The network for 'pronephros morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pronephros morphogenesis

The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ntlano tail a0.766
osr2odd-skipped related 2 (Drosophila)0.761
tbx16T-box gene 160.747
hnf1baHNF1 homeobox Ba0.711
tbx2aT-box gene 2a0.595
bmp4bone morphogenetic protein 40.481
pax2apaired box gene 2a0.290
lhx1aLIM homeobox 1a0.273
flhfloating head0.213
wt1awilms tumor 1a0.169
her7hairy and enhancer of split related-70.165
ror2receptor tyrosine kinase-like orphan receptor 20.165
myl7myosin, light polypeptide 7, regulatory0.142
fgf8afibroblast growth factor 8 a0.137
shhasonic hedgehog a0.117
aldh1a2aldehyde dehydrogenase 1 family, member A20.116
her1hairy-related 10.116
hnf1bbHNF1 homeobox Bb0.116
gbx2gastrulation brain homeo box 20.114
eng2aengrailed 2a0.104
lrrc6leucine rich repeat containing 60.102
wt1bwilms tumor 1b0.091
irx4biroquois homeobox protein 4b0.089
tll1tolloid-like 10.084
cyp26a1cytochrome P450, subfamily XXVIA, polypeptide 10.084
hapln1ahyaluronan and proteoglycan link protein 1a0.065
snai1asnail homolog 1a (Drosophila)0.065
tbx2bT-box 2b0.064
pmaip1phorbol-12-myristate-13-acetate-induced protein 10.061
rxraaretinoid X receptor, alpha a0.060
tbx20T-box 200.058
ndr1nodal-related 10.056
sox9aSRY-box containing gene 9a0.053
prrx1bpaired related homeobox 1b0.053
pou3f3bPOU class 3 homeobox 3b0.053
sept6septin 60.053
vsx1visual system homeobox 1 homolog, chx10-like0.051
vcanbversican b0.050
bbs7Bardet-Biedl syndrome 70.050
hoxd12ahomeo box D12a0.049
sox10SRY-box containing gene 100.048
hoxa11bhomeo box A11b0.047
msgn1mesogenin 10.046
hoxa9bhomeo box A9b0.045
lrrc50leucine rich repeat containing 500.045
hoxd11ahomeo box D11a0.044
notch1anotch homolog 1a0.043
jag2jagged 20.043
ttc21btetratricopeptide repeat domain 21B0.041
map9microtubule-associated protein 90.041
eomesaeomesodermin homolog a0.041
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.040
has2hyaluronan synthase 20.039
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.039
igf1rbinsulin-like growth factor 1b receptor0.039
ift52intraflagellar transport protein 520.037
mibmind bomb0.036
lnpalimb and neural patterns a0.036
mmp2matrix metalloproteinase 20.035
arl13bADP-ribosylation factor-like 13b0.035
myod1myogenic differentiation 10.034
cdx4caudal type homeo box transcription factor 40.034
mbtps1membrane-bound transcription factor protease, site 10.034
dccdeleted in colorectal carcinoma0.034
sema3dsemaphorin 3d0.033
irx1airoquois homeobox protein 1, a0.033
rbpjarecombination signal binding protein for immunoglobulin kappa J region a0.032
ccdc40coiled-coil domain containing 400.032
tcf21transcription factor 210.031
hoxa10bhomeo box A10b0.031
hmx4H6 family homeobox 40.030
hand2heart and neural crest derivatives expressed transcript 20.030
metap2methionyl aminopeptidase 20.029
myf5myogenic factor 50.029
nkx2.5NK2 transcription factor related 50.028
gstt1bglutathione S-transferase theta 1b0.028
grnbgranulin b0.028
wnt9awingless-type MMTV integration site family, member 9A0.027
gon4lgon-4-like (C.elegans)0.027
sp5lSp5 transcription factor-like0.027
hoxa13ahomeo box A13a0.027
dlx6adistal-less homeobox gene 6a0.026
prox2prospero homeobox 20.026
fgf10afibroblast growth factor 10a0.026
stk36serine/threonine kinase 36 (fused homolog, Drosophila)0.025
pax8paired box gene 80.025
pcdh8protocadherin 80.025
osr1odd-skipped related 1 (Drosophila)0.024
slc4a4asolute carrier family 4, member 4a0.024
smad9MAD homolog 9 (Drosophila)0.023
ncam1bneural cell adhesion molecule 1b0.023
snx1sorting nexin 10.023
neurod6bneurogenic differentiation 6b0.023
bmp2bbone morphogenetic protein 2b0.023
rxrbaretinoid x receptor, beta a0.023
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HNF4Ahepatocyte nuclear factor 4, alpha0.318
PKD1polycystic kidney disease 1 (autosomal dominant)0.123
PCBD1pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha0.018
PAMpeptidylglycine alpha-amidating monooxygenase0.017
PCBD2pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 20.016
CRIM1cysteine rich transmembrane BMP regulator 1 (chordin-like)0.015
TRPC1transient receptor potential cation channel, subfamily C, member 10.012
HNF1BHNF1 homeobox B0.011
NKTRnatural killer-tumor recognition sequence0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog0.909
Rargretinoic acid receptor, gamma0.892
Pax3paired box gene 30.858
Foxc1forkhead box C10.854
Tbx1T-box 10.826
Hoxa1homeobox A10.825
Jag1jagged 10.768
Fgfr2fibroblast growth factor receptor 20.764
Eya1eyes absent 1 homolog (Drosophila)0.760
Fgf8fibroblast growth factor 80.749
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.698
Foxc2forkhead box C20.601
Pitx2paired-like homeodomain transcription factor 20.588
Fgfr1fibroblast growth factor receptor 10.545
Foxg1forkhead box G10.529
Chd7chromodomain helicase DNA binding protein 70.521
Bmp4bone morphogenetic protein 40.487
Vangl2vang-like 2 (van gogh, Drosophila)0.464
Emx2empty spiracles homolog 2 (Drosophila)0.448
Gbx2gastrulation brain homeobox 20.442
Gli3GLI-Kruppel family member GLI30.380
Rarbretinoic acid receptor, beta0.337
Mks1Meckel syndrome, type 10.329
Lhx1LIM homeobox protein 10.305
Smosmoothened homolog (Drosophila)0.290
Rararetinoic acid receptor, alpha0.268
Rxraretinoid X receptor alpha0.207
Otx1orthodenticle homolog 1 (Drosophila)0.205
Zeb1zinc finger E-box binding homeobox 10.175
Otx2orthodenticle homolog 2 (Drosophila)0.161
Ednraendothelin receptor type A0.156
Gata3GATA binding protein 30.150
Efnb2ephrin B20.135
Ece1endothelin converting enzyme 10.122
Pkd1polycystic kidney disease 1 homolog0.121
Bicc1bicaudal C homolog 1 (Drosophila)0.117
Tbx10T-box 100.101
Hoxa3homeobox A30.100
Sox2SRY-box containing gene 20.095
Fgf10fibroblast growth factor 100.092
Pax2paired box gene 20.086
Tgfb2transforming growth factor, beta 20.083
Prrx2paired related homeobox 20.078
Vegfavascular endothelial growth factor A0.071
Bmp7bone morphogenetic protein 70.065
Isl1ISL1 transcription factor, LIM/homeodomain0.057
Tcfap2atranscription factor AP-2, alpha0.056
Sox9SRY-box containing gene 90.054
Dlx5distal-less homeobox 50.049
Hes1hairy and enhancer of split 1 (Drosophila)0.048
Tgfbr2transforming growth factor, beta receptor II0.040
Hand2heart and neural crest derivatives expressed transcript 20.039
Gli2GLI-Kruppel family member GLI20.036
Meox2mesenchyme homeobox 20.026
Rdh10retinol dehydrogenase 10 (all-trans)0.026
Retret proto-oncogene0.026
Fgf3fibroblast growth factor 30.024
Sox11SRY-box containing gene 110.023
Pax8paired box gene 80.022
Hmx3H6 homeobox 30.021
Tctn1tectonic family member 10.021
Ctnnb1catenin (cadherin associated protein), beta 10.020
Acvr1activin A receptor, type 10.020
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.019
Lmx1aLIM homeobox transcription factor 1 alpha0.019
Fgfr3fibroblast growth factor receptor 30.019
Wt1Wilms tumor 1 homolog0.019
Sox4SRY-box containing gene 40.017
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.016
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.016
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.015
Nrp1neuropilin 10.015
Prrx1paired related homeobox 10.015
Wnt9bwingless-type MMTV integration site 9B0.015
Psen1presenilin 10.014
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.014
Fbln1fibulin 10.014
Cited2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.014
Gscgoosecoid homeobox0.013
Cys1cystin 10.013
Pbx1pre B-cell leukemia transcription factor 10.013
Megf8multiple EGF-like-domains 80.012
Hoxa2homeobox A20.011
Wnt5awingless-related MMTV integration site 5A0.011
Hoxb3homeobox B30.011
Bcl2B-cell leukemia/lymphoma 20.011
Bdnfbrain derived neurotrophic factor0.010
Hoxd11homeobox D110.010
Pax6paired box gene 60.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism