The network for 'lipid biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

NameDescriptionProbabilityFunc Analog Organism
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)1.000
Cyp51cytochrome P450, family 511.000
Sc4molsterol-C4-methyl oxidase-like0.998
Idi1isopentenyl-diphosphate delta isomerase 10.997
Fdft1farnesyl diphosphate farnesyl transferase 10.995
Acat3acetyl-Coenzyme A acetyltransferase 30.994
Fasnfatty acid synthase0.990
Lsslanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)0.971
AclyATP citrate lyase0.968
Sqlesqualene epoxidase0.966
Fdpsfarnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)0.929
Dhcr77-dehydrocholesterol reductase0.926
Cd36CD36 molecule (thrombospondin receptor)0.926
Insig1insulin induced gene 10.868
Hmgcr3-hydroxy-3-methylglutaryl-Coenzyme A reductase0.776
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.716
Dhcr2424-dehydrocholesterol reductase0.681
Fads1fatty acid desaturase 10.604
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.585
Clca4chloride channel accessory 40.527
Vimvimentin0.508
Sc5dlsterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like0.464
Hsd17b7hydroxysteroid (17-beta) dehydrogenase 70.410
Irs1insulin receptor substrate 10.407
NsdhlNAD(P) dependent steroid dehydrogenase-like0.379
S100a9S100 calcium binding protein A90.360
Scd1stearoyl-Coenzyme A desaturase 10.346
Tkttransketolase0.344
Hsd3b1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 10.333
Idh1isocitrate dehydrogenase 1 (NADP+), soluble0.331
RGD1305689similar to DNA segment, Chr 14, ERATO Doi 449, expressed0.328
Pla2g2cphospholipase A2, group IIC0.327
Pnpla2patatin-like phospholipase domain containing 20.319
Acss2acyl-CoA synthetase short-chain family member 20.312
Agxtalanine-glyoxylate aminotransferase0.310
DbpD site of albumin promoter (albumin D-box) binding protein0.304
Prl8a2prolactin family 8, subfamily a, member 20.295
Anxa2annexin A20.294
Cyp21a1cytochrome P450, family 21, subfamily a, polypeptide 10.291
Acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.287
Gzmbgranzyme B0.284
Fads2fatty acid desaturase 20.271
Olr1696olfactory receptor 16960.269
Anxa5annexin A50.269
Orm1orosomucoid 10.263
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.262
Etfdhelectron-transferring-flavoprotein dehydrogenase0.249
Rhox5reproductive homeobox 50.248
Lgals4lectin, galactoside-binding, soluble, 40.247
Pcyt2phosphate cytidylyltransferase 2, ethanolamine0.246
Kcne1potassium voltage-gated channel, Isk-related family, member 10.245
Galnt5UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)0.244
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.243
Pth2rparathyroid hormone 2 receptor0.239
Apba3amyloid beta (A4) precursor protein-binding, family A, member 30.239
RGD1566083similar to hypothetical protein MGC240470.237
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.236
Nr5a2nuclear receptor subfamily 5, group A, member 20.235
Aqp9aquaporin 90.234
Pyglphosphorylase, glycogen, liver0.233
Adam2ADAM metallopeptidase domain 20.228
Gucy2dguanylate cyclase 2d0.226
Pxmp2peroxisomal membrane protein 20.224
Adipor2adiponectin receptor 20.222
Prlrprolactin receptor0.218
Pnlippancreatic lipase0.218
Cfdcomplement factor D (adipsin)0.217
Tmem97transmembrane protein 970.216
Mrgprx3MAS-related GPR, member X30.215
Mmp8matrix metallopeptidase 80.213
Cyp3a2cytochrome P450, family 3, subfamily a, polypeptide 20.206
Acacaacetyl-coenzyme A carboxylase alpha0.203
Kcnh5potassium voltage-gated channel, subfamily H (eag-related), member 50.202
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.199
Slc25a1solute carrier family 25 (mitochondrial carrier, citrate transporter), member 10.197
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.196
Cpt1bcarnitine palmitoyltransferase 1b, muscle0.195
Vcsa2variable coding sequence A20.195
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.193
Agtr1bangiotensin II receptor, type 1b0.191
B4galt1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 10.191
Rdh7retinol dehydrogenase 70.190
Hoxd9homeo box D90.189
Scgb1a1secretoglobin, family 1A, member 1 (uteroglobin)0.188
Sult2a1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.188
Cd40lgCD40 ligand0.187
Pipprolactin induced protein0.186
Slc22a3solute carrier family 22 (extraneuronal monoamine transporter), member 30.178
Fam108b1family with sequence similarity 108, member B10.177
Serpina3mserine (or cysteine) proteinase inhibitor, clade A, member 3M0.177
Citcitron0.177
Hcrtr2hypocretin (orexin) receptor 20.177
Tm7sf2transmembrane 7 superfamily member 20.175
S100a11S100 calcium binding protein A11 (calizzarin)0.174
Slc8a1solute carrier family 8 (sodium/calcium exchanger), member 10.174
Nr0b2nuclear receptor subfamily 0, group B, member 20.173
Acsl1acyl-CoA synthetase long-chain family member 10.173
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.172
Aqp7aquaporin 70.172
Fam126bfamily with sequence similarity 126, member B0.170
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
elo-2Protein ELO-20.907
pmt-1Protein PMT-10.831
fat-4Protein FAT-40.700
elo-6Protein ELO-60.686
fat-2Protein FAT-20.547
sur-5Protein SUR-50.526
fat-6Protein FAT-60.502
fat-1Protein FAT-10.484
elo-5Protein ELO-50.478
itr-1Protein ITR-10.422
fat-3Protein FAT-30.358
brp-1Protein BRP-10.254
cpz-2Protein CPZ-20.237
elo-1Protein ELO-10.234
pes-9Protein PES-90.222
CELE_Y43F8C.13Protein Y43F8C.130.215
tag-320Protein TAG-3200.209
hpo-13Protein HPO-130.189
mpk-1Protein MPK-10.188
sptl-1Protein SPTL-10.186
hpd-1Protein HPD-10.173
let-767Protein LET-7670.171
bar-1Protein BAR-10.165
pod-2Protein POD-20.162
pho-1Protein PHO-10.156
hpo-8Protein HPO-80.151
gspd-1Protein GSPD-10.150
lmp-1Protein LMP-10.138
CELE_Y53C10A.5Protein Y53C10A.50.137
R02F2.5Protein R02F2.50.137
dct-18Protein DCT-180.132
nhr-68Protein NHR-680.127
gana-1Protein GANA-10.126
cept-1Protein CEPT-10.123
F32A5.3Protein F32A5.30.122
sma-6Protein SMA-60.112
ran-2Protein RAN-20.110
tre-1Protein TRE-10.110
let-23Protein LET-230.103
dhs-4Protein DHS-40.102
aqp-10Protein AQP-100.099
CELE_F23H12.5Protein F23H12.50.097
CELE_ZK1307.8Protein ZK1307.80.093
acs-14Protein ACS-140.089
acy-3Protein ACY-30.084
ufd-2Protein UFD-20.084
C48B4.1Protein C48B4.10.084
CELE_F17C11.6Protein F17C11.60.083
erd-2Protein ERD-20.083
lbp-3Protein LBP-30.081
F13E6.5Protein F13E6.50.080
sptl-2Protein SPTL-20.079
F48E8.3Protein F48E8.30.079
raga-1Protein RAGA-10.078
tpxl-1Protein TPXL-10.077
pkg-1Protein PKG-10.077
cysl-3Protein CYSL-30.076
CELE_ZK1320.2Protein ZK1320.20.074
F09E5.11Protein F09E5.110.074
maoc-1Protein MAOC-10.072
sem-5Protein SEM-50.071
K02D7.1Protein K02D7.10.070
T03G11.4Protein T03G11.40.068
K11H12.8Protein K11H12.80.068
T28D9.3Protein T28D9.30.067
R11A8.5Protein R11A8.50.064
cyp-35C1Protein CYP-35C10.063
C48A7.2Protein C48A7.20.062
C03A3.2Protein C03A3.20.061
nhr-64Protein NHR-640.061
egl-8Protein EGL-80.061
R10H10.3Protein R10H10.30.058
ugt-25Protein UGT-250.057
tsp-14Protein TSP-140.057
cdf-1Protein CDF-10.056
ethe-1Protein ETHE-10.056
CELE_C29F7.2Protein C29F7.20.055
hmgs-1Protein HMGS-10.054
lact-3Protein LACT-30.053
CELE_T01B11.2Protein T01B11.20.053
exc-7Protein EXC-70.053
F46H5.7Protein F46H5.70.053
rskn-1Protein RSKN-10.053
K10D6.4Protein K10D6.40.052
C11E4.6Protein C11E4.60.051
cka-2Protein CKA-20.051
C34D10.2Protein C34D10.20.050
xpo-3Protein XPO-30.049
sptl-3Protein SPTL-30.049
T23F11.1Protein T23F11.10.049
osm-11Protein OSM-110.048
cyp-43A1Protein CYP-43A10.048
CELE_C49C3.4Protein C49C3.40.048
gob-1Protein GOB-10.048
F22F7.1Protein F22F7.10.047
acl-7Protein ACL-70.047
ugt-23Protein UGT-230.046
prk-1Protein PRK-10.045
vha-14Protein VHA-140.045
spp-8Protein SPP-80.044
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.505
fgf3fibroblast growth factor 30.234
cyp11a1cytochrome P450, subfamily XIA, polypeptide 10.216
apoa4apolipoprotein A-IV0.207
bmp2bbone morphogenetic protein 2b0.191
lppLIM domain containing preferred translocation partner in lipoma0.186
ptgs1prostaglandin-endoperoxide synthase 10.161
esr2bestrogen receptor 2b0.157
ocrloculocerebrorenal syndrome of Lowe0.146
cldn2claudin 20.146
mtpmicrosomal triglyceride transfer protein0.143
sox9bSRY-box containing gene 9b0.138
sox9aSRY-box containing gene 9a0.138
gata6GATA-binding protein 60.129
ptgs2aprostaglandin-endoperoxide synthase 2a0.127
inhainhibin, alpha0.121
cyp1acytochrome P450, family 1, subfamily A0.106
igf1rainsulin-like growth factor 1a receptor0.100
fgfrl1bfibroblast growth factor receptor-like 1b0.099
runx2brunt-related transcription factor 2b0.098
fabp2fatty acid binding protein 2, intestinal0.090
lass2LAG1 homolog, ceramide synthase 2 (S. cerevisiae)0.090
cyp2y3cytochrome P450, family 2, subfamily Y, polypeptide 30.089
cldn1claudin 10.088
lamc1laminin, gamma 10.081
lhcgrluteinizing hormone/choriogonadotropin receptor0.080
atp2b2ATPase, Ca++ transporting, plasma membrane 20.080
hsd17b3hydroxysteroid (17-beta) dehydrogenase 30.078
hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)0.076
nkx2.3NK2 transcription factor related 30.074
pbx1apre-B-cell leukemia transcription factor 1a0.072
cdx1acaudal type homeo box transcription factor 1 a0.069
col11a1acollagen, type XI, alpha 1a0.065
epas1bendothelial PAS domain protein 1b0.063
rbp2aretinol binding protein 2a, cellular0.062
plcg1phospholipase C, gamma 10.062
hsd17b12bhydroxysteroid (17-beta) dehydrogenase 12b0.061
fabp10afatty acid binding protein 10a, liver basic0.059
pvalb7parvalbumin 70.058
ptgdsprostaglandin D2 synthase0.058
mst1macrophage stimulating 1 (hepatocyte growth factor-like)0.057
fgfr2fibroblast growth factor receptor 20.054
hsd17b12ahydroxysteroid (17-beta) dehydrogenase 12a0.053
hnf4ahepatocyte nuclear factor 4, alpha0.050
foxa1forkhead box A10.049
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.048
fstafollistatin a0.048
frem3Fras1 related extracellular matrix 30.048
mstnbmyostatin b0.047
entpd1ectonucleoside triphosphate diphosphohydrolase 10.047
vtg1vitellogenin 10.046
slc8a1bsolute carrier family 8 (sodium/calcium exchanger), member 1b0.045
hsd17b1hydroxysteroid (17-beta) dehydrogenase 10.045
tm4sf4transmembrane 4 L six family member 40.044
ip6k2inositol hexaphosphate kinase 20.044
pomt1protein-O-mannosyltransferase 10.044
si:dkeyp-110g5.2si:dkeyp-110g5.20.042
jag1bjagged 1b0.041
inhbaainhibin, beta Aa0.040
gfergrowth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)0.040
atp1a1a.3ATPase, Na+/K+ transporting, alpha 1a.3 polypeptide0.039
vmhcventricular myosin heavy chain0.039
slc37a4asolute carrier family 37 (glucose-6-phosphate transporter), member 4a0.038
elovl7bELOVL family member 7, elongation of long chain fatty acids (yeast) b0.038
cldnbclaudin b0.038
dzip1DAZ interacting protein 10.037
arandrogen receptor0.037
cyp19a1acytochrome P450, family 19, subfamily A, polypeptide 1a0.037
igf1rbinsulin-like growth factor 1b receptor0.036
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.036
c3bcomplement component c3b0.035
rnf128aring finger protein 128a0.035
zgc:161979zgc:1619790.034
tyrp1btyrosinase-related protein 1b0.034
si:ch211-93f2.1si:ch211-93f2.10.034
hnf1baHNF1 homeobox Ba0.034
fetubfetuin B0.033
mibmind bomb0.033
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.033
runx2arunt-related transcription factor 2a0.032
paqr7bprogestin and adipoQ receptor family member VII, b0.032
slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.032
slc6a11solute carrier family 6 (neurotransmitter transporter, GABA), member 110.032
slc2a2solute carrier family 2 (facilitated glucose transporter), member 20.032
nr2e3nuclear receptor subfamily 2, group E, member 30.031
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.031
ela2lelastase 2 like0.031
tbx1T-box 10.031
fam116bfamily with sequence similarity 116, member B0.031
btr30bloodthirsty-related gene family, member 300.030
ttpatocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency)0.030
rgs4regulator of G-protein signalling 40.030
renrenin0.030
sox21bSRY-box containing gene 21 b0.030
apoblapolipoprotein B, like0.030
gli1GLI-Kruppel family member 10.030
cryaacrystallin, alpha A0.030
inspreproinsulin0.030
fras1Fraser syndrome 10.030
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.029
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Dhc64CDynein heavy chain 64C0.717
FatpFatty acid (long chain) transport protein0.653
Fs(2)KetFemale sterile (2) Ketel0.400
CG16904CG16904 gene product from transcript CG16904-RA0.373
Ugt35aUDP-glycosyltransferase 35a0.359
CG3523CG3523 gene product from transcript CG3523-RA0.356
CG9990CG9990 gene product from transcript CG9990-RA0.344
Cyp12a4CG6042 gene product from transcript CG6042-RA0.296
Cyp12d1-pCG30489 gene product from transcript CG30489-RA0.291
Rab11Rab-protein 110.229
Arp14DActin-related protein 14D0.225
RfabgRetinoid- and fatty acid-binding glycoprotein0.213
dibdisembodied0.209
foifear-of-intimacy0.199
InRInsulin-like receptor0.189
CG3164CG3164 gene product from transcript CG3164-RA0.183
CG6660CG6660 gene product from transcript CG6660-RA0.166
CG9053CG9053 gene product from transcript CG9053-RA0.165
CG18609CG18609 gene product from transcript CG18609-RA0.165
dockdreadlocks0.154
sadshadow0.151
mofmales absent on the first0.150
CG15828CG15828 gene product from transcript CG15828-RC0.148
CG9458CG9458 gene product from transcript CG9458-RA0.146
MtpMicrosomal triacylglycerol transfer protein0.145
Yp2Yolk protein 20.144
Lsd-2Lipid storage droplet-20.135
Cyp12d1-dCG33503 gene product from transcript CG33503-RA0.134
CG1516CG1516 gene product from transcript CG1516-RP0.133
miminus0.133
Cyp9f2CG11466 gene product from transcript CG11466-RB0.133
CG15531CG15531 gene product from transcript CG15531-RB0.129
srpserpent0.129
CG7910CG7910 gene product from transcript CG7910-RA0.123
eloFelongase F0.122
CG30008CG30008 gene product from transcript CG30008-RA0.120
raspCG11495 gene product from transcript CG11495-RA0.120
Letm1CG4589 gene product from transcript CG4589-RB0.118
ttm50tiny tim 500.113
Hr96Hormone receptor-like in 960.112
Cyp6d5CG3050 gene product from transcript CG3050-RA0.111
CG4389CG4389 gene product from transcript CG4389-RA0.110
Cyp6a21CG10247 gene product from transcript CG10247-RA0.110
Cyp6g1CG8453 gene product from transcript CG8453-RA0.109
Fad2CG7923 gene product from transcript CG7923-RA0.098
CG6834CG6834 gene product from transcript CG6834-RA0.097
Cyp12a5CG11821 gene product from transcript CG11821-RA0.095
CG5508CG5508 gene product from transcript CG5508-RA0.094
Acox57D-pacyl-Coenzyme A oxidase at 57D proximal0.093
desat1CG5887 gene product from transcript CG5887-RA0.093
CG6283CG6283 gene product from transcript CG6283-RA0.092
CG17734CG17734 gene product from transcript CG17734-RA0.089
ThorCG8846 gene product from transcript CG8846-RA0.088
CG14820CG14820 gene product from transcript CG14820-RA0.088
mblmuscleblind0.088
Cyp6a23CG10242 gene product from transcript CG10242-RA0.085
Trf2TATA box binding protein-related factor 20.085
CSN4COP9 complex homolog subunit 40.084
stepsteppke0.083
Cyp4e2Cytochrome P450-4e20.081
AdhAlcohol dehydrogenase0.079
Cyp28d1CG10833 gene product from transcript CG10833-RA0.079
CG4020CG4020 gene product from transcript CG4020-RA0.078
alpha-Est7alpha-Esterase-70.077
ric8aCG15797 gene product from transcript CG15797-RA0.075
SodSuperoxide dismutase0.074
CG12672CG12672 gene product from transcript CG12672-RA0.074
CG2064CG2064 gene product from transcript CG2064-RA0.073
diadiaphanous0.073
CG9953CG9953 gene product from transcript CG9953-RA0.073
Npc1aNiemann-Pick type C-1a0.072
PhmPeptidylglycine-alpha-hydroxylating monooxygenase0.071
Cyp28a5CG8864 gene product from transcript CG8864-RA0.070
Cyp4g1Cytochrome P450-4g10.069
CG9459CG9459 gene product from transcript CG9459-RA0.067
jarjaguar0.067
CG2765CG2765 gene product from transcript CG2765-RE0.067
Atg18Autophagy-specific gene 180.066
Yp3Yolk protein 30.066
CG12428CG12428 gene product from transcript CG12428-RB0.066
CG8814CG8814 gene product from transcript CG8814-RA0.065
Cyp4ac1CG14032 gene product from transcript CG14032-RA0.063
deidelilah0.063
CG1927CG1927 gene product from transcript CG1927-RA0.062
CG5162CG5162 gene product from transcript CG5162-RA0.062
EpacCG34392 gene product from transcript CG34392-RC0.061
HphHIF prolyl hydroxylase0.061
CG5335CG5335 gene product from transcript CG5335-RA0.061
CG4558CG4558 gene product from transcript CG4558-RA0.061
PectPhosphoethanolamine cytidylyltransferase0.060
CG1443CG1443 gene product from transcript CG1443-RA0.060
CG9904CG9904 gene product from transcript CG9904-RA0.060
spasspastin0.060
HopHsp70/Hsp90 organizing protein homolog0.060
CG4753CG4753 gene product from transcript CG4753-RB0.059
Ent2Equilibrative nucleoside transporter 20.058
lazalazaro0.058
TequilaCG4821 gene product from transcript CG4821-RE0.058
CG14194CG14194 gene product from transcript CG14194-RA0.057
CG12262CG12262 gene product from transcript CG12262-RA0.057
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
DHCR77-dehydrocholesterol reductase1.000
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)1.000
FGFR2fibroblast growth factor receptor 20.999
HNF4Ahepatocyte nuclear factor 4, alpha0.999
SC4MOLsterol-C4-methyl oxidase-like0.996
FDFT1farnesyl-diphosphate farnesyltransferase 10.995
HMGCR3-hydroxy-3-methylglutaryl-CoA reductase0.995
FDPSfarnesyl diphosphate synthase0.993
FGF1fibroblast growth factor 1 (acidic)0.992
HMGCS13-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)0.979
SREBF2sterol regulatory element binding transcription factor 20.978
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.970
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.969
C14orf1chromosome 14 open reading frame 10.965
SCDstearoyl-CoA desaturase (delta-9-desaturase)0.964
SKILSKI-like oncogene0.961
SQLEsqualene epoxidase0.959
ALBalbumin0.956
CREBBPCREB binding protein0.956
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.950
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.949
VEGFAvascular endothelial growth factor A0.943
NSDHLNAD(P) dependent steroid dehydrogenase-like0.937
APOA1apolipoprotein A-I0.933
RXRAretinoid X receptor, alpha0.921
IL1R1interleukin 1 receptor, type I0.911
INSIG1insulin induced gene 10.909
GGT1gamma-glutamyltransferase 10.905
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.899
GPAA1glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)0.889
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.874
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.872
ACACAacetyl-CoA carboxylase alpha0.860
IRS1insulin receptor substrate 10.855
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.831
GH1growth hormone 10.824
DHCR2424-dehydrocholesterol reductase0.823
ARandrogen receptor0.821
FGFR1fibroblast growth factor receptor 10.812
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.795
LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)0.779
BCL3B-cell CLL/lymphoma 30.777
INSRinsulin receptor0.765
LDLRlow density lipoprotein receptor0.762
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.743
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.719
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.710
SMURF2SMAD specific E3 ubiquitin protein ligase 20.702
BRCA1breast cancer 1, early onset0.690
ALDH2aldehyde dehydrogenase 2 family (mitochondrial)0.689
SLC25A1solute carrier family 25 (mitochondrial carrier; citrate transporter), member 10.678
NOS1nitric oxide synthase 1 (neuronal)0.671
PDPK13-phosphoinositide dependent protein kinase-10.638
EBPemopamil binding protein (sterol isomerase)0.624
CSH1chorionic somatomammotropin hormone 1 (placental lactogen)0.623
HLCSholocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)0.622
MVDmevalonate (diphospho) decarboxylase0.621
ACAT2acetyl-CoA acetyltransferase 20.620
IDI1isopentenyl-diphosphate delta isomerase 10.609
ESR1estrogen receptor 10.608
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.597
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.589
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.586
NME2non-metastatic cells 2, protein (NM23B) expressed in0.582
LAMP1lysosomal-associated membrane protein 10.579
SMAD3SMAD family member 30.566
FASNfatty acid synthase0.556
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.542
PTPN6protein tyrosine phosphatase, non-receptor type 60.522
CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 10.520
HPhaptoglobin0.507
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.503
EGFRepidermal growth factor receptor0.498
CHUKconserved helix-loop-helix ubiquitous kinase0.495
BMPR1Abone morphogenetic protein receptor, type IA0.489
GH2growth hormone 20.483
GGTLC1gamma-glutamyltransferase light chain 10.477
FADS1fatty acid desaturase 10.451
ACLYATP citrate lyase0.438
SGK3serum/glucocorticoid regulated kinase family, member 30.429
APOC1apolipoprotein C-I0.425
PRKAB2protein kinase, AMP-activated, beta 2 non-catalytic subunit0.423
CTGFconnective tissue growth factor0.411
TXNthioredoxin0.402
ACAA2acetyl-CoA acyltransferase 20.396
MVKmevalonate kinase0.393
PFKLphosphofructokinase, liver0.387
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.382
SYKspleen tyrosine kinase0.382
NOXA1NADPH oxidase activator 10.379
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.376
MPDZmultiple PDZ domain protein0.375
GRB10growth factor receptor-bound protein 100.370
NR1H2nuclear receptor subfamily 1, group H, member 20.367
PTPN1protein tyrosine phosphatase, non-receptor type 10.361
ZFYVE9zinc finger, FYVE domain containing 90.357
MAP3K8mitogen-activated protein kinase kinase kinase 80.353
ABI1abl-interactor 10.353
IDH1isocitrate dehydrogenase 1 (NADP+), soluble0.352
IL1Binterleukin 1, beta0.347
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cyp51cytochrome P450, family 511.000
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 10.997
Pax8paired box gene 80.996
Idi1isopentenyl-diphosphate delta isomerase0.991
Rargretinoic acid receptor, gamma0.989
Ptenphosphatase and tensin homolog0.988
Sqlesqualene epoxidase0.987
Leprleptin receptor0.986
Arandrogen receptor0.976
Insrinsulin receptor0.974
Sc4molsterol-C4-methyl oxidase-like0.972
Ldlrlow density lipoprotein receptor0.964
Cps1carbamoyl-phosphate synthetase 10.960
Klklotho0.944
Dhcr77-dehydrocholesterol reductase0.928
Pnpla2patatin-like phospholipase domain containing 20.913
Mvdmevalonate (diphospho) decarboxylase0.908
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.888
Ghrgrowth hormone receptor0.886
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.883
Thbs1thrombospondin 10.881
Otcornithine transcarbamylase0.880
Prlrprolactin receptor0.878
Scd1stearoyl-Coenzyme A desaturase 10.878
Esr1estrogen receptor 1 (alpha)0.869
Sc5dsterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae)0.860
Dmgdhdimethylglycine dehydrogenase precursor0.852
Lsslanosterol synthase0.845
Cyp2c29cytochrome P450, family 2, subfamily c, polypeptide 290.841
AclyATP citrate lyase0.831
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.825
Fasnfatty acid synthase0.824
Bscl2Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)0.769
Cyp2b9cytochrome P450, family 2, subfamily b, polypeptide 90.765
Cyp8b1cytochrome P450, family 8, subfamily b, polypeptide 10.764
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.758
Nr1i2nuclear receptor subfamily 1, group I, member 20.753
Hsd3b3hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 30.750
Cyp2c38cytochrome P450, family 2, subfamily c, polypeptide 380.741
Acat2acetyl-Coenzyme A acetyltransferase 20.734
Apobapolipoprotein B0.729
Ppargperoxisome proliferator activated receptor gamma0.728
Cyp3a25cytochrome P450, family 3, subfamily a, polypeptide 250.711
Lef1lymphoid enhancer binding factor 10.708
Crhcorticotropin releasing hormone0.707
NsdhlNAD(P) dependent steroid dehydrogenase-like0.704
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.694
Irs2insulin receptor substrate 20.691
Trp53transformation related protein 530.686
Vdrvitamin D receptor0.685
Dram2VDNA-damage regulated autophagy modulator 20.685
Bmp4bone morphogenetic protein 40.680
Slc27a5solute carrier family 27 (fatty acid transporter), member 50.678
Pax2paired box gene 20.675
Mup19major urinary protein 190.670
Arntlaryl hydrocarbon receptor nuclear translocator-like0.658
Dhcr2424-dehydrocholesterol reductase0.652
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.648
CrpC-reactive protein, pentraxin-related0.645
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.637
F12coagulation factor XII (Hageman factor)0.631
Abcc6ATP-binding cassette, sub-family C (CFTR/MRP), member 60.629
Nfe2l2nuclear factor, erythroid derived 2, like 20.621
Ren1renin 1 structural0.613
Stard4StAR-related lipid transfer (START) domain containing 40.612
Hnf4ahepatic nuclear factor 4, alpha0.610
Sox9SRY-box containing gene 90.610
Apoa1apolipoprotein A-I0.608
Timd2T-cell immunoglobulin and mucin domain containing 20.606
Npc1Niemann Pick type C10.604
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.603
Apoeapolipoprotein E0.596
Bmp7bone morphogenetic protein 70.594
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.592
Mup10major urinary protein 100.590
Cdkn1bcyclin-dependent kinase inhibitor 1B0.586
Baatbile acid-Coenzyme A: amino acid N-acyltransferase0.584
Slc27a1solute carrier family 27 (fatty acid transporter), member 10.581
Aldobaldolase B, fructose-bisphosphate0.574
Foxa2forkhead box A20.573
Hao2hydroxyacid oxidase 20.572
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.570
Rdh11retinol dehydrogenase 110.569
Ugt2b34UDP glucuronosyltransferase 2 family, polypeptide B340.564
Grb10growth factor receptor bound protein 100.558
Cyp3a11cytochrome P450, family 3, subfamily a, polypeptide 110.552
G6pcglucose-6-phosphatase, catalytic0.551
F9coagulation factor IX0.545
Pcyt2phosphate cytidylyltransferase 2, ethanolamine0.544
Slc12a1solute carrier family 12, member 10.542
Cyp4a14cytochrome P450, family 4, subfamily a, polypeptide 140.542
Duox2dual oxidase 20.540
Aacsacetoacetyl-CoA synthetase0.540
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.537
Pik3c2gphosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide0.536
Idh1isocitrate dehydrogenase 1 (NADP+), soluble0.533
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.530
Slco1b2solute carrier organic anion transporter family, member 1b20.527
Hsd17b7hydroxysteroid (17-beta) dehydrogenase 70.522
Serpina1cserine (or cysteine) peptidase inhibitor, clade A, member 1C0.521
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ERG11Erg11p0.999
ERG25Erg25p0.995
ERG3Erg3p0.992
ERG5Erg5p0.991
ERG26Erg26p0.972
ERG28Erg28p0.938
ERG4Erg4p0.935
ERG7Erg7p0.930
INO2Ino2p0.916
ERG24Erg24p0.916
ERG27Erg27p0.891
ERG6Erg6p0.884
CHO1Cho1p0.869
ERG1Erg1p0.852
PSD1Psd1p0.845
ACC1Acc1p0.839
LAC1Lac1p0.833
LAG1Lag1p0.820
LCB1Lcb1p0.797
SCS7Scs7p0.780
GPI8Gpi8p0.767
LAS21Las21p0.686
SNF1Snf1p0.672
MDM35Mdm35p0.668
SLC1Slc1p0.657
YJU3Yju3p0.656
SIN3Sin3p0.634
GPI2Gpi2p0.621
FAS1Fas1p0.620
GSF2Gsf2p0.609
ERG8Erg8p0.595
ERG10Erg10p0.582
TOR2Tor2p0.573
PLB2Plb2p0.555
CDS1Cds1p0.533
NEM1Nem1p0.529
SAM2Sam2p0.511
PAH1Pah1p0.497
FAT1Fat1p0.457
SLG1Slg1p0.457
ROM2Rom2p0.454
SRV2Srv2p0.452
RIM101Rim101p0.450
FAB1Fab1p0.448
ERG13Erg13p0.422
IMD2Imd2p0.418
PHO86Pho86p0.411
GUP1Gup1p0.397
OPI3Opi3p0.396
LCB2Lcb2p0.387
KIN82Kin82p0.367
FAS2Fas2p0.364
EPT1Ept1p0.361
ADR1Adr1p0.358
GAA1Gaa1p0.347
GPI17Gpi17p0.345
ERG9Erg9p0.344
CTI6Cti6p0.341
MLC1Mlc1p0.329
ERG2Erg2p0.328
EHT1Eht1p0.325
DNM1Dnm1p0.321
MVD1Mvd1p0.319
PER1Per1p0.314
ORM2Orm2p0.313
POG1Pog1p0.312
CHO2Cho2p0.308
AVO1Avo1p0.306
GWT1Gwt1p0.303
SNF3Snf3p0.297
SPF1Spf1p0.291
PHO88Pho88p0.290
GAB1Gab1p0.286
MET4Met4p0.284
STT4Stt4p0.278
ERG12Erg12p0.266
OPI1Opi1p0.258
ELO1Elo1p0.257
GLO3Glo3p0.255
PCL8Pcl8p0.253
MRP8Mrp8p0.252
YNL234Whypothetical protein0.244
TVP38Tvp38p0.240
CAT8Cat8p0.240
MOB2Mob2p0.237
OLE1Ole1p0.236
GPI13Gpi13p0.232
RTS1Rts1p0.232
PTK2Ptk2p0.225
YAP7Yap7p0.224
ISC1Isc1p0.222
HAA1Haa1p0.221
SEF1Sef1p0.219
PDR17Pdr17p0.215
MIG2Mig2p0.212
ARV1Arv1p0.212
MIG3Mig3p0.211
HMG1Hmg1p0.211
IRE1Ire1p0.210
UPS1Ups1p0.210