The network for 'proteasomal protein catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

proteasomal protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.

NameDescriptionProbabilityFunc Analog Organism
Psma5proteasome (prosome, macropain) subunit, alpha type 50.964
Psma3proteasome (prosome, macropain) subunit, alpha type 30.804
Psmb3proteasome (prosome, macropain) subunit, beta type 30.655
Psma2proteasome (prosome, macropain) subunit, alpha type 20.571
Psma4proteasome (prosome, macropain) subunit, alpha type 40.536
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.528
Psmb2proteasome (prosome, macropain) subunit, beta type 20.475
Psmb6proteasome (prosome, macropain) subunit, beta type 60.450
Psma7proteasome (prosome, macropain) subunit, alpha type 70.447
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.252
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.167
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.154
Psmb4proteasome (prosome, macropain) subunit, beta type 40.143
Hsp90b1heat shock protein 90, beta, member 10.127
Psmb1proteasome (prosome, macropain) subunit, beta type 10.106
Ubxn1UBX domain protein 10.098
Hprt1hypoxanthine phosphoribosyltransferase 10.086
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.086
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.081
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.081
Eef2eukaryotic translation elongation factor 20.055
Pompproteasome maturation protein0.053
Manfmesencephalic astrocyte-derived neurotrophic factor0.052
Psmd8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.051
Pdia4protein disulfide isomerase family A, member 40.050
Psmb7proteasome (prosome, macropain) subunit, beta type 70.049
Phaxphosphorylated adaptor for RNA export0.046
Psmb5proteasome (prosome, macropain) subunit, beta type 50.045
CnbpCCHC-type zinc finger, nucleic acid binding protein0.044
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.041
Creld2cysteine-rich with EGF-like domains 20.037
Serp1stress-associated endoplasmic reticulum protein 10.035
Traf4af1TRAF4 associated factor 10.033
Psme2proteasome (prosome, macropain) activator subunit 20.031
Rbbp7retinoblastoma binding protein 70.031
Cand1cullin-associated and neddylation-dissociated 10.030
Dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.030
Prdx1peroxiredoxin 10.029
Sumo1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.028
Dnajb11DnaJ (Hsp40) homolog, subfamily B, member 110.027
Spag5sperm associated antigen 50.027
Mapre1microtubule-associated protein, RP/EB family, member 10.027
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.025
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.024
Rpn2ribophorin II0.024
Ufd1lubiquitin fusion degradation 1 like (yeast)0.023
Psmb10proteasome (prosome, macropain) subunit, beta type 100.022
Ccnb1cyclin B10.022
Cenpicentromere protein I0.022
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.022
Eif5aeukaryotic translation initiation factor 5A0.021
Psma1proteasome (prosome, macropain) subunit, alpha type 10.021
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.021
Ube2iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.021
Txnl1thioredoxin-like 10.020
Pdia6protein disulfide isomerase family A, member 60.020
Rpn1ribophorin I0.019
Syngr2synaptogyrin 20.019
Myo1cmyosin IC0.018
Higd1aHIG1 hypoxia inducible domain family, member 1A0.017
Ptges3prostaglandin E synthase 3 (cytosolic)0.017
Slc35b1solute carrier family 35, member B10.017
Foxm1forkhead box M10.016
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.016
Top2atopoisomerase (DNA) II alpha0.016
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.016
Mgat2mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase0.016
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.015
Lbrlamin B receptor0.014
Hyou1hypoxia up-regulated 10.014
Arf1ADP-ribosylation factor 10.014
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.014
Gmfbglia maturation factor, beta0.013
Zfand5zinc finger, AN1-type domain 50.013
Dnpepaspartyl aminopeptidase0.013
Psmd7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.012
Lamp2lysosomal-associated membrane protein 20.012
Timm23translocase of inner mitochondrial membrane 23 homolog (yeast)0.012
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.012
LOC100310874antisense RNA overlapping MCH0.012
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.012
Rab11aRAB11a, member RAS oncogene family0.011
Hspa5heat shock protein 50.011
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.011
Usp14ubiquitin specific peptidase 140.011
Nsfl1cNSFL1 (p97) cofactor (p47)0.011
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.011
Rgs19regulator of G-protein signaling 190.011
Axin1axin 10.010
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.010
Lrrc59leucine rich repeat containing 590.010
Dnajc5DnaJ (Hsp40) homolog, subfamily C, member 50.010
Akt1s1AKT1 substrate 1 (proline-rich)0.010
Myo1bmyosin Ib0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
rpn-7Protein RPN-70.492
rpn-12Protein RPN-120.414
pas-4Protein PAS-40.407
pas-2Protein PAS-20.350
pbs-3Protein PBS-30.333
rpt-5Protein RPT-50.319
rpn-3Protein RPN-30.300
npl-4.2Protein NPL-4.20.293
rpt-2Protein RPT-20.288
rpt-3Protein RPT-30.287
pbs-5Protein PBS-50.270
pbs-2Protein PBS-20.188
cul-1Protein CUL-10.185
rpn-2Protein RPN-20.138
rpn-6.1Protein RPN-6.10.131
imb-2Protein IMB-20.124
pbs-1Protein PBS-10.112
pas-1Protein PAS-10.102
daf-21Protein DAF-210.101
mig-5Protein MIG-50.093
F25B3.6Protein F25B3.60.091
CELE_K08F4.1Protein K08F4.10.090
bub-1Protein BUB-10.090
app-1Protein APP-10.088
rpt-4Protein RPT-40.084
syx-17Protein SYX-170.080
npl-4.1Protein NPL-4.10.075
rpn-5Protein RPN-50.072
pbs-7Protein PBS-70.070
rod-1Protein ROD-10.070
egl-18Protein EGL-180.069
pbs-6Protein PBS-60.066
F37A4.1Protein F37A4.10.063
R11A8.7Protein R11A8.70.062
pbs-4Protein PBS-40.062
tba-2Protein TBA-20.061
zyg-9Protein ZYG-90.060
taf-5Protein TAF-50.059
gpr-2Protein GPR-20.059
atx-3Protein ATX-30.058
pcn-1Protein PCN-10.056
ebp-2Protein EBP-20.054
rpn-1Protein RPN-10.053
ima-2Protein IMA-20.052
hgrs-1Protein HGRS-10.052
dnj-12Protein DNJ-120.051
his-42Protein HIS-420.049
rad-26Protein RAD-260.045
stam-1Protein STAM-10.045
csn-3Protein CSN-30.044
C49H3.9Protein C49H3.90.044
zen-4Protein ZEN-40.043
ima-3Protein IMA-30.040
mdf-2Protein MDF-20.038
K08E3.5Protein K08E3.50.036
rpn-9Protein RPN-90.035
CELE_F52C6.12Protein F52C6.120.034
pas-6Protein PAS-60.034
dsh-2Protein DSH-20.033
K02B2.1Protein K02B2.10.031
dpy-30Protein DPY-300.031
ztf-7Protein ZTF-70.030
Y71H2AM.20Protein Y71H2AM.200.029
B0041.5Protein B0041.50.028
D1081.8Protein D1081.80.028
klp-16Protein KLP-160.027
ubq-1Protein UBQ-10.027
cdc-48.2Protein CDC-48.20.026
ran-1Protein RAN-10.026
pas-3Protein PAS-30.026
pas-7Protein PAS-70.026
pap-1Protein PAP-10.026
C35A5.8Protein C35A5.80.025
prp-21Protein PRP-210.025
W09D10.1Protein W09D10.10.025
xbp-1Protein XBP-10.025
sel-12Protein SEL-120.025
F08B4.7Protein F08B4.70.024
asb-1Protein ASB-10.024
mom-2Protein MOM-20.024
pup-2Protein PUP-20.024
emo-1Protein EMO-10.024
his-6Protein HIS-60.024
rsp-7Protein RSP-70.023
lsy-22Protein LSY-220.023
ZC434.8Protein ZC434.80.023
par-5Protein PAR-50.023
F46F11.6Protein F46F11.60.022
dlc-1Protein DLC-10.022
rpt-1Protein RPT-10.022
CELE_B0334.5Protein B0334.50.022
csnk-1Protein CSNK-10.022
tbb-2Protein TBB-20.022
hsp-1Protein HSP-10.022
T22C1.1Protein T22C1.10.021
Y47D3A.29Protein Y47D3A.290.021
pri-2Protein PRI-20.021
C23H3.3Protein C23H3.30.021
CELE_F20D1.3Protein F20D1.30.021
swsn-6Protein SWSN-60.021
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.827
psma6aproteasome (prosome, macropain) subunit, alpha type, 6a0.772
psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.760
psma4proteasome (prosome, macropain) subunit, alpha type, 40.660
psmb1proteasome (prosome, macropain) subunit, beta type, 10.654
psma8proteasome (prosome, macropain) subunit, alpha type, 80.635
psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.634
psmb4proteasome (prosome, macropain) subunit, beta type, 40.629
psmb7proteasome (prosome, macropain) subunit, beta type, 70.596
psmb3proteasome (prosome, macropain) subunit, beta type, 30.586
hspa4bheat shock protein 4b0.554
hspa5heat shock protein 50.526
psma1proteasome (prosome, macropain) subunit, alpha type, 10.518
psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.515
tacc3transforming, acidic coiled-coil containing protein 30.512
psmb5proteasome (prosome, macropain) subunit, beta type, 50.476
adrm1badhesion regulating molecule 1b0.458
psmb2proteasome (prosome, macropain) subunit, beta type, 20.456
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.455
psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.454
psmc1bproteasome (prosome, macropain) 26S subunit, ATPase, 1b0.428
psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.420
psma2proteasome (prosome, macropain) subunit, alpha type, 20.370
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.368
kif23kinesin family member 230.350
bnip3lbBCL2/adenovirus E1B interacting protein 3-like b0.337
psmc3proteasome (prosome, macropain) 26S subunit, ATPase, 30.328
ck2bcasein kinase 2 beta0.326
dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.322
usp5ubiquitin specific protease 50.321
ccnb1cyclin B10.314
maxmyc-associated factor X0.309
smad9MAD homolog 9 (Drosophila)0.295
chukconserved helix-loop-helix ubiquitous kinase0.286
psmc1aproteasome (prosome, macropain) 26S subunit, ATPase, 1a0.264
syvn1synovial apoptosis inhibitor 1, synoviolin0.264
nup93nucleoporin 930.264
kpna4karyopherin alpha 4 (importin alpha 3)0.253
psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.240
hyou1hypoxia up-regulated 10.226
bsdc1BSD domain containing 10.215
eif1beukaryotic translation initiation factor 1B0.213
blmhbleomycin hydrolase0.213
ccna2cyclin A20.206
ythdf1YTH domain family, member 10.205
cdc20cell division cycle 20 homolog0.204
vcpvalosin containing protein0.204
rqcd1RCD1 required for cell differentiation1 homolog (S. pombe)0.196
psmb11proteasome (prosome, macropain) subunit, beta type, 110.183
fliiflightless I homolog (Drosophila)0.180
hist2h2lhistone 2, H2, like0.179
arpp19acAMP-regulated phosphoprotein 19a0.176
psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.171
btg2B-cell translocation gene 20.171
ciapin1cytokine induced apoptosis inhibitor 10.169
aurkbaurora kinase B0.166
cdca8cell division cycle associated 80.165
mobkl3MOB1, Mps One Binder kinase activator-like 3 (yeast)0.165
mxamyxovirus (influenza) resistance A0.163
hnrpklheterogeneous nuclear ribonucleoprotein K, like0.163
ywhabatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a0.163
gmnngeminin, DNA replication inhibitor0.160
ikIK cytokine0.159
fxr2fragile X mental retardation, autosomal homolog 20.158
ypel3yippee-like 30.158
psmd4bproteasome (prosome, macropain) 26S subunit, non-ATPase, 4b0.154
psma6bproteasome (prosome, macropain) subunit, alpha type, 6b0.154
skp2S-phase kinase-associated protein 2 (p45)0.153
psmb6proteasome (prosome, macropain) subunit, beta type, 60.153
sirt1sirtuin (silent mating type information regulation 2 homolog) 10.149
tfap2atranscription factor AP-2 alpha0.149
ddx42DEAD (Asp-Glu-Ala-Asp) box polypeptide 420.147
ube2g2ubiquitin-conjugating enzyme E2G 20.147
polr2bpolymerase (RNA) II (DNA directed) polypeptide B0.144
cand1cullin-associated and neddylation-dissociated 10.142
prkrirprotein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)0.141
psmb8proteasome (prosome, macropain) subunit, beta type, 80.140
tp53tumor protein p530.139
gspt1lG1 to S phase transition 1, like0.135
tfpi2tissue factor pathway inhibitor 20.135
dusp1dual specificity phosphatase 10.133
dvl3dishevelled, dsh homolog 3 (Drosophila)0.131
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.130
cdh1cadherin 1, epithelial0.128
klhdc10kelch domain containing 100.128
tram1translocating chain-associating membrane protein 10.127
baxabcl2-associated X protein, a0.127
gdi2GDP dissociation inhibitor 20.127
rtkn2rhotekin 20.126
bc2putative breast adenocarcinoma marker0.123
cdt1chromatin licensing and DNA replication factor 10.122
psmb10proteasome (prosome, macropain) subunit, beta type, 100.122
psmd11aproteasome (prosome, macropain) 216S subunit, non-ATPase, 11a0.121
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
tefutelomere fusion0.918
Ras85DRas oncogene at 85D0.841
Prosbeta2Proteasome beta2 subunit0.829
Mov34CG3416 gene product from transcript CG3416-RA0.684
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.670
Rpt3CG16916 gene product from transcript CG16916-RA0.642
Rpn9CG10230 gene product from transcript CG10230-RB0.606
Rpt4CG3455 gene product from transcript CG3455-RA0.564
Rpt1CG1341 gene product from transcript CG1341-RA0.502
Prosbeta1Proteasome beta1 subunit0.478
Pros29Proteasome 29kD subunit0.466
CycB3Cyclin B30.428
CG13349CG13349 gene product from transcript CG13349-RA0.415
UbcD2Ubiquitin conjugating enzyme 20.405
Pros54Proteasome 54kD subunit0.384
Rpn2CG11888 gene product from transcript CG11888-RA0.378
IncenpInner centromere protein0.336
Rpn11CG18174 gene product from transcript CG18174-RA0.330
Prosalpha7Proteasome alpha7 subunit0.327
Tbp-1Tat-binding protein-10.320
Rpn1CG7762 gene product from transcript CG7762-RA0.311
Stat92ESignal-transducer and activator of transcription protein at 92E0.300
Pros45CG1489 gene product from transcript CG1489-RA0.298
Pros28.1Proteasome 28kD subunit 10.287
dosdaughter of sevenless0.280
Rab11Rab-protein 110.270
slmbsupernumerary limbs0.254
Prosbeta3Proteasome beta3 subunit0.243
Prosalpha5Proteasome alpha5 subunit0.239
Rpn6Proteasome p44.5 subunit0.238
swmsecond mitotic wave missing0.226
ncdnon-claret disjunctional0.225
Rpn7CG5378 gene product from transcript CG5378-RA0.219
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.218
CycBCyclin B0.210
Prosbeta5Proteasome beta5 subunit0.202
Vap-33-1CG5014 gene product from transcript CG5014-RB0.196
Top1Topoisomerase 10.192
CG12321CG12321 gene product from transcript CG12321-RA0.187
gemininCG3183 gene product from transcript CG3183-RA0.178
CycDCyclin D0.176
StimStromal interaction molecule0.169
SaraSmad anchor for receptor activation0.165
CSN4COP9 complex homolog subunit 40.165
Tab2TAK1-associated binding protein 20.162
CG6961CG6961 gene product from transcript CG6961-RA0.160
IswiImitation SWI0.160
Prosbeta7Proteasome beta7 subunit0.157
dcodiscs overgrown0.149
CG5555CG5555 gene product from transcript CG5555-RA0.146
Pros35Proteasome 35kD subunit0.144
Tip60CG6121 gene product from transcript CG6121-RA0.140
Rpd3CG7471 gene product from transcript CG7471-RA0.136
bratbrain tumor0.133
Rpn5CG1100 gene product from transcript CG1100-RA0.132
pr-set7CG3307 gene product from transcript CG3307-RC0.125
Cdc37CG12019 gene product from transcript CG12019-RA0.123
Mcm10Sensitized chromosome inheritance modifier 190.120
p53CG33336 gene product from transcript CG33336-RB0.118
dupdouble parked0.118
piepineapple eye0.111
CG4673CG4673 gene product from transcript CG4673-RB0.111
p47CG11139 gene product from transcript CG11139-RA0.110
RYBPRing and YY1 Binding Protein0.104
Cap-GCG34438 gene product from transcript CG34438-RF0.101
CanB2Calcineurin B20.100
CG32581CG32581 gene product from transcript CG32581-RB0.100
CG17331CG17331 gene product from transcript CG17331-RA0.100
RASSF8CG5053 gene product from transcript CG5053-RA0.098
SAKSak kinase0.096
CG9772CG9772 gene product from transcript CG9772-RB0.096
CG8290CG8290 gene product from transcript CG8290-RA0.093
Rpn3Regulatory particle non-ATPase 30.093
Nipped-ACG33554 gene product from transcript CG33554-RE0.093
Akt1CG4006 gene product from transcript CG4006-RA0.092
HerpHomocysteine-induced endoplasmic reticulum protein0.092
Fcp1CG12252 gene product from transcript CG12252-RA0.091
CG8974CG8974 gene product from transcript CG8974-RD0.087
CycECyclin E0.087
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PSMA2proteasome (prosome, macropain) subunit, alpha type, 21.000
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 41.000
CUL1cullin 11.000
UBCubiquitin C1.000
PSMA6proteasome (prosome, macropain) subunit, alpha type, 61.000
TP53tumor protein p531.000
SKP1S-phase kinase-associated protein 10.999
VCPvalosin containing protein0.999
CUL3cullin 30.999
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.998
RNF11ring finger protein 110.997
UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)0.995
PSMA1proteasome (prosome, macropain) subunit, alpha type, 10.994
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.993
CDC20cell division cycle 20 homolog (S. cerevisiae)0.989
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.989
PSMA5proteasome (prosome, macropain) subunit, alpha type, 50.988
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.988
MDM2Mdm2 p53 binding protein homolog (mouse)0.987
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.987
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.985
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.984
UBQLN1ubiquilin 10.981
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.980
RBX1ring-box 1, E3 ubiquitin protein ligase0.980
PSMA3proteasome (prosome, macropain) subunit, alpha type, 30.977
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.976
BTRCbeta-transducin repeat containing0.975
PSMB7proteasome (prosome, macropain) subunit, beta type, 70.974
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.973
SKP2S-phase kinase-associated protein 2 (p45)0.972
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.967
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.963
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.957
PSMB3proteasome (prosome, macropain) subunit, beta type, 30.954
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.954
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.952
CDK2cyclin-dependent kinase 20.950
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.948
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.938
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.933
PSMB1proteasome (prosome, macropain) subunit, beta type, 10.932
PLK1polo-like kinase 10.931
UCHL5ubiquitin carboxyl-terminal hydrolase L50.927
GSK3Bglycogen synthase kinase 3 beta0.923
XIAPX-linked inhibitor of apoptosis0.923
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.920
SMAD2SMAD family member 20.920
TCEB1transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)0.918
YY1YY1 transcription factor0.908
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.900
OTUB1OTU domain, ubiquitin aldehyde binding 10.899
PSMB6proteasome (prosome, macropain) subunit, beta type, 60.896
CDC27cell division cycle 27 homolog (S. cerevisiae)0.895
CCNB1cyclin B10.894
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.893
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.890
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.886
PSME3proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)0.882
PSMB2proteasome (prosome, macropain) subunit, beta type, 20.881
DVL3dishevelled, dsh homolog 3 (Drosophila)0.878
MDM4Mdm4 p53 binding protein homolog (mouse)0.852
PSMB4proteasome (prosome, macropain) subunit, beta type, 40.842
SMAD4SMAD family member 40.837
ATXN3ataxin 30.837
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.833
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.830
POMPproteasome maturation protein0.825
SQSTM1sequestosome 10.809
ANAPC7anaphase promoting complex subunit 70.807
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.797
HUWE1HECT, UBA and WWE domain containing 10.796
RB1retinoblastoma 10.791
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.785
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.785
CCNA2cyclin A20.775
PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.770
RFWD2ring finger and WD repeat domain 20.763
FZR1fizzy/cell division cycle 20 related 1 (Drosophila)0.748
SMURF2SMAD specific E3 ubiquitin protein ligase 20.743
UFD1Lubiquitin fusion degradation 1 like (yeast)0.739
CKS1BCDC28 protein kinase regulatory subunit 1B0.730
UBA1ubiquitin-like modifier activating enzyme 10.721
FBXW11F-box and WD repeat domain containing 110.719
RAD23BRAD23 homolog B (S. cerevisiae)0.706
AKT1v-akt murine thymoma viral oncogene homolog 10.705
CREBBPCREB binding protein0.702
SYVN1synovial apoptosis inhibitor 1, synoviolin0.702
ADRM1adhesion regulating molecule 10.699
HDAC1histone deacetylase 10.698
FBXW2F-box and WD repeat domain containing 20.682
BIRC2baculoviral IAP repeat containing 20.671
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.656
FBXO5F-box protein 50.646
PSME2proteasome (prosome, macropain) activator subunit 2 (PA28 beta)0.639
BRCA1breast cancer 1, early onset0.637
SMAD1SMAD family member 10.632
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.628
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.627
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.623
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.999
Ctnnb1catenin (cadherin associated protein), beta 10.997
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.983
Psma2proteasome (prosome, macropain) subunit, alpha type 20.975
Mdm2transformed mouse 3T3 cell double minute 20.963
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.954
Ptenphosphatase and tensin homolog0.936
Psma5proteasome (prosome, macropain) subunit, alpha type 50.935
Psmb7proteasome (prosome, macropain) subunit, beta type 70.920
Psmb6proteasome (prosome, macropain) subunit, beta type 60.917
Psma7proteasome (prosome, macropain) subunit, alpha type 70.913
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.904
Psma6proteasome (prosome, macropain) subunit, alpha type 60.904
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.868
Vhlvon Hippel-Lindau tumor suppressor0.868
Psma1proteasome (prosome, macropain) subunit, alpha type 10.844
Per1period homolog 1 (Drosophila)0.844
Axin1axin 10.822
Vcpvalosin containing protein0.799
Clockcircadian locomotor output cycles kaput0.797
Cdk1cyclin-dependent kinase 10.786
Stat3signal transducer and activator of transcription 30.772
Usp9xubiquitin specific peptidase 9, X chromosome0.768
Per2period homolog 2 (Drosophila)0.756
Ccnb1cyclin B10.751
Smurf2SMAD specific E3 ubiquitin protein ligase 20.748
Mbd3methyl-CpG binding domain protein 30.737
Psmb4proteasome (prosome, macropain) subunit, beta type 40.726
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.722
Cops2COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)0.715
Gsk3bglycogen synthase kinase 3 beta0.702
Adrm1adhesion regulating molecule 10.701
Skp1aS-phase kinase-associated protein 1A0.696
Thrathyroid hormone receptor alpha0.690
Notch2Notch gene homolog 2 (Drosophila)0.689
Spcs2signal peptidase complex subunit 2 homolog (S. cerevisiae)0.628
Cul3cullin 30.627
Ccne1cyclin E10.614
Psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.607
Arrb2arrestin, beta 20.605
Psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.605
Brca1breast cancer 10.603
Ngly1N-glycanase 10.576
Psma3proteasome (prosome, macropain) subunit, alpha type 30.555
Fzr1fizzy/cell division cycle 20 related 1 (Drosophila)0.548
Bcl2B-cell leukemia/lymphoma 20.542
Cops5COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)0.530
Kpna1karyopherin (importin) alpha 10.530
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.527
Pax8paired box gene 80.521
Mdm4transformed mouse 3T3 cell double minute 40.507
Psmd14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.504
Dyrk1adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a0.503
Rnf2ring finger protein 20.490
Nploc4nuclear protein localization 4 homolog (S. cerevisiae)0.487
Atf4activating transcription factor 40.486
Birc5baculoviral IAP repeat-containing 50.483
Csnk1g2casein kinase 1, gamma 20.476
Pias2protein inhibitor of activated STAT 20.475
Psmb3proteasome (prosome, macropain) subunit, beta type 30.469
Smad7MAD homolog 7 (Drosophila)0.466
Ccnb2cyclin B20.461
Pompproteasome maturation protein0.451
Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.447
Sox9SRY-box containing gene 90.445
Psmc5protease (prosome, macropain) 26S subunit, ATPase 50.445
Mlf2myeloid leukemia factor 20.441
Kpna3karyopherin (importin) alpha 30.440
Rnf111ring finger 1110.433
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)0.432
Hif1ahypoxia inducible factor 1, alpha subunit0.429
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.427
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.424
Hsf1heat shock factor 10.408
Cdca8cell division cycle associated 80.405
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.403
Fgfr1fibroblast growth factor receptor 10.401
Agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 30.385
Aampangio-associated migratory protein0.384
Gnb2guanine nucleotide binding protein (G protein), beta 20.377
Cry1cryptochrome 1 (photolyase-like)0.368
Ccna2cyclin A20.356
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.354
Rarbretinoic acid receptor, beta0.354
Psmb5proteasome (prosome, macropain) subunit, beta type 50.353
Notch1Notch gene homolog 1 (Drosophila)0.351
Bmi1Bmi1 polycomb ring finger oncogene0.343
Mllt1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.330
Yap1yes-associated protein 10.311
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.305
Gclmglutamate-cysteine ligase, modifier subunit0.305
Ring1ring finger protein 10.305
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.303
Igf1rinsulin-like growth factor I receptor0.295
Prc1protein regulator of cytokinesis 10.294
Aurkaaurora kinase A0.287
Cdk2cyclin-dependent kinase 20.287
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
YLR352Whypothetical protein0.390
YNL155Whypothetical protein0.372