The network for 'proteasome mediated ubiquitin dependent protein catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

proteasome mediated ubiquitin dependent protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

NameDescriptionProbabilityFunc Analog Organism
Psma5proteasome (prosome, macropain) subunit, alpha type 50.995
Psma7proteasome (prosome, macropain) subunit, alpha type 70.975
Psma3proteasome (prosome, macropain) subunit, alpha type 30.949
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.814
Psmb3proteasome (prosome, macropain) subunit, beta type 30.797
Psma4proteasome (prosome, macropain) subunit, alpha type 40.793
Psma2proteasome (prosome, macropain) subunit, alpha type 20.467
Psmb4proteasome (prosome, macropain) subunit, beta type 40.391
Psmb10proteasome (prosome, macropain) subunit, beta type 100.372
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.337
Psmb2proteasome (prosome, macropain) subunit, beta type 20.334
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.292
Psmb6proteasome (prosome, macropain) subunit, beta type 60.287
Psmb1proteasome (prosome, macropain) subunit, beta type 10.232
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.196
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.187
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.168
Psmb7proteasome (prosome, macropain) subunit, beta type 70.164
Ufd1lubiquitin fusion degradation 1 like (yeast)0.143
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.123
Psmd7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.116
Psme2proteasome (prosome, macropain) activator subunit 20.098
Mgat2mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase0.080
Ppp1r2protein phosphatase 1, regulatory (inhibitor) subunit 20.066
Ptges3prostaglandin E synthase 3 (cytosolic)0.057
Rgs19regulator of G-protein signaling 190.056
Arf1ADP-ribosylation factor 10.056
Rbbp7retinoblastoma binding protein 70.052
Ube2cubiquitin-conjugating enzyme E2C0.052
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.049
Ube2iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.047
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.043
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.043
Pdia4protein disulfide isomerase family A, member 40.040
Cand1cullin-associated and neddylation-dissociated 10.040
CnbpCCHC-type zinc finger, nucleic acid binding protein0.037
Pompproteasome maturation protein0.036
Foxm1forkhead box M10.035
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.035
Hspa5heat shock protein 50.032
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.032
Ghitmgrowth hormone inducible transmembrane protein0.029
Rab11aRAB11a, member RAS oncogene family0.028
Eef2eukaryotic translation elongation factor 20.028
Nsfl1cNSFL1 (p97) cofactor (p47)0.027
Btg1B-cell translocation gene 1, anti-proliferative0.026
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.024
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.024
Txnl1thioredoxin-like 10.024
Kif22kinesin family member 220.023
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.023
Mapre1microtubule-associated protein, RP/EB family, member 10.023
Cdca3cell division cycle associated 30.023
Ccnb1cyclin B10.022
Plk1polo-like kinase 1 (Drosophila)0.021
Ifrd1interferon-related developmental regulator 10.021
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.020
Hsp90b1heat shock protein 90, beta, member 10.020
Phaxphosphorylated adaptor for RNA export0.020
LOC687711similar to small nuclear ribonucleoprotein D30.020
Dnm1ldynamin 1-like0.019
Slc35b1solute carrier family 35, member B10.018
Syngr2synaptogyrin 20.017
Gopcgolgi associated PDZ and coiled-coil motif containing0.017
Vcpvalosin-containing protein0.016
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.016
Eif5aeukaryotic translation initiation factor 5A0.015
Rpl36ribosomal protein L360.015
Stx12syntaxin 120.015
Manfmesencephalic astrocyte-derived neurotrophic factor0.015
Thoc7THO complex 7 homolog (Drosophila)0.015
Rbm8aRNA binding motif protein 8A0.014
Top2atopoisomerase (DNA) II alpha0.014
Ube2d2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)0.014
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.014
Dnajb11DnaJ (Hsp40) homolog, subfamily B, member 110.014
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.013
Akt2v-akt murine thymoma viral oncogene homolog 20.013
Zfand5zinc finger, AN1-type domain 50.013
Traf4af1TRAF4 associated factor 10.013
Psmd8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.012
Higd1aHIG1 hypoxia inducible domain family, member 1A0.012
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.012
Tomm20translocase of outer mitochondrial membrane 20 homolog (yeast)0.012
Psmd14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.011
Arf4ADP-ribosylation factor 40.011
Cops2COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)0.011
Rad23bRAD23 homolog B (S. cerevisiae)0.011
Psma6proteasome (prosome, macropain) subunit, alpha type 60.011
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.011
Pdrg1p53 and DNA damage regulated 10.011
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.010
Rnaseh2aribonuclease H2, subunit A0.010
Ube2aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.010
Dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.010
Cd82Cd82 molecule0.010
Sumo1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
pas-4Protein PAS-40.616
rpn-7Protein RPN-70.610
pas-2Protein PAS-20.512
pbs-3Protein PBS-30.406
rpn-12Protein RPN-120.372
rpn-3Protein RPN-30.353
npl-4.2Protein NPL-4.20.294
rpt-2Protein RPT-20.261
npl-4.1Protein NPL-4.10.259
rpt-5Protein RPT-50.225
rpt-3Protein RPT-30.183
R02F11.4Protein R02F11.40.154
pas-1Protein PAS-10.154
cul-1Protein CUL-10.151
pbs-5Protein PBS-50.144
ima-3Protein IMA-30.122
imb-2Protein IMB-20.120
pas-6Protein PAS-60.110
pbs-2Protein PBS-20.109
mdf-2Protein MDF-20.106
rpn-6.1Protein RPN-6.10.099
pbs-4Protein PBS-40.096
pbs-1Protein PBS-10.095
syx-17Protein SYX-170.092
atx-3Protein ATX-30.088
rpn-2Protein RPN-20.088
R11A8.7Protein R11A8.70.086
tba-2Protein TBA-20.079
app-1Protein APP-10.077
rpt-4Protein RPT-40.075
rnr-1Protein RNR-10.068
rpn-11Protein RPN-110.067
zyg-9Protein ZYG-90.058
mdt-8Protein MDT-80.056
pbs-7Protein PBS-70.055
cdc-48.2Protein CDC-48.20.054
egl-18Protein EGL-180.051
spd-5Protein SPD-50.049
pas-5Protein PAS-50.046
pcn-1Protein PCN-10.045
pbs-6Protein PBS-60.045
skr-1Protein SKR-10.044
dlc-1Protein DLC-10.043
hrp-1Protein HRP-10.041
taf-5Protein TAF-50.040
pas-7Protein PAS-70.040
CELE_C24H12.5Protein C24H12.50.038
dpy-30Protein DPY-300.037
trap-4Protein TRAP-40.036
gmeb-1Protein GMEB-10.035
ubc-3Protein UBC-30.035
bub-1Protein BUB-10.035
rod-1Protein ROD-10.033
dsh-2Protein DSH-20.031
T22F3.2Protein T22F3.20.031
snr-2Protein SNR-20.031
cdc-48.1Protein CDC-48.10.031
Y47D3A.29Protein Y47D3A.290.029
F49C12.9Protein F49C12.90.029
B0454.9Protein B0454.90.028
rpn-10Protein RPN-100.028
rpn-5Protein RPN-50.028
daf-1Protein DAF-10.027
ZK1248.11Protein ZK1248.110.027
vps-53Protein VPS-530.026
cam-1Protein CAM-10.026
lin-3Protein LIN-30.026
zen-4Protein ZEN-40.026
rpn-1Protein RPN-10.025
pap-1Protein PAP-10.025
cki-2Protein CKI-20.024
cdl-1Protein CDL-10.024
his-6Protein HIS-60.024
his-42Protein HIS-420.023
tag-256Protein TAG-2560.023
sel-12Protein SEL-120.023
klp-16Protein KLP-160.023
pmr-1Protein PMR-10.023
ZK507.6Protein ZK507.60.022
CELE_K08F4.1Protein K08F4.10.022
pup-2Protein PUP-20.022
gpr-2Protein GPR-20.022
CELE_B0334.5Protein B0334.50.022
CELE_T10C6.6Protein T10C6.60.022
CELE_Y57E12AL.6Protein Y57E12AL.60.022
par-5Protein PAR-50.021
rpt-1Protein RPT-10.021
rpn-9Protein RPN-90.021
tbb-2Protein TBB-20.021
rpt-6Protein RPT-60.021
snr-4Protein SNR-40.020
F08B4.7Protein F08B4.70.020
asb-1Protein ASB-10.020
W09D10.1Protein W09D10.10.020
hsr-9Protein HSR-90.020
psr-1Protein PSR-10.020
B0041.5Protein B0041.50.020
Y71H2AM.20Protein Y71H2AM.200.020
hda-1Protein HDA-10.019
F46F11.6Protein F46F11.60.019
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
psmb1proteasome (prosome, macropain) subunit, beta type, 10.959
psma8proteasome (prosome, macropain) subunit, alpha type, 80.905
psma6aproteasome (prosome, macropain) subunit, alpha type, 6a0.889
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.873
psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.865
psmb3proteasome (prosome, macropain) subunit, beta type, 30.782
ccnb1cyclin B10.755
psmb2proteasome (prosome, macropain) subunit, beta type, 20.704
psma4proteasome (prosome, macropain) subunit, alpha type, 40.687
psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.673
psmb4proteasome (prosome, macropain) subunit, beta type, 40.664
ccna2cyclin A20.663
psmb7proteasome (prosome, macropain) subunit, beta type, 70.662
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.647
kif23kinesin family member 230.615
psmc1bproteasome (prosome, macropain) 26S subunit, ATPase, 1b0.580
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.537
plk1polo-like kinase 1 (Drosophila)0.527
btg2B-cell translocation gene 20.506
vcpvalosin containing protein0.482
psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.481
maxmyc-associated factor X0.465
psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.461
hspa5heat shock protein 50.455
psmc3proteasome (prosome, macropain) 26S subunit, ATPase, 30.410
crklv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.399
psma1proteasome (prosome, macropain) subunit, alpha type, 10.393
usp5ubiquitin specific protease 50.373
ck2bcasein kinase 2 beta0.359
slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.356
sec24cSEC24 family, member C (S. cerevisiae)0.341
aurkbaurora kinase B0.334
psmb5proteasome (prosome, macropain) subunit, beta type, 50.332
bnip3lbBCL2/adenovirus E1B interacting protein 3-like b0.313
kpna4karyopherin alpha 4 (importin alpha 3)0.305
psmc1aproteasome (prosome, macropain) 26S subunit, ATPase, 1a0.305
baxabcl2-associated X protein, a0.286
psma6bproteasome (prosome, macropain) subunit, alpha type, 6b0.283
psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.282
prpf40aPRP40 pre-mRNA processing factor 40 homolog A (yeast)0.270
ciapin1cytokine induced apoptosis inhibitor 10.268
chukconserved helix-loop-helix ubiquitous kinase0.267
sirt1sirtuin (silent mating type information regulation 2 homolog) 10.265
adrm1badhesion regulating molecule 1b0.264
rtkn2rhotekin 20.261
psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.258
psma2proteasome (prosome, macropain) subunit, alpha type, 20.250
hspa4bheat shock protein 4b0.248
fxr2fragile X mental retardation, autosomal homolog 20.245
ywhabatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a0.240
dynlrb1dynein, light chain, roadblock-type 10.229
psmd4bproteasome (prosome, macropain) 26S subunit, non-ATPase, 4b0.229
cul1bcullin 1b0.225
myf5myogenic factor 50.223
acvr1bactivin A receptor, type IB0.221
cdc20cell division cycle 20 homolog0.221
rab1aRAB1A, member RAS oncogene family0.217
rbl1retinoblastoma-like 1 (p107)0.214
smad9MAD homolog 9 (Drosophila)0.213
gna13aguanine nucleotide binding protein (G protein), alpha 13a0.211
senp3aSUMO1/sentrin/SMT3 specific peptidase 3a0.208
plekha3pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 30.205
cnot6CCR4-NOT transcription complex, subunit 60.204
tfpi2tissue factor pathway inhibitor 20.203
dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.202
brd3abromodomain containing 3a0.198
mapkapk2amitogen-activated protein kinase-activated protein kinase 2a0.197
hyou1hypoxia up-regulated 10.197
shfm1split hand/foot malformation (ectrodactyly) type 10.196
glulbglutamate-ammonia ligase (glutamine synthase) b0.195
gtf2a1general transcription factor IIA, 10.195
ccnb2cyclin B20.193
ccnecyclin E0.186
psmb11proteasome (prosome, macropain) subunit, beta type, 110.184
tia1lcytotoxic granule-associated RNA binding protein 1, like0.184
cul3acullin 3a0.183
tia1cytotoxic granule-associated RNA binding protein 10.183
psmd11aproteasome (prosome, macropain) 216S subunit, non-ATPase, 11a0.182
hnrnpkheterogeneous nuclear ribonucleoprotein K0.180
fliiflightless I homolog (Drosophila)0.176
smad2MAD homolog 2 (Drosophila)0.175
dnaja2lDnaJ (Hsp40) homolog, subfamily A, member 2, like0.174
xrn15'-3' exoribonuclease 10.173
pppde1PPPDE peptidase domain containing 10.173
csnk1g2acasein kinase 1, gamma 2a0.173
ube2g2ubiquitin-conjugating enzyme E2G 20.171
glrx3glutaredoxin 30.170
setd7SET domain containing (lysine methyltransferase) 70.170
zfand2azinc finger, AN1-type domain 2A0.169
exoc3exocyst complex component 30.169
eif4heukaryotic translation initiation factor 4h0.169
bsdc1BSD domain containing 10.168
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Mov34CG3416 gene product from transcript CG3416-RA0.921
Rpn9CG10230 gene product from transcript CG10230-RB0.848
tefutelomere fusion0.819
Pros29Proteasome 29kD subunit0.816
Rpt3CG16916 gene product from transcript CG16916-RA0.796
Prosbeta2Proteasome beta2 subunit0.777
CG12321CG12321 gene product from transcript CG12321-RA0.770
CycBCyclin B0.760
Rpt4CG3455 gene product from transcript CG3455-RA0.744
CG13349CG13349 gene product from transcript CG13349-RA0.741
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.735
Rpt1CG1341 gene product from transcript CG1341-RA0.718
skpACG16983 gene product from transcript CG16983-RD0.675
Pros54Proteasome 54kD subunit0.624
Rpn6Proteasome p44.5 subunit0.623
UbcD2Ubiquitin conjugating enzyme 20.621
Tbp-1Tat-binding protein-10.612
dcodiscs overgrown0.601
Pros28.1Proteasome 28kD subunit 10.597
Rpn2CG11888 gene product from transcript CG11888-RA0.571
slmbsupernumerary limbs0.532
poloCG12306 gene product from transcript CG12306-RA0.504
Rpn1CG7762 gene product from transcript CG7762-RA0.504
Prosbeta3Proteasome beta3 subunit0.494
Rpn5CG1100 gene product from transcript CG1100-RA0.476
Prosbeta1Proteasome beta1 subunit0.454
IncenpInner centromere protein0.410
Prosbeta7Proteasome beta7 subunit0.370
ncdnon-claret disjunctional0.367
Rpn3Regulatory particle non-ATPase 30.355
Rpd3CG7471 gene product from transcript CG7471-RA0.334
Rpn7CG5378 gene product from transcript CG5378-RA0.329
Cap-GCG34438 gene product from transcript CG34438-RF0.288
Ras85DRas oncogene at 85D0.282
Rpn12CG4157 gene product from transcript CG4157-RA0.265
Rpn11CG18174 gene product from transcript CG18174-RA0.256
p53CG33336 gene product from transcript CG33336-RB0.246
Pros35Proteasome 35kD subunit0.240
Pros45CG1489 gene product from transcript CG1489-RA0.239
Fcp1CG12252 gene product from transcript CG12252-RA0.231
bratbrain tumor0.217
Cdc37CG12019 gene product from transcript CG12019-RA0.214
CycB3Cyclin B30.189
IswiImitation SWI0.159
Pros25Proteasome 25kD subunit0.152
Tak1TGF-beta activated kinase 10.150
Uch-L3Ubiquitin C-terminal hydrolase0.147
Cenp-CCG31258 gene product from transcript CG31258-RA0.142
wmdwing morphogenesis defect0.139
CG4603CG4603 gene product from transcript CG4603-RA0.138
UchUbiquitin carboxy-terminal hydrolase0.138
Prosalpha5Proteasome alpha5 subunit0.132
CSN5COP9 complex homolog subunit 50.127
swmsecond mitotic wave missing0.126
CycECyclin E0.123
CG6230CG6230 gene product from transcript CG6230-RA0.121
CG17331CG17331 gene product from transcript CG17331-RA0.111
Prosalpha7Proteasome alpha7 subunit0.111
cal1chromosome alignment defect 10.111
Prosbeta5Proteasome beta5 subunit0.107
RpS20Ribosomal protein S200.105
CG3223CG3223 gene product from transcript CG3223-RA0.101
jubAjuba LIM protein0.101
pr-set7CG3307 gene product from transcript CG3307-RC0.099
CG2046CG2046 gene product from transcript CG2046-RA0.099
fwdfour wheel drive0.098
CycACyclin A0.095
cdc16CG6759 gene product from transcript CG6759-RA0.093
ctpcut up0.092
CG32581CG32581 gene product from transcript CG32581-RB0.091
PsaPuromycin sensitive aminopeptidase0.090
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.089
CG6540CG6540 gene product from transcript CG6540-RA0.086
HcfHost cell factor0.086
CG9135CG9135 gene product from transcript CG9135-RB0.086
Sox14Sox box protein 140.084
RbfRetinoblastoma-family protein0.082
CG8290CG8290 gene product from transcript CG8290-RA0.081
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
UBCubiquitin C1.000
SKP1S-phase kinase-associated protein 11.000
PSMA2proteasome (prosome, macropain) subunit, alpha type, 21.000
VCPvalosin containing protein1.000
RNF11ring finger protein 111.000
CDC27cell division cycle 27 homolog (S. cerevisiae)0.999
PSMA6proteasome (prosome, macropain) subunit, alpha type, 60.999
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.998
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.998
PSMB7proteasome (prosome, macropain) subunit, beta type, 70.998
CDC20cell division cycle 20 homolog (S. cerevisiae)0.997
CUL1cullin 10.995
CUL3cullin 30.995
PSMA1proteasome (prosome, macropain) subunit, alpha type, 10.995
BTRCbeta-transducin repeat containing0.995
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.994
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.993
MDM2Mdm2 p53 binding protein homolog (mouse)0.990
PSMA3proteasome (prosome, macropain) subunit, alpha type, 30.990
SMAD2SMAD family member 20.990
POMPproteasome maturation protein0.987
CCNB1cyclin B10.984
SKP2S-phase kinase-associated protein 2 (p45)0.983
CDK2cyclin-dependent kinase 20.982
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.981
PSMB1proteasome (prosome, macropain) subunit, beta type, 10.980
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.980
TP53tumor protein p530.980
RB1retinoblastoma 10.980
RBX1ring-box 1, E3 ubiquitin protein ligase0.977
SMURF2SMAD specific E3 ubiquitin protein ligase 20.972
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.972
UBQLN1ubiquilin 10.968
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.964
ANAPC4anaphase promoting complex subunit 40.962
PSMA5proteasome (prosome, macropain) subunit, alpha type, 50.958
ATXN3ataxin 30.953
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.953
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.948
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.948
OTUB1OTU domain, ubiquitin aldehyde binding 10.947
UHRF2ubiquitin-like with PHD and ring finger domains 20.947
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.946
PSMB3proteasome (prosome, macropain) subunit, beta type, 30.944
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.944
PSMB2proteasome (prosome, macropain) subunit, beta type, 20.944
DCUN1D1DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)0.931
CCNA2cyclin A20.929
XIAPX-linked inhibitor of apoptosis0.928
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.926
BIRC2baculoviral IAP repeat containing 20.924
DERL1Der1-like domain family, member 10.920
AMFRautocrine motility factor receptor0.918
CUL2cullin 20.905
UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)0.905
UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)0.904
SSR1signal sequence receptor, alpha0.901
SMN1survival of motor neuron 1, telomeric0.891
ADRM1adhesion regulating molecule 10.889
SMAD3SMAD family member 30.878
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.877
YY1YY1 transcription factor0.877
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.876
PLK1polo-like kinase 10.862
PSMB4proteasome (prosome, macropain) subunit, beta type, 40.855
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.852
HDAC1histone deacetylase 10.845
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.844
CSNK1Ecasein kinase 1, epsilon0.839
DVL3dishevelled, dsh homolog 3 (Drosophila)0.826
MAP3K5mitogen-activated protein kinase kinase kinase 50.826
ARIH2ariadne homolog 2 (Drosophila)0.826
ANAPC11anaphase promoting complex subunit 110.822
NFE2L2nuclear factor (erythroid-derived 2)-like 20.822
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.819
HDAC2histone deacetylase 20.819
FBXO5F-box protein 50.818
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.816
TCEB1transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)0.815
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.812
HSPA13heat shock protein 70kDa family, member 130.806
PSME3proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)0.789
WWP1WW domain containing E3 ubiquitin protein ligase 10.788
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.788
UFD1Lubiquitin fusion degradation 1 like (yeast)0.788
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.785
ANAPC5anaphase promoting complex subunit 50.784
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.767
NCOR1nuclear receptor corepressor 10.765
GSK3Bglycogen synthase kinase 3 beta0.756
PSMB6proteasome (prosome, macropain) subunit, beta type, 60.750
SYVN1synovial apoptosis inhibitor 1, synoviolin0.747
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.745
BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)0.727
ANAPC7anaphase promoting complex subunit 70.721
NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)0.706
BRCA1breast cancer 1, early onset0.701
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.699
HUWE1HECT, UBA and WWE domain containing 10.699
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.689
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Psen1presenilin 11.000
Ctnnb1catenin (cadherin associated protein), beta 10.996
Trp53transformation related protein 530.995
Psmb7proteasome (prosome, macropain) subunit, beta type 70.984
Psma7proteasome (prosome, macropain) subunit, alpha type 70.975
Vcpvalosin containing protein0.962
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.950
Psma5proteasome (prosome, macropain) subunit, alpha type 50.943
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.926
Axin1axin 10.925
Psmb6proteasome (prosome, macropain) subunit, beta type 60.890
Ccne1cyclin E10.889
Per2period homolog 2 (Drosophila)0.874
Gsk3bglycogen synthase kinase 3 beta0.873
Clockcircadian locomotor output cycles kaput0.852
Hspa5heat shock protein 50.848
Psma1proteasome (prosome, macropain) subunit, alpha type 10.842
Bcl2B-cell leukemia/lymphoma 20.839
Psma2proteasome (prosome, macropain) subunit, alpha type 20.831
Ccnb1cyclin B10.826
Psma3proteasome (prosome, macropain) subunit, alpha type 30.824
Psma6proteasome (prosome, macropain) subunit, alpha type 60.824
Cdk1cyclin-dependent kinase 10.804
Arntlaryl hydrocarbon receptor nuclear translocator-like0.801
Mbd3methyl-CpG binding domain protein 30.798
Akt1thymoma viral proto-oncogene 10.779
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.772
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.747
Cry1cryptochrome 1 (photolyase-like)0.737
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.685
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.679
Notch1Notch gene homolog 1 (Drosophila)0.666
Smurf2SMAD specific E3 ubiquitin protein ligase 20.650
Dvl1dishevelled, dsh homolog 1 (Drosophila)0.645
Hif1ahypoxia inducible factor 1, alpha subunit0.618
Foxm1forkhead box M10.618
Mdm2transformed mouse 3T3 cell double minute 20.610
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.593
Skp1aS-phase kinase-associated protein 1A0.593
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.554
Appamyloid beta (A4) precursor protein0.540
Ptenphosphatase and tensin homolog0.534
Trp73transformation related protein 730.531
Bmi1Bmi1 polycomb ring finger oncogene0.528
Cul3cullin 30.476
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.474
Ngly1N-glycanase 10.474
Cops2COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)0.459
Atf4activating transcription factor 40.452
Per1period homolog 1 (Drosophila)0.449
Cry2cryptochrome 2 (photolyase-like)0.443
Psmd14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.434
Fgfr1fibroblast growth factor receptor 10.425
Arid1bAT rich interactive domain 1B (SWI-like)0.413
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.406
Ncoa3nuclear receptor coactivator 30.405
6330577E15RikRIKEN cDNA 6330577E15 gene0.404
Psmb4proteasome (prosome, macropain) subunit, beta type 40.391
Pompproteasome maturation protein0.388
Manfmesencephalic astrocyte-derived neurotrophic factor0.382
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.380
Cav1caveolin 1, caveolae protein0.380
Adrm1adhesion regulating molecule 10.376
Aampangio-associated migratory protein0.376
Ncor1nuclear receptor co-repressor 10.375
Psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.374
Rnf19aring finger protein 19A0.371
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.370
Rnf111ring finger 1110.366
Birc5baculoviral IAP repeat-containing 50.359
Vdac3voltage-dependent anion channel 30.356
Csnk1ecasein kinase 1, epsilon0.354
Psme4proteasome (prosome, macropain) activator subunit 40.342
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.340
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.338
Cops6COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)0.331
Dyrk1adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a0.327
Rnf11ring finger protein 110.323
Tab3TGF-beta activated kinase 1/MAP3K7 binding protein 30.315
Pcnaproliferating cell nuclear antigen0.313
Kif22kinesin family member 220.311
Usp9xubiquitin specific peptidase 9, X chromosome0.304
Yap1yes-associated protein 10.301
Smad7MAD homolog 7 (Drosophila)0.299
Ube2nubiquitin-conjugating enzyme E2N0.290
Ccna2cyclin A20.281
Prc1protein regulator of cytokinesis 10.280
Ranbp9RAN binding protein 90.279
Kif20akinesin family member 20A0.278
Stat3signal transducer and activator of transcription 30.275
Ubcubiquitin C0.275
Ube3aubiquitin protein ligase E3A0.270
Psma4proteasome (prosome, macropain) subunit, alpha type 40.258
Mdm4transformed mouse 3T3 cell double minute 40.257
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.254
Dab1disabled homolog 1 (Drosophila)0.252
Psmb5proteasome (prosome, macropain) subunit, beta type 50.247
Gclmglutamate-cysteine ligase, modifier subunit0.245
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
YLR352Whypothetical protein0.504
YNL155Whypothetical protein0.415