The network for 'glomerular mesangium development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glomerular mesangium development

The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.

NameDescriptionProbabilityFunc Analog Organism
FosFBJ osteosarcoma oncogene0.979
Egr2early growth response 20.619
Egr1early growth response 10.476
Junbjun B proto-oncogene0.469
Nr4a1nuclear receptor subfamily 4, group A, member 10.444
Btg2BTG family, member 20.383
Dusp6dual specificity phosphatase 60.248
Nr4a3nuclear receptor subfamily 4, group A, member 30.065
Anxa4annexin A40.065
Ier2immediate early response 20.057
Tspan8tetraspanin 80.041
Elk3ELK3, ETS-domain protein0.039
Ptpn18protein tyrosine phosphatase, non-receptor type 180.037
Rims1regulating synaptic membrane exocytosis 10.036
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.034
Egr3early growth response 30.034
Wipf1WAS/WASL interacting protein family, member 10.033
Kcnf1potassium voltage-gated channel, subfamily F, member 10.032
Spam1sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)0.031
Wisp2WNT1 inducible signaling pathway protein 20.028
Sp110SP110 nuclear body protein0.027
Pear1platelet endothelial aggregation receptor 10.024
MdficMyoD family inhibitor domain containing0.024
Ciitaclass II, major histocompatibility complex, transactivator0.024
Olr1370olfactory receptor 13700.024
Serpinb3serine protease inhibitor B30.024
Serpinb2serpin peptidase inhibitor, clade B (ovalbumin), member 20.024
Fgfr2fibroblast growth factor receptor 20.024
Degs2degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)0.023
Rab20RAB20, member RAS oncogene family0.023
RGD1564664similar to LOC387763 protein0.023
Hapln1hyaluronan and proteoglycan link protein 10.022
Pnliprp2pancreatic lipase-related protein 20.022
Cyp11b3cytochrome P450, family 11, subfamily b, polypeptide 30.022
Npwneuropeptide W0.022
Twist2twist homolog 2 (Drosophila)0.022
Sgp158proline-rich glycoprotein (sgp158)0.022
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.021
LOC259244alpha-2u globulin PGCL30.021
Mpzl2myelin protein zero-like 20.021
Krt5keratin 50.021
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.020
Col17a1collagen, type XVII, alpha 10.020
Mc5rmelanocortin 5 receptor0.020
Cyp24a1cytochrome P450, family 24, subfamily a, polypeptide 10.020
Ltbp3latent transforming growth factor beta binding protein 30.020
Nos3nitric oxide synthase 3, endothelial cell0.019
Hoxa1homeo box A10.019
P22k15cystatin related protein 20.019
Tnmdtenomodulin0.019
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.019
Flt1FMS-related tyrosine kinase 10.019
Lgals7lectin, galactoside-binding, soluble, 70.018
Cnfncornifelin0.018
Rab34RAB34, member RAS oncogene family0.018
Has2hyaluronan synthase 20.018
Plac8placenta-specific 80.018
Ugt1a5UDP glucuronosyltransferase 1 family, polypeptide A50.017
Fut4fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)0.017
Foxs1forkhead box S10.017
Arcactivity-regulated cytoskeleton-associated protein0.017
Iqgap1IQ motif containing GTPase activating protein 10.017
Akr1c18aldo-keto reductase family 1, member C180.017
Rya3antimicrobial peptide RYA30.017
Gpr20G protein-coupled receptor 200.016
Gng11guanine nucleotide binding protein (G protein), gamma 110.016
Akap4A kinase (PRKA) anchor protein 40.016
Calm4calmodulin 40.016
Col4a3collagen, type IV, alpha 30.016
RGD1311493similar to CG13379-PA0.015
Flgfilaggrin0.015
Ltb4rleukotriene B4 receptor0.015
Lhbluteinizing hormone beta0.015
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.015
Sprr1alsmall proline-rich protein 1A-like0.015
Prom2prominin 20.015
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.015
Prr13proline rich 130.014
Klf4Kruppel-like factor 4 (gut)0.014
RT1-HaRT1 class II, locus Ha0.014
Cyr61cysteine-rich, angiogenic inducer, 610.014
Yy1YY1 transcription factor0.014
Smad9SMAD family member 90.014
Ocmoncomodulin0.014
Mybpc1myosin binding protein C, slow type0.014
Nkg7natural killer cell group 7 sequence0.014
Krtdapkeratinocyte differentiation associated protein0.014
Reg1aregenerating islet-derived 1 alpha0.014
Anxa7annexin A70.014
Pdgfbplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.014
Ust5rintegral membrane transport protein UST5r0.014
S100a6S100 calcium binding protein A60.014
Ntn1netrin 10.014
Itpr3inositol 1,4,5-triphosphate receptor, type 30.014
Krt14keratin 140.013
Il6interleukin 60.013
Plb1phospholipase B10.013
Slc44a1solute carrier family 44, member 10.013
Gmfgglia maturation factor, gamma0.013
Rxraretinoid X receptor alpha0.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.497
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.042
CFL1cofilin 1 (non-muscle)0.038
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.012
BMPR1Abone morphogenetic protein receptor, type IA0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.931
Foxc2forkhead box C20.889
Fgfr2fibroblast growth factor receptor 20.878
Shhsonic hedgehog0.771
Bmp4bone morphogenetic protein 40.757
Pax2paired box gene 20.756
Foxc1forkhead box C10.724
Gli3GLI-Kruppel family member GLI30.660
Vegfavascular endothelial growth factor A0.582
Nos3nitric oxide synthase 3, endothelial cell0.559
Ctnnb1catenin (cadherin associated protein), beta 10.495
Tbx1T-box 10.436
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.433
Bcl2B-cell leukemia/lymphoma 20.368
Tgfb2transforming growth factor, beta 20.365
Efnb2ephrin B20.323
Jag1jagged 10.244
Meox2mesenchyme homeobox 20.239
Psen1presenilin 10.213
Notch2Notch gene homolog 2 (Drosophila)0.201
Kdrkinase insert domain protein receptor0.197
Fgf8fibroblast growth factor 80.171
Notch1Notch gene homolog 1 (Drosophila)0.162
Pax3paired box gene 30.160
Runx2runt related transcription factor 20.151
Fgfr1fibroblast growth factor receptor 10.143
Otx2orthodenticle homolog 2 (Drosophila)0.134
Prrx1paired related homeobox 10.129
Eya1eyes absent 1 homolog (Drosophila)0.129
Flt4FMS-like tyrosine kinase 40.124
Nab2Ngfi-A binding protein 20.120
Msx1homeobox, msh-like 10.118
Ntf3neurotrophin 30.101
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.100
Hmx3H6 homeobox 30.090
Pax8paired box gene 80.070
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.069
Pax6paired box gene 60.068
Hand2heart and neural crest derivatives expressed transcript 20.067
Pitx2paired-like homeodomain transcription factor 20.061
Gata6GATA binding protein 60.058
Dlx5distal-less homeobox 50.058
Tcfap2atranscription factor AP-2, alpha0.056
Itgb1integrin beta 1 (fibronectin receptor beta)0.054
Gbx2gastrulation brain homeobox 20.051
Tgfbr2transforming growth factor, beta receptor II0.047
Ror2receptor tyrosine kinase-like orphan receptor 20.046
Tcf21transcription factor 210.045
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.044
Csf1colony stimulating factor 1 (macrophage)0.044
FosFBJ osteosarcoma oncogene0.044
Gdnfglial cell line derived neurotrophic factor0.044
Lmx1aLIM homeobox transcription factor 1 alpha0.043
Nkx2-1NK2 homeobox 10.041
Pbx1pre B-cell leukemia transcription factor 10.041
Lhx1LIM homeobox protein 10.041
Emx2empty spiracles homolog 2 (Drosophila)0.036
Rxraretinoid X receptor alpha0.034
Lmx1bLIM homeobox transcription factor 1 beta0.032
Foxg1forkhead box G10.032
Hes1hairy and enhancer of split 1 (Drosophila)0.030
Hoxa1homeobox A10.029
Hand1heart and neural crest derivatives expressed transcript 10.026
Rarbretinoic acid receptor, beta0.026
Otx1orthodenticle homolog 1 (Drosophila)0.026
Smosmoothened homolog (Drosophila)0.026
Pou4f2POU domain, class 4, transcription factor 20.024
Egr1early growth response 10.023
Sox7SRY-box containing gene 70.023
Zeb1zinc finger E-box binding homeobox 10.022
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.022
Ldb2LIM domain binding 20.022
Gata4GATA binding protein 40.022
Ptenphosphatase and tensin homolog0.020
Hoxa2homeobox A20.019
Dll1delta-like 1 (Drosophila)0.018
Fgfr3fibroblast growth factor receptor 30.018
Tbx2T-box 20.017
Gscgoosecoid homeobox0.016
Wt1Wilms tumor 1 homolog0.016
Ptgs2prostaglandin-endoperoxide synthase 20.015
Cdh5cadherin 50.015
Wnt4wingless-related MMTV integration site 40.014
JunJun oncogene0.014
Chd7chromodomain helicase DNA binding protein 70.014
Evx2even skipped homeotic gene 2 homolog0.014
Snai1snail homolog 1 (Drosophila)0.013
Bnc1basonuclin 10.013
Amhanti-Mullerian hormone0.013
Bmp2bone morphogenetic protein 20.013
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.013
Emx1empty spiracles homolog 1 (Drosophila)0.012
Ptch1patched homolog 10.012
Psen2presenilin 20.012
Nognoggin0.012
Sox9SRY-box containing gene 90.011
Egr2early growth response 20.011
Flt1FMS-like tyrosine kinase 10.011
Sox2SRY-box containing gene 20.010
Dmrt3doublesex and mab-3 related transcription factor 30.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism