The network for 'positive regulation of receptor activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of receptor activity

Any process that activates or increases the frequency, rate or extent of receptor activity.

NameDescriptionProbabilityFunc Analog Organism
Rgs9regulator of G-protein signaling 90.024
Cngb1cyclic nucleotide gated channel beta 10.024
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.020
Prkaa2protein kinase, AMP-activated, alpha 2 catalytic subunit0.020
Apba2amyloid beta (A4) precursor protein-binding, family A, member 20.019
Slc6a9solute carrier family 6 (neurotransmitter transporter, glycine), member 90.019
Tcf4transcription factor 40.018
Pip5k1cphosphatidylinositol-4-phosphate 5-kinase, type I, gamma0.018
Taf6TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor0.018
Gna11guanine nucleotide binding protein, alpha 110.018
Tacr1tachykinin receptor 10.018
Slco2b1solute carrier organic anion transporter family, member 2b10.018
Cplx2complexin 20.017
Rai1retinoic acid induced 10.016
Grip1glutamate receptor interacting protein 10.016
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.016
BspryB-box and SPRY domain containing0.016
RorbRAR-related orphan receptor B0.016
Pde2aphosphodiesterase 2A, cGMP-stimulated0.016
Pparaperoxisome proliferator activated receptor alpha0.015
Dlgap3discs, large (Drosophila) homolog-associated protein 30.015
Trraptransformation/transcription domain-associated protein0.015
Insrrinsulin receptor-related receptor0.015
Fgfr4fibroblast growth factor receptor 40.015
Deaf1deformed epidermal autoregulatory factor 1 (Drosophila)0.015
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.015
Pgam2phosphoglycerate mutase 2 (muscle)0.014
Epn2epsin 20.014
Notch4Notch homolog 4 (Drosophila)0.014
Slco2a1solute carrier organic anion transporter family, member 2a10.013
Lphn1latrophilin 10.013
Myo10myosin X0.013
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.013
Nrp1neuropilin 10.013
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.013
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.013
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.013
Igsf1immunoglobulin superfamily, member 10.013
Drd2dopamine receptor D20.013
Pygmphosphorylase, glycogen, muscle0.013
Adra1badrenergic, alpha-1B-, receptor0.012
Usf2upstream transcription factor 2, c-fos interacting0.012
Sox2SRY (sex determining region Y)-box 20.012
Lsamplimbic system-associated membrane protein0.012
Prkar2aprotein kinase, cAMP dependent regulatory, type II alpha0.012
Clcn4-2chloride channel 4-20.012
KhsrpKH-type splicing regulatory protein0.012
Atp7bATPase, Cu++ transporting, beta polypeptide0.012
Thrathyroid hormone receptor alpha0.012
Crygacrystallin, gamma A0.012
Acox3acyl-Coenzyme A oxidase 3, pristanoyl0.012
Mthfrmethylenetetrahydrofolate reductase (NAD(P)H)0.012
Extl3exostoses (multiple)-like 30.011
Syt7synaptotagmin VII0.011
Tnrc6btrinucleotide repeat containing 6B0.011
Uhmk1U2AF homology motif (UHM) kinase 10.011
Gpr27G protein-coupled receptor 270.011
Tnrtenascin R0.011
Ldlrlow density lipoprotein receptor0.011
Galr3galanin receptor 30.011
Necab2N-terminal EF-hand calcium binding protein 20.011
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.011
Prdm2PR domain containing 2, with ZNF domain0.011
Ngfnerve growth factor (beta polypeptide)0.011
Lypd3Ly6/Plaur domain containing 30.011
Axin2axin 20.011
Myoz2myozenin 20.011
Itgamintegrin, alpha M0.011
Slc13a3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 30.011
Nr2c2nuclear receptor subfamily 2, group C, member 20.011
Hpcal4hippocalcin-like 40.011
Arandrogen receptor0.011
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.011
Cntfrciliary neurotrophic factor receptor0.011
Syt6synaptotagmin VI0.011
Gdf11growth differentiation factor 110.011
CamkvCaM kinase-like vesicle-associated0.011
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.011
Slc36a1solute carrier family 36 (proton/amino acid symporter), member 10.011
B4galt2UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 20.011
Abcc8ATP-binding cassette, subfamily C (CFTR/MRP), member 80.011
Tpcn1two pore segment channel 10.011
Sptbn2spectrin, beta, non-erythrocytic 20.011
Olr337olfactory receptor 3370.011
Elf3E74-like factor 30.011
Nfibnuclear factor I/B0.011
Srebf1sterol regulatory element binding transcription factor 10.010
Il1ainterleukin 1 alpha0.010
Accn2amiloride-sensitive cation channel 2, neuronal0.010
Kalrnkalirin, RhoGEF kinase0.010
Cd44Cd44 molecule0.010
Slc4a4solute carrier family 4, sodium bicarbonate cotransporter, member 40.010
Ptprz1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.010
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.010
Pcnxl3pecanex-like 3 (Drosophila)0.010
Camk2gcalcium/calmodulin-dependent protein kinase II gamma0.010
Metmet proto-oncogene0.010
Dpy19l1dpy-19-like 1 (C. elegans)0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ldb3LIM domain binding 30.864
Msx1homeobox, msh-like 10.199
Gdf5growth differentiation factor 50.165
Il6stinterleukin 6 signal transducer0.134
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.127
Emx1empty spiracles homolog 1 (Drosophila)0.123
Tgfatransforming growth factor alpha0.122
Dlg4discs, large homolog 4 (Drosophila)0.116
Prkceprotein kinase C, epsilon0.112
Smad3MAD homolog 3 (Drosophila)0.094
Carm1coactivator-associated arginine methyltransferase 10.087
Gpc3glypican 30.084
SrcRous sarcoma oncogene0.080
Bmp4bone morphogenetic protein 40.076
Fgfr1fibroblast growth factor receptor 10.074
Esr1estrogen receptor 1 (alpha)0.070
Lrp1low density lipoprotein receptor-related protein 10.063
Apcadenomatosis polyposis coli0.060
Ncoa6nuclear receptor coactivator 60.059
Pitx2paired-like homeodomain transcription factor 20.059
Foxc1forkhead box C10.058
Pkd1polycystic kidney disease 1 homolog0.056
Fgfr2fibroblast growth factor receptor 20.055
Clockcircadian locomotor output cycles kaput0.055
Thrathyroid hormone receptor alpha0.051
Hand1heart and neural crest derivatives expressed transcript 10.049
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.049
Cpeb3cytoplasmic polyadenylation element binding protein 30.048
Dlgap1discs, large (Drosophila) homolog-associated protein 10.045
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.043
Tjp1tight junction protein 10.038
Epas1endothelial PAS domain protein 10.038
Slc16a2solute carrier family 16 (monocarboxylic acid transporters), member 20.037
Wnt7bwingless-related MMTV integration site 7B0.036
Nr3c1nuclear receptor subfamily 3, group C, member 10.036
Bicc1bicaudal C homolog 1 (Drosophila)0.034
Egfrepidermal growth factor receptor0.033
Fgfr3fibroblast growth factor receptor 30.033
Gdf10growth differentiation factor 100.033
Gdf3growth differentiation factor 30.033
Hbb-b1hemoglobin, beta adult major chain0.032
Cdkn1ccyclin-dependent kinase inhibitor 1C (P57)0.031
Skiski sarcoma viral oncogene homolog (avian)0.030
Setdb1SET domain, bifurcated 10.030
Tgfb2transforming growth factor, beta 20.029
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.029
Zic3zinc finger protein of the cerebellum 30.029
Nos1nitric oxide synthase 1, neuronal0.028
Sfrp2secreted frizzled-related protein 20.028
AxlAXL receptor tyrosine kinase0.027
Dnm1dynamin 10.027
Col14a1collagen, type XIV, alpha 10.026
Otx2orthodenticle homolog 2 (Drosophila)0.026
Dab1disabled homolog 1 (Drosophila)0.025
Ahi1Abelson helper integration site 10.024
Sall4sal-like 4 (Drosophila)0.023
Adcy9adenylate cyclase 90.023
RestRE1-silencing transcription factor0.023
Gli3GLI-Kruppel family member GLI30.022
Dkk1dickkopf homolog 1 (Xenopus laevis)0.022
Slc25a25solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 250.022
Gdf1growth differentiation factor 10.022
Eomeseomesodermin homolog (Xenopus laevis)0.022
Bmpr1abone morphogenetic protein receptor, type 1A0.022
Gdf6growth differentiation factor 60.022
Nos3nitric oxide synthase 3, endothelial cell0.021
Bmp7bone morphogenetic protein 70.021
Prkccprotein kinase C, gamma0.021
Gas1growth arrest specific 10.021
Ncoa1nuclear receptor coactivator 10.021
Igf1rinsulin-like growth factor I receptor0.020
Nr6a1nuclear receptor subfamily 6, group A, member 10.020
Cxcl12chemokine (C-X-C motif) ligand 120.020
Tbx15T-box 150.019
Gsdma3gasdermin A30.019
Ptenphosphatase and tensin homolog0.019
Ufc1ubiquitin-fold modifier conjugating enzyme 10.019
Klf3Kruppel-like factor 3 (basic)0.018
Ror2receptor tyrosine kinase-like orphan receptor 20.018
Islrimmunoglobulin superfamily containing leucine-rich repeat0.018
RoraRAR-related orphan receptor alpha0.018
Mapk14mitogen-activated protein kinase 140.018
Lefty1left right determination factor 10.018
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.018
Aebp1AE binding protein 10.018
Grb10growth factor receptor bound protein 100.017
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.017
Igf2rinsulin-like growth factor 2 receptor0.017
Gli2GLI-Kruppel family member GLI20.017
Nr2e1nuclear receptor subfamily 2, group E, member 10.017
Camk2bcalcium/calmodulin-dependent protein kinase II, beta0.017
Rassf5Ras association (RalGDS/AF-6) domain family member 50.016
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.016
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.015
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.015
Meox2mesenchyme homeobox 20.015
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism