The network for 'cellular response to peptide' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to peptide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.

NameDescriptionProbabilityFunc Analog Organism
Akr1c18aldo-keto reductase family 1, member C180.717
Ptgs2prostaglandin-endoperoxide synthase 20.706
Sult1a1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 10.695
Akr1c14aldo-keto reductase family 1, member C140.579
Egfrepidermal growth factor receptor0.578
Flt1FMS-related tyrosine kinase 10.577
Col1a1collagen, type I, alpha 10.524
Prlrprolactin receptor0.497
Mgst2microsomal glutathione S-transferase 20.493
Ptp4a1protein tyrosine phosphatase type IVA, member 10.453
Ephx1epoxide hydrolase 1, microsomal0.451
Nr4a3nuclear receptor subfamily 4, group A, member 30.446
Calm1calmodulin 10.444
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.434
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.427
Hprt1hypoxanthine phosphoribosyltransferase 10.415
Tgfbr2transforming growth factor, beta receptor II0.401
Il9rinterleukin 9 receptor0.396
Olr37olfactory receptor 370.372
Il5interleukin 50.361
Dusp6dual specificity phosphatase 60.360
Pgam1phosphoglycerate mutase 1 (brain)0.355
Sult2a1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.351
Col1a2collagen, type I, alpha 20.343
Gstm2glutathione S-transferase mu 20.342
Agtr1aangiotensin II receptor, type 1a0.337
Smad2SMAD family member 20.334
Jak2Janus kinase 20.332
Pfkfb46-phosphofructo-2-kinase/fructose-2,6-biphosphatase 40.331
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.327
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.321
Metmet proto-oncogene0.318
Myo1bmyosin Ib0.312
Il6interleukin 60.307
Mgst1microsomal glutathione S-transferase 10.306
Irs1insulin receptor substrate 10.304
Aldh6a1aldehyde dehydrogenase 6 family, member A10.303
Col3a1collagen, type III, alpha 10.303
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.302
Bcl2l1Bcl2-like 10.301
Hmgcr3-hydroxy-3-methylglutaryl-Coenzyme A reductase0.297
Haao3-hydroxyanthranilate 3,4-dioxygenase0.295
Cd14CD14 molecule0.294
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.293
Col15a1collagen, type XV, alpha 10.287
Plauplasminogen activator, urokinase0.282
Socs3suppressor of cytokine signaling 30.281
Cyp2c11cytochrome P450, subfamily 2, polypeptide 110.281
Stat5bsignal transducer and activator of transcription 5B0.277
Cps1carbamoyl-phosphate synthetase 10.273
Grb2growth factor receptor bound protein 20.269
Bdkrb1bradykinin receptor B10.267
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.267
Abp1amiloride binding protein 1 (amine oxidase, copper-containing)0.265
Nr1h4nuclear receptor subfamily 1, group H, member 40.265
Adaradenosine deaminase, RNA-specific0.261
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.258
RT1-M5RT1 class Ib, locus M50.256
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.255
Cdc42cell division cycle 42 (GTP binding protein)0.254
Ugt2b37UDP-glucuronosyltransferase 2 family, member 370.253
Ces1fcarboxylesterase 1F0.253
CnbpCCHC-type zinc finger, nucleic acid binding protein0.253
Slco2b1solute carrier organic anion transporter family, member 2b10.249
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.249
Col5a2collagen, type V, alpha 20.235
Cd80Cd80 molecule0.234
Akt2v-akt murine thymoma viral oncogene homolog 20.232
Igtpinterferon gamma induced GTPase0.230
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.227
Crygfcrystallin, gamma F0.226
Cdk4cyclin-dependent kinase 40.219
Il8rainterleukin 8 receptor, alpha0.215
Stc1stanniocalcin 10.210
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 80.209
Col10a1collagen, type X, alpha 10.206
Pth1rparathyroid hormone 1 receptor0.206
Nfianuclear factor I/A0.203
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.202
Lig3ligase III, DNA, ATP-dependent0.202
Cybbcytochrome b-245, beta polypeptide0.200
Sfrp4secreted frizzled-related protein 40.198
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.194
Gstm1glutathione S-transferase mu 10.193
Cst8cystatin 8 (cystatin-related epididymal specific)0.193
Slc8a1solute carrier family 8 (sodium/calcium exchanger), member 10.193
Ppp1r2protein phosphatase 1, regulatory (inhibitor) subunit 20.191
Rararetinoic acid receptor, alpha0.191
Svs3aseminal vesicle secretory protein 3A0.189
Postnperiostin, osteoblast specific factor0.188
Akr7a3aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)0.187
Pik3r1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.185
P2ry2purinergic receptor P2Y, G-protein coupled, 20.183
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.182
Otcornithine carbamoyltransferase0.181
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
nfm-1Protein NFM-10.018
pry-1Protein PRY-10.017
obr-3Protein OBR-30.015
K02A6.2Protein K02A6.20.013
ptr-11Protein PTR-110.013
hlh-14Protein HLH-140.013
T19D12.6Protein T19D12.60.012
ccch-1Protein CCCH-10.012
oac-46Protein OAC-460.011
CELE_Y47G6A.13Protein Y47G6A.130.011
plc-3Protein PLC-30.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ptpraprotein tyrosine phosphatase, receptor type, A0.105
igf1insulin-like growth factor 10.033
adipoqladiponectin, C1Q and collagen domain containing, like0.032
socs3asuppressor of cytokine signaling 3a0.029
sec24cSEC24 family, member C (S. cerevisiae)0.026
alcamaactivated leukocyte cell adhesion molecule a0.025
kif5bbkinesin family member 5B, b0.020
epas1bendothelial PAS domain protein 1b0.019
ptk2.1protein tyrosine kinase 2a0.017
fabp11afatty acid binding protein 11a0.017
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.016
fmr1fragile X mental retardation 10.015
csadcysteine sulfinic acid decarboxylase0.015
mbpmyelin basic protein0.015
prox1prospero-related homeobox gene 10.014
sh3gl1bSH3-domain GRB2-like 1b0.014
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.014
tm4sf4transmembrane 4 L six family member 40.013
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.013
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.013
has2hyaluronan synthase 20.012
jak1Janus kinase 10.012
odc1ornithine decarboxylase 10.011
zbtb4zinc finger and BTB domain containing 40.010
rtf1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.966
InRInsulin-like receptor0.804
LnkCG17367 gene product from transcript CG17367-RC0.745
IndyI'm not dead yet0.544
S6kRPS6-p70-protein kinase0.490
Ilp5Insulin-like peptide 50.386
picoCG11940 gene product from transcript CG11940-RA0.310
Ras85DRas oncogene at 85D0.287
CycDCyclin D0.285
Ilp2Insulin-like peptide 20.211
MntCG13316 gene product from transcript CG13316-RD0.209
CG13310CG13310 gene product from transcript CG13310-RA0.208
Ilp6Insulin-like peptide 60.206
Rac1CG2248 gene product from transcript CG2248-RA0.180
Ilp3Insulin-like peptide 30.163
Akt1CG4006 gene product from transcript CG4006-RA0.158
Gyc76CGuanylyl cyclase at 76C0.157
Cdc42CG12530 gene product from transcript CG12530-RA0.157
ThorCG8846 gene product from transcript CG8846-RA0.154
sNPF-Rshort neuropeptide F receptor0.148
Octbeta2RCG33976 gene product from transcript CG33976-RA0.139
rictorrapamycin-insensitive companion of Tor0.135
Pk61CProtein kinase 61C0.118
CG15828CG15828 gene product from transcript CG15828-RC0.111
RagACG11968 gene product from transcript CG11968-RA0.111
CycGCyclin G0.110
RanBPMRan-binding protein M0.094
CG13253CG13253 gene product from transcript CG13253-RB0.089
MadMothers against dpp0.086
sNPFshort neuropeptide F precursor0.074
foxoforkhead box, sub-group O0.070
CG11486CG11486 gene product from transcript CG11486-RG0.068
CG3837CG3837 gene product from transcript CG3837-RA0.065
PezCG9493 gene product from transcript CG9493-RA0.063
Lsd-2Lipid storage droplet-20.062
CG1607CG1607 gene product from transcript CG1607-RA0.059
RN-tretre oncogene-related protein0.056
TbhTyramine beta hydroxylase0.055
Su(dx)Suppressor of deltex0.054
FhosCG42610 gene product from transcript CG42610-RC0.053
Pdp1PAR-domain protein 10.053
WnkCG7177 gene product from transcript CG7177-RA0.051
skpACG16983 gene product from transcript CG16983-RD0.051
Atg1Autophagy-specific gene 10.047
trptransient receptor potential0.046
Bre1CG10542 gene product from transcript CG10542-RA0.045
Nf1Neurofibromin 10.045
slikSterile20-like kinase0.045
RhebCG1081 gene product from transcript CG1081-RA0.044
Gycalpha99BGuanylyl cyclase alpha-subunit at 99B0.044
phlpole hole0.043
CG11055CG11055 gene product from transcript CG11055-RB0.043
BRWD3CG31132 gene product from transcript CG31132-RA0.042
BHDBirt-Hogg-Dube homolog0.041
CdsACDP diglyceride synthetase0.040
Rab7Rab-protein 70.040
McrMacroglobulin complement-related0.039
PdfPigment-dispersing factor0.039
TorTarget of rapamycin0.039
CG14869CG14869 gene product from transcript CG14869-RB0.038
LamCLamin C0.038
fkhfork head0.038
IdeInsulin degrading metalloproteinase0.036
ird1immune response deficient 10.036
rolsrolling pebbles0.035
fl(2)dfemale lethal d0.035
HphHIF prolyl hydroxylase0.034
Hr96Hormone receptor-like in 960.034
RdlResistant to dieldrin0.034
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PTPN1protein tyrosine phosphatase, non-receptor type 11.000
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)1.000
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.999
CREBBPCREB binding protein0.997
GRB2growth factor receptor-bound protein 20.996
EGFRepidermal growth factor receptor0.996
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.996
BCAR1breast cancer anti-estrogen resistance 10.994
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.990
PTK2PTK2 protein tyrosine kinase 20.990
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.978
ESR1estrogen receptor 10.975
PTPN11protein tyrosine phosphatase, non-receptor type 110.969
INSRinsulin receptor0.959
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.953
SHC1SHC (Src homology 2 domain containing) transforming protein 10.948
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.904
GRB10growth factor receptor-bound protein 100.903
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.899
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.868
EP300E1A binding protein p3000.864
JAK2Janus kinase 20.844
RXRAretinoid X receptor, alpha0.825
NCOA1nuclear receptor coactivator 10.815
IRS2insulin receptor substrate 20.803
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.792
NCK1NCK adaptor protein 10.655
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.620
MAP3K11mitogen-activated protein kinase kinase kinase 110.617
RASA1RAS p21 protein activator (GTPase activating protein) 10.614
CAV1caveolin 1, caveolae protein, 22kDa0.614
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.587
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.564
NCK2NCK adaptor protein 20.556
NCF1neutrophil cytosolic factor 10.555
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.553
FHL2four and a half LIM domains 20.510
IGF1Rinsulin-like growth factor 1 receptor0.506
TSC2tuberous sclerosis 20.498
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.480
TOB1transducer of ERBB2, 10.469
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.451
CUL1cullin 10.426
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.409
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.395
FYNFYN oncogene related to SRC, FGR, YES0.378
SOCS1suppressor of cytokine signaling 10.360
PLCG1phospholipase C, gamma 10.360
IRS1insulin receptor substrate 10.352
VEGFAvascular endothelial growth factor A0.349
SP1Sp1 transcription factor0.333
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.322
GH1growth hormone 10.313
IFNAR1interferon (alpha, beta and omega) receptor 10.301
FBXW11F-box and WD repeat domain containing 110.295
EPAS1endothelial PAS domain protein 10.287
IFNAR2interferon (alpha, beta and omega) receptor 20.285
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.281
GSK3Bglycogen synthase kinase 3 beta0.274
GHRgrowth hormone receptor0.260
EPORerythropoietin receptor0.260
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.260
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.256
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.255
LATlinker for activation of T cells0.246
SOCS3suppressor of cytokine signaling 30.245
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.242
NCOA2nuclear receptor coactivator 20.237
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.232
BCL3B-cell CLL/lymphoma 30.230
SH3RF1SH3 domain containing ring finger 10.224
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.219
PDPK13-phosphoinositide dependent protein kinase-10.213
MTORmechanistic target of rapamycin (serine/threonine kinase)0.210
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.199
NCOR2nuclear receptor corepressor 20.192
SH2B1SH2B adaptor protein 10.182
PRKCAprotein kinase C, alpha0.177
SHC2SHC (Src homology 2 domain containing) transforming protein 20.167
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.166
PTK2BPTK2B protein tyrosine kinase 2 beta0.156
ARandrogen receptor0.153
SKP1S-phase kinase-associated protein 10.152
VAV1vav 1 guanine nucleotide exchange factor0.145
CREB1cAMP responsive element binding protein 10.142
IL4Rinterleukin 4 receptor0.136
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.135
LIMS1LIM and senescent cell antigen-like domains 10.135
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.133
MEF2Cmyocyte enhancer factor 2C0.132
WEE1WEE1 homolog (S. pombe)0.131
FYBFYN binding protein0.129
MAPTmicrotubule-associated protein tau0.124
CAPNS1calpain, small subunit 10.123
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.123
POU5F1POU class 5 homeobox 10.118
SIRT1sirtuin 10.117
RICTORRPTOR independent companion of MTOR, complex 20.116
SOS1son of sevenless homolog 1 (Drosophila)0.115
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Leprleptin receptor1.000
Insrinsulin receptor0.999
Stat3signal transducer and activator of transcription 30.999
Ppargperoxisome proliferator activated receptor gamma0.997
Cav1caveolin 1, caveolae protein0.987
Cdkn1bcyclin-dependent kinase inhibitor 1B0.985
Trp53transformation related protein 530.980
Nos3nitric oxide synthase 3, endothelial cell0.977
Ctnnb1catenin (cadherin associated protein), beta 10.960
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.954
Bglapbone gamma carboxyglutamate protein0.952
Jak2Janus kinase 20.947
Tgfb1transforming growth factor, beta 10.945
Vegfavascular endothelial growth factor A0.940
Egfrepidermal growth factor receptor0.930
CblCasitas B-lineage lymphoma0.929
Csf1colony stimulating factor 1 (macrophage)0.929
Stat5asignal transducer and activator of transcription 5A0.925
Nos1nitric oxide synthase 1, neuronal0.919
Ghrgrowth hormone receptor0.914
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.888
Apoeapolipoprotein E0.874
Nr3c1nuclear receptor subfamily 3, group C, member 10.865
Grb2growth factor receptor bound protein 20.845
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.834
FynFyn proto-oncogene0.831
Apcadenomatosis polyposis coli0.829
Stat5bsignal transducer and activator of transcription 5B0.823
Ptpn11protein tyrosine phosphatase, non-receptor type 110.821
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.806
Irs2insulin receptor substrate 20.801
Dusp1dual specificity phosphatase 10.795
Ldlrlow density lipoprotein receptor0.786
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.782
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.779
Lipelipase, hormone sensitive0.770
Ins2insulin II0.766
SrcRous sarcoma oncogene0.761
Ptgs2prostaglandin-endoperoxide synthase 20.742
FosFBJ osteosarcoma oncogene0.732
Lyz2lysozyme 20.709
Il6stinterleukin 6 signal transducer0.705
Sim1single-minded homolog 1 (Drosophila)0.704
Tnftumor necrosis factor0.697
Esr1estrogen receptor 1 (alpha)0.692
Mup19major urinary protein 190.690
Il1r1interleukin 1 receptor, type I0.682
Pnpla2patatin-like phospholipase domain containing 20.666
Otporthopedia homolog (Drosophila)0.665
Lhcgrluteinizing hormone/choriogonadotropin receptor0.663
Ptk2PTK2 protein tyrosine kinase 20.654
Slc12a1solute carrier family 12, member 10.645
Prlrprolactin receptor0.632
Inpp5dinositol polyphosphate-5-phosphatase D0.628
JunJun oncogene0.621
Fshrfollicle stimulating hormone receptor0.607
C1qacomplement component 1, q subcomponent, alpha polypeptide0.583
Lrp1low density lipoprotein receptor-related protein 10.581
Grb10growth factor receptor bound protein 100.571
Nr5a1nuclear receptor subfamily 5, group A, member 10.569
Smad3MAD homolog 3 (Drosophila)0.563
Nr1h4nuclear receptor subfamily 1, group H, member 40.554
LOC100048884novel member of the major urinary protein (Mup) gene family0.544
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.538
Vhlvon Hippel-Lindau tumor suppressor0.536
Chst8carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 80.521
Igbp1immunoglobulin (CD79A) binding protein 10.502
Ptenphosphatase and tensin homolog0.499
Tsc1tuberous sclerosis 10.478
Cd44CD44 antigen0.472
Shc1src homology 2 domain-containing transforming protein C10.467
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.463
Arid1bAT rich interactive domain 1B (SWI-like)0.461
Rhobras homolog gene family, member B0.452
Dok1docking protein 10.446
Ubcubiquitin C0.442
Mup5major urinary protein 50.433
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.433
Plcg1phospholipase C, gamma 10.425
Irs1insulin receptor substrate 10.421
Plin1perilipin 10.419
Cishcytokine inducible SH2-containing protein0.414
Socs3suppressor of cytokine signaling 30.398
FasFas (TNF receptor superfamily member 6)0.376
Bcar1breast cancer anti-estrogen resistance 10.374
C1qccomplement component 1, q subcomponent, C chain0.362
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.362
Arandrogen receptor0.345
Gnao1guanine nucleotide binding protein, alpha O0.344
Clockcircadian locomotor output cycles kaput0.341
Tlr4toll-like receptor 40.337
Atf4activating transcription factor 40.334
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.334
Ren1renin 1 structural0.332
TyrobpTYRO protein tyrosine kinase binding protein0.327
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism