The network for 'regulation of membrane repolarization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of membrane repolarization

Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.

NameDescriptionProbabilityFunc Analog Organism
Atp1a2ATPase, Na+/K+ transporting, alpha 2 polypeptide0.390
Lrrc14bleucine rich repeat containing 14B0.318
Serpine2serine (or cysteine) peptidase inhibitor, clade E, member 20.316
Kcna5potassium voltage-gated channel, shaker-related subfamily, member 50.280
Pla2g5phospholipase A2, group V0.269
Inhainhibin alpha0.219
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.156
Kykyphoscoliosis peptidase0.094
Kcnk3potassium channel, subfamily K, member 30.087
Lrrc4bleucine rich repeat containing 4B0.086
Cntn2contactin 2 (axonal)0.086
Bcl2l10BCL2-like 10 (apoptosis facilitator)0.080
Makmale germ cell-associated kinase0.079
Pde4aphosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)0.079
Pdha2pyruvate dehydrogenase (lipoamide) alpha 20.063
Abcd2ATP-binding cassette, subfamily D (ALD), member 20.058
Dhrs7cdehydrogenase/reductase (SDR family) member 7C0.057
Adcy5adenylate cyclase 50.056
Hcn2hyperpolarization activated cyclic nucleotide-gated potassium channel 20.054
Kcnh2potassium voltage-gated channel, subfamily H (eag-related), member 20.051
Nkx2-1NK2 homeobox 10.050
Myl7myosin, light chain 7, regulatory0.048
Rpl3lribosomal protein L3-like0.047
Pygmphosphorylase, glycogen, muscle0.047
Itpr1inositol 1,4,5-triphosphate receptor, type 10.046
Alpk3alpha-kinase 30.045
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.044
Scn4bsodium channel, voltage-gated, type IV, beta0.044
Nt5m5',3'-nucleotidase, mitochondrial0.042
A2bp1ataxin 2 binding protein 10.042
Scn5asodium channel, voltage-gated, type V, alpha subunit0.041
Col9a1collagen, type IX, alpha 10.041
Rimbp2RIMS binding protein 20.041
Acsl6acyl-CoA synthetase long-chain family member 60.040
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.040
Znf498zinc finger protein 4980.040
Ppardperoxisome proliferator-activated receptor delta0.039
Rps6ka2ribosomal protein S6 kinase polypeptide 20.038
Neu3sialidase 3 (membrane sialidase)0.037
Neurl2neuralized homolog 2 (Drosophila)0.037
RGD1310269hypothetical LOC3144720.037
Myoz1myozenin 10.034
Tns1tensin 10.033
Shbgsex hormone binding globulin0.033
Sh3bgrSH3 domain binding glutamic acid-rich protein0.032
Appamyloid beta (A4) precursor protein0.032
Fgf16fibroblast growth factor 160.032
Map1amicrotubule-associated protein 1A0.030
Klhl13kelch-like 13 (Drosophila)0.030
Gzmkgranzyme K0.028
Phkg1phosphorylase kinase, gamma 10.027
Eef2eukaryotic translation elongation factor 20.026
BokBCL2-related ovarian killer0.026
Kcnj12potassium inwardly-rectifying channel, subfamily J, member 120.026
Coro6coronin 60.026
Serpine3serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 30.025
St3gal3ST3 beta-galactoside alpha-2,3-sialyltransferase 30.025
Rnf207ring finger protein 2070.025
Lama2laminin, alpha 20.025
Gpihbp1glycosylphosphatidylinositol anchored high density lipoprotein binding protein 10.025
Rxrgretinoid X receptor gamma0.024
Foxj1forkhead box J10.024
Cryba1crystallin, beta A10.024
Obscnobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.023
Tpcn1two pore segment channel 10.023
Me3malic enzyme 3, NADP(+)-dependent, mitochondrial0.023
Pik3ip1phosphoinositide-3-kinase interacting protein 10.022
LOC100359592paralemmin 30.022
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.021
Casq2calsequestrin 2 (cardiac muscle)0.020
Efnb1ephrin B10.020
Cav3caveolin 30.019
Cmya5cardiomyopathy associated 50.019
Gata4GATA binding protein 40.019
Phyhipphytanoyl-CoA 2-hydroxylase interacting protein0.019
Slc25a29solute carrier family 25, member 290.018
Phka1phosphorylase kinase, alpha 10.018
Ebf1early B-cell factor 10.018
Arvcfarmadillo repeat gene deleted in velo-cardio-facial syndrome0.017
Aqp2aquaporin 2 (collecting duct)0.017
Kcnk2potassium channel, subfamily K, member 20.017
Psgb1pregnancy-specific beta 1-glycoprotein0.017
Podxl2podocalyxin-like 20.017
Marealpha globin regulatory element containing gene0.017
Phldb1pleckstrin homology-like domain, family B, member 10.017
Notch3Notch homolog 3 (Drosophila)0.017
Prkcaprotein kinase C, alpha0.016
Asb12ankyrin repeat and SOCS box-containing 120.016
Mmd2monocyte to macrophage differentiation-associated 20.016
Dpysl3dihydropyrimidinase-like 30.016
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.016
Hist1h2bahistone cluster 1, H2ba0.016
LOC100360403ATP-binding cassette, sub-family C, member 9-like0.015
Wdr31WD repeat domain 310.015
LOC246295glycine-, glutamate-, thienylcyclohexylpiperidine-binding protein0.015
Myh6myosin, heavy chain 6, cardiac muscle, alpha0.015
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mybpc3myosin binding protein C, cardiac0.148
scn1bbsodium channel, voltage-gated, type I, beta b0.145
scn1basodium channel, voltage-gated, type I, beta a0.117
cyfip2cytoplasmic FMR1 interacting protein 20.074
myo7aamyosin VIIAa0.071
cx45.6connexin 45.60.067
pcsk5aproprotein convertase subtilisin/kexin type 5a0.058
slc8a1asolute carrier family 8 (sodium/calcium exchanger), member 1a0.056
vmhcventricular myosin heavy chain0.056
rdh12retinol dehydrogenase 12 (all-trans and 9-cis)0.055
scn2bsodium channel, voltage-gated, type II, beta0.045
trpv4transient receptor potential cation channel, subfamily V, member 40.042
tmietransmembrane inner ear0.037
slc17a8solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 80.036
scn12aasodium channel, voltage gated, type XII, alpha a0.034
aplp2amyloid beta (A4) precursor-like protein 20.034
lrrc10leucine rich repeat containing 100.033
ndrg4N-myc downstream regulated gene 40.032
olfm1bolfactomedin 1b0.031
tnnc1atroponin C type 1a (slow)0.031
nkx2.5NK2 transcription factor related 50.031
s100sS100 calcium binding protein S0.030
atp2b1aATPase, Ca++ transporting, plasma membrane 1a0.030
bcdo2lbeta-carotene 15, 15-dioxygenase 2, like0.029
scn12absodium channel, voltage gated, type XII, alpha b0.029
ctbp2lC-terminal binding protein 2, like0.028
gapdhsglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.027
ywhabatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a0.027
hey2hairy/enhancer-of-split related with YRPW motif 20.026
kcnj13potassium inwardly-rectifying channel, subfamily J, member 130.023
scn4basodium channel, voltage-gated, type IV, beta a0.023
gpr98G protein-coupled receptor 980.023
tardbpTAR DNA binding protein0.022
myl7myosin, light polypeptide 7, regulatory0.022
pcsk1proprotein convertase subtilisin/kexin type 10.022
prox1prospero-related homeobox gene 10.021
cmlc1cardiac myosin light chain-10.021
pdzd7aPDZ domain containing 7a0.021
nexnnexilin (F actin binding protein)0.021
rbm24bRNA binding motif protein 24b0.020
mylk3myosin light chain kinase 30.020
atp2b2ATPase, Ca++ transporting, plasma membrane 20.019
crip2cysteine-rich protein 20.019
scn3bsodium channel, voltage-gated, type III, beta0.018
myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.018
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.018
calcrlacalcitonin receptor-like a0.018
cadm2acell adhesion molecule 2a0.018
s100tS100 calcium binding protein T0.018
slc2a11bsolute carrier family 2 (facilitated glucose transporter), member 11b0.017
mdh1bmalate dehydrogenase 1b, NAD (soluble)0.017
scn4absodium channel, voltage-gated, type IV, alpha, b0.017
pobpartial optokinetic response b0.016
dpf3D4, zinc and double PHD fingers, family 30.016
fstl1bfollistatin-like 1b0.015
LOC569642hypothetical protein LOC5696420.015
grnagranulin a0.015
wnt11rwingless-type MMTV integration site family, member 11, related0.015
rbm24aRNA binding motif protein 24a0.015
ywhaqatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a0.015
rer1RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)0.014
wdr16WD repeat domain 160.014
ldb3bLIM domain binding 3b0.013
dbtdihydrolipoamide branched chain transacylase E20.013
ptpraprotein tyrosine phosphatase, receptor type, A0.012
frem1aFras1 related extracellular matrix 1a0.012
spry4sprouty (Drosophila) homolog 40.012
tfpi2tissue factor pathway inhibitor 20.012
pcdh15aprotocadherin 15a0.012
atp6v0cbATPase, H+ transporting, lysosomal, V0 subunit c, b0.012
mpzmyelin protein zero0.012
bmp4bone morphogenetic protein 40.012
pcsk2proprotein convertase subtilisin/kexin type 20.011
prom1aprominin 1a0.011
slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.011
csrp3cysteine and glycine-rich protein 3 (cardiac LIM protein)0.011
cyp19a1bcytochrome P450, family 19, subfamily A, polypeptide 1b0.011
bmp10bone morphogenetic protein 100.011
eya4eyes absent homolog 4 (Drosophila)0.011
mpped2metallophosphoesterase domain containing 20.011
ush1cUsher syndrome 1C (autosomal recessive, severe)0.011
sat1bspermidine/spermine N1-acetyl transferase 1b0.011
ltbp3latent transforming growth factor beta binding protein 30.011
zerg24potassium voltage-gated channel zerg240.011
il6rinterleukin 6 receptor0.010
limk1LIM domain kinase 10.010
smyd1bSET and MYND domain containing 1b0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide1.000
SMURF2SMAD specific E3 ubiquitin protein ligase 20.999
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.997
KCNB1potassium voltage-gated channel, Shab-related subfamily, member 10.991
DLG4discs, large homolog 4 (Drosophila)0.960
OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.917
MPZL3myelin protein zero-like 30.899
MPZL2myelin protein zero-like 20.888
KCNIP2Kv channel interacting protein 20.874
SCN5Asodium channel, voltage-gated, type V, alpha subunit0.830
LIN7Blin-7 homolog B (C. elegans)0.790
ACTN2actinin, alpha 20.761
ABCA1ATP-binding cassette, sub-family A (ABC1), member 10.702
TJP1tight junction protein 1 (zona occludens 1)0.641
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.628
SNTG2syntrophin, gamma 20.625
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.612
MAPK12mitogen-activated protein kinase 120.571
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.515
KCNA4potassium voltage-gated channel, shaker-related subfamily, member 40.426
ZFYVE9zinc finger, FYVE domain containing 90.357
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.302
SPTBspectrin, beta, erythrocytic0.290
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.222
MYOZ1myozenin 10.163
DLGAP1discs, large (Drosophila) homolog-associated protein 10.117
ANKRD13Aankyrin repeat domain 13A0.109
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.107
WWP1WW domain containing E3 ubiquitin protein ligase 10.107
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.095
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.091
KCNC1potassium voltage-gated channel, Shaw-related subfamily, member 10.086
EHD1EH-domain containing 10.084
NEDD4neural precursor cell expressed, developmentally down-regulated 40.084
CLCN3chloride channel 30.079
FBXL15F-box and leucine-rich repeat protein 150.078
KCNIP1Kv channel interacting protein 10.073
KCNA5potassium voltage-gated channel, shaker-related subfamily, member 50.072
RYR2ryanodine receptor 2 (cardiac)0.066
KCNH1potassium voltage-gated channel, subfamily H (eag-related), member 10.065
ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 80.062
GRIN2Cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.058
ATP2B2ATPase, Ca++ transporting, plasma membrane 20.057
MARK2MAP/microtubule affinity-regulating kinase 20.054
BAI1brain-specific angiogenesis inhibitor 10.053
KCNG3potassium voltage-gated channel, subfamily G, member 30.049
RAPGEF2Rap guanine nucleotide exchange factor (GEF) 20.043
RHAGRh-associated glycoprotein0.040
FRS2fibroblast growth factor receptor substrate 20.039
CALM1calmodulin 1 (phosphorylase kinase, delta)0.037
CAV1caveolin 1, caveolae protein, 22kDa0.035
RHOAras homolog gene family, member A0.035
POU5F1POU class 5 homeobox 10.034
CDC25Bcell division cycle 25 homolog B (S. pombe)0.034
MDM2Mdm2 p53 binding protein homolog (mouse)0.033
BSNbassoon (presynaptic cytomatrix protein)0.031
ATP2B3ATPase, Ca++ transporting, plasma membrane 30.027
SMURF1SMAD specific E3 ubiquitin protein ligase 10.026
HRH3histamine receptor H30.024
WNK1WNK lysine deficient protein kinase 10.024
DPP6dipeptidyl-peptidase 60.023
NEDD9neural precursor cell expressed, developmentally down-regulated 90.023
SPTA1spectrin, alpha, erythrocytic 1 (elliptocytosis 2)0.021
KCNJ4potassium inwardly-rectifying channel, subfamily J, member 40.021
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like0.021
KCNB2potassium voltage-gated channel, Shab-related subfamily, member 20.020
WWP2WW domain containing E3 ubiquitin protein ligase 20.020
ING1inhibitor of growth family, member 10.020
SEZ6Lseizure related 6 homolog (mouse)-like0.020
DLGAP2discs, large (Drosophila) homolog-associated protein 20.020
USP2ubiquitin specific peptidase 20.020
CCKBRcholecystokinin B receptor0.019
MAP3K2mitogen-activated protein kinase kinase kinase 20.019
RNF168ring finger protein 1680.019
KCNJ10potassium inwardly-rectifying channel, subfamily J, member 100.018
BADBCL2-associated agonist of cell death0.018
KCNJ6potassium inwardly-rectifying channel, subfamily J, member 60.018
KCNJ16potassium inwardly-rectifying channel, subfamily J, member 160.017
UBQLN2ubiquilin 20.017
GRM7glutamate receptor, metabotropic 70.016
KCNA2potassium voltage-gated channel, shaker-related subfamily, member 20.016
KLF5Kruppel-like factor 5 (intestinal)0.016
SLITRK3SLIT and NTRK-like family, member 30.016
SMAD1SMAD family member 10.016
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)0.016
MAP3K1mitogen-activated protein kinase kinase kinase 10.016
ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)0.016
NTRK3neurotrophic tyrosine kinase, receptor, type 30.016
NLGN1neuroligin 10.014
RBFOX1RNA binding protein, fox-1 homolog (C. elegans) 10.014
RGS6regulator of G-protein signaling 60.014
SMAD4SMAD family member 40.014
CACNA1Ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.014
SMAD5SMAD family member 50.014
SOX7SRY (sex determining region Y)-box 70.014
CYP46A1cytochrome P450, family 46, subfamily A, polypeptide 10.014
SYN2synapsin II0.014
VMP1vacuole membrane protein 10.014
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Scn5asodium channel, voltage-gated, type V, alpha0.939
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.840
Ryr2ryanodine receptor 2, cardiac0.775
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.479
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.298
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.270
Dtnadystrobrevin alpha0.193
Mybpc3myosin binding protein C, cardiac0.178
Kcnj10potassium inwardly-rectifying channel, subfamily J, member 100.159
Lhx6LIM homeobox protein 60.136
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.118
Thrbthyroid hormone receptor beta0.115
Cdh23cadherin 23 (otocadherin)0.114
Hcn4hyperpolarization-activated, cyclic nucleotide-gated K+ 40.095
Dsc1desmocollin 10.086
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.084
Dmddystrophin, muscular dystrophy0.079
Cacnb2calcium channel, voltage-dependent, beta 2 subunit0.075
Tnnc2troponin C2, fast0.070
Adcyap1r1adenylate cyclase activating polypeptide 1 receptor 10.067
Tjp1tight junction protein 10.065
Rnf112ring finger protein 1120.062
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.061
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.061
Kcnk3potassium channel, subfamily K, member 30.059
Cacnb4calcium channel, voltage-dependent, beta 4 subunit0.057
Hrchistidine rich calcium binding protein0.056
Itga7integrin alpha 70.054
Ldb3LIM domain binding 30.052
Tbx5T-box 50.046
Klk6kallikrein related-peptidase 60.045
Slc26a4solute carrier family 26, member 40.041
Tcf15transcription factor 150.039
Atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.037
Kcnj12potassium inwardly-rectifying channel, subfamily J, member 120.037
Xirp1xin actin-binding repeat containing 10.037
Grid2glutamate receptor, ionotropic, delta 20.036
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.034
Myh2myosin, heavy polypeptide 2, skeletal muscle, adult0.033
Gjb6gap junction protein, beta 60.033
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.033
Ryr1ryanodine receptor 1, skeletal muscle0.033
Tnni2troponin I, skeletal, fast 20.033
Slc17a8solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 80.032
KelKell blood group0.032
Rgs8regulator of G-protein signaling 80.031
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.031
Tnnt3troponin T3, skeletal, fast0.030
Lama2laminin, alpha 20.030
Rtn2reticulon 2 (Z-band associated protein)0.029
Cntn4contactin 40.029
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.029
Pygmmuscle glycogen phosphorylase0.027
Abcc8ATP-binding cassette, sub-family C (CFTR/MRP), member 80.024
Hcn2hyperpolarization-activated, cyclic nucleotide-gated K+ 20.024
Syn2synapsin II0.024
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.023
Aplnrapelin receptor0.023
Slurp1secreted Ly6/Plaur domain containing 10.022
Gjb2gap junction protein, beta 20.022
Nos3nitric oxide synthase 3, endothelial cell0.021
Bfsp1beaded filament structural protein 1, in lens-CP940.021
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.021
Eef1a2eukaryotic translation elongation factor 1 alpha 20.021
Adra2cadrenergic receptor, alpha 2c0.021
Sstr3somatostatin receptor 30.020
Adam22a disintegrin and metallopeptidase domain 220.020
Myoz1myozenin 10.019
Srrm4serine/arginine repetitive matrix 40.019
Sult4a1sulfotransferase family 4A, member 10.019
Tulp1tubby like protein 10.018
Mpzmyelin protein zero0.018
Dmpkdystrophia myotonica-protein kinase0.018
SpegSPEG complex locus0.018
Cox6a2cytochrome c oxidase, subunit VI a, polypeptide 20.017
Phkg1phosphorylase kinase gamma 10.017
Chrm3cholinergic receptor, muscarinic 3, cardiac0.017
Adam23a disintegrin and metallopeptidase domain 230.016
Gja5gap junction protein, alpha 50.016
Krt25keratin 250.016
Dnajb5DnaJ (Hsp40) homolog, subfamily B, member 50.016
Cnr1cannabinoid receptor 1 (brain)0.016
Rgs6regulator of G-protein signaling 60.015
Hsf4heat shock transcription factor 40.015
Sgcasarcoglycan, alpha (dystrophin-associated glycoprotein)0.015
Myom2myomesin 20.015
Zfpm2zinc finger protein, multitype 20.015
Npas1neuronal PAS domain protein 10.015
Srpk3serine/arginine-rich protein specific kinase 30.015
Upk3buroplakin 3B0.015
Scn8asodium channel, voltage-gated, type VIII, alpha0.014
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism