The network for 'cellular macromolecule catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular macromolecule catabolic process

The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells.

NameDescriptionProbabilityFunc Analog Organism
Psmb3proteasome (prosome, macropain) subunit, beta type 30.638
Psma7proteasome (prosome, macropain) subunit, alpha type 70.629
Psma3proteasome (prosome, macropain) subunit, alpha type 30.497
Psma5proteasome (prosome, macropain) subunit, alpha type 50.444
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.337
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.297
Psmb6proteasome (prosome, macropain) subunit, beta type 60.292
Psme2proteasome (prosome, macropain) activator subunit 20.285
Ptges3prostaglandin E synthase 3 (cytosolic)0.273
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.243
Hspd1heat shock protein 1 (chaperonin)0.217
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.214
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.191
Nsfl1cNSFL1 (p97) cofactor (p47)0.167
Psma4proteasome (prosome, macropain) subunit, alpha type 40.157
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.157
Manfmesencephalic astrocyte-derived neurotrophic factor0.148
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.136
Stip1stress-induced phosphoprotein 10.135
Creld2cysteine-rich with EGF-like domains 20.134
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.128
Nr1d2nuclear receptor subfamily 1, group D, member 20.116
Egr1early growth response 10.112
Psmd7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.111
Oaz1ornithine decarboxylase antizyme 10.104
Eef2eukaryotic translation elongation factor 20.100
Psmb7proteasome (prosome, macropain) subunit, beta type 70.098
Hspa5heat shock protein 50.098
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.095
Hsph1heat shock 105/110 protein 10.094
Psmb2proteasome (prosome, macropain) subunit, beta type 20.084
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.082
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.081
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.077
CnbpCCHC-type zinc finger, nucleic acid binding protein0.076
Psma1proteasome (prosome, macropain) subunit, alpha type 10.073
Dnajb11DnaJ (Hsp40) homolog, subfamily B, member 110.071
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.070
Psmb4proteasome (prosome, macropain) subunit, beta type 40.069
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.068
Pdia4protein disulfide isomerase family A, member 40.068
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.064
Btg1B-cell translocation gene 1, anti-proliferative0.062
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.059
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.059
Hist1h1ahistone cluster 1, H1a0.057
Psma2proteasome (prosome, macropain) subunit, alpha type 20.054
Junbjun B proto-oncogene0.052
Csnk1dcasein kinase 1, delta0.052
Spcs2signal peptidase complex subunit 2 homolog (S. cerevisiae)0.051
FosFBJ osteosarcoma oncogene0.051
Ccnb1cyclin B10.050
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.050
Tolliptoll interacting protein0.048
Plk1polo-like kinase 1 (Drosophila)0.048
Vcpvalosin-containing protein0.047
Txnl1thioredoxin-like 10.045
Psmd5proteasome (prosome, macropain) 26S subunit, non-ATPase, 50.044
Mapre1microtubule-associated protein, RP/EB family, member 10.042
Dusp11dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)0.042
Taok1TAO kinase 10.041
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.041
Psmd14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.040
Rpn1ribophorin I0.040
Hk1hexokinase 10.039
Cand1cullin-associated and neddylation-dissociated 10.038
Caprin1cell cycle associated protein 10.037
Shank2SH3 and multiple ankyrin repeat domains 20.037
Usp19ubiquitin specific peptidase 190.037
Dnajc5DnaJ (Hsp40) homolog, subfamily C, member 50.036
Gja1gap junction protein, alpha 10.035
Cct3chaperonin containing Tcp1, subunit 3 (gamma)0.034
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.033
Papolapoly (A) polymerase alpha0.033
Pdia6protein disulfide isomerase family A, member 60.033
Dlg3discs, large homolog 3 (Drosophila)0.033
Psmb5proteasome (prosome, macropain) subunit, beta type 50.033
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.032
Cyr61cysteine-rich, angiogenic inducer, 610.031
Akt1s1AKT1 substrate 1 (proline-rich)0.031
Eif4heukaryotic translation initiation factor 4H0.030
Rab21RAB21, member RAS oncogene family0.030
Zfand5zinc finger, AN1-type domain 50.030
Snd1staphylococcal nuclease and tudor domain containing 10.030
Rasgrp1RAS guanyl releasing protein 1 (calcium and DAG-regulated)0.029
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.029
Alkbh5alkB, alkylation repair homolog 5 (E. coli)0.029
Acyp2acylphosphatase 2, muscle type0.029
Lin7clin-7 homolog C (C. elegans)0.028
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.028
Psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.028
Phaxphosphorylated adaptor for RNA export0.028
Usp47ubiquitin specific peptidase 470.027
Troaptrophinin associated protein0.027
Ier2immediate early response 20.027
Rab5aRAB5A, member RAS oncogene family0.027
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.027
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
rpn-12Protein RPN-120.212
rpn-7Protein RPN-70.194
pas-4Protein PAS-40.177
rpt-2Protein RPT-20.151
taf-5Protein TAF-50.127
pbs-6Protein PBS-60.114
atx-3Protein ATX-30.111
tba-2Protein TBA-20.104
imb-2Protein IMB-20.101
stam-1Protein STAM-10.100
rpn-6.1Protein RPN-6.10.097
rad-51Protein RAD-510.093
snr-2Protein SNR-20.085
rpt-3Protein RPT-30.082
CELE_K08F4.1Protein K08F4.10.079
larp-5Protein LARP-50.073
rpt-5Protein RPT-50.072
pbs-1Protein PBS-10.071
cul-1Protein CUL-10.070
cdl-1Protein CDL-10.069
pbs-5Protein PBS-50.068
mig-5Protein MIG-50.067
pas-6Protein PAS-60.065
dpy-30Protein DPY-300.062
hgrs-1Protein HGRS-10.061
thoc-2Protein THOC-20.061
pas-2Protein PAS-20.057
npl-4.2Protein NPL-4.20.057
rnr-1Protein RNR-10.057
cdc-48.2Protein CDC-48.20.054
T06D8.7Protein T06D8.70.054
R05H5.3Protein R05H5.30.053
pgl-1Protein PGL-10.052
ire-1Protein IRE-10.052
K08E3.5Protein K08E3.50.052
him-10Protein HIM-100.052
pbs-7Protein PBS-70.052
rpn-3Protein RPN-30.051
F46F11.6Protein F46F11.60.051
ztf-7Protein ZTF-70.051
npp-22Protein NPP-220.051
ZC395.10Protein ZC395.100.050
pas-1Protein PAS-10.049
let-99Protein LET-990.048
F56D2.6Protein F56D2.60.046
rpt-1Protein RPT-10.046
rpl-11.1Protein RPL-11.10.045
smc-3Protein SMC-30.045
vps-28Protein VPS-280.044
mel-26Protein MEL-260.044
ubxn-4Protein UBXN-40.043
rsp-8Protein RSP-80.043
pkc-3Protein PKC-30.043
C42C1.4Protein C42C1.40.043
ntl-2Protein NTL-20.042
pcn-1Protein PCN-10.042
adr-2Protein ADR-20.042
akt-1Protein AKT-10.041
Y47D3A.29Protein Y47D3A.290.041
rpn-11Protein RPN-110.041
R11A8.7Protein R11A8.70.041
spas-1Protein SPAS-10.041
pbs-3Protein PBS-30.041
spn-4Protein SPN-40.040
lin-23Protein LIN-230.040
zen-4Protein ZEN-40.040
CELE_Y57A10A.13Protein Y57A10A.130.038
nap-1Protein NAP-10.038
T05E8.3Protein T05E8.30.038
knl-3Protein KNL-30.038
rfc-2Protein RFC-20.038
pap-1Protein PAP-10.038
nhr-86Protein NHR-860.038
htz-1Protein HTZ-10.038
rps-2Protein RPS-20.037
CELE_W02D7.6Protein W02D7.60.036
F08B4.7Protein F08B4.70.036
F25B3.6Protein F25B3.60.036
hsr-9Protein HSR-90.035
taf-9Protein TAF-90.035
CELE_R102.5Protein R102.50.035
klp-16Protein KLP-160.035
gck-2Protein GCK-20.035
sur-6Protein SUR-60.035
pbs-4Protein PBS-40.035
R12C12.6Protein R12C12.60.035
lst-3Protein LST-30.035
mrck-1Protein MRCK-10.035
E01A2.6Protein E01A2.60.035
D1007.8Protein D1007.80.035
rpn-5Protein RPN-50.035
F31D4.2Protein F31D4.20.034
crt-1Protein CRT-10.034
zyg-9Protein ZYG-90.034
T27A3.2Protein T27A3.20.034
asd-1Protein ASD-10.034
T01D3.5Protein T01D3.50.034
H14E04.2Protein H14E04.20.034
rod-1Protein ROD-10.034
dnj-12Protein DNJ-120.034
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
psmb1proteasome (prosome, macropain) subunit, beta type, 10.583
psma6aproteasome (prosome, macropain) subunit, alpha type, 6a0.498
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.477
psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.390
smad5MAD homolog 5 (Drosophila)0.361
pcnaproliferating cell nuclear antigen0.317
psma8proteasome (prosome, macropain) subunit, alpha type, 80.201
psma1proteasome (prosome, macropain) subunit, alpha type, 10.188
psmb3proteasome (prosome, macropain) subunit, beta type, 30.141
psmd4bproteasome (prosome, macropain) 26S subunit, non-ATPase, 4b0.133
psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.131
psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.130
rab1aRAB1A, member RAS oncogene family0.120
ef1aelongation factor 1-alpha0.108
psmb5proteasome (prosome, macropain) subunit, beta type, 50.104
ccnb1cyclin B10.096
rnaset2ribonuclease T20.095
syvn1synovial apoptosis inhibitor 1, synoviolin0.085
chukconserved helix-loop-helix ubiquitous kinase0.082
naspnuclear autoantigenic sperm protein (histone-binding)0.081
psmb7proteasome (prosome, macropain) subunit, beta type, 70.080
supt6hsuppressor of Ty 6 homolog0.078
hspa5heat shock protein 50.071
maxmyc-associated factor X0.067
bsdc1BSD domain containing 10.060
wdhd1WD repeat and HMG-box DNA binding protein 10.060
vcpvalosin containing protein0.059
ccna2cyclin A20.059
mcts1malignant T cell amplified sequence 10.058
tp53tumor protein p530.056
tram1translocating chain-associating membrane protein 10.056
psmb4proteasome (prosome, macropain) subunit, beta type, 40.056
sap18sin3-associated polypeptide0.054
psmc3proteasome (prosome, macropain) 26S subunit, ATPase, 30.053
sumo3aSMT3 suppressor of mif two 3 homolog 3a0.052
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.052
h2afvH2A histone family, member V0.050
puf60bpoly-U binding splicing factor b0.048
acvr1bactivin A receptor, type IB0.044
ube2g2ubiquitin-conjugating enzyme E2G 20.044
psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.043
faf2Fas associated factor family member 20.042
foxo3bforkhead box O3b0.041
psmb2proteasome (prosome, macropain) subunit, beta type, 20.041
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.040
smg5Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)0.040
ncapd2non-SMC condensin I complex, subunit D20.040
psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.039
cnn2calponin 20.039
smg1PI-3-kinase-related kinase SMG-10.038
ctsccathepsin C0.037
aurkbaurora kinase B0.037
usp5ubiquitin specific protease 50.036
gps1G protein pathway suppressor 10.036
gro2groucho 20.036
bonbonnie and clyde0.036
tmem93transmembrane protein 930.035
psma5proteasome (prosome, macropain) subunit, alpha type,50.035
psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.035
ube2naubiquitin-conjugating enzyme E2Na0.034
terfatelomeric repeat binding factor a0.034
rbm4.2RNA binding motif protein 4.20.034
e2f5E2F transcription factor 50.033
snai1asnail homolog 1a (Drosophila)0.033
tia1lcytotoxic granule-associated RNA binding protein 1, like0.033
smc4structural maintenance of chromosomes 40.033
kif23kinesin family member 230.033
LOC100330405transmembrane protein 176B-like0.032
psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.032
eif2c4eukaryotic translation initiation factor 2C, 40.032
fanclFanconi anemia, complementation group L0.031
ilf2interleukin enhancer binding factor 20.031
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.031
brca2breast cancer 2, early onset0.030
upf2UPF2 regulator of nonsense transcripts homolog (yeast)0.028
ubinataxin-1 ubiquitin-like interacting protein0.028
crklv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.028
upf1upf1 regulator of nonsense transcripts homolog (yeast)0.028
ddx42DEAD (Asp-Glu-Ala-Asp) box polypeptide 420.027
ck2bcasein kinase 2 beta0.027
adrm1badhesion regulating molecule 1b0.027
ciapin1cytokine induced apoptosis inhibitor 10.027
akirin2akirin 20.026
smarce1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.026
btg2B-cell translocation gene 20.026
elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.026
eif1beukaryotic translation initiation factor 1B0.025
rlfrearranged L-myc fusion0.025
dnmt1DNA (cytosine-5-)-methyltransferase 10.025
psmc1bproteasome (prosome, macropain) 26S subunit, ATPase, 1b0.025
smg6Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)0.025
ube2d2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)0.024
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
tefutelomere fusion0.932
Rpt1CG1341 gene product from transcript CG1341-RA0.881
Prosbeta2Proteasome beta2 subunit0.723
Fcp1CG12252 gene product from transcript CG12252-RA0.648
Rpn11CG18174 gene product from transcript CG18174-RA0.640
p53CG33336 gene product from transcript CG33336-RB0.608
CycBCyclin B0.581
Uba1Ubiquitin activating enzyme 10.578
Mov34CG3416 gene product from transcript CG3416-RA0.566
cdc2CG5363 gene product from transcript CG5363-RA0.547
traltrailer hitch0.490
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.480
Rpt3CG16916 gene product from transcript CG16916-RA0.480
Rpn9CG10230 gene product from transcript CG10230-RB0.476
Rpn6Proteasome p44.5 subunit0.472
Rpt4CG3455 gene product from transcript CG3455-RA0.463
CG11347CG11347 gene product from transcript CG11347-RE0.445
CG13349CG13349 gene product from transcript CG13349-RA0.439
CycDCyclin D0.425
CycGCyclin G0.419
CkIIbetaCasein kinase II beta subunit0.416
Pros35Proteasome 35kD subunit0.407
Hel25EHelicase at 25E0.405
B52CG10851 gene product from transcript CG10851-RB0.405
skpACG16983 gene product from transcript CG16983-RD0.401
UbcD2Ubiquitin conjugating enzyme 20.394
poepurity of essence0.393
Top1Topoisomerase 10.392
CkIIalphaCasein kinase II alpha subunit0.385
mspsmini spindles0.381
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.373
Tbp-1Tat-binding protein-10.369
Bj1Bj1 protein0.368
smt3CG4494 gene product from transcript CG4494-RA0.364
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.355
CG12321CG12321 gene product from transcript CG12321-RA0.348
Cap-GCG34438 gene product from transcript CG34438-RF0.338
CkIalphaCasein kinase Ialpha0.327
Prosbeta3Proteasome beta3 subunit0.319
Tip60CG6121 gene product from transcript CG6121-RA0.308
sec5CG8843 gene product from transcript CG8843-RA0.306
spn-Espindle E0.305
DNApol-alpha180DNA polymerase alpha 180kD0.304
hydhyperplastic discs0.299
CG17331CG17331 gene product from transcript CG17331-RA0.296
MED15Mediator complex subunit 150.295
RhoGEF2CG9635 gene product from transcript CG9635-RF0.290
lqfliquid facets0.287
Hsc70-4Heat shock protein cognate 40.287
bratbrain tumor0.285
His2AvHistone H2A variant0.282
mib1mind bomb 10.279
CG6854CG6854 gene product from transcript CG6854-RC0.277
Pros26Proteasome 26kD subunit0.275
mei-9meiotic 90.272
IncenpInner centromere protein0.270
Prosbeta1Proteasome beta1 subunit0.269
CG8979CG8979 gene product from transcript CG8979-RC0.269
Rpn2CG11888 gene product from transcript CG11888-RA0.262
hipkhomeodomain interacting protein kinase0.261
Pros29Proteasome 29kD subunit0.258
CG7878CG7878 gene product from transcript CG7878-RA0.257
Rox8CG5422 gene product from transcript CG5422-RD0.253
EcREcdysone receptor0.251
SaraSmad anchor for receptor activation0.249
Rpn12CG4157 gene product from transcript CG4157-RA0.249
RpS20Ribosomal protein S200.243
PsaPuromycin sensitive aminopeptidase0.241
Rpn1CG7762 gene product from transcript CG7762-RA0.238
CG34415CG34415 gene product from transcript CG34415-RC0.233
swmsecond mitotic wave missing0.230
Prosbeta7Proteasome beta7 subunit0.227
Trf2TATA box binding protein-related factor 20.226
CG9576CG9576 gene product from transcript CG9576-RA0.215
Aos1CG12276 gene product from transcript CG12276-RA0.213
BRWD3CG31132 gene product from transcript CG31132-RA0.212
TfIIFbetaTranscription factor TFIIFbeta0.207
CG11885CG11885 gene product from transcript CG11885-RA0.206
spn-Bspindle B0.201
RYBPRing and YY1 Binding Protein0.198
Rcd1Reduction in Cnn dots 10.197
slmbsupernumerary limbs0.193
CG11486CG11486 gene product from transcript CG11486-RG0.189
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
UBCubiquitin C1.000
TP53tumor protein p531.000
RNF11ring finger protein 111.000
UPF1UPF1 regulator of nonsense transcripts homolog (yeast)1.000
XIAPX-linked inhibitor of apoptosis1.000
UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)1.000
SKP1S-phase kinase-associated protein 11.000
VCPvalosin containing protein1.000
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide1.000
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)1.000
PSMA3proteasome (prosome, macropain) subunit, alpha type, 31.000
BRCA1breast cancer 1, early onset0.999
PABPC1poly(A) binding protein, cytoplasmic 10.999
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.999
MDM2Mdm2 p53 binding protein homolog (mouse)0.999
PSMA2proteasome (prosome, macropain) subunit, alpha type, 20.999
SKP2S-phase kinase-associated protein 2 (p45)0.998
UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)0.998
CUL1cullin 10.998
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.998
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.998
CUL3cullin 30.997
EXOSC3exosome component 30.997
RBX1ring-box 1, E3 ubiquitin protein ligase0.997
PSMA6proteasome (prosome, macropain) subunit, alpha type, 60.996
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.995
CASP3caspase 3, apoptosis-related cysteine peptidase0.994
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.994
SYVN1synovial apoptosis inhibitor 1, synoviolin0.992
HSPA8heat shock 70kDa protein 80.991
SMG1SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)0.991
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.991
RBM8ARNA binding motif protein 8A0.991
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.989
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.988
UBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)0.988
BIRC2baculoviral IAP repeat containing 20.987
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.985
PSMA1proteasome (prosome, macropain) subunit, alpha type, 10.985
PSMA5proteasome (prosome, macropain) subunit, alpha type, 50.981
CCNA2cyclin A20.978
PTK2PTK2 protein tyrosine kinase 20.974
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.974
TCEB1transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)0.973
CDC20cell division cycle 20 homolog (S. cerevisiae)0.973
UPF3AUPF3 regulator of nonsense transcripts homolog A (yeast)0.972
CHEK1CHK1 checkpoint homolog (S. pombe)0.972
FBXW11F-box and WD repeat domain containing 110.970
EXOSC4exosome component 40.965
CUL2cullin 20.965
TNRC6Atrinucleotide repeat containing 6A0.963
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.963
EXOSC10exosome component 100.963
PSMB6proteasome (prosome, macropain) subunit, beta type, 60.961
ARIH2ariadne homolog 2 (Drosophila)0.958
CASP8caspase 8, apoptosis-related cysteine peptidase0.955
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.953
ANAPC4anaphase promoting complex subunit 40.952
SNX9sorting nexin 90.950
BIRC3baculoviral IAP repeat containing 30.950
UBE3Aubiquitin protein ligase E3A0.947
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.945
BTRCbeta-transducin repeat containing0.941
CDC27cell division cycle 27 homolog (S. cerevisiae)0.941
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.939
NEDD8neural precursor cell expressed, developmentally down-regulated 80.939
QKIquaking homolog, KH domain RNA binding (mouse)0.939
CCNB1cyclin B10.938
RB1retinoblastoma 10.933
VHLvon Hippel-Lindau tumor suppressor0.932
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.932
DIS3LDIS3 mitotic control homolog (S. cerevisiae)-like0.924
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.924
RAD23BRAD23 homolog B (S. cerevisiae)0.923
HUWE1HECT, UBA and WWE domain containing 10.923
SMAD4SMAD family member 40.920
OTUB1OTU domain, ubiquitin aldehyde binding 10.920
UPF2UPF2 regulator of nonsense transcripts homolog (yeast)0.918
CASP9caspase 9, apoptosis-related cysteine peptidase0.917
PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.917
PSMB2proteasome (prosome, macropain) subunit, beta type, 20.914
SMURF2SMAD specific E3 ubiquitin protein ligase 20.913
POMPproteasome maturation protein0.911
DERL1Der1-like domain family, member 10.909
TNRC6Ctrinucleotide repeat containing 6C0.898
TSG101tumor susceptibility gene 1010.897
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)0.896
PDCD6IPprogrammed cell death 6 interacting protein0.894
TRIM39tripartite motif containing 390.894
TRAF6TNF receptor-associated factor 60.890
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.887
PSMB1proteasome (prosome, macropain) subunit, beta type, 10.885
RNF111ring finger protein 1110.883
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.882
CDC16cell division cycle 16 homolog (S. cerevisiae)0.879
UPF3BUPF3 regulator of nonsense transcripts homolog B (yeast)0.874
RNF5ring finger protein 50.873
CDT1chromatin licensing and DNA replication factor 10.872
UBQLN1ubiquilin 10.871
FAF2Fas associated factor family member 20.870
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.999
Ctnnb1catenin (cadherin associated protein), beta 10.999
Per2period homolog 2 (Drosophila)0.987
Ptenphosphatase and tensin homolog0.980
Axin1axin 10.971
Psma1proteasome (prosome, macropain) subunit, alpha type 10.967
Gsk3bglycogen synthase kinase 3 beta0.966
Per1period homolog 1 (Drosophila)0.965
Psma2proteasome (prosome, macropain) subunit, alpha type 20.941
Cry2cryptochrome 2 (photolyase-like)0.925
Vhlvon Hippel-Lindau tumor suppressor0.913
Psmb6proteasome (prosome, macropain) subunit, beta type 60.911
Psma5proteasome (prosome, macropain) subunit, alpha type 50.905
Clockcircadian locomotor output cycles kaput0.903
Psma3proteasome (prosome, macropain) subunit, alpha type 30.903
Nedd4neural precursor cell expressed, developmentally down-regulated 40.901
Thrathyroid hormone receptor alpha0.900
Psmb7proteasome (prosome, macropain) subunit, beta type 70.889
Psmb4proteasome (prosome, macropain) subunit, beta type 40.882
Ccnb1cyclin B10.878
Fgfr1fibroblast growth factor receptor 10.875
Apcadenomatosis polyposis coli0.867
Arntlaryl hydrocarbon receptor nuclear translocator-like0.863
Hspa5heat shock protein 50.862
Smad3MAD homolog 3 (Drosophila)0.861
Psma7proteasome (prosome, macropain) subunit, alpha type 70.860
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.856
Pias1protein inhibitor of activated STAT 10.846
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.831
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.810
Ncoa3nuclear receptor coactivator 30.788
Traf6TNF receptor-associated factor 60.786
Psmd14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.785
Adrm1adhesion regulating molecule 10.782
Cdk1cyclin-dependent kinase 10.781
Brca1breast cancer 10.778
Bcl2B-cell leukemia/lymphoma 20.777
Rc3h1RING CCCH (C3H) domains 10.769
Cyldcylindromatosis (turban tumor syndrome)0.759
Psma6proteasome (prosome, macropain) subunit, alpha type 60.752
Psmc5protease (prosome, macropain) 26S subunit, ATPase 50.730
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.726
Usp9xubiquitin specific peptidase 9, X chromosome0.718
Dvl1dishevelled, dsh homolog 1 (Drosophila)0.713
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.703
Cul3cullin 30.702
Ccndbp1cyclin D-type binding-protein 10.672
Psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.664
Brca2breast cancer 20.664
Pax8paired box gene 80.653
C330027C09RikRIKEN cDNA C330027C09 gene0.652
Cdk4cyclin-dependent kinase 40.640
Smad4MAD homolog 4 (Drosophila)0.633
Mcl1myeloid cell leukemia sequence 10.630
Vcpvalosin containing protein0.630
Ncapg2non-SMC condensin II complex, subunit G20.622
Smad7MAD homolog 7 (Drosophila)0.618
Ube2nubiquitin-conjugating enzyme E2N0.618
Plin1perilipin 10.611
Insrinsulin receptor0.610
Ect2ect2 oncogene0.607
Cdkn1bcyclin-dependent kinase inhibitor 1B0.606
Hdac6histone deacetylase 60.604
Egr2early growth response 20.599
Lrp6low density lipoprotein receptor-related protein 60.598
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.598
Rbl2retinoblastoma-like 20.590
Ccne1cyclin E10.586
Mdm2transformed mouse 3T3 cell double minute 20.576
Manfmesencephalic astrocyte-derived neurotrophic factor0.566
Map3k7mitogen-activated protein kinase kinase kinase 70.562
Hellshelicase, lymphoid specific0.555
Eif2c2eukaryotic translation initiation factor 2C, 20.552
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.548
Ptch1patched homolog 10.548
Dnajb11DnaJ (Hsp40) homolog, subfamily B, member 110.546
Chek1checkpoint kinase 1 homolog (S. pombe)0.544
Skp1aS-phase kinase-associated protein 1A0.537
Ranbp9RAN binding protein 90.534
Tbcbtubulin folding cofactor B0.533
RanRAN, member RAS oncogene family0.529
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)0.529
Ulk2Unc-51 like kinase 2 (C. elegans)0.520
Rb1retinoblastoma 10.516
Psme2proteasome (prosome, macropain) 28 subunit, beta0.510
Creld2cysteine-rich with EGF-like domains 20.509
Pkn2protein kinase N20.503
Csnk1ecasein kinase 1, epsilon0.490
Stat3signal transducer and activator of transcription 30.487
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.484
Setdb1SET domain, bifurcated 10.474
Apoeapolipoprotein E0.467
Pompproteasome maturation protein0.465
G2e3G2/M-phase specific E3 ubiquitin ligase0.463
Dyrk1adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a0.460
Wdr26WD repeat domain 260.458
2610039C10RikRIKEN cDNA 2610039C10 gene0.455
Wdhd1WD repeat and HMG-box DNA binding protein 10.453
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
YJL163Chypothetical protein0.528