The network for 'negative regulation of dephosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of dephosphorylation

Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.

NameDescriptionProbabilityFunc Analog Organism
Churc1churchill domain containing 10.013
Atp5oATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.012
RGD1306917similar to RIKEN cDNA 2900010M230.012
Timm13translocase of inner mitochondrial membrane 13 homolog (yeast)0.012
Mrpl27mitochondrial ribosomal protein L270.011
Polr2jpolymerase (RNA) II (DNA directed) polypeptide J0.011
LOC301124hypothetical LOC3011240.011
Nacanascent polypeptide-associated complex alpha subunit0.010
Eif3meukaryotic translation initiation factor 3, subunit M0.010
Timm23translocase of inner mitochondrial membrane 23 homolog (yeast)0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.987
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.927
PPP1CCprotein phosphatase 1, catalytic subunit, gamma isozyme0.864
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.651
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.568
ACTBactin, beta0.508
CDK1cyclin-dependent kinase 10.485
PFN1profilin 10.338
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.311
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.296
CDK2cyclin-dependent kinase 20.233
GDAguanine deaminase0.220
PPP1R2protein phosphatase 1, regulatory (inhibitor) subunit 20.205
SETSET nuclear oncogene0.201
MAP3K3mitogen-activated protein kinase kinase kinase 30.187
PPP1R8protein phosphatase 1, regulatory (inhibitor) subunit 80.186
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.159
ACVR1Bactivin A receptor, type IB0.147
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.142
SNF8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)0.132
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.127
AFF4AF4/FMR2 family, member 40.126
BADBCL2-associated agonist of cell death0.122
TP53BP2tumor protein p53 binding protein, 20.112
BCL2L1BCL2-like 10.111
CCND3cyclin D30.096
TCTEX1D4Tctex1 domain containing 40.094
CDHR2cadherin-related family member 20.088
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.084
KLHL3kelch-like 3 (Drosophila)0.083
PTPRCprotein tyrosine phosphatase, receptor type, C0.080
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.077
CCND1cyclin D10.076
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.073
MAGEA11melanoma antigen family A, 110.069
PBKPDZ binding kinase0.066
PLXND1plexin D10.066
PRKAR2Aprotein kinase, cAMP-dependent, regulatory, type II, alpha0.065
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.065
TGFBR1transforming growth factor, beta receptor 10.063
ADAM17ADAM metallopeptidase domain 170.063
FAT1FAT tumor suppressor homolog 1 (Drosophila)0.062
LMTK2lemur tyrosine kinase 20.059
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.057
CDC25Bcell division cycle 25 homolog B (S. pombe)0.055
PPP1R10protein phosphatase 1, regulatory (inhibitor) subunit 100.052
CCNB1cyclin B10.051
PPP1R13Bprotein phosphatase 1, regulatory (inhibitor) subunit 13B0.051
C3orf15chromosome 3 open reading frame 150.050
LCKlymphocyte-specific protein tyrosine kinase0.050
MARK2MAP/microtubule affinity-regulating kinase 20.048
WWP2WW domain containing E3 ubiquitin protein ligase 20.048
PPP1R15Bprotein phosphatase 1, regulatory (inhibitor) subunit 15B0.047
RIPK3receptor-interacting serine-threonine kinase 30.047
CDK6cyclin-dependent kinase 60.046
STAU1staufen, RNA binding protein, homolog 1 (Drosophila)0.045
NOP58NOP58 ribonucleoprotein homolog (yeast)0.044
PKM2pyruvate kinase, muscle0.043
AKT1v-akt murine thymoma viral oncogene homolog 10.043
EAF1ELL associated factor 10.043
SORBS3sorbin and SH3 domain containing 30.043
NCKAP1NCK-associated protein 10.043
CHN2chimerin (chimaerin) 20.040
CDC25Ccell division cycle 25 homolog C (S. pombe)0.040
ZFYVE9zinc finger, FYVE domain containing 90.039
CASC5cancer susceptibility candidate 50.039
C11orf66chromosome 11 open reading frame 660.039
CNSTconsortin, connexin sorting protein0.038
CD2BP2CD2 (cytoplasmic tail) binding protein 20.037
ZBTB16zinc finger and BTB domain containing 160.037
RRP1Bribosomal RNA processing 1 homolog B (S. cerevisiae)0.036
SH3RF1SH3 domain containing ring finger 10.036
TUBA1Ctubulin, alpha 1c0.035
RIF1RAP1 interacting factor homolog (yeast)0.034
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.034
CKS2CDC28 protein kinase regulatory subunit 20.032
SPRED1sprouty-related, EVH1 domain containing 10.031
SORBS1sorbin and SH3 domain containing 10.031
MED26mediator complex subunit 260.031
XIRP1xin actin-binding repeat containing 10.030
TBC1D17TBC1 domain family, member 170.030
GIPC1GIPC PDZ domain containing family, member 10.029
BAIAP2BAI1-associated protein 20.028
AKT2v-akt murine thymoma viral oncogene homolog 20.027
EEF2Keukaryotic elongation factor-2 kinase0.026
PLXNB2plexin B20.025
RRS1RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)0.025
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like0.025
TSC22D4TSC22 domain family, member 40.025
OXSR1oxidative-stress responsive 10.025
TOPBP1topoisomerase (DNA) II binding protein 10.025
GAS7growth arrest-specific 70.024
SGOL2shugoshin-like 2 (S. pombe)0.024
CCNB2cyclin B20.024
CSNK2A2casein kinase 2, alpha prime polypeptide0.024
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.732
Map3k14mitogen-activated protein kinase kinase kinase 140.387
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.293
Lrrk2leucine-rich repeat kinase 20.287
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.236
Dlg4discs, large homolog 4 (Drosophila)0.207
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.169
Ltalymphotoxin A0.147
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.120
Ighimmunoglobulin heavy chain complex0.091
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.057
Hspa1bheat shock protein 1B0.047
Tnftumor necrosis factor0.042
Ltblymphotoxin B0.030
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.030
Il7interleukin 70.029
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.027
Cdk1cyclin-dependent kinase 10.027
Toxthymocyte selection-associated high mobility group box0.026
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.022
Plxna4plexin A40.021
Ccna2cyclin A20.021
Nedd4lneural precursor cell expressed, developmentally down-regulated gene 4-like0.020
Prc1protein regulator of cytokinesis 10.020
Cxcr5chemokine (C-X-C motif) receptor 50.019
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.018
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.018
Rab25RAB25, member RAS oncogene family0.015
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.015
Ifnginterferon gamma0.014
Cxcl13chemokine (C-X-C motif) ligand 130.012
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.012
Tnfsf14tumor necrosis factor (ligand) superfamily, member 140.012
Tcfcp2l1transcription factor CP2-like 10.011
Polr2dpolymerase (RNA) II (DNA directed) polypeptide D0.011
1810031K17RikRIKEN cDNA 1810031K17 gene0.011
Ripk4receptor-interacting serine-threonine kinase 40.011
Cct5chaperonin containing Tcp1, subunit 5 (epsilon)0.011
Il4interleukin 40.011
Plk1polo-like kinase 1 (Drosophila)0.011
Siah2seven in absentia 20.010
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism