The network for 'anterior posterior pattern specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

anterior posterior pattern specification

The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

NameDescriptionProbabilityFunc Analog Organism
Tpm2tropomyosin 2, beta0.765
Acta2smooth muscle alpha-actin0.750
Col12a1collagen, type XII, alpha 10.591
Myl9myosin, light chain 9, regulatory0.458
Fgfr2fibroblast growth factor receptor 20.384
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.310
Tpm3tropomyosin 3, gamma0.284
Rac1ras-related C3 botulinum toxin substrate 10.277
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.239
Tgfbr2transforming growth factor, beta receptor II0.234
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.233
Actg2actin, gamma 2, smooth muscle, enteric0.225
Igfbp5insulin-like growth factor binding protein 50.209
Hoxb7homeo box B70.204
Clic4chloride intracellular channel 40.201
Stxbp1syntaxin binding protein 10.200
Azin1antizyme inhibitor 10.199
Golph3golgi phosphoprotein 3 (coat-protein)0.190
Lbrlamin B receptor0.188
Nlgn2neuroligin 20.184
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.178
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.176
Snap25synaptosomal-associated protein 250.175
Tcf12transcription factor 120.173
Dpf1D4, zinc and double PHD fingers family 10.170
Sox17SRY (sex determining region Y)-box 170.170
Ptprcprotein tyrosine phosphatase, receptor type, C0.166
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.165
Hckhemopoietic cell kinase0.164
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.164
Stx1asyntaxin 1A (brain)0.164
Myh11myosin, heavy chain 11, smooth muscle0.163
Pax4paired box 40.154
Notch3Notch homolog 3 (Drosophila)0.151
Baiap2BAI1-associated protein 20.151
Dlg4discs, large homolog 4 (Drosophila)0.150
Fut4fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)0.150
Lcp1lymphocyte cytosolic protein 10.145
Twist2twist homolog 2 (Drosophila)0.143
Nudt3nudix (nucleoside diphosphate linked moiety X)-type motif 30.142
Vamp2vesicle-associated membrane protein 20.139
Actr3ARP3 actin-related protein 3 homolog (yeast)0.138
RestRE1-silencing transcription factor0.138
Gsk3aglycogen synthase kinase 3 alpha0.137
Myh13myosin, heavy chain 13, skeletal muscle0.137
Sfrs2splicing factor, arginine/serine-rich 20.134
Dgkidiacylglycerol kinase, iota0.132
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.129
Mapk3mitogen activated protein kinase 30.126
Pcnaproliferating cell nuclear antigen0.125
Caskcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.123
Hk1hexokinase 10.118
Fusfusion (involved in t(12;16) in malignant liposarcoma) (human)0.118
Synrgsynergin, gamma0.117
Shox2short stature homeobox 20.116
Alx1ALX homeobox 10.114
Camk2n2calcium/calmodulin-dependent protein kinase II inhibitor 20.114
Ctxn1cortexin 10.112
MaxMYC associated factor X0.112
Eporerythropoietin receptor0.112
Sdk2sidekick homolog 2 (chicken)0.111
Rab5aRAB5A, member RAS oncogene family0.111
Mc5rmelanocortin 5 receptor0.110
Unc5bunc-5 homolog B (C. elegans)0.110
Phf12PHD finger protein 120.110
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.108
Adrm1adhesion regulating molecule 10.108
Opn1swopsin 1 (cone pigments), short-wave-sensitive0.107
Gata4GATA binding protein 40.106
Elk3ELK3, ETS-domain protein0.106
Tpm4tropomyosin 40.104
Lphn2latrophilin 20.103
Adam10ADAM metallopeptidase domain 100.103
Hoxc4homeo box C40.103
Eef1e1eukaryotic translation elongation factor 1 epsilon 10.101
Galr3galanin receptor 30.097
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.096
Txnl1thioredoxin-like 10.096
Ptov1prostate tumor overexpressed 10.095
Plac8placenta-specific 80.094
Fam65afamily with sequence similarity 65, member A0.094
Hoxb8homeo box B80.094
Klk1c10l2kallikrein 1-related peptidase c10-like 20.094
Lman1lectin, mannose-binding, 10.093
Irs1insulin receptor substrate 10.092
Acaa1bacetyl-Coenzyme A acyltransferase 1B0.091
Grid2glutamate receptor, ionotropic, delta 20.091
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.091
Slc30a1solute carrier family 30 (zinc transporter), member 10.090
Dazap2DAZ associated protein 20.090
Syn1synapsin I0.090
Tgfb3transforming growth factor, beta 30.090
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.089
Smad7SMAD family member 70.089
Prph2peripherin 20.088
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.946
par-5Protein PAR-50.610
lin-17Protein LIN-170.528
let-60Protein LET-600.259
pry-1Protein PRY-10.225
pal-1Protein PAL-10.205
hbl-1Protein HBL-10.195
mat-3Protein MAT-30.193
nhr-25Protein NHR-250.175
unc-62Protein UNC-620.175
glp-1Protein GLP-10.160
lin-45Protein LIN-450.156
bar-1Protein BAR-10.151
fkh-2Protein FKH-20.128
F39B2.1Protein F39B2.10.126
egl-46Protein EGL-460.124
elc-1Protein ELC-10.118
hlh-1Protein HLH-10.114
lmn-1Protein LMN-10.102
sel-12Protein SEL-120.102
ajm-1Protein AJM-10.101
CELE_C17H12.13Protein C17H12.130.099
cul-2Protein CUL-20.092
ceh-16Protein CEH-160.091
daf-3Protein DAF-30.081
lin-11Protein LIN-110.081
eor-1Protein EOR-10.078
ain-1Protein AIN-10.073
dsh-2Protein DSH-20.072
snr-4Protein SNR-40.071
egl-15Protein EGL-150.069
arx-7Protein ARX-70.068
egl-5Protein EGL-50.066
cam-1Protein CAM-10.062
lit-1Protein LIT-10.062
klp-15Protein KLP-150.061
nhr-67Protein NHR-670.060
pha-4Protein PHA-40.059
elt-6Protein ELT-60.057
snr-3Protein SNR-30.055
F36D4.5Protein F36D4.50.053
tbg-1Protein TBG-10.053
eor-2Protein EOR-20.053
CELE_Y46G5A.29Protein Y46G5A.290.052
mes-6Protein MES-60.052
W03F8.4Protein W03F8.40.051
unc-130Protein UNC-1300.051
B0491.1Protein B0491.10.051
unc-43Protein UNC-430.049
csn-3Protein CSN-30.049
ten-1Protein TEN-10.049
cki-1Protein CKI-10.049
swsn-6Protein SWSN-60.048
abcf-1Protein ABCF-10.048
wrm-1Protein WRM-10.046
eya-1Protein EYA-10.046
ZK512.1Protein ZK512.10.045
Y47D3A.29Protein Y47D3A.290.044
ugt-50Protein UGT-500.044
bet-1Protein BET-10.043
ref-2Protein REF-20.041
lsy-22Protein LSY-220.040
CELE_C01G10.8Protein C01G10.80.039
lin-29Protein LIN-290.039
elt-7Protein ELT-70.039
set-1Protein SET-10.039
chk-1Protein CHK-10.038
C50B8.1Protein C50B8.10.038
glh-1Protein GLH-10.037
R02F11.4Protein R02F11.40.037
ikke-1Protein IKKE-10.037
CELE_M01B12.4Protein M01B12.40.037
ceh-20Protein CEH-200.037
igcm-4Protein IGCM-40.036
par-2Protein PAR-20.035
F13B6.1Protein F13B6.10.035
par-3Protein PAR-30.034
C17H11.6Protein C17H11.60.034
ceh-13Protein CEH-130.034
unc-51Protein UNC-510.034
CELE_C16C10.4Protein C16C10.40.033
unc-73Protein UNC-730.033
T24B8.3Protein T24B8.30.032
F13D12.5Protein F13D12.50.032
ast-1Protein AST-10.031
inx-3Protein INX-30.031
rnp-1Protein RNP-10.031
smc-4Protein SMC-40.031
unc-6Protein UNC-60.030
CELE_T02C12.3Protein T02C12.30.030
snr-1Protein SNR-10.029
R03H10.2Protein R03H10.20.029
pop-1Protein POP-10.029
elb-1Protein ELB-10.029
mcm-2Protein MCM-20.029
F59E12.11Protein F59E12.110.028
mog-2Protein MOG-20.027
sma-6Protein SMA-60.027
CELE_Y57G11C.22Protein Y57G11C.220.027
egl-13Protein EGL-130.027
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
bmp4bone morphogenetic protein 40.992
ntlano tail a0.989
myf5myogenic factor 50.983
wnt4awingless-type MMTV integration site family, member 4a0.976
wnt5bwingless-type MMTV integration site family, member 5b0.975
fgf3fibroblast growth factor 30.975
wnt1wingless-type MMTV integration site family, member 10.969
oepone-eyed pinhead0.952
wnt11wingless-type MMTV integration site family, member 110.948
notch1anotch homolog 1a0.944
eomesaeomesodermin homolog a0.940
pou5f1POU domain, class 5, transcription factor 10.937
gli1GLI-Kruppel family member 10.936
hoxc8ahomeo box C8a0.935
lhx1aLIM homeobox 1a0.931
hoxb1bhomeo box B1b0.926
tbx16T-box gene 160.906
her7hairy and enhancer of split related-70.900
piwil1piwi-like 1 (Drosophila)0.900
sox2SRY-box containing gene 20.897
pax8paired box gene 80.894
cdx4caudal type homeo box transcription factor 40.890
snai1bsnail homolog 1b (Drosophila)0.888
fezf2FEZ family zinc finger 20.882
tp53tumor protein p530.875
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.873
lef1lymphocyte enhancer binding factor 10.870
otpborthopedia homolog b0.854
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.853
hoxb3ahomeo box B3a0.848
myod1myogenic differentiation 10.838
nanos3nanos homolog 30.831
cdh2cadherin 2, neuronal0.801
six4bsine oculis homeobox homolog 4b0.798
pax2apaired box gene 2a0.796
hoxb5bhomeo box B5b0.778
crip2cysteine-rich protein 20.776
tbx6T-box gene 60.775
hoxc4ahomeo box C4a0.769
aldh1a2aldehyde dehydrogenase 1 family, member A20.752
shhasonic hedgehog a0.746
gata5GATA-binding protein 50.744
her5hairy-related 50.741
jag1bjagged 1b0.740
mibmind bomb0.738
lamc1laminin, gamma 10.728
jag2jagged 20.725
hoxc10ahomeo box C10a and homeobox protein Hox-C10a-like0.713
gata4GATA-binding protein 40.710
fgfr1bfibroblast growth factor receptor 1b0.709
msxemuscle segment homeobox E0.708
ywhabltyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like0.706
crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.704
ventventral expressed homeobox0.693
pcdh8protocadherin 80.693
hoxd9ahomeo box D9a0.691
hoxd13ahomeo box D13a0.685
tbx2bT-box 2b0.676
six3bsine oculis homeobox homolog 3b0.673
rx2retinal homeobox gene 20.665
dhrs3adehydrogenase/reductase (SDR family) member 3a0.664
eng2aengrailed 2a0.661
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.654
tbx22T-box 220.653
her1hairy-related 10.649
edn1endothelin 10.646
foxp1bforkhead box P1b0.640
spry4sprouty (Drosophila) homolog 40.638
hoxb5ahomeo box B5a0.636
ndr2nodal-related 20.635
foxc1aforkhead box C1a0.634
sox17SRY-box containing gene 170.631
bmpr1aabone morphogenetic protein receptor, type 1aa0.627
meis1myeloid ecotropic viral integration 10.622
hoxb2ahomeo box B2a0.620
hoxa9ahomeo box A9a0.619
rarabretinoic acid receptor, alpha b0.613
sema3aasemaphorin 3aa0.612
tbx24T-box 240.598
tll1tolloid-like 10.596
gdnfglial cell derived neurotrophic factor0.589
brca2breast cancer 2, early onset0.579
supt6hsuppressor of Ty 6 homolog0.574
otx2orthodenticle homolog 20.573
tbx1T-box 10.571
otx1borthodenticle homolog 1b0.570
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.561
nipblbnovel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)0.560
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.559
actn3bactinin alpha 3b0.558
hoxc9ahomeo box C9a0.556
epb4.1l4erythrocyte protein band 4.1-like 40.552
emx3empty spiracles homeobox 30.551
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
eyaeyes absent0.987
BicDBicaudal D0.986
bratbrain tumor0.983
pitaCG3941 gene product from transcript CG3941-RA0.971
cicubitus interruptus0.962
orboo18 RNA-binding protein0.927
magomago nashi0.922
lolalongitudinals lacking0.906
traltrailer hitch0.899
DadDaughters against dpp0.894
Dcp1Decapping protein 10.887
smt3CG4494 gene product from transcript CG4494-RA0.887
aPKCatypical protein kinase C0.884
spn-Espindle E0.883
gbbglass bottom boat0.855
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.855
Hrb27CHeterogeneous nuclear ribonucleoprotein at 27C0.827
Rho1CG8416 gene product from transcript CG8416-RB0.811
spensplit ends0.798
par-6CG5884 gene product from transcript CG5884-RA0.756
phlpole hole0.743
stanstarry night0.731
par-1CG8201 gene product from transcript CG8201-RA0.716
sosine oculis0.668
Src64BSrc oncogene at 64B0.663
ovoCG6824 gene product from transcript CG6824-RE0.642
mxcmulti sex combs0.604
sec5CG8843 gene product from transcript CG8843-RA0.563
Hel25EHelicase at 25E0.562
bowlbrother of odd with entrails limited0.545
fkhfork head0.519
hydhyperplastic discs0.517
Su(H)Suppressor of Hairless0.514
slp1sloppy paired 10.512
Su(z)12CG8013 gene product from transcript CG8013-RA0.506
CG11188CG11188 gene product from transcript CG11188-RA0.493
ksrkinase suppressor of ras0.491
Syx1ASyntaxin 1A0.487
slmbsupernumerary limbs0.478
LanALaminin A0.444
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.959
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.941
SMAD2SMAD family member 20.299
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.297
JAG1jagged 10.219
SMAD4SMAD family member 40.216
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.210
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.200
CREBBPCREB binding protein0.193
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.124
HOXB5homeobox B50.109
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.108
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.092
BCORBCL6 corepressor0.090
NOTCH1notch 10.080
MEOX2mesenchyme homeobox 20.079
BMI1BMI1 polycomb ring finger oncogene0.073
SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.071
EIF4A3eukaryotic translation initiation factor 4A30.070
ATF3activating transcription factor 30.067
FN1fibronectin 10.064
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.062
CDC27cell division cycle 27 homolog (S. cerevisiae)0.059
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.056
GSK3Bglycogen synthase kinase 3 beta0.054
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.053
HOXD9homeobox D90.051
HOXA10homeobox A100.048
LRP6low density lipoprotein receptor-related protein 60.047
BMPR1Abone morphogenetic protein receptor, type IA0.046
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.046
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.043
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.040
PSEN1presenilin 10.039
TP53tumor protein p530.035
CLNS1Achloride channel, nucleotide-sensitive, 1A0.032
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.031
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.031
SRPK2SRSF protein kinase 20.030
NOTCH3notch 30.030
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.029
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.029
HOXA5homeobox A50.029
HDAC4histone deacetylase 40.028
SNAP25synaptosomal-associated protein, 25kDa0.028
FOXA2forkhead box A20.028
GATA4GATA binding protein 40.028
QKIquaking homolog, KH domain RNA binding (mouse)0.027
SRSF1serine/arginine-rich splicing factor 10.026
HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2)0.026
HOXC6homeobox C60.025
HOXB9homeobox B90.025
FLNAfilamin A, alpha0.025
TRIP6thyroid hormone receptor interactor 60.024
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.024
PMLpromyelocytic leukemia0.024
MEIS1Meis homeobox 10.024
HOXA11homeobox A110.024
HOXB6homeobox B60.023
PAX1paired box 10.023
NCKAP1NCK-associated protein 10.022
HOXB3homeobox B30.021
SKIv-ski sarcoma viral oncogene homolog (avian)0.021
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.021
MLLT1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.021
WNT3Awingless-type MMTV integration site family, member 3A0.020
HOXA4homeobox A40.020
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.020
SMAD3SMAD family member 30.020
ZHX1zinc fingers and homeoboxes 10.020
PBX1pre-B-cell leukemia homeobox 10.020
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.020
ANAPC7anaphase promoting complex subunit 70.019
MDC1mediator of DNA-damage checkpoint 10.019
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.019
PDX1pancreatic and duodenal homeobox 10.018
RHOAras homolog gene family, member A0.018
ARAFv-raf murine sarcoma 3611 viral oncogene homolog0.018
OCRLoculocerebrorenal syndrome of Lowe0.018
APPBP2amyloid beta precursor protein (cytoplasmic tail) binding protein 20.017
ANAPC5anaphase promoting complex subunit 50.017
CBX8chromobox homolog 80.017
ACVR1activin A receptor, type I0.017
RBX1ring-box 1, E3 ubiquitin protein ligase0.017
MSX1msh homeobox 10.016
FLNBfilamin B, beta0.016
SORBS3sorbin and SH3 domain containing 30.016
SPTBN1spectrin, beta, non-erythrocytic 10.015
SCHIP1schwannomin interacting protein 10.015
ZMYND11zinc finger, MYND-type containing 110.015
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.015
CCNT1cyclin T10.015
XIAPX-linked inhibitor of apoptosis0.015
PCGF2polycomb group ring finger 20.015
MDM2Mdm2 p53 binding protein homolog (mouse)0.015
HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 10.015
PKM2pyruvate kinase, muscle0.014
CBX4chromobox homolog 40.014
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism