The network for 'negative regulation of phagocytosis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of phagocytosis

Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.

NameDescriptionProbabilityFunc Analog Organism
Ndufa2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 20.020
Tomm7translocase of outer mitochondrial membrane 7 homolog (yeast)0.018
Atp5lATP synthase, H+ transporting, mitochondrial F0 complex, subunit G0.017
Top1topoisomerase (DNA) I0.015
Cox7ccytochrome c oxidase, subunit VIIc0.014
Churc1churchill domain containing 10.012
Psma2proteasome (prosome, macropain) subunit, alpha type 20.012
Ndufa13NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 130.012
Atp5j2ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F20.011
RGD1309735similar to CG14977-PA0.011
Timm8btranslocase of inner mitochondrial membrane 8 homolog b (yeast)0.011
Ndufs5NADH dehydrogenase (ubiquinone) Fe-S protein 50.011
Atp6v1fATPase, H transporting, lysosomal V1 subunit F0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
C1QAcomplement component 1, q subcomponent, A chain0.999
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.949
C1QCcomplement component 1, q subcomponent, C chain0.896
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.766
TFF1trefoil factor 10.730
SHC1SHC (Src homology 2 domain containing) transforming protein 10.706
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.682
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.646
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.635
ENGendoglin0.524
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.514
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.501
HIPK2homeodomain interacting protein kinase 20.473
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.416
C1QBcomplement component 1, q subcomponent, B chain0.414
PTPN6protein tyrosine phosphatase, non-receptor type 60.407
SYKspleen tyrosine kinase0.391
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.357
PILRApaired immunoglobin-like type 2 receptor alpha0.347
HK3hexokinase 3 (white cell)0.286
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.267
SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.259
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.224
HIPK3homeodomain interacting protein kinase 30.223
PXNpaxillin0.200
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.194
SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin0.182
INPP5Dinositol polyphosphate-5-phosphatase, 145kDa0.163
RIN1Ras and Rab interactor 10.159
LAIR1leukocyte-associated immunoglobulin-like receptor 10.158
MAP3K1mitogen-activated protein kinase kinase kinase 10.151
TGFBR1transforming growth factor, beta receptor 10.148
SPRR2Asmall proline-rich protein 2A0.145
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.135
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.134
MARCOmacrophage receptor with collagenous structure0.129
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.121
BCAR1breast cancer anti-estrogen resistance 10.119
WDR83WD repeat domain 830.119
CD33CD33 molecule0.111
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.108
MAVSmitochondrial antiviral signaling protein0.103
UBASH3Bubiquitin associated and SH3 domain containing B0.099
FCGR2CFc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)0.096
LILRB3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.092
MYH9myosin, heavy chain 9, non-muscle0.087
WASF1WAS protein family, member 10.086
MUC1mucin 1, cell surface associated0.077
PTAFRplatelet-activating factor receptor0.074
SOS1son of sevenless homolog 1 (Drosophila)0.074
MSH4mutS homolog 4 (E. coli)0.072
ZYXzyxin0.070
CD300CCD300c molecule0.069
FSTL1follistatin-like 10.068
PTPN11protein tyrosine phosphatase, non-receptor type 110.065
FCN1ficolin (collagen/fibrinogen domain containing) 10.062
MSR1macrophage scavenger receptor 10.060
ABI2abl-interactor 20.058
STAB1stabilin 10.058
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.056
FYNFYN oncogene related to SRC, FGR, YES0.056
MPOmyeloperoxidase0.054
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.053
DYNLL1dynein, light chain, LC8-type 10.053
PRPF6PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)0.052
SMAD2SMAD family member 20.051
CYTH4cytohesin 40.050
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.050
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.048
EPORerythropoietin receptor0.048
TREM2triggering receptor expressed on myeloid cells 20.045
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.045
ZFYVE9zinc finger, FYVE domain containing 90.045
SMAD3SMAD family member 30.044
ADAM19ADAM metallopeptidase domain 190.044
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.043
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.043
FLNAfilamin A, alpha0.042
CTSGcathepsin G0.040
SIGLEC5sialic acid binding Ig-like lectin 50.040
SIGLEC10sialic acid binding Ig-like lectin 100.040
CREBBPCREB binding protein0.039
CAMPcathelicidin antimicrobial peptide0.039
TGFB3transforming growth factor, beta 30.039
SORBS3sorbin and SH3 domain containing 30.039
CEACAM3carcinoembryonic antigen-related cell adhesion molecule 30.038
DYRK1Bdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B0.038
FPR1formyl peptide receptor 10.038
GOLM1golgi membrane protein 10.037
CLEC4GC-type lectin domain family 4, member G0.037
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.036
THBS1thrombospondin 10.036
EGFRepidermal growth factor receptor0.036
SPI1spleen focus forming virus (SFFV) proviral integration oncogene spi10.035
CFPcomplement factor properdin0.035
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.034
SND1staphylococcal nuclease and tudor domain containing 10.034
C5AR1complement component 5a receptor 10.033
APOBRapolipoprotein B receptor0.033
MSH5mutS homolog 5 (E. coli)0.032
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Myl9myosin, light polypeptide 9, regulatory0.957
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.954
Dok1docking protein 10.952
Inpp5dinositol polyphosphate-5-phosphatase D0.940
Ptmaprothymosin alpha0.879
Taglntransgelin0.799
Ric8resistance to inhibitors of cholinesterase 8 homolog (C. elegans)0.744
Cnn2calponin 20.713
Acta2actin, alpha 2, smooth muscle, aorta0.691
Rps3ribosomal protein S30.592
Apoeapolipoprotein E0.573
ArhgdiaRho GDP dissociation inhibitor (GDI) alpha0.547
Dok2docking protein 20.537
Vaspvasodilator-stimulated phosphoprotein0.512
Rhogras homolog gene family, member G0.499
Csf1rcolony stimulating factor 1 receptor0.498
Elaneelastase, neutrophil expressed0.451
Gnb2guanine nucleotide binding protein (G protein), beta 20.444
Rps2ribosomal protein S20.401
Rplp0ribosomal protein, large, P00.396
Eef1a1eukaryotic translation elongation factor 1 alpha 10.391
Csf1colony stimulating factor 1 (macrophage)0.385
CebpeCCAAT/enhancer binding protein (C/EBP), epsilon0.366
Dok3docking protein 30.347
Tbxas1thromboxane A synthase 1, platelet0.322
TyrobpTYRO protein tyrosine kinase binding protein0.321
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.320
Cnn1calponin 10.315
Trp53transformation related protein 530.302
Unc93b1unc-93 homolog B1 (C. elegans)0.301
Ilkintegrin linked kinase0.244
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.238
Lyz2lysozyme 20.231
Smtnsmoothelin0.230
Myo1cmyosin IC0.229
BrafBraf transforming gene0.212
Selpselectin, platelet0.208
Ncf1neutrophil cytosolic factor 10.199
Rpl6ribosomal protein L60.199
Crtapcartilage associated protein0.193
Hckhemopoietic cell kinase0.192
Hmgb1high mobility group box 10.183
Csrp1cysteine and glycine-rich protein 10.178
Crip1cysteine-rich protein 1 (intestinal)0.176
Tgfb1i1transforming growth factor beta 1 induced transcript 10.171
Actn1actinin, alpha 10.167
Flnafilamin, alpha0.166
Sipa1signal-induced proliferation associated gene 10.165
Clec4a2C-type lectin domain family 4, member a20.163
Nr3c1nuclear receptor subfamily 3, group C, member 10.158
Mylkmyosin, light polypeptide kinase0.155
Stat3signal transducer and activator of transcription 30.154
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.152
Stmn1stathmin 10.149
Tlr4toll-like receptor 40.149
Myh9myosin, heavy polypeptide 9, non-muscle0.146
Cotl1coactosin-like 1 (Dictyostelium)0.144
Siglec1sialic acid binding Ig-like lectin 1, sialoadhesin0.135
Cdkn1bcyclin-dependent kinase inhibitor 1B0.133
Wdr1WD repeat domain 10.131
Pcolceprocollagen C-endopeptidase enhancer protein0.131
Hnrpdlheterogeneous nuclear ribonucleoprotein D-like0.130
Rpl28ribosomal protein L280.130
C3ar1complement component 3a receptor 10.130
Kctd10potassium channel tetramerisation domain containing 100.129
Ccl24chemokine (C-C motif) ligand 240.125
AF251705cDNA sequence AF2517050.125
Mfn2mitofusin 20.122
Phldb2pleckstrin homology-like domain, family B, member 20.121
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.121
Rps5ribosomal protein S50.119
Sfpi1SFFV proviral integration 10.119
Msr1macrophage scavenger receptor 10.119
Tmpothymopoietin0.116
Nucks1nuclear casein kinase and cyclin-dependent kinase substrate 10.115
Rpl7aribosomal protein L7A0.114
C1qbcomplement component 1, q subcomponent, beta polypeptide0.108
Anp32eacidic (leucine-rich) nuclear phosphoprotein 32 family, member E0.105
Ptk2PTK2 protein tyrosine kinase 20.104
Actg2actin, gamma 2, smooth muscle, enteric0.102
Lmnalamin A0.101
Tpm1tropomyosin 1, alpha0.101
Itgb1integrin beta 1 (fibronectin receptor beta)0.100
Myh11myosin, heavy polypeptide 11, smooth muscle0.100
H2afzH2A histone family, member Z0.098
Tpm4tropomyosin 40.097
Aoahacyloxyacyl hydrolase0.093
Rpl8ribosomal protein L80.093
Cr2complement receptor 20.091
Trem3triggering receptor expressed on myeloid cells 30.091
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.090
Arhgef1Rho guanine nucleotide exchange factor (GEF) 10.090
Rplp1ribosomal protein, large, P10.089
Tgfbr2transforming growth factor, beta receptor II0.087
Flt3FMS-like tyrosine kinase 30.087
Vpreb3pre-B lymphocyte gene 30.087
Clec5aC-type lectin domain family 5, member a0.084
Cxcr2chemokine (C-X-C motif) receptor 20.083
Mapkapk2MAP kinase-activated protein kinase 20.083
Fpr1formyl peptide receptor 10.081
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism