The network for 'purine nucleotide biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

purine nucleotide biosynthetic process

The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

NameDescriptionProbabilityFunc Analog Organism
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.879
Atp5bATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.730
Slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.649
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.570
Fgf14fibroblast growth factor 140.483
Aldoaaldolase A, fructose-bisphosphate0.481
Grin3aglutamate receptor, ionotropic, N-methyl-D-aspartate 3A0.456
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.379
Adora1adenosine A1 receptor0.375
Slc8a2solute carrier family 8 (sodium/calcium exchanger), member 20.374
Ctsjcathepsin J0.367
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.337
Galr3galanin receptor 30.333
Adora2aadenosine A2a receptor0.309
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.305
Cox4i1cytochrome c oxidase subunit IV isoform 10.293
Scn10asodium channel, voltage-gated, type X, alpha subunit0.264
Notch3Notch homolog 3 (Drosophila)0.262
Hspd1heat shock protein 1 (chaperonin)0.260
Olr416olfactory receptor 4160.259
Mdh1malate dehydrogenase 1, NAD (soluble)0.226
Ncanneurocan0.223
Hrh3histamine receptor H30.212
Nfascneurofascin0.203
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.188
LOC100361879ATP synthase subunit epsilon, mitochondrial-like0.188
Cckarcholecystokinin A receptor0.179
Cela2achymotrypsin-like elastase family, member 2A0.179
Slc18a3solute carrier family 18 (vesicular acetylcholine), member 30.175
Syt7synaptotagmin VII0.175
Clstn3calsyntenin 30.163
Gpr1G protein-coupled receptor 10.162
Slc16a8solute carrier family 16, member 8 (monocarboxylic acid transporter 3)0.161
Phkg1phosphorylase kinase, gamma 10.159
Hcrthypocretin0.159
Pecam1platelet/endothelial cell adhesion molecule 10.155
Prp15proline-rich protein 150.153
Adra2cadrenergic, alpha-2C-, receptor0.152
Glp1rglucagon-like peptide 1 receptor0.150
Ldhalactate dehydrogenase A0.147
Cntfrciliary neurotrophic factor receptor0.145
Cmklr1chemokine-like receptor 10.144
Cyc1cytochrome c-10.144
Epn2epsin 20.142
Scn4asodium channel, voltage-gated, type IV, alpha subunit0.142
Opn1swopsin 1 (cone pigments), short-wave-sensitive0.142
Calcacalcitonin-related polypeptide alpha0.141
Drd2dopamine receptor D20.138
Vipvasoactive intestinal peptide0.136
Prrx1paired related homeobox 10.135
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.135
Csf3colony stimulating factor 3 (granulocyte)0.135
Galr2galanin receptor 20.134
Calm1calmodulin 10.133
Agtr1aangiotensin II receptor, type 1a0.133
Cacng8calcium channel, voltage-dependent, gamma subunit 80.132
Odf4outer dense fiber of sperm tails 40.131
Vipr1vasoactive intestinal peptide receptor 10.130
Kcnb2potassium voltage gated channel, Shab-related subfamily, member 20.127
Chrna4cholinergic receptor, nicotinic, alpha 40.127
Egr4early growth response 40.127
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.127
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.125
Cxcr5chemokine (C-X-C motif) receptor 50.125
Irf7interferon regulatory factor 70.124
Cntn4contactin 40.124
Calcrlcalcitonin receptor-like0.122
Sstr5somatostatin receptor 50.121
Mc4rmelanocortin 4 receptor0.118
Slc6a7solute carrier family 6 (neurotransmitter transporter, L-proline), member 70.118
Tacr3tachykinin receptor 30.118
Glra1glycine receptor, alpha 10.116
Cdc34cell division cycle 34 homolog (S. cerevisiae)0.113
Chrna7cholinergic receptor, nicotinic, alpha 70.108
Ppp3cbprotein phosphatase 3, catalytic subunit, beta isoform0.108
Ifnb1interferon beta 1, fibroblast0.108
Cckbrcholecystokinin B receptor0.108
Kcnn3potassium intermediate/small conductance calcium-activated channel, subfamily N, member 30.107
Atp5g3ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)0.106
Tpi1triosephosphate isomerase 10.106
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.105
Cysscystatin S0.105
Ddndendrin0.104
Gcnt3glucosaminyl (N-acetyl) transferase 3, mucin type0.104
Lgals3bplectin, galactoside-binding, soluble, 3 binding protein0.103
Sctsecretin0.102
RabggtbRab geranylgeranyltransferase, beta subunit0.102
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.100
Aqp2aquaporin 2 (collecting duct)0.100
Kctd13potassium channel tetramerisation domain containing 130.098
Htr75-hydroxytryptamine (serotonin) receptor 70.097
Cmtm2aCKLF-like MARVEL transmembrane domain containing 2A0.097
Itgamintegrin, alpha M0.096
Gcm1glial cells missing homolog 1 (Drosophila)0.095
Gucy2dguanylate cyclase 2d0.095
Naaladl1N-acetylated alpha-linked acidic dipeptidase-like 10.094
RGD1306917similar to RIKEN cDNA 2900010M230.094
Cd38CD38 molecule0.093
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.093
Trim17tripartite motif-containing 170.092
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
LOC569642hypothetical protein LOC5696420.946
uts1urotensin 10.888
oxtloxytocin-like0.886
avplarginine vasopressin-like0.872
si:dkey-228g21.4si:dkey-228g21.40.723
mc2rmelanocortin 2 receptor0.714
adrb2aadrenergic receptor, beta 2a0.683
adra2badrenergic, alpha-2B-, receptor0.678
mc4rmelanocortin 4 receptor0.666
guca1cguanylate cyclase activator 1C0.571
drd3dopamine receptor D30.529
LOC100003330melanocortin-2 receptor accessory protein 2-like0.510
adrb1adrenergic receptor, beta 10.471
cyp11b2cytochrome P450, family 11, subfamily B, polypeptide 20.463
ndufa4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 40.460
adra2dbadrenergic, alpha-2D-, receptor b0.451
drd2bdopamine receptor D2b0.429
mstnbmyostatin b0.401
hmgb1ahigh-mobility group box 1a0.397
gmpsguanine monphosphate synthetase0.371
mc1rmelanocortin 1 receptor0.336
drd2adopamine receptor D2a0.330
esr2aestrogen receptor 2a0.324
ucn3lurocortin 3, like0.319
fshrfollicle stimulating hormone receptor0.295
th2tyrosine hydroxylase 20.270
grk7aG-protein-coupled receptor kinase 7a0.269
adra2cadrenergic, alpha-2C-, receptor0.234
nme2b.2non-metastatic cells 2b.2, protein (NM23B) expressed in0.227
ros1v-ros UR2 sarcoma virus oncogene homolog 1 (avian)0.223
gnrh2gonadotropin-releasing hormone 20.219
hcrthypocretin (orexin) neuropeptide precursor0.217
sst3somatostatin 30.208
adra2aadrenergic, alpha-2A-, receptor0.195
LOC555482tachykinin receptor 3-like0.176
terttelomerase reverse transcriptase0.171
gucy2fguanylate cyclase 2F, retinal0.159
adcyap1r1aadenylate cyclase activating polypeptide 1 receptor 1a0.151
eno1enolase 1, (alpha)0.149
mpp5bmembrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5b)0.146
rag1recombination activating gene 10.142
pnrc2proline-rich nuclear receptor coactivator 20.139
cldn2claudin 20.133
inka1ainduced in neural crest by AP2, 1a0.131
mchr1amelanin-concentrating hormone receptor 1a0.129
mchr1bmelanin-concentrating hormone receptor 1b0.128
wu:fv91b12wu:fv91b120.127
LOC559201similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3)0.127
opn1mw1opsin 1 (cone pigments), medium-wave-sensitive, 10.122
htr1aa5-hydroxytryptamine (serotonin) receptor 1A a0.122
eef2l2eukaryotic translation elongation factor 2, like 20.119
nlgn4aneuroligin 4a0.117
zgc:152873zgc:1528730.115
hk1hexokinase 10.114
gpr182G protein-coupled receptor 1820.114
si:ch211-209p5.2si:ch211-209p5.20.109
dbhdopamine beta hydroxylase0.108
mc5rbmelanocortin 5b receptor0.104
opn4lopsin 4, like0.103
pax7bpaired box gene 7b0.101
rab2aRAB2A, member RAS oncogene family0.095
chrnb3bcholinergic receptor, nicotinic, beta polypeptide 3b0.095
gc2guanylyl cyclase 20.092
hccsholocytochrome c synthase0.090
atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase0.088
gdf9growth differentiation factor 90.085
sox5SRY-box containing gene 50.083
crygs2crystallin, gamma S20.082
atp1b2aATPase, Na+/K+ transporting, beta 2a polypeptide0.080
slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.079
LOC563363cholesterol side-chain cleavage enzyme, mitochondrial-like0.079
hmga2high mobility group AT-hook 20.079
kiss1rbKISS1 receptor b0.078
sagaS-antigen; retina and pineal gland (arrestin) a0.077
guca1dguanylate cyclase activator 1d0.076
bsk146brain specific kinase 1460.075
lmo4bLIM domain only 4b0.073
vipr2vasoactive intestinal peptide receptor 20.072
si:dkey-24h22.4si:dkey-24h22.40.071
opn1lw1opsin 1 (cone pigments), long-wave-sensitive, 10.071
junjun proto-oncogene0.064
paqr8progestin and adipoQ receptor family member VIII0.063
valopavertebrate ancient long opsin a0.063
clockclock0.062
arfip2bADP-ribosylation factor interacting protein 2b0.059
nrlneural retina leucine zipper0.058
ctsbacathepsin B, a0.058
npy8brneuropeptide Y receptor Y8b0.058
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.058
cx55.5connexin 55.50.055
rtn1areticulon 1a0.055
pvalb4parvalbumin 40.055
hsd17b2hydroxysteroid (17-beta) dehydrogenase 20.054
LOC799612prolactin 20.054
calcrcalcitonin receptor0.053
LOC563328lysosome-associated membrane glycoprotein 1-like0.052
mc3rmelanocortin 3 receptor0.051
slc6a8solute carrier family 6 (neurotransmitter transporter, creatine), member 80.051
flj13639flj136390.050
nr2e3nuclear receptor subfamily 2, group E, member 30.049
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Nmdar1NMDA receptor 10.704
dncdunce0.641
AmphAmphiphysin0.244
TbhTyramine beta hydroxylase0.232
ShawShaker cognate w0.209
Pde8Phosphodiesterase 80.196
witwishful thinking0.173
Atf-2Activating transcription factor-20.171
CaMKIICalcium/calmodulin-dependent protein kinase II0.168
CG13253CG13253 gene product from transcript CG13253-RB0.144
CngCyclic-nucleotide-gated ion channel protein0.136
Gyc-89DbGuanylyl cyclase at 89Db0.127
CG34400CG34400 gene product from transcript CG34400-RD0.116
ade3adenosine 30.113
ade5CG3989 gene product from transcript CG3989-RA0.111
sloslowpoke0.105
Rya-r44FRyanodine receptor 44F0.102
OscpOligomycin sensitivity-conferring protein0.085
Eaat1Excitatory amino acid transporter 10.082
Pp2B-14DProtein phosphatase 2B at 14D0.075
smi35Asmell impaired 35A0.075
neuroliginCG13772 gene product from transcript CG13772-RA0.074
blwbellwether0.074
DskDrosulfakinin0.072
l(1)G0230lethal (1) G02300.071
timtimeless0.068
Gyc-89DaGuanylyl cyclase at 89Da0.067
ActbetaActivin-beta0.066
CG11876CG11876 gene product from transcript CG11876-RA0.065
G-salpha60AG protein salpha 60A0.064
Pdp1PAR-domain protein 10.063
Act5CActin 5C0.062
klgklingon0.054
5-HT1ASerotonin receptor 1A0.053
crycryptochrome0.053
Mst57DbMale-specific RNA 57Db0.050
CG42629CG42629 gene product from transcript CG42629-RB0.050
ATPsyn-gammaATP synthase-gamma chain0.049
AconAconitase0.049
CG11089CG11089 gene product from transcript CG11089-RD0.048
jebjelly belly0.047
mttmangetout0.046
5-HT1BSerotonin receptor 1B0.046
PgkPhosphoglycerate kinase0.045
CanA1Calcineurin A10.045
IhI[[h]] channel0.044
amonamontillado0.043
InRInsulin-like receptor0.042
ninaBneither inactivation nor afterpotential B0.042
CG11255CG11255 gene product from transcript CG11255-RA0.040
Rtnl1CG33113 gene product from transcript CG33113-RF0.038
OatOrnithine aminotransferase precursor0.036
Eaat2Excitatory amino acid transporter 20.036
CG14686CG14686 gene product from transcript CG14686-RA0.036
tauCG31057 gene product from transcript CG31057-RA0.036
Gr64eGustatory receptor 64e0.035
EnoEnolase0.034
Ank2Ankyrin 20.034
highikaru genki0.034
5-HT7Serotonin receptor 70.034
porinCG6647 gene product from transcript CG6647-RA0.033
CG16778CG16778 gene product from transcript CG16778-RA0.033
dprdefective proboscis extension response0.032
nAcRalpha-30Dnicotinic Acetylcholine Receptor alpha 30D0.032
Eip63F-1Ecdysone-induced protein 63F 10.031
CG3011CG3011 gene product from transcript CG3011-RA0.031
oa2octopamine receptor 20.030
Ten-aTenascin accessory0.029
Ef1alpha48DElongation factor 1alpha48D0.028
brpbruchpilot0.028
inaEinactivation no afterpotential E0.028
CG15088CG15088 gene product from transcript CG15088-RC0.027
PtenCG5671 gene product from transcript CG5671-RB0.027
CG8211CG8211 gene product from transcript CG8211-RA0.027
LanB2Laminin B20.026
l(1)G0334lethal (1) G03340.026
CG13178CG13178 gene product from transcript CG13178-RA0.026
RicRas which interacts with Calmodulin0.026
beat-IVCG10152 gene product from transcript CG10152-RA0.026
CG1358CG1358 gene product from transcript CG1358-RD0.025
Or35aOdorant receptor 35a0.025
CG12214CG12214 gene product from transcript CG12214-RB0.025
DhDiuretic hormone0.025
CG32813CG32813 gene product from transcript CG32813-RE0.025
AlkCG8250 gene product from transcript CG8250-RA0.024
Snap25Synapse protein 250.023
CG5261CG5261 gene product from transcript CG5261-RB0.022
NmdmcNAD-dependent methylenetetrahydrofolate dehydrogenase0.022
DatDopamine N acetyltransferase0.022
GABA-B-R2metabotropic GABA-B receptor subtype 20.022
SKsmall conductance calcium-activated potassium channel0.021
CG3078CG3078 gene product from transcript CG3078-RA0.021
mAcR-60Cmuscarinic Acetylcholine Receptor 60C0.021
G-oalpha47AG protein oalpha 47A0.021
SbfSET domain binding factor0.020
dmdiminutive0.020
CG8036CG8036 gene product from transcript CG8036-RB0.020
CG30421CG30421 gene product from transcript CG30421-RA0.020
dpr5CG5308 gene product from transcript CG5308-RA0.020
pplpumpless0.020
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PGK1phosphoglycerate kinase 10.998
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.991
CALM1calmodulin 1 (phosphorylase kinase, delta)0.984
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.965
PDZD3PDZ domain containing 30.954
GABBR2gamma-aminobutyric acid (GABA) B receptor, 20.948
GUCY2Cguanylate cyclase 2C (heat stable enterotoxin receptor)0.943
CRHR1corticotropin releasing hormone receptor 10.877
NME1non-metastatic cells 1, protein (NM23A) expressed in0.805
TBXA2Rthromboxane A2 receptor0.787
COX4I1cytochrome c oxidase subunit IV isoform 10.775
ARRB1arrestin, beta 10.748
HPhaptoglobin0.744
MYD88myeloid differentiation primary response gene (88)0.730
AHCYadenosylhomocysteinase0.721
MAPTmicrotubule-associated protein tau0.717
PTGIRprostaglandin I2 (prostacyclin) receptor (IP)0.701
FHL1four and a half LIM domains 10.690
GABBR1gamma-aminobutyric acid (GABA) B receptor, 10.624
GUCY1B3guanylate cyclase 1, soluble, beta 30.622
OAS22'-5'-oligoadenylate synthetase 2, 69/71kDa0.603
FYNFYN oncogene related to SRC, FGR, YES0.581
MT1Ametallothionein 1A0.557
SNTB2syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)0.549
GUCY1A3guanylate cyclase 1, soluble, alpha 30.545
NOSTRINnitric oxide synthase trafficker0.533
ATP5A1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.530
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.516
IMMTinner membrane protein, mitochondrial0.514
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.509
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.487
CRHcorticotropin releasing hormone0.486
CAV1caveolin 1, caveolae protein, 22kDa0.471
WDYHV1WDYHV motif containing 10.469
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.449
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.440
ATP5C1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.430
PTENphosphatase and tensin homolog0.427
MPDZmultiple PDZ domain protein0.424
CALCRLcalcitonin receptor-like0.421
OAS12',5'-oligoadenylate synthetase 1, 40/46kDa0.420
OASL2'-5'-oligoadenylate synthetase-like0.417
UQCRC1ubiquinol-cytochrome c reductase core protein I0.399
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.396
OAS32'-5'-oligoadenylate synthetase 3, 100kDa0.395
SCP2sterol carrier protein 20.392
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.384
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.362
ATP2B2ATPase, Ca++ transporting, plasma membrane 20.356
ATP5G1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)0.333
PCDHA4protocadherin alpha 40.324
DEAF1deformed epidermal autoregulatory factor 1 (Drosophila)0.319
TPI1triosephosphate isomerase 10.317
GPIglucose-6-phosphate isomerase0.308
CD34CD34 molecule0.301
TBC1D10ATBC1 domain family, member 10A0.299
GARTphosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase0.292
ATP5F1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B10.286
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.271
RASSF5Ras association (RalGDS/AF-6) domain family member 50.270
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.267
VAC14Vac14 homolog (S. cerevisiae)0.259
ATP5HATP synthase, H+ transporting, mitochondrial Fo complex, subunit d0.256
KIFAP3kinesin-associated protein 30.245
BCRbreakpoint cluster region0.244
UCK2uridine-cytidine kinase 20.242
ADORA1adenosine A1 receptor0.232
TRIM14tripartite motif containing 140.232
EIF6eukaryotic translation initiation factor 60.224
LY6Elymphocyte antigen 6 complex, locus E0.221
RALGDSral guanine nucleotide dissociation stimulator0.218
ENGendoglin0.217
PPARGperoxisome proliferator-activated receptor gamma0.215
IFI6interferon, alpha-inducible protein 60.215
MX2myxovirus (influenza virus) resistance 2 (mouse)0.214
A2Malpha-2-macroglobulin0.210
PDE4DIPphosphodiesterase 4D interacting protein0.206
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.205
RGS20regulator of G-protein signaling 200.199
SLC25A3solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 30.196
CACNA1Ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.195
UQCRC2ubiquinol-cytochrome c reductase core protein II0.194
COX5Acytochrome c oxidase subunit Va0.194
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)0.192
ADORA2Aadenosine A2a receptor0.191
CCDC90Bcoiled-coil domain containing 90B0.188
CBX1chromobox homolog 10.187
PRPS2phosphoribosyl pyrophosphate synthetase 20.186
LCATlecithin-cholesterol acyltransferase0.184
MATKmegakaryocyte-associated tyrosine kinase0.182
ENO1enolase 1, (alpha)0.180
MEOX2mesenchyme homeobox 20.178
PDCD6IPprogrammed cell death 6 interacting protein0.178
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.171
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)0.169
RSAD2radical S-adenosyl methionine domain containing 20.167
SRIsorcin0.163
PSMG1proteasome (prosome, macropain) assembly chaperone 10.162
ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase0.160
PCNAproliferating cell nuclear antigen0.159
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Drd2dopamine receptor D20.991
Ppargperoxisome proliferator activated receptor gamma0.911
Cckbrcholecystokinin B receptor0.871
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.846
Pnp2purine-nucleoside phosphorylase 20.826
Arandrogen receptor0.825
Ctnnb1catenin (cadherin associated protein), beta 10.810
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.747
Hif1ahypoxia inducible factor 1, alpha subunit0.746
Ptenphosphatase and tensin homolog0.697
Lepleptin0.692
Nr3c1nuclear receptor subfamily 3, group C, member 10.674
Pnpla2patatin-like phospholipase domain containing 20.608
Tpi1triosephosphate isomerase 10.593
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.584
Adrb1adrenergic receptor, beta 10.553
Aldoaaldolase A, fructose-bisphosphate0.534
Ptgs2prostaglandin-endoperoxide synthase 20.530
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.518
Esr1estrogen receptor 1 (alpha)0.498
Ldhalactate dehydrogenase A0.477
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.470
Actr3ARP3 actin-related protein 3 homolog (yeast)0.439
Gpi1glucose phosphate isomerase 10.427
Pkm2pyruvate kinase, muscle0.404
Cdkn1bcyclin-dependent kinase inhibitor 1B0.387
Hrh2histamine receptor H20.383
Tac2tachykinin 20.378
Usp18ubiquitin specific peptidase 180.373
Sstr4somatostatin receptor 40.371
Ednrbendothelin receptor type B0.370
Npc1Niemann Pick type C10.369
Smosmoothened homolog (Drosophila)0.362
Kcna4potassium voltage-gated channel, shaker-related subfamily, member 40.355
Gm5506predicted gene 55060.341
Pgrprogesterone receptor0.336
Pgam1phosphoglycerate mutase 10.318
Kcns2K+ voltage-gated channel, subfamily S, 20.311
Pomcpro-opiomelanocortin-alpha0.308
Sim1single-minded homolog 1 (Drosophila)0.303
Leprleptin receptor0.289
Nrp1neuropilin 10.288
Atp4aATPase, H+/K+ exchanging, gastric, alpha polypeptide0.284
Nos1nitric oxide synthase 1, neuronal0.278
Adora2aadenosine A2a receptor0.265
Shc3src homology 2 domain-containing transforming protein C30.260
Kcnj3potassium inwardly-rectifying channel, subfamily J, member 30.260
Sstr2somatostatin receptor 20.260
Hprthypoxanthine guanine phosphoribosyl transferase0.254
Lhcgrluteinizing hormone/choriogonadotropin receptor0.253
Slc34a1solute carrier family 34 (sodium phosphate), member 10.248
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.244
Olfr1509olfactory receptor 15090.243
Edn1endothelin 10.231
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.231
Gucy1b3guanylate cyclase 1, soluble, beta 30.231
Kitkit oncogene0.230
Gjb5gap junction protein, beta 50.228
Ppyr1pancreatic polypeptide receptor 10.226
Wnt2bwingless related MMTV integration site 2b0.220
Agtr1aangiotensin II receptor, type 1a0.216
Amhanti-Mullerian hormone0.216
Dlg4discs, large homolog 4 (Drosophila)0.215
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.215
Sntb1syntrophin, basic 10.213
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.208
Adra2aadrenergic receptor, alpha 2a0.207
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.205
Rgs9regulator of G-protein signaling 90.201
Sstr1somatostatin receptor 10.198
Klklotho0.193
Cbln1cerebellin 1 precursor protein0.191
Syn2synapsin II0.190
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.190
Grid1glutamate receptor, ionotropic, delta 10.189
Acracrosin prepropeptide0.186
F2rl2coagulation factor II (thrombin) receptor-like 20.182
Abcg1ATP-binding cassette, sub-family G (WHITE), member 10.182
Gabbr2gamma-aminobutyric acid (GABA) B receptor, 20.181
Ikzf4IKAROS family zinc finger 40.179
Vdrvitamin D receptor0.178
Arntlaryl hydrocarbon receptor nuclear translocator-like0.175
Npy5rneuropeptide Y receptor Y50.174
Avpr2arginine vasopressin receptor 20.173
Ghrgrowth hormone receptor0.172
Nos3nitric oxide synthase 3, endothelial cell0.170
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.167
Oprk1opioid receptor, kappa 10.166
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.166
Cdk4cyclin-dependent kinase 40.165
Cplx1complexin 10.165
Grm1glutamate receptor, metabotropic 10.163
Gucy1a3guanylate cyclase 1, soluble, alpha 30.163
Prph2peripherin 20.161
Crhr1corticotropin releasing hormone receptor 10.160
Gpr44G protein-coupled receptor 440.156
Ern2endoplasmic reticulum (ER) to nucleus signalling 20.156
Casp14caspase 140.156
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.155
Mc5rmelanocortin 5 receptor0.154
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ATP4Atp4p0.999
ATP1Atp1p0.995
ATP18Atp18p0.975
CAB3Cab3p0.954
ATP5Atp5p0.938
ATP14Atp14p0.938
ATP7Atp7p0.917
ATP2Atp2p0.849
ADE12Ade12p0.807
ADE5,7Ade5,7p0.788
PRS1Prs1p0.776
ADE17Ade17p0.701
ATP16Atp16p0.684
IRA1Ira1p0.681
PRS2Prs2p0.644
ATP20Atp20p0.580
CYR1Cyr1p0.543
ATP17Atp17p0.496
MTD1Mtd1p0.483
ATP15Atp15p0.441
ADE13Ade13p0.425
ADE2Ade2p0.406
ADE1Ade1p0.380
MDS3Mds3p0.361
ATP3Atp3p0.316
PRS4Prs4p0.297
ADE6Ade6p0.263
ADE4Ade4p0.239
GPB2Gpb2p0.214
IRA2Ira2p0.213
VHS3Vhs3p0.173
HPT1Hpt1p0.169
COX9Cox9p0.169
MDL2Mdl2p0.159
MIR1Mir1p0.158
TIM11Tim11p0.140
INH1Inh1p0.136
TUF1Tuf1p0.134
PET9Pet9p0.117
ESF1Esf1p0.102
NDE1Nde1p0.098
URA4Ura4p0.094
URA2Ura2p0.093
COX8Cox8p0.091
LAT1Lat1p0.091
PRS3Prs3p0.088
RPM2Rpm2p0.083
COX7Cox7p0.080
COX4Cox4p0.077
YML018Chypothetical protein0.074
ATP6Atp6p0.073
IMD2Imd2p0.072
SOL1Sol1p0.070
LSC1Lsc1p0.068
PHO13Pho13p0.063
SER1Ser1p0.058
FRS1Frs1p0.057
GDH1Gdh1p0.057
URA6Ura6p0.057
PHO3Pho3p0.056
OLI1F0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP20.055
SHM2Shm2p0.051
ALD6Ald6p0.050
SIS2Sis2p0.049
SRD1Srd1p0.047
GDH3Gdh3p0.046
DLD3Dld3p0.046
PEX2Pex2p0.046
HEM12Hem12p0.043
YPL247Chypothetical protein0.043
LEU2Leu2p0.043
TIM10Tim10p0.042
HOR2Hor2p0.042
AGC1Agc1p0.042
TAZ1Taz1p0.041
TPO4Tpo4p0.041
THR4Thr4p0.041
ELP6Elp6p0.040
PUF4Puf4p0.040
CYC1Cyc1p0.039
YLR264C-Ahypothetical protein0.038
SPL2Spl2p0.038
VHS2Vhs2p0.037
TFG1Tfg1p0.037
YIR035Chypothetical protein0.037
FCY2Fcy2p0.037
FMN1Fmn1p0.036
ZIM17Zim17p0.036
QCR8Qcr8p0.035
HUG1Hug1p0.035
URA3Ura3p0.035
CUP1-1Cup1-1p0.035
DAS2Das2p0.035
PHM6Phm6p0.034
YHR033Whypothetical protein0.034
ADE8Ade8p0.034
HOHop0.033
KNH1Knh1p0.033
AIM24Aim24p0.033
YJR120Whypothetical protein0.033