Process View
The network for 'immune response activating signal transduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Il2rg | interleukin 2 receptor, gamma | 0.473 | |
Myo1f | myosin IF | 0.448 | |
Cd86 | CD86 molecule | 0.420 | |
Sash3 | SAM and SH3 domain containing 3 | 0.318 | |
Hcls1 | hematopoietic cell specific Lyn substrate 1 | 0.252 | |
Vav1 | vav 1 guanine nucleotide exchange factor | 0.227 | |
Fgr | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.190 | |
Clec12a | C-type lectin domain family 12, member A | 0.188 | |
Inpp5d | inositol polyphosphate-5-phosphatase D | 0.183 | |
Igsf6 | immunoglobulin superfamily, member 6 | 0.158 | |
Cd3g | CD3 molecule, gamma | 0.149 | |
Arhgap9 | Rho GTPase activating protein 9 | 0.127 | |
Sp140 | SP140 nuclear body protein | 0.113 | |
Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1 | 0.112 | |
Il1b | interleukin 1 beta | 0.103 | |
Casp1 | caspase 1 | 0.100 | |
Btk | Bruton agammaglobulinemia tyrosine kinase | 0.093 | |
Cd38 | CD38 molecule | 0.083 | |
Itgb2 | integrin, beta 2 | 0.081 | |
Arl11 | ADP-ribosylation factor-like 11 | 0.081 | |
Cd37 | CD37 molecule | 0.079 | |
Dtx3l | deltex 3-like (Drosophila) | 0.077 | |
Nr1d2 | nuclear receptor subfamily 1, group D, member 2 | 0.070 | |
Arrdc1 | arrestin domain containing 1 | 0.070 | |
Sla | src-like adaptor | 0.067 | |
Plek | pleckstrin | 0.066 | |
Ccr5 | chemokine (C-C motif) receptor 5 | 0.066 | |
Ciita | class II, major histocompatibility complex, transactivator | 0.064 | |
Ets1 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 0.061 | |
Syk | spleen tyrosine kinase | 0.059 | |
LOC687856 | similar to Myeloid cell surface antigen CD33 precursor (Siglec-3) | 0.057 | |
Hck | hemopoietic cell kinase | 0.057 | |
RGD1559588 | similar to cell surface receptor FDFACT | 0.056 | |
Tifa | TRAF-interacting protein with forkhead-associated domain | 0.054 | |
Sirpa | signal-regulatory protein alpha | 0.053 | |
Rac2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 0.053 | |
Cst7 | cystatin F (leukocystatin) | 0.052 | |
Arhgap25 | Rho GTPase activating protein 25 | 0.051 | |
Dbp | D site of albumin promoter (albumin D-box) binding protein | 0.049 | |
Ptafr | platelet-activating factor receptor | 0.048 | |
Ccr1 | chemokine (C-C motif) receptor 1 | 0.047 | |
Mca32 | mast cell antigen 32 | 0.045 | |
Ncf4 | neutrophil cytosolic factor 4 | 0.044 | |
Lcn2 | lipocalin 2 | 0.044 | |
Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.044 | |
Unc93b1 | unc-93 homolog B1 (C. elegans) | 0.043 | |
Slfn2 | schlafen 2 | 0.040 | |
Pla2g4a | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.038 | |
Slfn8 | schlafen 8 | 0.038 | |
Ptprc | protein tyrosine phosphatase, receptor type, C | 0.037 | |
Stk10 | serine/threonine kinase 10 | 0.036 | |
Cd8b | CD8b molecule | 0.036 | |
Tnfaip8l2 | tumor necrosis factor, alpha-induced protein 8-like 2 | 0.036 | |
Plcg2 | phospholipase C, gamma 2 | 0.035 | |
Cybb | cytochrome b-245, beta polypeptide | 0.034 | |
Adam17 | ADAM metallopeptidase domain 17 | 0.033 | |
Ctse | cathepsin E | 0.033 | |
Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.033 | |
Itgal | integrin, alpha L | 0.032 | |
Ccl4 | chemokine (C-C motif) ligand 4 | 0.032 | |
Bcl2a1d | B-cell leukemia/lymphoma 2 related protein A1d | 0.032 | |
Vcam1 | vascular cell adhesion molecule 1 | 0.031 | |
Glipr1 | GLI pathogenesis-related 1 | 0.031 | |
Fcgr1a | Fc fragment of IgG, high affinity Ia, receptor (CD64) | 0.030 | |
Itgam | integrin, alpha M | 0.030 | |
Mmp12 | matrix metallopeptidase 12 | 0.030 | |
Rhog | ras homolog gene family, member G (rho G) | 0.029 | |
Cd247 | Cd247 molecule | 0.029 | |
Cp | ceruloplasmin | 0.029 | |
Clec4a1 | C-type lectin domain family 4, member a1 | 0.028 | |
Cd53 | Cd53 molecule | 0.028 | |
Slpi | secretory leukocyte peptidase inhibitor | 0.027 | |
Abi3 | ABI family, member 3 | 0.026 | |
Art2 | ADP-ribosyltransferase 2 | 0.026 | |
LOC24906 | RoBo-1 | 0.026 | |
Dock8 | dedicator of cytokinesis 8 | 0.025 | |
Ly86 | lymphocyte antigen 86 | 0.025 | |
Slc15a3 | solute carrier family 15, member 3 | 0.024 | |
Lpl | lipoprotein lipase | 0.024 | |
Lcp1 | lymphocyte cytosolic protein 1 | 0.024 | |
Cish | cytokine inducible SH2-containing protein | 0.023 | |
Olr1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.023 | |
Ifi204 | interferon activated gene 204 | 0.022 | |
Mov10 | Moloney leukemia virus 10 | 0.022 | |
Adrb2 | adrenergic, beta-2-, receptor, surface | 0.022 | |
Lpxn | leupaxin | 0.021 | |
Ctla2a | cytotoxic T lymphocyte-associated protein 2 alpha | 0.021 | |
Cd180 | CD180 molecule | 0.021 | |
Cd14 | CD14 molecule | 0.021 | |
Lcp2 | lymphocyte cytosolic protein 2 | 0.020 | |
St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.020 | |
Tlr2 | toll-like receptor 2 | 0.019 | |
Ifng | interferon gamma | 0.019 | |
Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.019 | |
Fabp4 | fatty acid binding protein 4, adipocyte | 0.019 | |
Il2rb | interleukin 2 receptor, beta | 0.018 | |
Zfp36 | zinc finger protein 36 | 0.017 | |
Ceacam10 | carcinoembryonic antigen-related cell adhesion molecule 10 | 0.017 | |
Traf3ip3 | TRAF3 interacting protein 3 | 0.017 | |
RGD1561143 | similar to cell surface receptor FDFACT | 0.017 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
LOC566708 | FL cytokine receptor-like | 0.487 | |
ighm | immunoglobulin heavy constant mu and immunoglobulin heavy constant mu | 0.461 | |
lcp1 | lymphocyte cytosolic plastin 1 | 0.421 | |
epor | erythropoietin receptor | 0.340 | |
tlr3 | toll-like receptor 3 | 0.338 | |
pdcd2 | programmed cell death 2 | 0.198 | |
tlr9 | toll-like receptor 9 | 0.176 | |
tnfb | tumor necrosis factor b (TNF superfamily, member 2) | 0.127 | |
tbx5b | T-box 5b | 0.102 | |
ighz2 | immunoglobulin heavy constant zeta2 | 0.076 | |
LOC100151531 | zinc finger protein Gfi-1b-like | 0.074 | |
nod1 | nucleotide-binding oligomerization domain containing 1 | 0.074 | |
il22 | interleukin 22 | 0.072 | |
LOC557072 | caspase recruitment domain-containing protein 11-like | 0.069 | |
ighz | immunoglobulin heavy constant zeta | 0.068 | |
stc1l | stanniocalcin 1, like | 0.059 | |
fbln4 | fibulin 4 | 0.059 | |
ef1a | elongation factor 1-alpha | 0.058 | |
elovl4a | elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4a | 0.056 | |
abcg2c | ATP-binding cassette, sub-family G (WHITE), member 2c | 0.051 | |
irak4 | interleukin-1 receptor-associated kinase 4 | 0.050 | |
tert | telomerase reverse transcriptase | 0.043 | |
LOC100000934 | hypothetical protein LOC100000934 | 0.043 | |
tlr2 | toll-like receptor 2 | 0.042 | |
kdrl | kinase insert domain receptor like | 0.035 | |
fam20b | family with sequence similarity 20, member B (H. sapiens) | 0.033 | |
epas1b | endothelial PAS domain protein 1b | 0.033 | |
rag2 | recombination activating gene 2 | 0.031 | |
sox7 | SRY-box containing gene 7 | 0.029 | |
LOC100003330 | melanocortin-2 receptor accessory protein 2-like | 0.029 | |
gata1a | GATA binding protein 1a | 0.027 | |
fxyd1 | FXYD domain containing ion transport regulator 1 (phospholemman) | 0.026 | |
nfkbiaa | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a | 0.026 | |
aplp2 | amyloid beta (A4) precursor-like protein 2 | 0.023 | |
im:7141132 | im:7141132 | 0.021 | |
LOC563363 | cholesterol side-chain cleavage enzyme, mitochondrial-like | 0.021 | |
c1qc | complement component 1, q subcomponent, C chain | 0.021 | |
dntt | deoxynucleotidyltransferase, terminal | 0.021 | |
yrk | Yes-related kinase | 0.020 | |
itga2b | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) | 0.020 | |
kcnh2 | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 0.020 | |
card9 | caspase recruitment domain family, member 9 | 0.020 | |
pdia5 | protein disulfide isomerase family A, member 5 | 0.020 | |
wasb | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b | 0.020 | |
foxn1 | forkhead box N1 | 0.020 | |
rel | v-rel reticuloendotheliosis viral oncogene homolog | 0.019 | |
LOC100534776 | toll-like receptor 7-like | 0.019 | |
cacnb2b | calcium channel, voltage-dependent, beta 2b | 0.019 | |
grn1 | granulin 1 | 0.019 | |
tlr20f | toll-like receptor 20f | 0.019 | |
grn2 | granulin 2 | 0.019 | |
ip6k2 | inositol hexaphosphate kinase 2 | 0.019 | |
xylt1 | xylosyltransferase 1 | 0.018 | |
tlr18 | toll-like receptor 18 | 0.017 | |
cdipt | CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) | 0.017 | |
cd40lg | CD40 ligand | 0.016 | |
bhlhe40 | basic helix-loop-helix family, member e40 | 0.016 | |
ccr12.2 | chemokine (C-C motif) receptor 12.2 | 0.015 | |
fgf23 | fibroblast growth factor 23 | 0.015 | |
arl4aa | ADP-ribosylation factor-like 4aa | 0.014 | |
ecscr | endothelial cell-specific chemotaxis regulator | 0.014 | |
cdh23 | cadherin-like 23 | 0.014 | |
tlr20a | toll-like receptor 20a | 0.014 | |
nfkbiab | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b | 0.014 | |
gadd45ba | growth arrest and DNA-damage-inducible, beta a | 0.014 | |
lpp | LIM domain containing preferred translocation partner in lipoma | 0.014 | |
myd88 | myeloid differentiation primary response gene (88) | 0.013 | |
trpv6 | transient receptor potential cation channel, subfamily V, member 6 | 0.013 | |
ccr6a | chemokine (C-C motif) receptor 6a | 0.013 | |
tbx21 | T-box 21 | 0.013 | |
abcc5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.013 | |
yes1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.013 | |
LOC794824 | hypothetical protein LOC794824 | 0.013 | |
c1qb | complement component 1, q subcomponent, B chain | 0.013 | |
dnmt6 | DNA (cytosine-5-)-methyltransferase 6 | 0.012 | |
smyd3 | SET and MYND domain containing 3 | 0.012 | |
sb:cb429 | sb:cb429 | 0.012 | |
socs1 | suppressor of cytokine signaling 1 | 0.011 | |
cntn2 | contactin 2 | 0.011 | |
nos2a | nitric oxide synthase 2a, inducible | 0.011 | |
nos2b | nitric oxide synthase 2b, inducible | 0.011 | |
ftsj | FtsJ homolog 3 (E. coli) | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
PGRP-SA | Peptidoglycan recognition protein SA | 0.937 | |
grass | Gram-positive Specific Serine protease | 0.911 | |
SPE | Spatzle-Processing Enzyme | 0.799 | |
Tl | Toll | 0.686 | |
AttA | Attacin-A | 0.680 | |
modSP | modular serine protease | 0.673 | |
Sema-1b | CG6446 gene product from transcript CG6446-RA | 0.596 | |
GNBP3 | Gram-negative bacteria binding protein 3 | 0.587 | |
krz | kurtz | 0.549 | |
pum | pumilio | 0.534 | |
Rel | Relish | 0.506 | |
PGRP-SD | CG7496 gene product from transcript CG7496-RA | 0.492 | |
Spn27A | Serpin 27A | 0.460 | |
Sp7 | Serine protease 7 | 0.386 | |
CG18594 | CG18594 gene product from transcript CG18594-RA | 0.382 | |
Toll-7 | CG8595 gene product from transcript CG8595-RA | 0.369 | |
Toll-6 | CG7250 gene product from transcript CG7250-RA | 0.360 | |
GNBP1 | Gram-negative bacteria binding protein 1 | 0.311 | |
Duox | Dual oxidase | 0.302 | |
p38b | CG7393 gene product from transcript CG7393-RA | 0.291 | |
Hcf | Host cell factor | 0.284 | |
Nrx-IV | Neurexin IV | 0.273 | |
pan | pangolin | 0.262 | |
Ras64B | Ras oncogene at 64B | 0.259 | |
Dredd | Death related ced-3/Nedd2-like protein | 0.256 | |
Akt1 | CG4006 gene product from transcript CG4006-RA | 0.243 | |
foxo | forkhead box, sub-group O | 0.232 | |
Spn1 | Serine protease inhibitor 1 | 0.229 | |
PGRP-SC1b | CG8577 gene product from transcript CG8577-RA | 0.225 | |
PGRP-SC1a | CG14746 gene product from transcript CG14746-RA | 0.211 | |
Sin3A | CG8815 gene product from transcript CG8815-RC | 0.206 | |
spz | spatzle | 0.202 | |
Myd88 | CG2078 gene product from transcript CG2078-RA | 0.200 | |
rut | rutabaga | 0.200 | |
PGRP-LC | Peptidoglycan recognition protein LC | 0.200 | |
ens | ensconsin | 0.197 | |
18w | 18 wheeler | 0.193 | |
PGRP-SB1 | CG9681 gene product from transcript CG9681-RA | 0.187 | |
CG5794 | CG5794 gene product from transcript CG5794-RB | 0.185 | |
ras | raspberry | 0.181 | |
imd | immune deficiency | 0.176 | |
pirk | poor Imd response upon knock-in | 0.176 | |
JIL-1 | CG6297 gene product from transcript CG6297-RA | 0.169 | |
CG42863 | CG42863 gene product from transcript CG42863-RB | 0.164 | |
Krn | Keren | 0.162 | |
AttC | Attacin-C | 0.160 | |
Pp2B-14D | Protein phosphatase 2B at 14D | 0.154 | |
NFAT | NFAT homolog | 0.150 | |
eater | CG6124 gene product from transcript CG6124-RB | 0.149 | |
upd2 | unpaired 2 | 0.148 | |
Mtk | Metchnikowin | 0.146 | |
DptB | Diptericin B | 0.145 | |
grn | grain | 0.137 | |
Tak1 | TGF-beta activated kinase 1 | 0.136 | |
eIF6 | CG17611 gene product from transcript CG17611-RA | 0.130 | |
Mpk2 | CG5475 gene product from transcript CG5475-RB | 0.130 | |
TM9SF4 | CG7364 gene product from transcript CG7364-RA | 0.121 | |
Cat | Catalase | 0.120 | |
cv | crossveinless | 0.117 | |
ari-1 | ariadne | 0.114 | |
Sdc | Syndecan | 0.112 | |
coro | CG9446 gene product from transcript CG9446-RC | 0.110 | |
cdi | center divider | 0.106 | |
TepIII | Thiolester containing protein III | 0.106 | |
ird5 | immune response deficient 5 | 0.104 | |
lok | loki | 0.104 | |
slpr | slipper | 0.100 | |
blot | bloated tubules | 0.097 | |
Trx-2 | thioredoxin-2 | 0.094 | |
fon | fondue | 0.094 | |
Tsp42Ec | Tetraspanin 42Ec | 0.093 | |
psh | persephone | 0.093 | |
cnk | connector enhancer of ksr | 0.092 | |
pgant3 | polypeptide GalNAc transferase 3 | 0.091 | |
sno | strawberry notch | 0.089 | |
Vang | Van Gogh | 0.087 | |
bbg | big bang | 0.087 | |
shn | schnurri | 0.086 | |
PGRP-LB | Peptidoglycan recognition protein LB | 0.086 | |
mbm | mushroom body miniature | 0.086 | |
Vap-33-1 | CG5014 gene product from transcript CG5014-RB | 0.086 | |
CG13604 | CG13604 gene product from transcript CG13604-RD | 0.085 | |
CG15917 | CG15917 gene product from transcript CG15917-RA | 0.085 | |
Myo31DF | Myosin 31DF | 0.084 | |
disco | disconnected | 0.083 | |
ple | pale | 0.083 | |
Rgl | Ral guanine nucleotide exchange factor | 0.082 | |
slmb | supernumerary limbs | 0.082 | |
wdb | widerborst | 0.081 | |
spirit | Serine Protease Immune Response Integrator | 0.080 | |
ftz-f1 | ftz transcription factor 1 | 0.079 | |
Traf6 | TNF-receptor-associated factor 6 | 0.078 | |
babo | baboon | 0.078 | |
slow | slowdown | 0.077 | |
RhoGAP68F | CG6811 gene product from transcript CG6811-RA | 0.077 | |
fh | frataxin homolog | 0.077 | |
Wnt5 | Wnt oncogene analog 5 | 0.077 | |
CG10650 | CG10650 gene product from transcript CG10650-RA | 0.076 | |
He | Hemese | 0.076 | |
pcx | pecanex | 0.074 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 1.000 | |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 1.000 | |
BIRC3 | baculoviral IAP repeat containing 3 | 1.000 | |
TRAF6 | TNF receptor-associated factor 6 | 1.000 | |
GRB2 | growth factor receptor-bound protein 2 | 1.000 | |
IRAK1 | interleukin-1 receptor-associated kinase 1 | 1.000 | |
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 1.000 | |
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 1.000 | |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 1.000 | |
RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.998 | |
TRAF1 | TNF receptor-associated factor 1 | 0.997 | |
MYD88 | myeloid differentiation primary response gene (88) | 0.996 | |
LCK | lymphocyte-specific protein tyrosine kinase | 0.993 | |
SYK | spleen tyrosine kinase | 0.992 | |
FYB | FYN binding protein | 0.991 | |
PTK2 | PTK2 protein tyrosine kinase 2 | 0.991 | |
RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.990 | |
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.987 | |
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.985 | |
ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.985 | |
BCL2L1 | BCL2-like 1 | 0.980 | |
NCOA3 | nuclear receptor coactivator 3 | 0.966 | |
IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.965 | |
TNIP2 | TNFAIP3 interacting protein 2 | 0.963 | |
NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.961 | |
LAT | linker for activation of T cells | 0.951 | |
BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.946 | |
CD80 | CD80 molecule | 0.944 | |
TRAF2 | TNF receptor-associated factor 2 | 0.943 | |
BTK | Bruton agammaglobulinemia tyrosine kinase | 0.943 | |
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.939 | |
UBC | ubiquitin C | 0.935 | |
VAV1 | vav 1 guanine nucleotide exchange factor | 0.924 | |
MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.918 | |
PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.900 | |
BTN3A1 | butyrophilin, subfamily 3, member A1 | 0.898 | |
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.894 | |
CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.894 | |
BLNK | B-cell linker | 0.890 | |
TNIP1 | TNFAIP3 interacting protein 1 | 0.876 | |
CARD11 | caspase recruitment domain family, member 11 | 0.872 | |
BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.872 | |
NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.869 | |
BIRC2 | baculoviral IAP repeat containing 2 | 0.868 | |
TRAF3 | TNF receptor-associated factor 3 | 0.868 | |
CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.840 | |
LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.801 | |
PRKCA | protein kinase C, alpha | 0.799 | |
CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.796 | |
RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.793 | |
IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.790 | |
TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.769 | |
MAPK14 | mitogen-activated protein kinase 14 | 0.762 | |
LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.756 | |
BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.749 | |
DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.748 | |
MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.746 | |
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.730 | |
LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.715 | |
IFIH1 | interferon induced with helicase C domain 1 | 0.697 | |
S100A16 | S100 calcium binding protein A16 | 0.689 | |
MPDZ | multiple PDZ domain protein | 0.675 | |
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.674 | |
TLR4 | toll-like receptor 4 | 0.647 | |
ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.624 | |
BAX | BCL2-associated X protein | 0.618 | |
MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.614 | |
LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 0.612 | |
MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.611 | |
MICA | MHC class I polypeptide-related sequence A | 0.605 | |
SP100 | SP100 nuclear antigen | 0.588 | |
SQSTM1 | sequestosome 1 | 0.587 | |
RNF11 | ring finger protein 11 | 0.573 | |
NCF1 | neutrophil cytosolic factor 1 | 0.558 | |
SAMD9 | sterile alpha motif domain containing 9 | 0.555 | |
FKBP4 | FK506 binding protein 4, 59kDa | 0.553 | |
CD247 | CD247 molecule | 0.552 | |
S100A14 | S100 calcium binding protein A14 | 0.541 | |
CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.531 | |
IFI44 | interferon-induced protein 44 | 0.530 | |
SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.527 | |
PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.510 | |
SH3BP2 | SH3-domain binding protein 2 | 0.505 | |
CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.500 | |
TLR2 | toll-like receptor 2 | 0.484 | |
LRRK2 | leucine-rich repeat kinase 2 | 0.477 | |
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.477 | |
OAS1 | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 0.473 | |
FYN | FYN oncogene related to SRC, FGR, YES | 0.461 | |
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.459 | |
BCL10 | B-cell CLL/lymphoma 10 | 0.456 | |
TNF | tumor necrosis factor | 0.433 | |
STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.430 | |
CD28 | CD28 molecule | 0.419 | |
UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.418 | |
MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.408 | |
DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.386 | |
TRIM22 | tripartite motif containing 22 | 0.383 | |
S100A6 | S100 calcium binding protein A6 | 0.381 | |
LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 0.378 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Myd88 | myeloid differentiation primary response gene 88 | 1.000 | |
Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 1.000 | |
Cd19 | CD19 antigen | 1.000 | |
Pten | phosphatase and tensin homolog | 1.000 | |
Ikzf1 | IKAROS family zinc finger 1 | 0.998 | |
Sykb | spleen tyrosine kinase | 0.998 | |
Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.998 | |
Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.997 | |
Cd22 | CD22 antigen | 0.994 | |
Inpp5d | inositol polyphosphate-5-phosphatase D | 0.994 | |
Stat3 | signal transducer and activator of transcription 3 | 0.994 | |
Fasl | Fas ligand (TNF superfamily, member 6) | 0.993 | |
Itk | IL2-inducible T-cell kinase | 0.992 | |
Grb2 | growth factor receptor bound protein 2 | 0.991 | |
Igh | immunoglobulin heavy chain complex | 0.989 | |
Lat | linker for activation of T cells | 0.989 | |
Tnf | tumor necrosis factor | 0.988 | |
Apoe | apolipoprotein E | 0.987 | |
Icos | inducible T-cell co-stimulator | 0.986 | |
Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.986 | |
Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.984 | |
Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.982 | |
Ddx60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.981 | |
Il2rg | interleukin 2 receptor, gamma chain | 0.981 | |
Foxp3 | forkhead box P3 | 0.981 | |
Cd180 | CD180 antigen | 0.979 | |
Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.979 | |
Traf6 | TNF receptor-associated factor 6 | 0.978 | |
Ptk2 | PTK2 protein tyrosine kinase 2 | 0.976 | |
Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.970 | |
Fyn | Fyn proto-oncogene | 0.967 | |
Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1 | 0.966 | |
Cd44 | CD44 antigen | 0.960 | |
Cd40 | CD40 antigen | 0.957 | |
Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.956 | |
Card11 | caspase recruitment domain family, member 11 | 0.954 | |
Il2rb | interleukin 2 receptor, beta chain | 0.954 | |
Vav1 | vav 1 oncogene | 0.952 | |
Klra9 | killer cell lectin-like receptor subfamily A, member 9 | 0.951 | |
Ptprc | protein tyrosine phosphatase, receptor type, C | 0.940 | |
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.938 | |
Rxra | retinoid X receptor alpha | 0.937 | |
Prkcd | protein kinase C, delta | 0.935 | |
Btk | Bruton agammaglobulinemia tyrosine kinase | 0.935 | |
Tlr4 | toll-like receptor 4 | 0.933 | |
Cbl | Casitas B-lineage lymphoma | 0.932 | |
Fas | Fas (TNF receptor superfamily member 6) | 0.932 | |
Il7r | interleukin 7 receptor | 0.932 | |
Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.931 | |
Il10 | interleukin 10 | 0.931 | |
Irf8 | interferon regulatory factor 8 | 0.926 | |
Smad4 | MAD homolog 4 (Drosophila) | 0.910 | |
Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.909 | |
Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.897 | |
Itgax | integrin alpha X | 0.892 | |
Ifnar1 | interferon (alpha and beta) receptor 1 | 0.880 | |
Dok1 | docking protein 1 | 0.880 | |
Sfpi1 | SFFV proviral integration 1 | 0.866 | |
Blk | B lymphoid kinase | 0.865 | |
Pou2af1 | POU domain, class 2, associating factor 1 | 0.863 | |
Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.861 | |
Cdh5 | cadherin 5 | 0.858 | |
Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.858 | |
Traf2 | TNF receptor-associated factor 2 | 0.853 | |
Tcra | T-cell receptor alpha chain | 0.844 | |
Ifng | interferon gamma | 0.841 | |
Unc93b1 | unc-93 homolog B1 (C. elegans) | 0.840 | |
Ccr2 | chemokine (C-C motif) receptor 2 | 0.838 | |
Prdm1 | PR domain containing 1, with ZNF domain | 0.834 | |
Stat1 | signal transducer and activator of transcription 1 | 0.834 | |
Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.829 | |
Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.829 | |
Cd247 | CD247 antigen | 0.826 | |
Fcrla | Fc receptor-like A | 0.822 | |
Ccr1 | chemokine (C-C motif) receptor 1 | 0.821 | |
Esr1 | estrogen receptor 1 (alpha) | 0.819 | |
Irf5 | interferon regulatory factor 5 | 0.818 | |
Ikzf3 | IKAROS family zinc finger 3 | 0.817 | |
Xcr1 | chemokine (C motif) receptor 1 | 0.804 | |
Trim30a | tripartite motif-containing 30A | 0.802 | |
Pyhin1 | pyrin and HIN domain family, member 1 | 0.793 | |
Tnip1 | TNFAIP3 interacting protein 1 | 0.789 | |
Lyz2 | lysozyme 2 | 0.789 | |
Spib | Spi-B transcription factor (Spi-1/PU.1 related) | 0.784 | |
Mavs | mitochondrial antiviral signaling protein | 0.783 | |
Trp53 | transformation related protein 53 | 0.782 | |
Birc3 | baculoviral IAP repeat-containing 3 | 0.781 | |
Socs1 | suppressor of cytokine signaling 1 | 0.780 | |
Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.779 | |
Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.779 | |
Ccr6 | chemokine (C-C motif) receptor 6 | 0.775 | |
Slamf6 | SLAM family member 6 | 0.773 | |
Csf1 | colony stimulating factor 1 (macrophage) | 0.773 | |
Rel | reticuloendotheliosis oncogene | 0.762 | |
Tlr2 | toll-like receptor 2 | 0.762 | |
Cd28 | CD28 antigen | 0.758 | |
Aoah | acyloxyacyl hydrolase | 0.756 | |
Tnfrsf13c | tumor necrosis factor receptor superfamily, member 13c | 0.752 | |
Cd96 | CD96 antigen | 0.749 | |
Bcl2 | B-cell leukemia/lymphoma 2 | 0.749 |