The network for 'positive regulation of cell communication' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cell communication

Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

NameDescriptionProbabilityFunc Analog Organism
Ptafrplatelet-activating factor receptor0.787
Agtr1aangiotensin II receptor, type 1a0.745
Nrxn1neurexin 10.723
Ctsjcathepsin J0.696
Slco2b1solute carrier organic anion transporter family, member 2b10.679
Fgfr2fibroblast growth factor receptor 20.678
Nfascneurofascin0.672
Kcnj16potassium inwardly-rectifying channel, subfamily J, member 160.671
Oprm1opioid receptor, mu 10.666
Prrx1paired related homeobox 10.655
Grin2dglutamate receptor, ionotropic, N-methyl D-aspartate 2D0.645
Bcl2B-cell CLL/lymphoma 20.638
GperG protein-coupled estrogen receptor 10.630
Pnlippancreatic lipase0.629
Olr1654olfactory receptor 16540.625
Vegp2von Ebners gland protein 20.581
Gng7guanine nucleotide binding protein (G protein), gamma 70.580
Igfbp5insulin-like growth factor binding protein 50.576
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.573
Grm7glutamate receptor, metabotropic 70.561
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.557
Gja6gap junction protein, alpha 60.548
Map2microtubule-associated protein 20.538
Tgfbr2transforming growth factor, beta receptor II0.537
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.532
Nrg1neuregulin 10.522
Cd14CD14 molecule0.521
Mapk9mitogen-activated protein kinase 90.520
Pparaperoxisome proliferator activated receptor alpha0.520
Apol3apolipoprotein L, 30.504
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.503
Adora2aadenosine A2a receptor0.503
Bdkrb2bradykinin receptor B20.496
Itpr2inositol 1,4,5-triphosphate receptor, type 20.495
Leprleptin receptor0.493
Scn9asodium channel, voltage-gated, type IX, alpha0.491
Gria1glutamate receptor, ionotropic, AMPA 10.484
Csf1colony stimulating factor 1 (macrophage)0.467
Cd44Cd44 molecule0.466
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.459
Cntn2contactin 2 (axonal)0.459
Il4interleukin 40.459
Mogmyelin oligodendrocyte glycoprotein0.458
Drd3dopamine receptor D30.457
Notch3Notch homolog 3 (Drosophila)0.451
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.450
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.442
S100a8S100 calcium binding protein A80.441
Dlg1discs, large homolog 1 (Drosophila)0.439
Prkcaprotein kinase C, alpha0.435
Cd4Cd4 molecule0.434
Cdh22cadherin 220.433
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.433
Lhx5LIM homeobox 50.430
Trhrthyrotropin releasing hormone receptor0.428
Ptgfrprostaglandin F receptor0.425
Edn1endothelin 10.425
Cd247Cd247 molecule0.424
Adarb2adenosine deaminase, RNA-specific, B20.420
Lifrleukemia inhibitory factor receptor alpha0.413
Utrnutrophin0.409
Mamdc4MAM domain containing 40.408
Dlg4discs, large homolog 4 (Drosophila)0.406
Nr5a2nuclear receptor subfamily 5, group A, member 20.406
Sstr1somatostatin receptor 10.406
Stxbp2syntaxin binding protein 20.404
Gcnt3glucosaminyl (N-acetyl) transferase 3, mucin type0.402
Hoxa2homeo box A20.402
Cplx1complexin 10.402
Egfrepidermal growth factor receptor0.401
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.400
RT1-BaRT1 class II, locus Ba0.392
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.391
Cnga2cyclic nucleotide gated channel alpha 20.390
Unc5bunc-5 homolog B (C. elegans)0.389
Hpcal4hippocalcin-like 40.389
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 80.384
Bcanbrevican0.383
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.382
Mbpmyelin basic protein0.376
Il12binterleukin 12B0.375
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.374
Ghsrgrowth hormone secretagogue receptor0.373
Jak2Janus kinase 20.372
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.368
Tnftumor necrosis factor (TNF superfamily, member 2)0.367
Shox2short stature homeobox 20.367
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.366
Prkchprotein kinase C, eta0.365
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.364
Ralgdsral guanine nucleotide dissociation stimulator0.363
Efnb1ephrin B10.363
Cdk4cyclin-dependent kinase 40.363
Usf2upstream transcription factor 2, c-fos interacting0.363
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.362
Trhthyrotropin releasing hormone0.362
Gja5gap junction protein, alpha 50.359
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.358
Serpini2serine (or cysteine) peptidase inhibitor, clade I, member 20.358
Fgf1fibroblast growth factor 10.354
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
unc-9Protein UNC-90.868
egl-18Protein EGL-180.825
mpk-1Protein MPK-10.691
ten-1Protein TEN-10.655
lmn-1Protein LMN-10.624
let-60Protein LET-600.575
soc-2Protein SOC-20.478
bar-1Protein BAR-10.433
itr-1Protein ITR-10.427
egl-15Protein EGL-150.418
hmg-1.2Protein HMG-1.20.389
zyg-9Protein ZYG-90.358
gpb-1Protein GPB-10.344
ist-1Protein IST-10.342
pha-4Protein PHA-40.341
hnd-1Protein HND-10.332
pkg-1Protein PKG-10.325
mrt-2Protein MRT-20.307
daf-11Protein DAF-110.270
sem-5Protein SEM-50.252
msp-36Protein MSP-360.239
msp-55Protein MSP-550.232
sma-6Protein SMA-60.221
msp-76Protein MSP-760.220
msp-78Protein MSP-780.220
sax-3Protein SAX-30.218
unc-43Protein UNC-430.218
svh-2Protein SVH-20.217
arf-3Protein ARF-30.216
hda-3Protein HDA-30.211
unc-10Protein UNC-100.210
mat-3Protein MAT-30.205
pal-1Protein PAL-10.204
apr-1Protein APR-10.201
abl-1Protein ABL-10.198
mep-1Protein MEP-10.197
sym-4Protein SYM-40.196
msp-40Protein MSP-400.194
CELE_F52C6.12Protein F52C6.120.190
let-756Protein LET-7560.188
daf-12Protein DAF-120.187
tag-343Protein TAG-3430.186
msp-77Protein MSP-770.181
sgt-1Protein SGT-10.178
gei-18Protein GEI-180.176
C11E4.6Protein C11E4.60.171
saeg-1Protein SAEG-10.169
gei-17Protein GEI-170.168
cyp-35A2Protein CYP-35A20.167
T23F4.2Protein T23F4.20.164
toe-4Protein TOE-40.164
rig-6Protein RIG-60.158
sur-2Protein SUR-20.158
eor-1Protein EOR-10.157
jnk-1Protein JNK-10.155
nhr-34Protein NHR-340.150
H06I04.1Protein H06I04.10.150
plc-1Protein PLC-10.148
swan-2Protein SWAN-20.148
inx-3Protein INX-30.148
osm-3Protein OSM-30.148
pxf-1Protein PXF-10.144
pop-1Protein POP-10.144
msp-50Protein MSP-500.142
msp-33Protein MSP-330.138
unc-82Protein UNC-820.137
msp-59Protein MSP-590.137
sma-10Protein SMA-100.136
vab-3Protein VAB-30.134
lag-1Protein LAG-10.134
sup-12Protein SUP-120.133
exc-7Protein EXC-70.131
csn-5Protein CSN-50.128
lsy-22Protein LSY-220.125
imb-2Protein IMB-20.125
csnk-1Protein CSNK-10.124
spc-1Protein SPC-10.124
daf-4Protein DAF-40.123
hlh-2Protein HLH-20.121
msp-19Protein MSP-190.119
pdfr-1Protein PDFR-10.118
wsp-1Protein WSP-10.117
sem-4Protein SEM-40.117
chd-7Protein CHD-70.116
dhfr-1Protein DHFR-10.115
ceh-44Protein CEH-440.115
alh-3Protein ALH-30.115
msp-10Protein MSP-100.114
sma-1Protein SMA-10.114
col-110Protein COL-1100.114
msp-65Protein MSP-650.113
unc-32Protein UNC-320.113
etr-1Protein ETR-10.113
egl-30Protein EGL-300.111
Y42H9AR.4Protein Y42H9AR.40.110
unc-37Protein UNC-370.110
atat-2Protein ATAT-20.109
pry-1Protein PRY-10.107
goa-1Protein GOA-10.105
rpm-1Protein RPM-10.102
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sox32SRY-box containing gene 320.833
sulf1sulfatase 10.820
gli1GLI-Kruppel family member 10.739
pkd2polycystic kidney disease 20.713
ippkinositol 1,3,4,5,6-pentakisphosphate 2-kinase0.644
sox9aSRY-box containing gene 9a0.588
ptk2.1protein tyrosine kinase 2a0.531
plcg1phospholipase C, gamma 10.525
dkk1bdickkopf 1b0.483
fn1fibronectin 10.450
dlcdeltaC0.432
wnt4awingless-type MMTV integration site family, member 4a0.423
ihhaIndian hedgehog homolog a0.391
sox7SRY-box containing gene 70.376
nadl1.2neural adhesion molecule L1.20.369
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.355
efnb2aephrin B2a0.350
dusp6dual specificity phosphatase 60.331
rag1recombination activating gene 10.325
dharmadharma0.307
sparcsecreted acidic cysteine rich glycoprotein0.306
bmp2abone morphogenetic protein 2a0.292
gdf6agrowth differentiation factor 6a0.292
wnt2bawingless-type MMTV integration site family, member 2Ba0.283
twist3twist30.282
fgf3fibroblast growth factor 30.265
osr1odd-skipped related 1 (Drosophila)0.258
fbn2bfibrillin 2b0.246
stmn1bstathmin 1b0.242
gli2aGLI-Kruppel family member GLI2a0.239
disp1dispatched homolog 1 (Drosophila)0.237
cdh2cadherin 2, neuronal0.234
her6hairy-related 60.234
ctsl1bcathepsin L, 1 b0.231
twist1atwist1a0.230
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.230
furinafurin (paired basic amino acid cleaving enzyme) a0.228
podxlpodocalyxin-like0.222
traf4atnf receptor-associated factor 4a0.219
chdchordin0.217
frem3Fras1 related extracellular matrix 30.215
wnt2bbwingless-type MMTV integration site family, member 2Bb0.214
wnt9bwingless-type MMTV integration site family, member 9B0.213
angpt2angiopoietin 20.210
nf1aneurofibromin 1a0.209
csnk1dacasein kinase 1, delta a0.206
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.204
hmx1H6 homeo box 10.203
vcanbversican b0.202
otpaorthopedia homolog a0.200
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.196
esr1estrogen receptor 10.195
adra2aadrenergic, alpha-2A-, receptor0.185
cdh23cadherin-like 230.184
hoxd4ahomeo box D4a0.183
ift88intraflagellar transport 88 homolog0.183
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.176
bbc3BCL2 binding component 30.169
wnt3awingless-type MMTV integration site family, member 3A0.166
stab2stabilin 20.163
shhasonic hedgehog a0.159
jag1bjagged 1b0.158
mapk1mitogen-activated protein kinase 10.156
maomonoamine oxidase0.149
pycardPYD and CARD domain containing0.148
cyp1acytochrome P450, family 1, subfamily A0.148
tnfsf10ltumor necrosis factor (ligand) superfamily, member 10 like0.148
prnprs3prion protein, related sequence 30.147
inspreproinsulin0.147
scdstearoyl-CoA desaturase (delta-9-desaturase)0.145
klf4Kruppel-like factor 40.144
dip2cDIP2 disco-interacting protein 2 homolog C (Drosophila)0.143
dag1dystroglycan 10.142
acvr1lactivin A receptor, type I like0.142
cdoncell adhesion molecule-related/down-regulated by oncogenes0.142
fezf2FEZ family zinc finger 20.139
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.138
notch2notch homolog 20.136
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.135
tp53bp2tumor protein p53 binding protein, 20.134
nlgn3aneuroligin 3a0.134
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.134
runx2arunt-related transcription factor 2a0.134
gbx2gastrulation brain homeo box 20.133
nr2f2nuclear receptor subfamily 2, group F, member 20.132
bdnfbrain-derived neurotrophic factor0.130
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.129
gfra1bgdnf family receptor alpha 1b0.127
six4.3sine oculis homeobox homolog 4.30.127
otpborthopedia homolog b0.125
gpiaglucose phosphate isomerase a0.125
her1hairy-related 10.124
rhoaaras homolog gene family, member Aa0.123
trpm7transient receptor potential cation channel, subfamily M, member 70.123
hoxa2bhomeo box A2b0.122
wnt10awingless-type MMTV integration site family, member 10a0.122
gli3GLI-Kruppel family member GLI30.121
foxd3forkhead box D30.120
lama5laminin, alpha 50.120
flhfloating head0.119
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
domedomeless0.912
mbcmyoblast city0.886
Atg1Autophagy-specific gene 10.872
SmoxSmad on X0.847
Stat92ESignal-transducer and activator of transcription protein at 92E0.826
RhebCG1081 gene product from transcript CG1081-RA0.798
putpunt0.774
SNF1ASNF1A/AMP-activated protein kinase0.761
Lis-1Lissencephaly-10.753
Nrx-IVNeurexin IV0.727
phlpole hole0.724
fzfrizzled0.722
drkdownstream of receptor kinase0.685
Akt1CG4006 gene product from transcript CG4006-RA0.654
hephemipterous0.645
spasspastin0.629
CaMKIICalcium/calmodulin-dependent protein kinase II0.599
atoatonal0.594
trioCG18214 gene product from transcript CG18214-RA0.593
ttvtout-velu0.588
ykiyorkie0.580
shishibire0.579
Ras85DRas oncogene at 85D0.566
DadDaughters against dpp0.566
kaykayak0.566
bskbasket0.556
InRInsulin-like receptor0.546
p53CG33336 gene product from transcript CG33336-RB0.524
Nup153Nucleoporin 1530.518
dosdaughter of sevenless0.515
MybMyb oncogene-like0.489
sevsevenless0.489
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.472
Pi3K92ECG4141 gene product from transcript CG4141-RB0.463
neuroliginCG13772 gene product from transcript CG13772-RA0.462
panpangolin0.459
JraJun-related antigen0.444
SosSon of sevenless0.437
ShcSHC-adaptor protein0.421
PsnPresenilin0.420
rlrolled0.419
GluRIIAGlutamate receptor IIA0.412
stcksteamer duck0.411
unc-104CG8566 gene product from transcript CG8566-RB0.405
dmdiminutive0.403
Su(H)Suppressor of Hairless0.401
EcREcdysone receptor0.395
MAN1CG3167 gene product from transcript CG3167-RA0.393
pntpointed0.390
bratbrain tumor0.386
ebiCG4063 gene product from transcript CG4063-RA0.385
fz2frizzled 20.382
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.382
gbbglass bottom boat0.379
Snr1Snf5-related 10.376
Dcp-1Death caspase-10.373
foxoforkhead box, sub-group O0.364
Ada2bCG9638 gene product from transcript CG9638-RA0.361
Fmr1CG6203 gene product from transcript CG6203-RC0.350
SnooSno oncogene0.350
Bin1Bicoid interacting protein 10.348
WnkCG7177 gene product from transcript CG7177-RA0.347
dcodiscs overgrown0.344
wlswntless0.340
PliPellino0.337
TBPHCG10327 gene product from transcript CG10327-RC0.336
Aos1CG12276 gene product from transcript CG12276-RA0.332
HLHm7E(spl) region transcript m70.329
Myo31DFMyosin 31DF0.327
HLHmgammaE(spl) region transcript mgamma0.326
Sema-1aCG18405 gene product from transcript CG18405-RD0.324
Ced-12CG5336 gene product from transcript CG5336-RA0.324
Rab7Rab-protein 70.320
Nedd4CG42279 gene product from transcript CG42279-RJ0.319
UbxUltrabithorax0.317
MadMothers against dpp0.315
dysdysfusion0.310
DabDisabled0.310
CtBPC-terminal Binding Protein0.304
CG31146CG31146 gene product from transcript CG31146-RD0.303
rutrutabaga0.302
cv-ccrossveinless c0.301
TlToll0.301
CG11347CG11347 gene product from transcript CG11347-RE0.301
jebjelly belly0.297
miltmilton0.291
Rab5Rab-protein 50.288
Dap160Dynamin associated protein 1600.287
eveeven skipped0.286
fufused0.285
wgwingless0.285
Arp66BActin-related protein 66B0.285
RhoGAP92BCG4755 gene product from transcript CG4755-RA0.283
LLobe0.283
spzspatzle0.281
Tip60CG6121 gene product from transcript CG6121-RA0.281
giggigas0.279
NetBNetrin-B0.266
liclicorne0.261
NrtNeurotactin0.261
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SSK2Ssk2p0.560
ERP4Erp4p0.529
PBS2Pbs2p0.482
CLA4Cla4p0.412
PRK1Prk1p0.288
RTT106Rtt106p0.277
SLT2Slt2p0.276
CDC28Cdc28p0.195
YPT1Ypt1p0.189
NBP2Nbp2p0.188
KDX1Kdx1p0.178
MSI1Msi1p0.171
MON1Mon1p0.159
IZH4Izh4p0.158
TRA1Tra1p0.155
TPK1Tpk1p0.154
SPT16Spt16p0.151
RHO1Rho1p0.147
BMH1Bmh1p0.137
AKL1Akl1p0.136
ERP2Erp2p0.130
BDF1Bdf1p0.129
FAR1Far1p0.122
BCK2Bck2p0.122
INP52Inp52p0.120
BCY1Bcy1p0.115
PAN1Pan1p0.109
BCK1Bck1p0.108
HHT1Hht1p0.097
SLA2Sla2p0.096
RTG3Rtg3p0.093
YAK1Yak1p0.089
GAL7Gal7p0.088
BMH2Bmh2p0.087
CDC34Cdc34p0.086
HOS4Hos4p0.083
VPS64Vps64p0.079
DNM1Dnm1p0.076
GPR1Gpr1p0.076
AQR1Aqr1p0.075
ERP5Erp5p0.072
ENA5Ena5p0.071
SSK1Ssk1p0.071
SPT15Spt15p0.068
SSK22Ssk22p0.068
SET3Set3p0.068
OLE1Ole1p0.066
SHO1Sho1p0.066
UGP1Ugp1p0.064
PLC1Plc1p0.062
RTT101Rtt101p0.062
SIF2Sif2p0.061
NGR1Ngr1p0.059
HST1Hst1p0.057
SLM2Slm2p0.057
FAR11Far11p0.055
EAF1Eaf1p0.054
ATG14Atg14p0.053
RAS1Ras1p0.052
SLM4Slm4p0.052
MEH1Meh1p0.049
PPH3Pph3p0.048
LAS17Las17p0.048
STE5Ste5p0.048
MMR1Mmr1p0.047
STE23Ste23p0.047
CKA1Cka1p0.047
TSA2Tsa2p0.045
TPK2Tpk2p0.045
EAF3Eaf3p0.044
EPL1Epl1p0.044
ARP7Arp7p0.043
ROD1Rod1p0.042
ATG13Atg13p0.042
PTC6Ptc6p0.040
GPB2Gpb2p0.040
LTV1Ltv1p0.039
HIR3Hir3p0.039
MIG1Mig1p0.038
AVO1Avo1p0.038
RAS2Ras2p0.038
RHO4Rho4p0.037
AHP1Ahp1p0.037
SKI3Ski3p0.036
RIO2Rio2p0.036
STE20Ste20p0.036
DBF2Dbf2p0.036
MKK2Mkk2p0.035
ROM2Rom2p0.035
YOR1Yor1p0.035
HSV2Hsv2p0.035
ESA1Esa1p0.035
CLB3Clb3p0.032
FUS3Fus3p0.032
BOP2Bop2p0.032
ATG32Atg32p0.031
TPS1Tps1p0.031
ERP3Erp3p0.031
CPR1Cpr1p0.031
BNR1Bnr1p0.030