein0.085
TMEM188transmembrane protein 1880.084
ARandrogen receptor0.080
RARAretinoic acid receptor, alpha0.075
SREBF2sterol regulatory element binding transcription factor 20.075
KAT2BK(lysine) acetyltransferase 2B0.072
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.066
APOC3apolipoprotein C-III0.058
MSTO1misato homolog 1 (Drosophila)0.046
APOA1apolipoprotein A-I0.046
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.045
NCOA1nuclear receptor coactivator 10.043
DHCR2424-dehydrocholesterol reductase0.039
APOA2apolipoprotein A-II0.037
INSIG1insulin induced gene 10.035
JUPjunction plakoglobin0.030
UBE2R2ubiquitin-conjugating enzyme E2R 20.028
LCATlecithin-cholesterol acyltransferase0.028
FANCAFanconi anemia, complementation group A0.028
NCOA6nuclear receptor coactivator 60.027
NCAPHnon-SMC condensin I complex, subunit H0.023
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.023
PCSK9proprotein convertase subtilisin/kexin type 90.022
CDK1cyclin-dependent kinase 10.022
TNFRSF10Ctumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain0.020
FOXO3forkhead box O30.017
HIC1hypermethylated in cancer 10.017
FOXO1forkhead box O10.015
NCOA2nuclear receptor coactivator 20.014
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.014
FGAfibrinogen alpha chain0.014
TNIKTRAF2 and NCK interacting kinase0.014
MVKmevalonate kinase0.013
NCAPD2non-SMC condensin I complex, subunit D20.012
TXNDC2thioredoxin domain containing 2 (spermatozoa)0.012
SKP1S-phase kinase-associated protein 10.012
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.012
SCDstearoyl-CoA desaturase (delta-9-desaturase)0.011
PDIA3protein disulfide isomerase family A, member 30.011
EDF1endothelial differentiation-related factor 10.011
APOA4apolipoprotein A-IV0.010
GLIS2GLIS family zinc finger 20.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Apoeapolipoprotein E0.999
Abhd5abhydrolase domain containing 50.999
Cav1caveolin 1, caveolae protein0.998
Ppargperoxisome proliferator activated receptor gamma0.998
Pnpla2patatin-like phospholipase domain containing 20.998
Ghrgrowth hormone receptor0.975
Lepleptin0.970
Lpin1lipin 10.966
Dab1disabled homolog 1 (Drosophila)0.943
Lef1lymphoid enhancer binding factor 10.901
Lrp1low density lipoprotein receptor-related protein 10.891
Cideccell death-inducing DFFA-like effector c0.823
Tcf7transcription factor 7, T-cell specific0.676
Npc1Niemann Pick type C10.595
Scd1stearoyl-Coenzyme A desaturase 10.579
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.516
Plin5perilipin 50.484
Nos3nitric oxide synthase 3, endothelial cell0.288
Ldlrlow density lipoprotein receptor0.246
Lipelipase, hormone sensitive0.235
Cdkn1bcyclin-dependent kinase inhibitor 1B0.215
Ccne1cyclin E10.213
Bscl2Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)0.206
Wasf2WAS protein family, member 20.173
Lcatlecithin cholesterol acyltransferase0.154
Dhcr77-dehydrocholesterol reductase0.139
Lmf1lipase maturation factor 10.131
Ncoa3nuclear receptor coactivator 30.131
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.128
Ccna2cyclin A20.127
Sqlesqualene epoxidase0.125
Adrb3adrenergic receptor, beta 30.116
Plin1perilipin 10.109
Il1r1interleukin 1 receptor, type I0.105
Flt1FMS-like tyrosine kinase 10.101
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.084
Arandrogen receptor0.083
Relnreelin0.081
Agpat21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)0.079
Lpllipoprotein lipase0.077
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.075
Mstnmyostatin0.071
Srfserum response factor0.070
Fasnfatty acid synthase0.065
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.061
Gpd2glycerol phosphate dehydrogenase 2, mitochondrial0.054
Lsslanosterol synthase0.052
Cyp51cytochrome P450, family 510.046
Adipoqadiponectin, C1Q and collagen domain containing0.044
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.043
Nr1h3nuclear receptor subfamily 1, group H, member 30.038
Sc4molsterol-C4-methyl oxidase-like0.036
Psen1presenilin 10.035
Bckdhabranched chain ketoacid dehydrogenase E1, alpha polypeptide0.034
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 10.034
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.033
H1histocompatibility 10.031
Leprleptin receptor0.031
AclyATP citrate lyase0.030
Otx2orthodenticle homolog 2 (Drosophila)0.027
Slc12a6solute carrier family 12, member 60.026
Nfe2l2nuclear factor, erythroid derived 2, like 20.024
Ctnnb1catenin (cadherin associated protein), beta 10.023
Klf15Kruppel-like factor 150.023
Mvdmevalonate (diphospho) decarboxylase0.022
Mknk2MAP kinase-interacting serine/threonine kinase 20.020
Ccnd1cyclin D10.020
Plin2perilipin 20.020
Adrb2adrenergic receptor, beta 20.019
Fabp4fatty acid binding protein 4, adipocyte0.019
Ccl2chemokine (C-C motif) ligand 20.018
Ppap2bphosphatidic acid phosphatase type 2B0.017
Tbx3T-box 30.016
Efemp2epidermal growth factor-containing fibulin-like extracellular matrix protein 20.016
Stat3signal transducer and activator of transcription 30.015
Hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 70.015
Hist1h1ahistone cluster 1, H1a0.015
Gjb2gap junction protein, beta 20.015
PorP450 (cytochrome) oxidoreductase0.014
Ccnb1cyclin B10.014
Aacsacetoacetyl-CoA synthetase0.013
Adrb1adrenergic receptor, beta 10.013
Hsd11b1hydroxysteroid 11-beta dehydrogenase 10.013
Prlrprolactin receptor0.012
Irs1insulin receptor substrate 10.012
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.012
Bcl2B-cell leukemia/lymphoma 20.012
Kiss1KiSS-1 metastasis-suppressor0.012
Slc25a1solute carrier family 25 (mitochondrial carrier, citrate transporter), member 10.011
Axin2axin20.011
Tlr4toll-like receptor 40.011
Agtr2angiotensin II receptor, type 20.011
Bglapbone gamma carboxyglutamate protein0.011
Cd36CD36 antigen0.011
Fdpsfarnesyl diphosphate synthetase0.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
UBI4Ubi4p0.013