IMP: Integrative Multi-species Prediction

The network for 'ribonucleoprotein complex disassembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ribonucleoprotein complex disassembly

The disaggregation of a protein-RNA complex into its constituent components.

Rattus norvegicus

Name	Description	Probability	Func Analog Organism

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Caenorhabditis elegans

Name	Description	Probability	Func Analog Organism

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Danio rerio

Name	Description	Probability	Func Analog Organism

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Drosophila melanogaster

Name	Description	Probability
N	Notch	0.187
wg	wingless	0.101
Dl	Delta	0.076
l(2)NC136	lethal (2) NC136	0.073
phl	pole hole	0.068
Fas2	Fasciclin 2	0.062
CG6610	CG6610 gene product from transcript CG6610-RA	0.056
spi	spitz	0.055
gl	glass	0.053
Antp	Antennapedia	0.045
dx	deltex	0.039
Ras85D	Ras oncogene at 85D	0.034
ato	atonal	0.033
argos	CG4531 gene product from transcript CG4531-RA	0.033
Eph	Eph receptor tyrosine kinase	0.033
MED20	Mediator complex subunit 20	0.032
EcR	Ecdysone receptor	0.032
eIF5	CG9177 gene product from transcript CG9177-RE	0.030
bsk	basket	0.029
CG17486	CG17486 gene product from transcript CG17486-RB	0.029
lz	lozenge	0.028
fu	fused	0.027
CG34415	CG34415 gene product from transcript CG34415-RC	0.027
Tif-IA	CG3278 gene product from transcript CG3278-RA	0.026
Rcd1	Reduction in Cnn dots 1	0.026
CG3689	CG3689 gene product from transcript CG3689-RB	0.025
Sema-2a	CG4700 gene product from transcript CG4700-RC	0.025
Tl	Toll	0.025
CG7671	CG7671 gene product from transcript CG7671-RA	0.022
CG3887	CG3887 gene product from transcript CG3887-RA	0.020
CG3056	CG3056 gene product from transcript CG3056-RB	0.020
trsn	translin	0.019
gro	groucho	0.019
dpp	decapentaplegic	0.018
Pc	Polycomb	0.018
CG8924	CG8924 gene product from transcript CG8924-RB	0.018
spd-2	spindle defective 2	0.017
CG14749	CG14749 gene product from transcript CG14749-RA	0.017
CG2862	CG2862 gene product from transcript CG2862-RA	0.017
Kap-alpha1	karyopherin alpha1	0.017
sty	sprouty	0.016
CG14482	CG14482 gene product from transcript CG14482-RA	0.016
CG9099	CG9099 gene product from transcript CG9099-RA	0.015
mus209	mutagen-sensitive 209	0.015
CG3560	CG3560 gene product from transcript CG3560-RA	0.014
fz	frizzled	0.014
sax	saxophone	0.014
CG7504	CG7504 gene product from transcript CG7504-RC	0.014
CG18177	CG18177 gene product from transcript CG18177-RA	0.014
dgt2	dim gamma-tubulin 2	0.014
CG9172	CG9172 gene product from transcript CG9172-RA	0.013
CG9740	CG9740 gene product from transcript CG9740-RA	0.013
hh	hedgehog	0.013
CG12129	CG12129 gene product from transcript CG12129-RA	0.013
Egfr	Epidermal growth factor receptor	0.013
CG7519	CG7519 gene product from transcript CG7519-RA	0.013
l(2)35Di	lethal (2) 35Di	0.013
MED18	Mediator complex subunit 18	0.012
smo	smoothened	0.012
CG7741	CG7741 gene product from transcript CG7741-RA	0.012
CG11107	CG11107 gene product from transcript CG11107-RA	0.012
Chro	Chromator	0.012
jigr1	jing interacting gene regulatory 1	0.011
pum	pumilio	0.011
Sir2	CG5216 gene product from transcript CG5216-RA	0.011
mod(mdg4)	modifier of mdg4	0.011
CoVa	Cytochrome c oxidase subunit Va	0.011
CG14646	CG14646 gene product from transcript CG14646-RA	0.011
CG2316	CG2316 gene product from transcript CG2316-RD	0.011
l(3)neo18	lethal (3) neo18	0.011
CG8436	CG8436 gene product from transcript CG8436-RA	0.011
CG4119	CG4119 gene product from transcript CG4119-RA	0.010
H	Hairless	0.010
CG7181	CG7181 gene product from transcript CG7181-RA	0.010
MED22	Mediator complex subunit 22	0.010
Su(z)12	CG8013 gene product from transcript CG8013-RA	0.010
crm	cramped	0.010
CG10664	CG10664 gene product from transcript CG10664-RB	0.010
sced	scrambled	0.010

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Homo sapiens

Name	Description	Probability
HSPA1B	heat shock 70kDa protein 1B	0.994
HSPA1A	heat shock 70kDa protein 1A	0.838
BAG3	BCL2-associated athanogene 3	0.716
MCTS1	malignant T cell amplified sequence 1	0.664
BAG1	BCL2-associated athanogene	0.299
UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)	0.156
ETF1	eukaryotic translation termination factor 1	0.128
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.111
DENR	density-regulated protein	0.088
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.076
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.067
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.064
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.060
HSPH1	heat shock 105kDa/110kDa protein 1	0.052
RBM17	RNA binding motif protein 17	0.052
ISY1	ISY1 splicing factor homolog (S. cerevisiae)	0.046
MRPS27	mitochondrial ribosomal protein S27	0.033
USP9Y	ubiquitin specific peptidase 9, Y-linked	0.032
HSPB1	heat shock 27kDa protein 1	0.030
SUGP1	SURP and G patch domain containing 1	0.030
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.028
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.021
CHERP	calcium homeostasis endoplasmic reticulum protein	0.021
MPRIP	myosin phosphatase Rho interacting protein	0.019
AMD1	adenosylmethionine decarboxylase 1	0.019
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.018
QARS	glutaminyl-tRNA synthetase	0.017
NKAP	NFKB activating protein	0.016
SAP30BP	SAP30 binding protein	0.015
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.014
HSPB8	heat shock 22kDa protein 8	0.014
MARK3	MAP/microtubule affinity-regulating kinase 3	0.014
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.014
PABPC1	poly(A) binding protein, cytoplasmic 1	0.014
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.013
ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.013
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.012
TSC2	tuberous sclerosis 2	0.012
XRN2	5'-3' exoribonuclease 2	0.012
PPP5C	protein phosphatase 5, catalytic subunit	0.011

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Mus musculus

Name	Description	Probability
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.983
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.926
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.546
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.527
Stip1	stress-induced phosphoprotein 1	0.434
Syncrip	synaptotagmin binding, cytoplasmic RNA interacting protein	0.415
Clstn1	calsyntenin 1	0.398
Cct6a	chaperonin containing Tcp1, subunit 6a (zeta)	0.354
Kif5c	kinesin family member 5C	0.276
Bzw1	basic leucine zipper and W2 domains 1	0.249
Otud6b	OTU domain containing 6B	0.239
Ddx3x	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked	0.229
Eif3j	eukaryotic translation initiation factor 3, subunit J	0.207
Abce1	ATP-binding cassette, sub-family E (OABP), member 1	0.188
Esf1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	0.181
Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.181
Spag9	sperm associated antigen 9	0.168
Ncoa2	nuclear receptor coactivator 2	0.161
Hnrnpf	heterogeneous nuclear ribonucleoprotein F	0.158
Eif3a	eukaryotic translation initiation factor 3, subunit A	0.151
Kpnb1	karyopherin (importin) beta 1	0.148
Hsph1	heat shock 105kDa/110kDa protein 1	0.147
Eif5	eukaryotic translation initiation factor 5	0.140
Tcea1	transcription elongation factor A (SII) 1	0.139
Ddx21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	0.132
Klc1	kinesin light chain 1	0.122
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.105
Caprin1	cell cycle associated protein 1	0.105
Napb	N-ethylmaleimide sensitive fusion protein attachment protein beta	0.097
Lamp3	lysosomal-associated membrane protein 3	0.092
Kpna1	karyopherin (importin) alpha 1	0.091
Canx	calnexin	0.087
Lrrc59	leucine rich repeat containing 59	0.085
Hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	0.077
Mark4	MAP/microtubule affinity-regulating kinase 4	0.074
Uty	ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome	0.073
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.071
Iars	isoleucine-tRNA synthetase	0.067
Ipo7	importin 7	0.067
Smarca5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0.067
Hap1	huntingtin-associated protein 1	0.064
Eif4g2	eukaryotic translation initiation factor 4, gamma 2	0.061
Eif2s3x	eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked	0.058
Kif5b	kinesin family member 5B	0.057
Gtpbp4	GTP binding protein 4	0.057
Dlg4	discs, large homolog 4 (Drosophila)	0.056
Snap25	synaptosomal-associated protein 25	0.055
Mapk8	mitogen-activated protein kinase 8	0.053
Impad1	inositol monophosphatase domain containing 1	0.051
Eif5b	eukaryotic translation initiation factor 5B	0.050
Hspd1	heat shock protein 1 (chaperonin)	0.050
Pde12	phosphodiesterase 12	0.049
Naa15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	0.046
Nars	asparaginyl-tRNA synthetase	0.045
Dtnb	dystrobrevin, beta	0.045
Eprs	glutamyl-prolyl-tRNA synthetase	0.043
Rsl1d1	ribosomal L1 domain containing 1	0.042
Kpna3	karyopherin (importin) alpha 3	0.041
Sult4a1	sulfotransferase family 4A, member 1	0.041
Srsf1	serine/arginine-rich splicing factor 1	0.041
Srsf2	serine/arginine-rich splicing factor 2	0.040
Mat2a	methionine adenosyltransferase II, alpha	0.040
Kdm5d	lysine (K)-specific demethylase 5D	0.039
Eif2s3y	eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked	0.038
Larp4	La ribonucleoprotein domain family, member 4	0.038
Etf1	eukaryotic translation termination factor 1	0.037
Tars	threonyl-tRNA synthetase	0.037
Rpgrip1l	Rpgrip1-like	0.037
Homer1	homer homolog 1 (Drosophila)	0.037
Gm2223	predicted pseudogene 2223	0.034
Arcn1	archain 1	0.034
Ckb	creatine kinase, brain	0.033
Utp6	UTP6, small subunit (SSU) processome component, homolog (yeast)	0.033
Hccs	holocytochrome c synthetase	0.033
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.032
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.032
Ncl	nucleolin	0.032
Hnrnpu	heterogeneous nuclear ribonucleoprotein U	0.029
Dnaja1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.028
Hspa4	heat shock protein 4	0.027
Hspa5	heat shock protein 5	0.027
Nsf	N-ethylmaleimide sensitive fusion protein	0.026
Klc2	kinesin light chain 2	0.026
Kif3b	kinesin family member 3B	0.026
2410042D21Rik	RIKEN cDNA 2410042D21 gene	0.025
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.025
Hgs	HGF-regulated tyrosine kinase substrate	0.024
Sdccag3	serologically defined colon cancer antigen 3	0.024
Srsf10	serine/arginine-rich splicing factor 10	0.023
Rsph1	radial spoke head 1 homolog (Chlamydomonas)	0.023
Rusc1	RUN and SH3 domain containing 1	0.022
Nefm	neurofilament, medium polypeptide	0.022
Dctn1	dynactin 1	0.022
Ifrd1	interferon-related developmental regulator 1	0.022
Morf4l2	mortality factor 4 like 2	0.021
Pacsin1	protein kinase C and casein kinase substrate in neurons 1	0.021
Ubqln1	ubiquilin 1	0.021
Usp38	ubiquitin specific peptidase 38	0.021
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.021
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.021

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Saccharomyces cerevisiae

Name	Description	Probability
SSA4	Ssa4p	0.166
STI1	Sti1p	0.100
SSA3	Ssa3p	0.059
BTN2	Btn2p	0.059
SSA1	Ssa1p	0.050
SPP382	Spp382p	0.047
SWC7	Swc7p	0.037
LIF1	Lif1p	0.035
NOP10	Nop10p	0.034
NTR2	Ntr2p	0.031
PRP45	Prp45p	0.030
SQS1	Sqs1p	0.026
HSP78	Hsp78p	0.025
KAR2	Kar2p	0.022
PRP8	Prp8p	0.022
YDJ1	Ydj1p	0.022
FAS2	Fas2p	0.021
PRP16	Prp16p	0.021
RPS5	Rps5p	0.021
SBH1	Sbh1p	0.019
SIS1	Sis1p	0.019
SSA2	Ssa2p	0.019
YLR264C-A	hypothetical protein	0.017
SRD1	Srd1p	0.016
YHB1	Yhb1p	0.015
CTR9	Ctr9p	0.015
YBL010C	hypothetical protein	0.015
YER039C-A	hypothetical protein	0.015
GYL1	Gyl1p	0.014
NMT1	Nmt1p	0.014
ARP10	Arp10p	0.014
HSP26	Hsp26p	0.014
SIL1	Sil1p	0.014
GUT2	Gut2p	0.014
YOL098C	hypothetical protein	0.014
UBP1	Ubp1p	0.014
YOL038C-A	hypothetical protein	0.014
LEU2	Leu2p	0.014
FUN12	Fun12p	0.013
YLR162W	hypothetical protein	0.013
ENO1	Eno1p	0.013
YLR042C	hypothetical protein	0.013
CWC2	Cwc2p	0.013
HXT3	Hxt3p	0.012
SEC62	Sec62p	0.012
URA3	Ura3p	0.012
YGL036W	hypothetical protein	0.012
ICS2	Ics2p	0.012
YGR054W	hypothetical protein	0.012
SSE1	Sse1p	0.012
SEN54	Sen54p	0.012
ARG8	Arg8p	0.012
YIR035C	hypothetical protein	0.012
PXA1	Pxa1p	0.012
YAR068W	hypothetical protein	0.012
PCL10	Pcl10p	0.012
CLF1	Clf1p	0.011
ALT2	Alt2p	0.011
ARO10	Aro10p	0.011
ATP6	Atp6p	0.011
TIF35	Tif35p	0.011
HO	Hop	0.011
AGC1	Agc1p	0.011
SRX1	Srx1p	0.011
BSC1	Bsc1p	0.011
CUP1-1	Cup1-1p	0.011
MER1	Mer1p	0.011
YBR085C-A	hypothetical protein	0.011
MDJ1	Mdj1p	0.011
YBR013C	hypothetical protein	0.011
ARO9	Aro9p	0.011
CBP1	Cbp1p	0.011
YLR126C	hypothetical protein	0.011
HPF1	Hpf1p	0.010
YPR157W	hypothetical protein	0.010
TIP1	Tip1p	0.010