The network for 'single organism catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

single organism catabolic process

A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves a single organism.

NameDescriptionProbabilityFunc Analog Organism
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.847
LOC293989cytochrome P450-like0.820
Anxa2annexin A20.761
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.714
Tpi1triosephosphate isomerase 10.712
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.680
Stxbp1syntaxin binding protein 10.624
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.578
Hk1hexokinase 10.573
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.563
Pkm2pyruvate kinase, muscle0.558
Aldoaaldolase A, fructose-bisphosphate0.558
Rhoaras homolog gene family, member A0.551
Ldhalactate dehydrogenase A0.543
Vdac1voltage-dependent anion channel 10.540
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.536
Lgals3lectin, galactoside-binding, soluble, 30.526
Acox3acyl-Coenzyme A oxidase 3, pristanoyl0.507
Decr12,4-dienoyl CoA reductase 1, mitochondrial0.473
Ech1enoyl coenzyme A hydratase 1, peroxisomal0.467
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.463
Car5acarbonic anhydrase 5a, mitochondrial0.447
Myo1dmyosin ID0.445
Etfdhelectron-transferring-flavoprotein dehydrogenase0.436
Gna12guanine nucleotide binding protein (G protein) alpha 120.430
Acaa2acetyl-Coenzyme A acyltransferase 20.427
Rxrgretinoid X receptor gamma0.416
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.406
Prlrprolactin receptor0.406
Arfip1ADP-ribosylation factor interacting protein 10.398
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.389
LOC689064beta-globin0.385
Myadmmyeloid-associated differentiation marker0.382
Acta2smooth muscle alpha-actin0.381
Prdx1peroxiredoxin 10.380
Pdk2pyruvate dehydrogenase kinase, isozyme 20.372
Hsd17b4hydroxysteroid (17-beta) dehydrogenase 40.363
Ftlferritin, light polypeptide0.362
Cd36CD36 molecule (thrombospondin receptor)0.360
Adkadenosine kinase0.358
Pygmphosphorylase, glycogen, muscle0.358
Ceacam10carcinoembryonic antigen-related cell adhesion molecule 100.357
Epas1endothelial PAS domain protein 10.357
Hsd17b10hydroxysteroid (17-beta) dehydrogenase 100.356
Mgst2microsomal glutathione S-transferase 20.356
Ucp2uncoupling protein 2 (mitochondrial, proton carrier)0.347
Nr1h4nuclear receptor subfamily 1, group H, member 40.339
Hsph1heat shock 105/110 protein 10.337
Casp3caspase 30.337
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.333
Cyp2c12cytochrome P450, family 2, subfamily c, polypeptide 120.332
Etfaelectron-transfer-flavoprotein, alpha polypeptide0.331
Ghrgrowth hormone receptor0.331
Aldh9a1aldehyde dehydrogenase 9 family, member A10.331
Ppm1aprotein phosphatase 1A, magnesium dependent, alpha isoform0.330
Pja2praja 2, RING-H2 motif containing0.324
Adora1adenosine A1 receptor0.324
Prrx1paired related homeobox 10.323
Ripk3receptor-interacting serine-threonine kinase 30.321
Tspotranslocator protein0.317
Odf4outer dense fiber of sperm tails 40.316
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.315
Gsta5glutathione S-transferase Yc2 subunit0.315
Mapre1microtubule-associated protein, RP/EB family, member 10.310
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.305
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.300
Vimvimentin0.293
Atp4bATPase, H+/K+ exchanging, beta polypeptide0.291
Hsd17b12hydroxysteroid (17-beta) dehydrogenase 120.290
Rab1RAB1, member RAS oncogene family0.290
Casq2calsequestrin 2 (cardiac muscle)0.288
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.285
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.283
LOC100134871beta globin minor gene0.282
Cmklr1chemokine-like receptor 10.282
Tkttransketolase0.280
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.280
Pnlippancreatic lipase0.278
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.276
Nr0b2nuclear receptor subfamily 0, group B, member 20.276
Slc8a1solute carrier family 8 (sodium/calcium exchanger), member 10.275
Gria2glutamate receptor, ionotropic, AMPA 20.274
Stk39serine/threonine kinase 39, STE20/SPS1 homolog (yeast)0.272
Eef2eukaryotic translation elongation factor 20.271
Gtf3c1general transcription factor IIIC, polypeptide 1, alpha0.271
Acox1acyl-Coenzyme A oxidase 1, palmitoyl0.267
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.266
Akr1b8aldo-keto reductase family 1, member B80.264
Anxa4annexin A40.258
Syngr2synaptogyrin 20.258
Fmnl1formin-like 10.257
Morf4l2mortality factor 4 like 20.256
Acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.253
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.253
Svs4seminal vesicle secretory protein 40.252
Tnni2troponin I type 2 (skeletal, fast)0.251
Acadsacyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain0.249
Ctsbcathepsin B0.249
Flt1FMS-related tyrosine kinase 10.248
Akap1A kinase (PRKA) anchor protein 10.246
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
goa-1Protein GOA-10.485
egl-18Protein EGL-180.480
par-5Protein PAR-50.365
sli-1Protein SLI-10.332
hsp-16.2Protein HSP-16.20.315
pkg-1Protein PKG-10.297
bar-1Protein BAR-10.282
gar-3Protein GAR-30.276
tpxl-1Protein TPXL-10.276
crt-1Protein CRT-10.270
unc-23Protein UNC-230.261
hsp-16.41Protein HSP-16.410.252
F44E5.4Protein F44E5.40.251
csr-1Protein CSR-10.251
pha-4Protein PHA-40.248
cin-4Protein CIN-40.245
hsp-16.1Protein HSP-16.10.239
gck-2Protein GCK-20.233
eat-6Protein EAT-60.229
spp-8Protein SPP-80.227
zyg-9Protein ZYG-90.221
fnta-1Protein FNTA-10.217
T08A11.2Protein T08A11.20.216
cpr-4Protein CPR-40.215
hsp-16.48Protein HSP-16.480.214
rod-1Protein ROD-10.213
bub-1Protein BUB-10.210
lec-1Protein LEC-10.207
gdh-1Protein GDH-10.207
miro-1Protein MIRO-10.197
dpf-3Protein DPF-30.197
zyg-8Protein ZYG-80.196
asp-6Protein ASP-60.194
zen-4Protein ZEN-40.191
aak-2Protein AAK-20.188
nhr-6Protein NHR-60.178
rhgf-2Protein RHGF-20.176
lin-5Protein LIN-50.174
sem-5Protein SEM-50.173
unc-32Protein UNC-320.172
ced-10Protein CED-100.168
ire-1Protein IRE-10.166
D1081.8Protein D1081.80.165
teg-4Protein TEG-40.164
cat-1Protein CAT-10.161
egl-44Protein EGL-440.159
ykt-6Protein YKT-60.156
hsp-70Protein HSP-700.156
glh-4Protein GLH-40.155
lag-1Protein LAG-10.153
CELE_C10C6.6Protein C10C6.60.153
daf-2Protein DAF-20.147
mcm-7Protein MCM-70.145
lev-1Protein LEV-10.143
fln-1Protein FLN-10.142
apc-2Protein APC-20.142
K07E3.4Protein K07E3.40.141
gpr-1Protein GPR-10.138
ant-1.1Protein ANT-1.10.137
lact-9Protein LACT-90.137
chc-1Protein CHC-10.135
prp-21Protein PRP-210.134
atp-2Protein ATP-20.134
got-2.1Protein GOT-2.10.132
lys-8Protein LYS-80.130
unc-45Protein UNC-450.130
C03A3.2Protein C03A3.20.128
gpr-2Protein GPR-20.128
ace-1Protein ACE-10.128
let-60Protein LET-600.126
scc-3Protein SCC-30.126
atx-3Protein ATX-30.126
amph-1Protein AMPH-10.124
hgo-1Protein HGO-10.124
gdi-1Protein GDI-10.124
Y110A7A.4Protein Y110A7A.40.124
fln-2Protein FLN-20.122
rab-5Protein RAB-50.122
mei-1Protein MEI-10.122
alh-3Protein ALH-30.118
F39B2.1Protein F39B2.10.117
prpf-4Protein PRPF-40.117
asah-1Protein ASAH-10.117
alh-4Protein ALH-40.116
F52D10.6Protein F52D10.60.116
mel-11Protein MEL-110.115
kle-2Protein KLE-20.115
nhr-45Protein NHR-450.114
lev-8Protein LEV-80.114
magi-1Protein MAGI-10.114
npp-19Protein NPP-190.113
F35G2.1Protein F35G2.10.112
unc-62Protein UNC-620.111
CELE_T26A8.4Protein T26A8.40.111
ncs-2Protein NCS-20.110
dli-1Protein DLI-10.110
itr-1Protein ITR-10.109
ina-1Protein INA-10.109
rbg-1Protein RBG-10.109
B0001.2Protein B0001.20.109
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
alcambactivated leukocyte cell adhesion molecule b0.080
gpiaglucose phosphate isomerase a0.046
ctsbacathepsin B, a0.037
gapdhsglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.030
pcnaproliferating cell nuclear antigen0.029
acheacetylcholinesterase0.028
aldocbaldolase C, fructose-bisphosphate, b0.026
myhz2myosin, heavy polypeptide 2, fast muscle specific0.026
wlswntless homolog (Drosophila)0.026
apobapolipoprotein B0.026
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.024
sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.022
prdx2peroxiredoxin 20.022
apoebapolipoprotein Eb0.020
tp53tumor protein p530.020
ckbbcreatine kinase, brain b0.020
ctsccathepsin C0.019
gro2groucho 20.019
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.019
zbtb4zinc finger and BTB domain containing 40.018
mtpmicrosomal triglyceride transfer protein0.018
ctszcathepsin Z0.018
zgc:100838zgc:1008380.018
bcl2B-cell leukemia/lymphoma 20.017
arf5ADP-ribosylation factor 50.016
egr1early growth response 10.016
cyp2y3cytochrome P450, family 2, subfamily Y, polypeptide 30.015
ef1aelongation factor 1-alpha0.015
myhz1.2myosin, heavy polypeptide 1.2, skeletal muscle0.015
bc2putative breast adenocarcinoma marker0.015
adkaadenosine kinase a0.014
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.014
acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.014
plxnb2aplexin b2a0.014
LOC569128hypothetical protein LOC5691280.014
atp1a1a.2ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide0.014
acadlacyl-Coenzyme A dehydrogenase, long chain0.014
pvrl1bpoliovirus receptor-related 1b0.014
hnf1baHNF1 homeobox Ba0.014
gartphosphoribosylglycinamide formyltransferase0.013
got2bglutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)0.013
ccnb2cyclin B20.013
maomonoamine oxidase0.013
zgc:64133zgc:641330.013
ccna2cyclin A20.013
bidaBH3 interacting domain death agonist0.013
tpm3tropomyosin 30.013
cyp3a65cytochrome P450, family 3, subfamily A, polypeptide 650.012
pgam2phosphoglycerate mutase 2 (muscle)0.012
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.012
gna14guanine nucleotide binding protein (G protein), alpha 140.012
hspd1heat shock 60kD protein 1 (chaperonin)0.012
sox2SRY-box containing gene 20.012
atp1b2aATPase, Na+/K+ transporting, beta 2a polypeptide0.012
aldh7a1aldehyde dehydrogenase 7 family, member A10.011
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.011
faf2Fas associated factor family member 20.011
hhexhematopoietically expressed homeobox0.011
tnnt3btroponin T3b, skeletal, fast0.011
olfm2olfactomedin 20.011
tnfatumor necrosis factor a (TNF superfamily, member 2)0.011
egr2bearly growth response 2b0.011
gnl2guanine nucleotide binding protein-like 2 (nucleolar)0.011
eif3s10eukaryotic translation initiation factor 3, subunit 10 (theta)0.011
racgap1Rac GTPase-activating protein 10.011
cd63Cd63 antigen0.011
aaasachalasia, adrenocortical insufficiency, alacrimia0.011
desmadesmin a0.011
spry4sprouty (Drosophila) homolog 40.010
nr5a5nuclear receptor subfamily 5, group A, member 50.010
ryr3ryanodine receptor 30.010
atp1a3bATPase, Na+/K+ transporting, alpha 3b polypeptide0.010
tpm4tropomyosin 40.010
uqcrc2bubiquinol-cytochrome c reductase core protein IIb0.010
ndufs2NADH dehydrogenase (ubiquinone) Fe-S protein 20.010
gnat2guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 20.010
gstp1glutathione S-transferase pi0.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.992
Rho1CG8416 gene product from transcript CG8416-RB0.896
dmdiminutive0.850
MadMothers against dpp0.830
PtenCG5671 gene product from transcript CG5671-RB0.819
CG7998CG7998 gene product from transcript CG7998-RA0.787
Atg8aAutophagy-specific gene 8a0.787
shishibire0.731
bskbasket0.709
rutrutabaga0.693
Vps16AVacuolar protein sorting 16A0.622
G-oalpha47AG protein oalpha 47A0.614
Syx7Syntaxin 70.574
Gapdh2Glyceraldehyde 3 phosphate dehydrogenase 20.527
AdhAlcohol dehydrogenase0.508
giggigas0.507
Ugt35aUDP-glycosyltransferase 35a0.505
Atg18Autophagy-specific gene 180.494
rlrolled0.493
Gp150CG5820 gene product from transcript CG5820-RA0.487
Aos1CG12276 gene product from transcript CG12276-RA0.481
Rab7Rab-protein 70.478
Eip63EEcdysone-induced protein 63E0.476
CG6116CG6116 gene product from transcript CG6116-RA0.473
Rac1CG2248 gene product from transcript CG2248-RA0.469
ATPsyn-gammaATP synthase-gamma chain0.468
drprdraper0.463
CycACyclin A0.444
Atg1Autophagy-specific gene 10.437
SosSon of sevenless0.432
staistathmin0.432
Rpd3CG7471 gene product from transcript CG7471-RA0.426
CG4389CG4389 gene product from transcript CG4389-RA0.418
drkdownstream of receptor kinase0.398
msnmisshapen0.389
SmoxSmad on X0.387
LanALaminin A0.384
GdhGlutamate dehydrogenase0.378
Dap160Dynamin associated protein 1600.373
rapsrapsynoid0.368
mbcmyoblast city0.367
TorTarget of rapamycin0.366
dosdaughter of sevenless0.366
Hnf4Hepatocyte nuclear factor 40.365
E(z)Enhancer of zeste0.353
Dhc64CDynein heavy chain 64C0.353
rheaCG6831 gene product from transcript CG6831-RA0.352
PknProtein kinase related to protein kinase N0.347
EnoEnolase0.346
ArgkArginine kinase0.336
ththread0.335
Dcr-2Dicer-20.333
ThiolaseCG4581 gene product from transcript CG4581-RA0.329
LvpDLarval visceral protein D0.323
cenG1Acentaurin gamma 1A0.313
LvpHLarval visceral protein H0.312
polyCG9829 gene product from transcript CG9829-RB0.310
locolocomotion defects0.307
RhoGAP68FCG6811 gene product from transcript CG6811-RA0.306
RASSF8CG5053 gene product from transcript CG5053-RA0.305
cnocanoe0.301
cltcricklet0.299
CamCalmodulin0.298
PEKpancreatic eIF-2alpha kinase0.293
Tcp-1etaCG8351 gene product from transcript CG8351-RA0.292
unc-104CG8566 gene product from transcript CG8566-RB0.290
benbendless0.287
cindrCIN85 and CD2AP orthologue0.281
rad50CG6339 gene product from transcript CG6339-RD0.280
CG6283CG6283 gene product from transcript CG6283-RA0.279
CG5362CG5362 gene product from transcript CG5362-RA0.270
htshu li tai shao0.265
PvrPDGF- and VEGF-receptor related0.263
Stat92ESignal-transducer and activator of transcription protein at 92E0.260
PyKPyruvate kinase0.259
Vha26Vacuolar H[+]-ATPase 26kD E subunit0.259
RhebCG1081 gene product from transcript CG1081-RA0.256
pimpimples0.255
LanB2Laminin B20.254
mei-41meiotic 410.253
zenzerknullt0.249
latlatheo0.247
plexBplexin B0.242
Sema-1aCG18405 gene product from transcript CG18405-RD0.235
RagACG11968 gene product from transcript CG11968-RA0.235
reptreptin0.232
pblpebble0.230
CycECyclin E0.229
eglegalitarian0.229
tumtumbleweed0.224
NacalphaNascent polypeptide associated complex protein alpha subunit0.223
StamSignal transducing adaptor molecule0.223
apapterous0.221
klgklingon0.221
CG1927CG1927 gene product from transcript CG1927-RA0.219
Lsd-2Lipid storage droplet-20.210
CatCatalase0.209
PTP-ERProtein tyrosine phosphatase-ERK/Enhancer of Ras10.208
trioCG18214 gene product from transcript CG18214-RA0.208
rolsrolling pebbles0.208
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
BMH2Bmh2p0.915
GLC7Glc7p0.884
HSP82Hsp82p0.841
CDC48Cdc48p0.814
ATG1Atg1p0.772
UBP15Ubp15p0.764
ATG20Atg20p0.737
HSV2Hsv2p0.736
GDI1Gdi1p0.735
CDC25Cdc25p0.674
REG1Reg1p0.662
ISW1Isw1p0.653
VAC8Vac8p0.651
ATG19Atg19p0.635
BEM3Bem3p0.623
STE11Ste11p0.603
HHT1Hht1p0.572
VAC7Vac7p0.567
PEX14Pex14p0.553
ATG13Atg13p0.541
YKU80Yku80p0.540
ENO2Eno2p0.523
KOG1Kog1p0.519
VPS21Vps21p0.517
SLG1Slg1p0.514
ATG26Atg26p0.514
ATG21Atg21p0.509
SHP1Shp1p0.506
TOR1Tor1p0.502
SWI1Swi1p0.500
FBA1Fba1p0.493
ATG3Atg3p0.492
STE2Ste2p0.489
RRD1Rrd1p0.486
STE4Ste4p0.484
GPM1Gpm1p0.483
GCD7Gcd7p0.474
CDC16Cdc16p0.472
RHO1Rho1p0.472
SNF3Snf3p0.469
ZWF1Zwf1p0.467
YIP3Yip3p0.461
GSY2Gsy2p0.460
MUK1Muk1p0.458
DOC1Doc1p0.455
BCY1Bcy1p0.455
MSS4Mss4p0.449
SAC6Sac6p0.447
TDH2Tdh2p0.443
VPS15Vps15p0.429
SSL1Ssl1p0.421
PDC1Pdc1p0.415
HHF1Hhf1p0.414
KEL1Kel1p0.406
ATG15Atg15p0.401
VPS41Vps41p0.400
YPT1Ypt1p0.396
YCK3Yck3p0.389
IMP2'Imp2'p0.379
SIT4Sit4p0.378
CDC27Cdc27p0.374
PDX3Pdx3p0.374
PPZ1Ppz1p0.372
PPH22Pph22p0.372
WHI2Whi2p0.369
SLT2Slt2p0.366
SSA1Ssa1p0.359
APC11Apc11p0.359
FKH1Fkh1p0.358
ADH1Adh1p0.354
ATG23Atg23p0.353
ENO1Eno1p0.351
MAL32Mal32p0.350
GND2Gnd2p0.343
CAK1Cak1p0.342
RPT3Rpt3p0.338
CKA2Cka2p0.337
SHO1Sho1p0.336
MAL11Mal11p0.335
TPI1Tpi1p0.332
CBF2Cbf2p0.331
HSP31Hsp31p0.331
ASP3-2Asp3-2p0.330
KRE6Kre6p0.330
CCZ1Ccz1p0.330
GCS1Gcs1p0.328
IML3Iml3p0.328
KES1Kes1p0.327
GRX1Grx1p0.326
TDH3Tdh3p0.326
FAA2Faa2p0.326
SSA2Ssa2p0.325
BOI1Boi1p0.320
ASP3-4Asp3-4p0.320
KIC1Kic1p0.320
YAP1Yap1p0.319
IMA1Ima1p0.318
GND1Gnd1p0.316
UNG1Ung1p0.316
COQ6Coq6p0.314