The network for 'cellular response to corticosteroid stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to corticosteroid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.

NameDescriptionProbabilityFunc Analog Organism
RT1-BbRT1 class II, locus Bb0.887
Agtr1aangiotensin II receptor, type 1a0.866
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.670
LOC494499LOC494499 protein0.634
Ephx1epoxide hydrolase 1, microsomal0.577
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.548
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.528
Anxa1annexin A10.496
Gstm1glutathione S-transferase mu 10.492
Anxa5annexin A50.483
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.455
Ugt2b37UDP-glucuronosyltransferase 2 family, member 370.354
Slco1a1solute carrier organic anion transporter family, member 1a10.350
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.311
Metmet proto-oncogene0.299
Pcdhb12protocadherin beta 120.266
Fn1fibronectin 10.264
C8bcomplement component 8, beta polypeptide0.251
Gja6gap junction protein, alpha 60.248
Lgals3lectin, galactoside-binding, soluble, 30.245
Cyp2c11cytochrome P450, subfamily 2, polypeptide 110.244
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.244
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.238
Gsta3glutathione S-transferase A30.223
Slc22a7solute carrier family 22 (organic anion transporter), member 70.223
Dnase1l3deoxyribonuclease 1-like 30.223
Mgst1microsomal glutathione S-transferase 10.217
Akr1c18aldo-keto reductase family 1, member C180.216
Slc26a1solute carrier family 26 (sulfate transporter), member 10.211
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.208
Gstm2glutathione S-transferase mu 20.203
Ces1ccarboxylesterase 1C0.201
Pla1aphospholipase A1 member A0.198
FcgrtFc fragment of IgG, receptor, transporter, alpha0.196
Galr2galanin receptor 20.195
Crygfcrystallin, gamma F0.194
Sod3superoxide dismutase 3, extracellular0.191
Mgst2microsomal glutathione S-transferase 20.189
Akr1c14aldo-keto reductase family 1, member C140.184
Sstr5somatostatin receptor 50.184
Ifitm3interferon induced transmembrane protein 30.183
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.180
Pemtphosphatidylethanolamine N-methyltransferase0.180
Chrna7cholinergic receptor, nicotinic, alpha 70.176
Aqp9aquaporin 90.163
Cyp2g1cytochrome P450, family 2, subfamily g, polypeptide 10.163
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.161
Slc27a2solute carrier family 27 (fatty acid transporter), member 20.160
Actr2ARP2 actin-related protein 2 homolog (yeast)0.156
Anxa2annexin A20.154
Cd44Cd44 molecule0.151
Sult2al1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 10.151
Ggt5gamma-glutamyltransferase 50.149
Csf1colony stimulating factor 1 (macrophage)0.148
Cd9CD9 molecule0.148
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.147
RT1-BaRT1 class II, locus Ba0.145
Flt1FMS-related tyrosine kinase 10.143
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.143
Errfi1ERBB receptor feedback inhibitor 10.141
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.141
Cd14CD14 molecule0.140
Accn1amiloride-sensitive cation channel 1, neuronal0.136
Ugt1a5UDP glucuronosyltransferase 1 family, polypeptide A50.135
Shank2SH3 and multiple ankyrin repeat domains 20.135
Serpina4serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 40.132
Ptgs2prostaglandin-endoperoxide synthase 20.131
Slco2a1solute carrier organic anion transporter family, member 2a10.129
Crhr1corticotropin releasing hormone receptor 10.129
Ptgfrprostaglandin F receptor0.129
Sult1c3sulfotransferase family, cytosolic, 1C, member 30.127
Lbplipopolysaccharide binding protein0.126
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.125
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.124
Id3inhibitor of DNA binding 30.124
Gja4gap junction protein, alpha 40.123
Acaa1bacetyl-Coenzyme A acyltransferase 1B0.122
Il1rl1interleukin 1 receptor-like 10.122
Gabrpgamma-aminobutyric acid (GABA-A) receptor, pi0.122
Accn2amiloride-sensitive cation channel 2, neuronal0.120
Testintestin gene0.117
Lhx1LIM homeobox 10.116
RT1-DaRT1 class II, locus Da0.115
CartptCART prepropeptide0.115
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.114
Crisp1cysteine-rich secretory protein 10.114
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.112
Mcpt3mast cell peptidase 30.110
Myh4myosin, heavy chain 4, skeletal muscle0.110
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.110
Mmp2matrix metallopeptidase 20.110
Aqp8aquaporin 80.110
Slc22a18solute carrier family 22, member 180.107
Apohapolipoprotein H (beta-2-glycoprotein I)0.107
F9coagulation factor IX0.106
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.106
Onecut1one cut homeobox 10.104
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.586
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.524
ANXA1annexin A10.493
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.478
NRP1neuropilin 10.465
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.344
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.326
RNF144Bring finger protein 144B0.324
APAF1apoptotic peptidase activating factor 10.305
S100A10S100 calcium binding protein A100.276
FSTL1follistatin-like 10.193
XIAPX-linked inhibitor of apoptosis0.181
PLAUplasminogen activator, urokinase0.151
PLATplasminogen activator, tissue0.120
CASP3caspase 3, apoptosis-related cysteine peptidase0.081
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.072
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.062
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.059
NRIP1nuclear receptor interacting protein 10.057
EIF3Feukaryotic translation initiation factor 3, subunit F0.056
EMP1epithelial membrane protein 10.049
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.048
ARIH2ariadne homolog 2 (Drosophila)0.043
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.040
SMPD1sphingomyelin phosphodiesterase 1, acid lysosomal0.040
IFNGR1interferon gamma receptor 10.038
MPDZmultiple PDZ domain protein0.038
ANXA5annexin A50.036
DNMT3ADNA (cytosine-5-)-methyltransferase 3 alpha0.035
NMT2N-myristoyltransferase 20.026
HBP1HMG-box transcription factor 10.025
THBS1thrombospondin 10.023
FNDC3Bfibronectin type III domain containing 3B0.022
ACTN2actinin, alpha 20.022
AHRaryl hydrocarbon receptor0.020
CAV1caveolin 1, caveolae protein, 22kDa0.018
UHRF1ubiquitin-like with PHD and ring finger domains 10.018
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.018
IQGAP1IQ motif containing GTPase activating protein 10.017
KLHL24kelch-like 24 (Drosophila)0.016
PGFplacental growth factor0.015
ARNTaryl hydrocarbon receptor nuclear translocator0.015
TGFB3transforming growth factor, beta 30.014
S100A11S100 calcium binding protein A110.014
GRIP1glutamate receptor interacting protein 10.014
RNF31ring finger protein 310.013
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.012
MBNL1muscleblind-like (Drosophila)0.012
HLA-DPB1major histocompatibility complex, class II, DP beta 10.011
NCOA1nuclear receptor coactivator 10.010
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Casp4caspase 4, apoptosis-related cysteine peptidase0.726
Vegfavascular endothelial growth factor A0.703
Tgfb1transforming growth factor, beta 10.536
Ptpn11protein tyrosine phosphatase, non-receptor type 110.530
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.506
Trim55tripartite motif-containing 550.407
Ptgs2prostaglandin-endoperoxide synthase 20.342
Pax3paired box gene 30.326
Stat3signal transducer and activator of transcription 30.281
Ren1renin 1 structural0.279
Tgfbr2transforming growth factor, beta receptor II0.265
Cdkn1bcyclin-dependent kinase inhibitor 1B0.232
Lyz2lysozyme 20.210
Cd74CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)0.196
Bmpr1abone morphogenetic protein receptor, type 1A0.178
Leprleptin receptor0.159
Trim63tripartite motif-containing 630.136
Pitx2paired-like homeodomain transcription factor 20.135
Casp1caspase 10.130
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.128
Trp53transformation related protein 530.124
Foxc1forkhead box C10.097
Osmroncostatin M receptor0.095
Esr1estrogen receptor 1 (alpha)0.095
Fbn1fibrillin 10.087
Gbp5guanylate binding protein 50.084
Slc12a1solute carrier family 12, member 10.082
Hif1ahypoxia inducible factor 1, alpha subunit0.081
Dmddystrophin, muscular dystrophy0.079
Shhsonic hedgehog0.079
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.078
Gata4GATA binding protein 40.077
Aim2absent in melanoma 20.075
Il18interleukin 180.071
Fgfr2fibroblast growth factor receptor 20.071
Hand2heart and neural crest derivatives expressed transcript 20.071
Ghrgrowth hormone receptor0.070
Prlrprolactin receptor0.066
Zeb1zinc finger E-box binding homeobox 10.064
Csf1colony stimulating factor 1 (macrophage)0.060
Meox2mesenchyme homeobox 20.059
Pax7paired box gene 70.053
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.052
FasFas (TNF receptor superfamily member 6)0.051
Nos3nitric oxide synthase 3, endothelial cell0.051
Loxlysyl oxidase0.047
Tnni2troponin I, skeletal, fast 20.046
WwoxWW domain-containing oxidoreductase0.045
Agtr1aangiotensin II receptor, type 1a0.045
Errfi1ERBB receptor feedback inhibitor 10.043
Foxp3forkhead box P30.042
Kitkit oncogene0.041
Esr2estrogen receptor 2 (beta)0.039
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.036
Il1binterleukin 1 beta0.035
Il6stinterleukin 6 signal transducer0.034
Jak2Janus kinase 20.033
Vdrvitamin D receptor0.032
PycardPYD and CARD domain containing0.031
Nos1nitric oxide synthase 1, neuronal0.031
Arntaryl hydrocarbon receptor nuclear translocator0.030
Prrx1paired related homeobox 10.030
Apcadenomatosis polyposis coli0.030
Akr1c6aldo-keto reductase family 1, member C60.029
Socs5suppressor of cytokine signaling 50.027
Rb1retinoblastoma 10.027
RoraRAR-related orphan receptor alpha0.026
Il1r1interleukin 1 receptor, type I0.025
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.025
Bdkrb2bradykinin receptor, beta 20.025
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.025
Bmp2bone morphogenetic protein 20.025
Myod1myogenic differentiation 10.024
Nr3c1nuclear receptor subfamily 3, group C, member 10.024
Fbxo32F-box protein 320.023
H2-Eb1histocompatibility 2, class II antigen E beta0.022
Fgfr1fibroblast growth factor receptor 10.022
Hbegfheparin-binding EGF-like growth factor0.022
Nf1neurofibromatosis 10.021
Ppargperoxisome proliferator activated receptor gamma0.021
Ccl2chemokine (C-C motif) ligand 20.021
Myf5myogenic factor 50.021
Wfikkn2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.021
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.021
Arandrogen receptor0.021
F13bcoagulation factor XIII, beta subunit0.020
Ece1endothelin converting enzyme 10.020
Tgfb2transforming growth factor, beta 20.020
Csf1rcolony stimulating factor 1 receptor0.020
Kiss1KiSS-1 metastasis-suppressor0.020
Ptenphosphatase and tensin homolog0.018
Cav1caveolin 1, caveolae protein0.018
Plauplasminogen activator, urokinase0.018
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism