The network for 'salivary gland development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

salivary gland development

The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.

NameDescriptionProbabilityFunc Analog Organism
Edn1endothelin 10.183
Prkcdprotein kinase C, delta0.170
Nfibnuclear factor I/B0.166
Igfbp5insulin-like growth factor binding protein 50.156
Bcl2B-cell CLL/lymphoma 20.150
Mcammelanoma cell adhesion molecule0.141
Cd4Cd4 molecule0.138
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.118
Fgfr2fibroblast growth factor receptor 20.110
Tgfbr2transforming growth factor, beta receptor II0.103
Pik3ap1phosphoinositide-3-kinase adaptor protein 10.100
Mpp3membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)0.100
Rab10RAB10, member RAS oncogene family0.099
Col12a1collagen, type XII, alpha 10.098
Bin1bridging integrator 10.097
Fut1fucosyltransferase 10.097
Marcksmyristoylated alanine rich protein kinase C substrate0.093
Cd14CD14 molecule0.089
Snai1snail homolog 1 (Drosophila)0.088
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.086
Socs3suppressor of cytokine signaling 30.082
CblCas-Br-M (murine) ecotropic retroviral transforming sequence0.080
Il1r1interleukin 1 receptor, type I0.079
Foxs1forkhead box S10.072
Pftk1PFTAIRE protein kinase 10.072
Acvr1activin A receptor, type I0.069
Robo1roundabout homolog 1 (Drosophila)0.067
Notch2Notch homolog 2 (Drosophila)0.067
Elf1E74-like factor 10.067
Olfml2bolfactomedin-like 2B0.065
Prf1perforin 1 (pore forming protein)0.065
Ptprcprotein tyrosine phosphatase, receptor type, C0.065
Thbdthrombomodulin0.065
Sirpasignal-regulatory protein alpha0.064
Apoeapolipoprotein E0.064
Slc15a3solute carrier family 15, member 30.064
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.063
Fgfr1Fibroblast growth factor receptor 10.062
Slit3slit homolog 3 (Drosophila)0.061
Col5a1collagen, type V, alpha 10.061
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.061
Prp15proline-rich protein 150.059
Clec11aC-type lectin domain family 11, member a0.058
Lamc1laminin, gamma 10.058
Plauplasminogen activator, urokinase0.058
Ptpn14protein tyrosine phosphatase, non-receptor type 140.058
Rab3il1RAB3A interacting protein (rabin3)-like 10.057
Rabac1Rab acceptor 1 (prenylated)0.056
C1qtnf6C1q and tumor necrosis factor related protein 60.054
Slit1slit homolog 1 (Drosophila)0.054
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.054
Cd37CD37 molecule0.054
Lcp1lymphocyte cytosolic protein 10.053
TcrbT-cell receptor beta chain0.053
Oclnoccludin0.052
Il1binterleukin 1 beta0.052
Ptprsprotein tyrosine phosphatase, receptor type, S0.051
Cd86CD86 molecule0.051
Gnrhrgonadotropin releasing hormone receptor0.051
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.051
Ccdc102acoiled-coil domain containing 102A0.050
Stat6signal transducer and activator of transcription 60.050
Muc1mucin 1, cell surface associated0.050
Sema3asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A0.050
Plekpleckstrin0.050
PawrPRKC, apoptosis, WT1, regulator0.050
Bmp3bone morphogenetic protein 30.049
Ptpn18protein tyrosine phosphatase, non-receptor type 180.048
Myo1fmyosin IF0.048
Mrasmuscle RAS oncogene homolog0.048
Gna11guanine nucleotide binding protein, alpha 110.048
Ap2a1adaptor-related protein complex 2, alpha 1 subunit0.048
Ptch1patched homolog 1 (Drosophila)0.047
Gdf11growth differentiation factor 110.047
Myo1gmyosin IG0.047
Ehfets homologous factor0.047
Galntl1UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 10.047
Epas1endothelial PAS domain protein 10.047
Msnmoesin0.046
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.046
Mobkl2aMOB1, Mps One Binder kinase activator-like 2A (yeast)0.045
Prrx1paired related homeobox 10.045
Amphamphiphysin0.045
Sstr4somatostatin receptor 40.045
Slc2a13solute carrier family 2 (facilitated glucose transporter), member 130.045
Pik3cdphosphoinositide-3-kinase, catalytic, delta polypeptide0.045
Mpp2membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)0.045
Laptm5lysosomal protein transmembrane 50.044
Esr1estrogen receptor 10.044
AxlAxl receptor tyrosine kinase0.044
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.043
Igh-6immunoglobulin heavy chain 60.043
Il2rginterleukin 2 receptor, gamma0.043
Utrnutrophin0.043
Tcfe2atranscription factor E2a0.043
Inpp5dinositol polyphosphate-5-phosphatase D0.042
LOC690418similar to Acidic proline-rich protein PRP25 precursor0.042
KlKlotho0.042
Map3k3mitogen activated protein kinase kinase kinase 30.042
Gata6GATA binding protein 60.042
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
LanB2Laminin B20.987
mewmultiple edematous wings0.957
wbwing blister0.927
stumpsCG31317 gene product from transcript CG31317-RC0.902
wgwingless0.882
ushu-shaped0.880
fz2frizzled 20.856
E(spl)Enhancer of split0.819
hkbhuckebein0.803
tintinman0.801
twitwist0.794
HLHmbetaE(spl) region transcript mbeta0.769
EgfrEpidermal growth factor receptor0.759
slislit0.748
EcREcdysone receptor0.724
Nrx-IVNeurexin IV0.721
NetBNetrin-B0.707
Fas2Fasciclin 20.697
bynbrachyenteron0.673
nejnejire0.668
lealeak0.666
RalaRas-related protein0.650
fkhfork head0.636
drprdraper0.633
binbiniou0.633
snostrawberry notch0.610
aopanterior open0.609
HLHm5E(spl) region transcript m50.608
Wnt5Wnt oncogene analog 50.591
cicubitus interruptus0.589
betaTub60Dbeta-Tubulin at 60D0.585
snssticks and stones0.568
Rac1CG2248 gene product from transcript CG2248-RA0.565
brkbrinker0.564
Src42ASrc oncogene at 42A0.551
LanB1CG7123 gene product from transcript CG7123-RA0.548
shgshotgun0.540
HLHmdeltaE(spl) region transcript mdelta0.533
abd-Aabdominal A0.531
B52CG10851 gene product from transcript CG10851-RB0.527
roboroundabout0.523
zfh1Zn finger homeodomain 10.515
slp1sloppy paired 10.512
babobaboon0.508
HHairless0.508
dppdecapentaplegic0.505
thsthisbe0.494
NcNedd2-like caspase0.476
inscinscuteable0.466
Six4CG3871 gene product from transcript CG3871-RA0.458
eastenhanced adult sensory threshold0.455
gcmglial cells missing0.454
AlkCG8250 gene product from transcript CG8250-RA0.439
Rho1CG8416 gene product from transcript CG8416-RB0.438
jingCG9397 gene product from transcript CG9397-RI0.435
armarmadillo0.433
LysELysozyme E0.428
HLHm7E(spl) region transcript m70.426
lolalongitudinals lacking0.415
vvlventral veins lacking0.415
vndventral nervous system defective0.402
pzgputzig0.389
dlpdally-like0.388
slouslouch0.381
unc-5CG8166 gene product from transcript CG8166-RA0.379
edlETS-domain lacking0.374
pucpuckered0.370
garzgartenzwerg0.369
mammastermind0.367
htlheartless0.362
fngfringe0.356
MED24Mediator complex subunit 240.355
SasSialic acid phosphate synthase0.351
srpserpent0.349
Nf-YCNuclear factor Y-box C0.348
Cdc42CG12530 gene product from transcript CG12530-RA0.346
CG4822CG4822 gene product from transcript CG4822-RB0.334
JIL-1CG6297 gene product from transcript CG6297-RA0.332
LysBLysozyme B0.332
Gprk2G protein-coupled receptor kinase 20.318
CG14005CG14005 gene product from transcript CG14005-RA0.314
nkdnaked cuticle0.313
CG4328CG4328 gene product from transcript CG4328-RB0.311
Cad99CCG31009 gene product from transcript CG31009-RB0.307
otkoff-track0.307
CatCatalase0.307
SoxNSoxNeuro0.305
jumujumeau0.304
Atg1Autophagy-specific gene 10.304
LIMK1LIM-kinase10.297
lbeladybird early0.288
CG14869CG14869 gene product from transcript CG14869-RB0.283
eveeven skipped0.281
jarjaguar0.279
plexBplexin B0.276
HLHmgammaE(spl) region transcript mgamma0.275
lblladybird late0.273
gsbgooseberry0.272
bskbasket0.269
osoutstretched0.266
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.886
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.365
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.237
FGFR2fibroblast growth factor receptor 20.174
FYNFYN oncogene related to SRC, FGR, YES0.154
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.154
EGFRepidermal growth factor receptor0.123
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.102
FLNAfilamin A, alpha0.081
FN1fibronectin 10.076
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.055
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.053
FGF1fibroblast growth factor 1 (acidic)0.050
FGFR1fibroblast growth factor receptor 10.046
NRP1neuropilin 10.043
PLECplectin0.041
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.039
JUPjunction plakoglobin0.034
HSPG2heparan sulfate proteoglycan 20.034
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.033
PTPRJprotein tyrosine phosphatase, receptor type, J0.033
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.030
VEGFAvascular endothelial growth factor A0.029
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.024
PSEN1presenilin 10.020
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.019
LCKlymphocyte-specific protein tyrosine kinase0.017
PDIA3protein disulfide isomerase family A, member 30.016
DVL3dishevelled, dsh homolog 3 (Drosophila)0.016
ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)0.015
THBS1thrombospondin 10.015
NOTCH3notch 30.014
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.014
SYKspleen tyrosine kinase0.014
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.013
ENGendoglin0.013
PTPRCprotein tyrosine phosphatase, receptor type, C0.012
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.012
LAMB1laminin, beta 10.012
MEOX2mesenchyme homeobox 20.012
FHL2four and a half LIM domains 20.011
NOTCH1notch 10.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 20.996
Lamc1laminin, gamma 10.945
Trp63transformation related protein 630.942
Robo1roundabout homolog 1 (Drosophila)0.938
Vegfavascular endothelial growth factor A0.912
Dvl2dishevelled 2, dsh homolog (Drosophila)0.909
Ntn1netrin 10.906
Pax3paired box gene 30.900
Hspg2perlecan (heparan sulfate proteoglycan 2)0.898
Gli3GLI-Kruppel family member GLI30.851
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.849
Vangl2vang-like 2 (van gogh, Drosophila)0.843
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.776
Plcg1phospholipase C, gamma 10.772
Ptgs2prostaglandin-endoperoxide synthase 20.740
Mmp9matrix metallopeptidase 90.739
Notch2Notch gene homolog 2 (Drosophila)0.730
Nognoggin0.724
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.715
Nrp1neuropilin 10.706
Ptk2PTK2 protein tyrosine kinase 20.691
Ddr2discoidin domain receptor family, member 20.691
Egfrepidermal growth factor receptor0.685
Csf1colony stimulating factor 1 (macrophage)0.673
Sox2SRY-box containing gene 20.657
Itgb3integrin beta 30.657
Bmp4bone morphogenetic protein 40.651
Shhsonic hedgehog0.644
Tcf21transcription factor 210.628
Ptk7PTK7 protein tyrosine kinase 70.620
Fgf10fibroblast growth factor 100.617
Plauplasminogen activator, urokinase0.608
Pcsk5proprotein convertase subtilisin/kexin type 50.607
Lama5laminin, alpha 50.596
Vangl1vang-like 1 (van gogh, Drosophila)0.594
Ctnnb1catenin (cadherin associated protein), beta 10.587
Itga3integrin alpha 30.567
Gli2GLI-Kruppel family member GLI20.512
Tbx2T-box 20.496
Slit2slit homolog 2 (Drosophila)0.495
Dmddystrophin, muscular dystrophy0.486
Kdrkinase insert domain protein receptor0.485
Flt4FMS-like tyrosine kinase 40.432
Rargretinoic acid receptor, gamma0.429
Itgb1integrin beta 1 (fibronectin receptor beta)0.401
Tbx3T-box 30.394
Arandrogen receptor0.392
EdaraddEDAR (ectodysplasin-A receptor)-associated death domain0.391
Il10interleukin 100.390
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.386
Slit3slit homolog 3 (Drosophila)0.378
Il4interleukin 40.371
Gdnfglial cell line derived neurotrophic factor0.355
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.345
Tgfb2transforming growth factor, beta 20.335
SrcRous sarcoma oncogene0.333
Alx4aristaless-like homeobox 40.332
Lamb1laminin B10.330
Nos2nitric oxide synthase 2, inducible0.328
Ighimmunoglobulin heavy chain complex0.327
Fgfr4fibroblast growth factor receptor 40.313
Retret proto-oncogene0.307
Dll1delta-like 1 (Drosophila)0.299
Notch1Notch gene homolog 1 (Drosophila)0.297
Ikzf1IKAROS family zinc finger 10.291
Sema3csema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C0.289
Fgfr1fibroblast growth factor receptor 10.285
Hoxa13homeobox A130.284
Fgf7fibroblast growth factor 70.284
Ror1receptor tyrosine kinase-like orphan receptor 10.265
Tlx3T-cell leukemia, homeobox 30.262
Rararetinoic acid receptor, alpha0.257
Tnftumor necrosis factor0.256
Smad6MAD homolog 6 (Drosophila)0.252
Lhx1LIM homeobox protein 10.244
Col4a2collagen, type IV, alpha 20.243
Nos3nitric oxide synthase 3, endothelial cell0.242
Il6stinterleukin 6 signal transducer0.240
Jag1jagged 10.238
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.235
Hoxa11homeobox A110.234
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.231
Foxa2forkhead box A20.227
Edarectodysplasin-A receptor0.222
Gata4GATA binding protein 40.221
Gab1growth factor receptor bound protein 2-associated protein 10.218
Zeb1zinc finger E-box binding homeobox 10.216
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.211
RgnefRho-guanine nucleotide exchange factor0.210
Ror2receptor tyrosine kinase-like orphan receptor 20.203
Epha4Eph receptor A40.199
Lama1laminin, alpha 10.195
Dccdeleted in colorectal carcinoma0.194
Dvl1dishevelled, dsh homolog 1 (Drosophila)0.192
Trp73transformation related protein 730.191
Lama3laminin, alpha 30.187
Hoxd13homeobox D130.184
Lama4laminin, alpha 40.176
Dvl3dishevelled 3, dsh homolog (Drosophila)0.175
Meox2mesenchyme homeobox 20.172
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism