The network for 'regulation of defense response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of defense response

Any process that modulates the frequency, rate or extent of a defense response.

NameDescriptionProbabilityFunc Analog Organism
Il1binterleukin 1 beta0.351
Tlr4toll-like receptor 40.327
S100a9S100 calcium binding protein A90.312
Cd38CD38 molecule0.308
Tnftumor necrosis factor (TNF superfamily, member 2)0.252
Ednraendothelin receptor type A0.228
Iappislet amyloid polypeptide0.226
Pzppregnancy-zone protein0.225
Il8rbinterleukin 8 receptor, beta0.211
Hes2hairy and enhancer of split 2 (Drosophila)0.209
Csf1colony stimulating factor 1 (macrophage)0.190
Ccr2chemokine (C-C motif) receptor 20.183
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.164
S100a8S100 calcium binding protein A80.164
Hoxa2homeo box A20.162
Klrd1killer cell lectin-like receptor, subfamily D, member 10.159
RT1-EC2RT1 class Ib, locus EC20.151
Ptafrplatelet-activating factor receptor0.151
LOC100363783rCG53773-like0.150
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.139
Igsf6immunoglobulin superfamily, member 60.133
Ncr1natural cytotoxicity triggering receptor 10.133
Cd14CD14 molecule0.124
Il1rninterleukin 1 receptor antagonist0.124
Metmet proto-oncogene0.123
Cd8aCD8a molecule0.122
Ccl4chemokine (C-C motif) ligand 40.121
Ceacam10carcinoembryonic antigen-related cell adhesion molecule 100.121
Adora2aadenosine A2a receptor0.120
Vom2r27vomeronasal 2 receptor, 270.119
Ccl3chemokine (C-C motif) ligand 30.117
Scn11asodium channel, voltage-gated, type XI, alpha0.116
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.115
Cxcl2chemokine (C-X-C motif) ligand 20.114
Calcrlcalcitonin receptor-like0.113
Gzmbgranzyme B0.112
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.110
Il6interleukin 60.105
RGD1559588similar to cell surface receptor FDFACT0.105
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.104
Cd86CD86 molecule0.103
Havcr1hepatitis A virus cellular receptor 10.097
Aif1allograft inflammatory factor 10.095
Oas1a2'-5' oligoadenylate synthetase 1A0.091
Il1r1interleukin 1 receptor, type I0.091
Trim47tripartite motif-containing 470.091
Aqp8aquaporin 80.088
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.087
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.086
Pdynprodynorphin0.085
Ltbrlymphotoxin beta receptor (TNFR superfamily, member 3)0.085
Fosl1fos-like antigen 10.081
Sellselectin L0.080
Flt1FMS-related tyrosine kinase 10.080
Fgfr2fibroblast growth factor receptor 20.078
RGD1306474similar to RIKEN cDNA 9530003J230.077
Ugt2b7UDP glucuronosyltransferase 2 family, polypeptide B70.076
Dgkgdiacylglycerol kinase, gamma0.076
Apoa5apolipoprotein A-V0.076
Gstm3glutathione S-transferase mu 30.075
Tnfsf4tumor necrosis factor (ligand) superfamily, member 40.074
Il4interleukin 40.072
Cd5Cd5 molecule0.072
Edn1endothelin 10.072
Ccr1chemokine (C-C motif) receptor 10.072
Cfbcomplement factor B0.070
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.070
Mmp12matrix metallopeptidase 120.069
Olr226olfactory receptor 2260.069
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.069
Mmp3matrix metallopeptidase 30.068
S1pr2sphingosine-1-phosphate receptor 20.068
Bst1bone marrow stromal cell antigen 10.067
Fam70bfamily with sequence similarity 70, member B0.067
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.067
Cckarcholecystokinin A receptor0.067
Prf1perforin 1 (pore forming protein)0.066
Adam7ADAM metallopeptidase domain 70.066
Stip1stress-induced phosphoprotein 10.065
Lpllipoprotein lipase0.065
Tfectranscription factor EC0.063
Clec4fC-type lectin domain family 4, member f0.063
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.063
FaslgFas ligand (TNF superfamily, member 6)0.062
Crhbpcorticotropin releasing hormone binding protein0.061
Ptpreprotein tyrosine phosphatase, receptor type, E0.061
Tgm1transglutaminase 1, K polypeptide0.061
Cd2Cd2 molecule0.059
Slco2b1solute carrier organic anion transporter family, member 2b10.058
Oprm1opioid receptor, mu 10.058
Padi1peptidyl arginine deiminase, type I0.058
Adra1badrenergic, alpha-1B-, receptor0.057
Cficomplement factor I0.057
Lcn2lipocalin 20.056
C1rcomplement component 1, r subcomponent0.056
Rgs1regulator of G-protein signaling 10.056
Rod1ROD1 regulator of differentiation 1 (S. pombe)0.056
Gpx3glutathione peroxidase 30.056
Olr1496olfactory receptor 14960.056
Zfp36zinc finger protein 360.055
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
C52E12.4Protein C52E12.40.043
unc-94Protein UNC-940.030
sax-3Protein SAX-30.030
glh-1Protein GLH-10.028
egl-27Protein EGL-270.027
Y22D7AL.10Protein Y22D7AL.100.027
sur-2Protein SUR-20.026
ceh-44Protein CEH-440.024
unc-32Protein UNC-320.024
dmd-6Protein DMD-60.022
egl-30Protein EGL-300.021
eat-4Protein EAT-40.019
F41C3.8Protein F41C3.80.018
glr-5Protein GLR-50.018
ser-3Protein SER-30.017
egl-18Protein EGL-180.016
pptr-2Protein PPTR-20.016
frm-4Protein FRM-40.015
Y44E3A.6Protein Y44E3A.60.015
cat-2Protein CAT-20.014
eea-1Protein EEA-10.014
nrde-3Protein NRDE-30.014
flh-2Protein FLH-20.013
par-5Protein PAR-50.013
cat-1Protein CAT-10.012
frm-10Protein FRM-100.012
sta-1Protein STA-10.012
pqe-1Protein PQE-10.012
psf-1Protein PSF-10.012
K10D6.4Protein K10D6.40.012
prg-2Protein PRG-20.012
bec-1Protein BEC-10.012
sel-2Protein SEL-20.011
let-60Protein LET-600.011
clp-2Protein CLP-20.011
C09F5.1Protein C09F5.10.011
ZC328.3Protein ZC328.30.011
lin-25Protein LIN-250.011
sek-1Protein SEK-10.010
cam-1Protein CAM-10.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ef1aelongation factor 1-alpha0.705
pdcd2programmed cell death 20.456
chukconserved helix-loop-helix ubiquitous kinase0.301
mpxmyeloid-specific peroxidase0.218
cyt1type I cytokeratin, enveloping layer0.215
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.185
epas1bendothelial PAS domain protein 1b0.181
cpceruloplasmin0.180
mmp9matrix metalloproteinase 90.167
ripk2receptor-interacting serine-threonine kinase 20.141
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.138
nod1nucleotide-binding oligomerization domain containing 10.112
pcsk2proprotein convertase subtilisin/kexin type 20.106
nanos3nanos homolog 30.100
LOC557072caspase recruitment domain-containing protein 11-like0.100
ip6k2inositol hexaphosphate kinase 20.099
lppLIM domain containing preferred translocation partner in lipoma0.098
pglyrp5peptidoglycan recognition protein 50.098
tlr9toll-like receptor 90.096
rbp4retinol binding protein 4, plasma0.094
stc1lstanniocalcin 1, like0.090
tnfatumor necrosis factor a (TNF superfamily, member 2)0.089
adrb2aadrenergic receptor, beta 2a0.081
tagln2transgelin 20.080
fgfr3fibroblast growth factor receptor 30.078
fabp11afatty acid binding protein 11a0.072
eporerythropoietin receptor0.071
il8interleukin 80.068
igf1rainsulin-like growth factor 1a receptor0.066
fn1fibronectin 10.062
cry1acryptochrome 1a0.062
gngt1guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 10.061
pcsk9proprotein convertase subtilisin/kexin type 90.061
axin2axin 2 (conductin, axil)0.060
tlr21toll-like receptor 210.056
tgm2btransglutaminase 2b0.056
mcoln1mucolipin 10.055
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.054
sh3gl1bSH3-domain GRB2-like 1b0.054
pycardPYD and CARD domain containing0.052
rhagRhesus blood group-associated glycoprotein0.052
atf3activating transcription factor 30.050
efnb3bephrin B3b0.050
ctsl1acathepsin L, 1 a0.048
rhcgbRhesus blood group, C glycoprotein b0.043
smc1alstructural maintenance of chromosomes 1A, like0.043
gcm2glial cells missing homolog 2 (Drosophila)0.042
alpalkaline phosphatase0.041
bhmtbetaine-homocysteine methyltransferase0.041
cps1carbamoyl-phosphate synthase 1, mitochondrial0.040
lyzlysozyme0.037
mtpmicrosomal triglyceride transfer protein0.037
foxi3bforkhead box I3b0.036
ctsbacathepsin B, a0.035
LOC100000934hypothetical protein LOC1000009340.034
avplarginine vasopressin-like0.034
mmp13amatrix metalloproteinase 13a0.034
il6rinterleukin 6 receptor0.033
tnfbtumor necrosis factor b (TNF superfamily, member 2)0.032
ptger2aprostaglandin E receptor 2a (subtype EP2)0.032
msi1musashi homolog 1 (Drosophila)0.032
ptger4bprostaglandin E receptor 4 (subtype EP4) b0.032
psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.032
vasavasa homolog0.031
plgplasminogen0.031
copg2coatomer protein complex, subunit gamma 20.031
si:dkey-76b14.4si:dkey-76b14.40.031
caspacaspase a0.030
ptgs1prostaglandin-endoperoxide synthase 10.029
zgc:171802zgc:1718020.029
junbjun B proto-oncogene0.029
il1binterleukin 1, beta and interleukin 1, beta0.028
pglyrp6peptidoglycan recognition protein 60.028
oprk1opioid receptor, kappa 10.028
relv-rel reticuloendotheliosis viral oncogene homolog0.027
tlr4bbtoll-like receptor 4b, duplicate b0.027
arrb2barrestin, beta 2b0.027
sp2sp2 transcription factor0.026
setd7SET domain containing (lysine methyltransferase) 70.025
c1qbcomplement component 1, q subcomponent, B chain0.025
spry4sprouty (Drosophila) homolog 40.025
serpinb1serpin peptidase inhibitor, clade B (ovalbumin), member 10.024
tbx1T-box 10.024
rpl37ribosomal protein L370.024
npy7rneuropeptide Y receptor Y70.024
hmgcrb3-hydroxy-3-methylglutaryl-Coenzyme A reductase b0.024
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.024
fn1bfibronectin 1b0.024
cd40lgCD40 ligand0.023
zgc:123282zgc:1232820.023
dab1adisabled homolog 1a (Drosophila)0.023
bhlhe40basic helix-loop-helix family, member e400.022
prkczprotein kinase C, zeta0.022
si:ch211-195h23.3si:ch211-195h23.30.022
bmp2bbone morphogenetic protein 2b0.022
si:ch1073-351m12.1si:ch1073-351m12.10.022
gata5GATA-binding protein 50.022
LOC566708FL cytokine receptor-like0.022
wlswntless homolog (Drosophila)0.022
tlr18toll-like receptor 180.022
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
RelRelish0.995
AttAAttacin-A0.990
PGRP-LCPeptidoglycan recognition protein LC0.982
DptBDiptericin B0.971
PGRP-SAPeptidoglycan recognition protein SA0.951
grassGram-positive Specific Serine protease0.902
spzspatzle0.865
Spn27ASerpin 27A0.864
PGRP-SDCG7496 gene product from transcript CG7496-RA0.850
Atg1Autophagy-specific gene 10.828
CycECyclin E0.811
cactcactus0.796
CG6361CG6361 gene product from transcript CG6361-RA0.753
Sp7Serine protease 70.749
fonfondue0.689
MtkMetchnikowin0.654
BG4CG12297 gene product from transcript CG12297-RA0.645
TimpTissue inhibitor of metalloproteases0.643
egreiger0.635
DreddDeath related ced-3/Nedd2-like protein0.582
Mpk2CG5475 gene product from transcript CG5475-RB0.568
EcREcdysone receptor0.559
HsfHeat shock factor0.546
SPESpatzle-Processing Enzyme0.541
rlrolled0.511
LysDLysozyme D0.484
keykenny0.468
LysELysozyme E0.439
CG13422CG13422 gene product from transcript CG13422-RA0.438
CG15917CG15917 gene product from transcript CG15917-RA0.436
rev7CG2948 gene product from transcript CG2948-RA0.421
imdimmune deficiency0.416
oskoskar0.404
ird5immune response deficient 50.401
PGRP-LFPeptidoglycan recognition protein LF0.381
CG40127CG40127 gene product from transcript CG40127-RA0.377
stumpsCG31317 gene product from transcript CG31317-RC0.368
dcodiscs overgrown0.366
foxoforkhead box, sub-group O0.341
MedMedea0.338
IrcImmune-regulated catalase0.325
CG15065CG15065 gene product from transcript CG15065-RA0.320
EgfrEpidermal growth factor receptor0.316
modSPmodular serine protease0.305
bratbrain tumor0.300
PGRP-SC1aCG14746 gene product from transcript CG14746-RA0.299
CG32185CG32185 gene product from transcript CG32185-RA0.287
Spn1Serine protease inhibitor 10.283
PGRP-LBPeptidoglycan recognition protein LB0.283
Nrx-IVNeurexin IV0.281
TM9SF4CG7364 gene product from transcript CG7364-RA0.276
Traf4TNF-receptor-associated factor 40.267
Mmp1Matrix metalloproteinase 10.265
CG16718CG16718 gene product from transcript CG16718-RA0.260
Myd88CG2078 gene product from transcript CG2078-RA0.259
ththread0.258
StamSignal transducing adaptor molecule0.256
GltGlutactin0.248
Trx-2thioredoxin-20.245
Top2Topoisomerase 20.238
pirkpoor Imd response upon knock-in0.233
CG31038CG31038 gene product from transcript CG31038-RA0.233
maelmaelstrom0.230
Spn28DSerpin 28D0.228
lwrlesswright0.225
PGRP-SC2CG14745 gene product from transcript CG14745-RA0.225
IM18Immune induced molecule 180.213
IM10Immune induced molecule 100.209
Rbp6RNA-binding protein 60.208
CG9014CG9014 gene product from transcript CG9014-RA0.207
saxsaxophone0.204
ovoCG6824 gene product from transcript CG6824-RE0.203
CG2199CG2199 gene product from transcript CG2199-RB0.202
GNBP3Gram-negative bacteria binding protein 30.200
tubtube0.196
CG18666CG18666 gene product from transcript CG18666-RA0.195
CG42863CG42863 gene product from transcript CG42863-RB0.195
beta'Copbeta'-coatomer protein0.193
LysBLysozyme B0.193
bazbazooka0.192
DptDiptericin0.190
DrsDrosomycin0.188
CatCatalase0.186
CG7910CG7910 gene product from transcript CG7910-RA0.185
ird1immune response deficient 10.183
PGRP-SB1CG9681 gene product from transcript CG9681-RA0.181
wgwingless0.180
AttCAttacin-C0.179
koiklaroid0.177
ThorCG8846 gene product from transcript CG8846-RA0.171
eaterCG6124 gene product from transcript CG6124-RB0.171
Dcr-2Dicer-20.169
mbcmyoblast city0.167
panpangolin0.167
Ptp69DProtein tyrosine phosphatase 69D0.165
Rho1CG8416 gene product from transcript CG8416-RB0.163
LysCLysozyme C0.163
CG18594CG18594 gene product from transcript CG18594-RA0.163
pumpumilio0.162
CG5794CG5794 gene product from transcript CG5794-RB0.162
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)1.000
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.999
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.999
MYD88myeloid differentiation primary response gene (88)0.999
TNFAIP3tumor necrosis factor, alpha-induced protein 30.999
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.995
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.994
IRAK1interleukin-1 receptor-associated kinase 10.993
TRAF6TNF receptor-associated factor 60.991
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.988
IL8interleukin 80.965
CASP8caspase 8, apoptosis-related cysteine peptidase0.961
MDM2Mdm2 p53 binding protein homolog (mouse)0.960
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.956
B2Mbeta-2-microglobulin0.951
S100BS100 calcium binding protein B0.941
IL1Binterleukin 1, beta0.937
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.935
ICAM1intercellular adhesion molecule 10.933
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.933
CXCL2chemokine (C-X-C motif) ligand 20.929
IFIT3interferon-induced protein with tetratricopeptide repeats 30.929
UBCubiquitin C0.927
ESR1estrogen receptor 10.916
PTPN1protein tyrosine phosphatase, non-receptor type 10.916
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.897
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.891
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.891
SMAD4SMAD family member 40.888
EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 20.886
GHRgrowth hormone receptor0.873
MAP3K7mitogen-activated protein kinase kinase kinase 70.861
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.853
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.842
BIRC3baculoviral IAP repeat containing 30.833
HLA-DRB1major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 10.831
CXCL3chemokine (C-X-C motif) ligand 30.830
CXCL10chemokine (C-X-C motif) ligand 100.829
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.826
TNFSF10tumor necrosis factor (ligand) superfamily, member 100.815
IFI44interferon-induced protein 440.799
LILRB3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.788
C1Scomplement component 1, s subcomponent0.783
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.781
SOCS3suppressor of cytokine signaling 30.778
TLR2toll-like receptor 20.775
TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.773
RIPK2receptor-interacting serine-threonine kinase 20.767
BCL3B-cell CLL/lymphoma 30.745
HLA-Amajor histocompatibility complex, class I, A0.745
PLAURplasminogen activator, urokinase receptor0.744
NCOR2nuclear receptor corepressor 20.740
TNFtumor necrosis factor0.735
HLA-Bmajor histocompatibility complex, class I, B0.732
MAP3K5mitogen-activated protein kinase kinase kinase 50.730
S100A9S100 calcium binding protein A90.729
IFIT2interferon-induced protein with tetratricopeptide repeats 20.720
IFIT1interferon-induced protein with tetratricopeptide repeats 10.716
IFIH1interferon induced with helicase C domain 10.714
HCKhemopoietic cell kinase0.713
TRIM22tripartite motif containing 220.710
S100A8S100 calcium binding protein A80.707
SQSTM1sequestosome 10.685
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.680
PTAFRplatelet-activating factor receptor0.678
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.671
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.669
FGF1fibroblast growth factor 1 (acidic)0.666
HLA-Cmajor histocompatibility complex, class I, C0.657
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.654
MED15mediator complex subunit 150.654
S100A6S100 calcium binding protein A60.653
CD14CD14 molecule0.652
OAS22'-5'-oligoadenylate synthetase 2, 69/71kDa0.645
CCR1chemokine (C-C motif) receptor 10.643
CHUKconserved helix-loop-helix ubiquitous kinase0.639
DICER1dicer 1, ribonuclease type III0.634
IRF7interferon regulatory factor 70.627
DDX60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.625
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.614
PYCARDPYD and CARD domain containing0.613
CCL5chemokine (C-C motif) ligand 50.601
CCL4chemokine (C-C motif) ligand 40.598
MAPK1mitogen-activated protein kinase 10.592
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.590
STAT1signal transducer and activator of transcription 1, 91kDa0.588
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.588
RXRAretinoid X receptor, alpha0.582
IRF1interferon regulatory factor 10.579
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.551
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.550
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.548
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.544
PVRL1poliovirus receptor-related 1 (herpesvirus entry mediator C)0.529
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.527
MAPK14mitogen-activated protein kinase 140.524
PMLpromyelocytic leukemia0.522
PLSCR1phospholipid scramblase 10.521
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.520
OAS12',5'-oligoadenylate synthetase 1, 40/46kDa0.517
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tlr4toll-like receptor 41.000
Stat3signal transducer and activator of transcription 31.000
Casp4caspase 4, apoptosis-related cysteine peptidase0.999
Clockcircadian locomotor output cycles kaput0.999
Stat1signal transducer and activator of transcription 10.998
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.997
Casp1caspase 10.997
Tnftumor necrosis factor0.996
Traf6TNF receptor-associated factor 60.996
Lyz2lysozyme 20.996
Map3k7mitogen-activated protein kinase kinase kinase 70.996
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.995
Apoeapolipoprotein E0.994
Casp8caspase 80.988
Gbp2guanylate binding protein 20.984
Myd88myeloid differentiation primary response gene 880.982
Gbp7guanylate binding protein 70.982
C3complement component 30.980
Cd40CD40 antigen0.971
Ikbkginhibitor of kappaB kinase gamma0.970
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.970
Tnfaip3tumor necrosis factor, alpha-induced protein 30.967
Birc3baculoviral IAP repeat-containing 30.964
Il10rainterleukin 10 receptor, alpha0.962
Batfbasic leucine zipper transcription factor, ATF-like0.960
Irf7interferon regulatory factor 70.960
Irf1interferon regulatory factor 10.959
Map3k8mitogen-activated protein kinase kinase kinase 80.954
Stat6signal transducer and activator of transcription 60.953
Klrk1killer cell lectin-like receptor subfamily K, member 10.949
Slamf1signaling lymphocytic activation molecule family member 10.947
Mapk14mitogen-activated protein kinase 140.946
Iigp1interferon inducible GTPase 10.946
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.945
Gbp3guanylate binding protein 30.942
Pax8paired box gene 80.941
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.940
Trim21tripartite motif-containing 210.939
Il1binterleukin 1 beta0.937
Il4rainterleukin 4 receptor, alpha0.935
Smad4MAD homolog 4 (Drosophila)0.934
Ifi203interferon activated gene 2030.931
Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 10.926
Parp14poly (ADP-ribose) polymerase family, member 140.920
Chrnb2cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)0.919
Atf2activating transcription factor 20.919
Irgm1immunity-related GTPase family M member 10.919
Ikbkbinhibitor of kappaB kinase beta0.917
Nlrp3NLR family, pyrin domain containing 30.914
Gzmkgranzyme K0.912
AxlAXL receptor tyrosine kinase0.899
FaslFas ligand (TNF superfamily, member 6)0.894
Cyldcylindromatosis (turban tumor syndrome)0.894
H2-K1histocompatibility 2, K1, K region0.893
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.893
Nos2nitric oxide synthase 2, inducible0.893
Aoahacyloxyacyl hydrolase0.893
Traf1TNF receptor-associated factor 10.892
Unc93b1unc-93 homolog B1 (C. elegans)0.885
JunbJun-B oncogene0.884
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.883
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.883
Map3k14mitogen-activated protein kinase kinase kinase 140.882
Trim30atripartite motif-containing 30A0.877
Il18r1interleukin 18 receptor 10.876
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.876
Ptgs2prostaglandin-endoperoxide synthase 20.875
FosFBJ osteosarcoma oncogene0.875
Ccl2chemokine (C-C motif) ligand 20.868
Pdcd1lg2programmed cell death 1 ligand 20.861
Cfhcomplement component factor h0.859
Il18rapinterleukin 18 receptor accessory protein0.850
Ptenphosphatase and tensin homolog0.850
Klra9killer cell lectin-like receptor subfamily A, member 90.845
Cxcl10chemokine (C-X-C motif) ligand 100.841
Egr2early growth response 20.833
Prdm1PR domain containing 1, with ZNF domain0.830
Ccl8chemokine (C-C motif) ligand 80.827
Arntlaryl hydrocarbon receptor nuclear translocator-like0.826
Irf9interferon regulatory factor 90.825
Il1rninterleukin 1 receptor antagonist0.823
H2-Q7histocompatibility 2, Q region locus 70.822
FasFas (TNF receptor superfamily member 6)0.820
Gzmbgranzyme B0.816
Ppargperoxisome proliferator activated receptor gamma0.816
Ctla4cytotoxic T-lymphocyte-associated protein 40.814
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.812
Icosinducible T-cell co-stimulator0.811
Cd33CD33 antigen0.811
Cd44CD44 antigen0.809
Pax2paired box gene 20.792
MefvMediterranean fever0.792
Il2rbinterleukin 2 receptor, beta chain0.790
Ddx60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.779
Ccr1chemokine (C-C motif) receptor 10.777
Cd180CD180 antigen0.768
Clec4nC-type lectin domain family 4, member n0.767
Per2period homolog 2 (Drosophila)0.761
Il10interleukin 100.759
Smad1MAD homolog 1 (Drosophila)0.758
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism