The network for 'negative regulation of nucleic acid templated transcription' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of nucleic acid templated transcription

Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.

NameDescriptionProbabilityFunc Analog Organism
JunJun oncogene0.956
Dusp1dual specificity phosphatase 10.825
Junbjun B proto-oncogene0.824
FosFBJ osteosarcoma oncogene0.811
Nfibnuclear factor I/B0.739
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.546
Ppp2cbprotein phosphatase 2, catalytic subunit, beta isoform0.544
Ahraryl hydrocarbon receptor0.471
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.407
Adra2badrenergic, alpha-2B-, receptor0.399
Rhobras homolog gene family, member B0.397
Pcnaproliferating cell nuclear antigen0.396
Hes1hairy and enhancer of split 1 (Drosophila)0.396
Btg2BTG family, member 20.394
Tcf4transcription factor 40.375
Hoxc4homeo box C40.359
Vimvimentin0.355
Pgam1phosphoglycerate mutase 1 (brain)0.323
Eif4heukaryotic translation initiation factor 4H0.317
Ier2immediate early response 20.315
Nedd4neural precursor cell expressed, developmentally down-regulated 40.313
Nfyanuclear transcription factor-Y alpha0.305
Hand2heart and neural crest derivatives expressed 20.301
Nr2f2nuclear receptor subfamily 2, group F, member 20.300
Dusp6dual specificity phosphatase 60.300
Hoxb7homeo box B70.294
Klf2Kruppel-like factor 2 (lung)0.290
Shox2short stature homeobox 20.277
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.270
Fat2FAT tumor suppressor homolog 2 (Drosophila)0.266
Slc4a1solute carrier family 4 (anion exchanger), member 10.260
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.259
Id1inhibitor of DNA binding 10.245
Ptprkprotein tyrosine phosphatase, receptor type, K, extracellular region0.240
Alx1ALX homeobox 10.240
Sp1Sp1 transcription factor0.233
Hnrnprheterogeneous nuclear ribonucleoprotein R0.233
Klf6Kruppel-like factor 60.232
Otx1orthodenticle homeobox 10.231
Pde4bphosphodiesterase 4B, cAMP specific0.231
Taok1TAO kinase 10.231
Purbpurine rich element binding protein B0.230
Stat6signal transducer and activator of transcription 60.230
Tgfbr2transforming growth factor, beta receptor II0.229
Shhsonic hedgehog0.222
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.221
Smad7SMAD family member 70.218
Tcfe2atranscription factor E2a0.216
Mycmyelocytomatosis oncogene0.214
S100a8S100 calcium binding protein A80.211
Nr1d2nuclear receptor subfamily 1, group D, member 20.207
Fzd2frizzled homolog 2 (Drosophila)0.206
Dynll1dynein light chain LC8-type 10.202
S100a9S100 calcium binding protein A90.199
Hoxd3homeo box D30.197
Trim28tripartite motif-containing 280.196
Hist1h1dhistone cluster 1, H1d0.196
Metmet proto-oncogene0.192
Palmparalemmin0.191
Abcc1ATP-binding cassette, subfamily C (CFTR/MRP), member 10.190
Tulp1tubby like protein 10.189
Grk1G protein-coupled receptor kinase 10.188
Anxa2annexin A20.186
Kdm6blysine (K)-specific demethylase 6B0.186
Gse1genetic suppressor element 10.184
Errfi1ERBB receptor feedback inhibitor 10.183
Asgr1asialoglycoprotein receptor 10.180
Wbp11WW domain binding protein 110.178
Neurog1neurogenin 10.177
Smad6SMAD family member 60.177
Rap1bRAP1B, member of RAS oncogene family0.175
Siah1aseven in absentia 1A0.174
Crybb3crystallin, beta B30.171
Dgkzdiacylglycerol kinase zeta0.171
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.171
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.169
Gastgastrin0.168
Vax2ventral anterior homeobox 20.165
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.162
Cd9CD9 molecule0.160
Atf3activating transcription factor 30.158
Cdc42cell division cycle 42 (GTP binding protein)0.156
Megf10multiple EGF-like domains 100.154
Uts2rurotensin 2 receptor0.151
Dlg4discs, large homolog 4 (Drosophila)0.151
DbpD site of albumin promoter (albumin D-box) binding protein0.150
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.149
A4galtalpha 1,4-galactosyltransferase0.148
Bmp7bone morphogenetic protein 70.144
Homer3homer homolog 3 (Drosophila)0.144
St8sia2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.142
Cysscystatin S0.142
Ptpn1protein tyrosine phosphatase, non-receptor type 10.140
Gata3GATA binding protein 30.138
Stip1stress-induced phosphoprotein 10.136
Foxd1forkhead box D10.136
Nrp1neuropilin 10.135
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.135
S100a10S100 calcium binding protein A100.134
Cd63Cd63 molecule0.134
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.956
pha-4Protein PHA-40.725
his-1Protein HIS-10.586
his-16Protein HIS-160.570
elt-6Protein ELT-60.507
his-64Protein HIS-640.497
his-61Protein HIS-610.451
let-502Protein LET-5020.415
mes-4Protein MES-40.394
ceh-27Protein CEH-270.345
F39B2.1Protein F39B2.10.329
nhr-67Protein NHR-670.325
his-46Protein HIS-460.317
egl-46Protein EGL-460.306
let-418Protein LET-4180.277
atg-2Protein ATG-20.264
vab-3Protein VAB-30.264
mcm-2Protein MCM-20.250
his-29Protein HIS-290.215
his-3Protein HIS-30.215
lmn-1Protein LMN-10.208
his-45Protein HIS-450.200
rnr-1Protein RNR-10.198
lsy-2Protein LSY-20.197
klp-19Protein KLP-190.197
his-5Protein HIS-50.196
daf-3Protein DAF-30.193
his-38Protein HIS-380.187
nhr-25Protein NHR-250.186
his-42Protein HIS-420.186
hcp-3Protein HCP-30.184
mab-5Protein MAB-50.180
prp-8Protein PRP-80.176
mat-3Protein MAT-30.174
nhr-2Protein NHR-20.167
tbx-8Protein TBX-80.166
his-30Protein HIS-300.158
mcm-7Protein MCM-70.156
lin-11Protein LIN-110.155
egl-27Protein EGL-270.150
ran-1Protein RAN-10.149
unc-62Protein UNC-620.147
hbl-1Protein HBL-10.145
plc-1Protein PLC-10.141
hlh-1Protein HLH-10.140
attf-2Protein ATTF-20.139
cdt-2Protein CDT-20.138
hil-2Protein HIL-20.138
cnd-1Protein CND-10.136
mix-1Protein MIX-10.135
his-51Protein HIS-510.132
lin-17Protein LIN-170.126
zyg-1Protein ZYG-10.121
his-9Protein HIS-90.120
lin-53Protein LIN-530.119
hum-5Protein HUM-50.115
his-62Protein HIS-620.112
rad-26Protein RAD-260.111
tag-319Protein TAG-3190.110
zip-7Protein ZIP-70.110
cfim-2Protein CFIM-20.109
his-68Protein HIS-680.108
Y48E1A.1Protein Y48E1A.10.104
lin-66Protein LIN-660.103
egl-13Protein EGL-130.103
ztf-2Protein ZTF-20.102
his-63Protein HIS-630.099
lin-12Protein LIN-120.098
CELE_C24H12.5Protein C24H12.50.098
aph-2Protein APH-20.098
his-31Protein HIS-310.097
mtk-1Protein MTK-10.097
top-2Protein TOP-20.097
sna-2Protein SNA-20.096
F46G10.2Protein F46G10.20.096
his-72Protein HIS-720.095
set-2Protein SET-20.094
daf-1Protein DAF-10.094
swsn-4Protein SWSN-40.093
mcm-5Protein MCM-50.091
cdl-1Protein CDL-10.089
sur-2Protein SUR-20.089
unc-42Protein UNC-420.089
egl-38Protein EGL-380.087
Y65A5A.1Protein Y65A5A.10.087
acs-4Protein ACS-40.087
daf-4Protein DAF-40.085
hlh-2Protein HLH-20.085
mec-3Protein MEC-30.085
his-15Protein HIS-150.084
npp-22Protein NPP-220.084
his-52Protein HIS-520.083
lin-29Protein LIN-290.082
dcr-1Protein DCR-10.082
F42G9.1Protein F42G9.10.082
mep-1Protein MEP-10.081
cpf-2Protein CPF-20.081
CELE_F19F10.9Protein F19F10.90.081
mom-2Protein MOM-20.080
hlh-11Protein HLH-110.079
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
jag2jagged 20.832
dlx2adistal-less homeobox gene 2a0.806
ndr2nodal-related 20.758
gata6GATA-binding protein 60.701
chdchordin0.691
gli1GLI-Kruppel family member 10.673
snai1bsnail homolog 1b (Drosophila)0.663
foxa3forkhead box A30.645
aldh1a2aldehyde dehydrogenase 1 family, member A20.598
wnt5bwingless-type MMTV integration site family, member 5b0.544
pcnaproliferating cell nuclear antigen0.518
twist3twist30.504
otx1borthodenticle homolog 1b0.483
pitx2paired-like homeodomain transcription factor 20.477
whsc1Wolf-Hirschhorn syndrome candidate 10.431
nkx2.5NK2 transcription factor related 50.405
mab21l2mab-21-like 20.396
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.385
zic1zic family member 1 (odd-paired homolog, Drosophila)0.380
dlx5adistal-less homeobox gene 5a0.372
vsx2visual system homeobox 20.358
nr2e1nuclear receptor subfamily 2, group E, member 10.357
vsx1visual system homeobox 1 homolog, chx10-like0.345
hoxc4ahomeo box C4a0.341
sox10SRY-box containing gene 100.326
sox19aSRY-box containing gene 19a0.318
snai1asnail homolog 1a (Drosophila)0.316
ascl1aachaete-scute complex-like 1a (Drosophila)0.297
lhx5LIM homeobox 50.292
her1hairy-related 10.288
gro1groucho 10.284
hmx1H6 homeo box 10.281
bmp4bone morphogenetic protein 40.276
sox9bSRY-box containing gene 9b0.272
wnt1wingless-type MMTV integration site family, member 10.272
pax8paired box gene 80.270
rx3retinal homeobox gene 30.253
tbx6T-box gene 60.252
gpiaglucose phosphate isomerase a0.251
lhx1aLIM homeobox 1a0.242
flhfloating head0.241
ripply1ripply10.240
fgf3fibroblast growth factor 30.239
ptf1apancreas specific transcription factor, 1a0.235
gscgoosecoid0.235
hoxb1bhomeo box B1b0.232
bmp2bbone morphogenetic protein 2b0.223
ef1aelongation factor 1-alpha0.221
pax6apaired box gene 6a0.217
tll1tolloid-like 10.215
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.211
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.208
dctdopachrome tautomerase0.207
her15.1hairy and enhancer of split-related 15.10.206
hp1bp3heterochromatin protein 1, binding protein 30.205
spawsouthpaw0.199
alcamaactivated leukocyte cell adhesion molecule a0.198
sesn1sestrin 10.192
dusp6dual specificity phosphatase 60.190
msxcmuscle segment homeobox C0.187
dlx3bdistal-less homeobox gene 3b0.183
gbx2gastrulation brain homeo box 20.179
nkx2.1bNK2 homeobox 1b0.178
eomesaeomesodermin homolog a0.178
meis2.1myeloid ecotropic viral integration site 2.10.175
tcf7transcription factor 7 (T-cell specific, HMG-box)0.175
fgf19fibroblast growth factor 190.172
esr2aestrogen receptor 2a0.172
axin2axin 2 (conductin, axil)0.167
msgn1mesogenin 10.166
thrbthyroid hormone receptor beta0.166
nog2noggin 20.166
dlcdeltaC0.165
evx1even-skipped homeobox 10.165
eng1aengrailed 1a0.162
prdm14PR domain containing 140.159
meis3myeloid ecotropic viral integration site 30.157
hnf1baHNF1 homeobox Ba0.156
pnxposterior neuron-specific homeobox0.154
per2period homolog 2 (Drosophila)0.154
satb2SATB homeobox 20.152
foxp1bforkhead box P1b0.152
ola1Obg-like ATPase 10.152
zic5zic family member 5 (odd-paired homolog, Drosophila)0.145
dkk1bdickkopf 1b0.143
wt1awilms tumor 1a0.139
plagl2pleiomorphic adenoma gene-like 20.138
fzd8afrizzled homolog 8a0.137
lmx1b.1LIM homeobox transcription factor 1, beta 10.134
khdrbs1aKH domain containing, RNA binding, signal transduction associated 1a0.133
wif1wnt inhibitory factor 10.130
pou1f1POU domain, class 1, transcription factor 10.130
gcm2glial cells missing homolog 2 (Drosophila)0.129
rxrbbretinoid x receptor, beta b0.129
kctd15apotassium channel tetramerisation domain containing 15a0.128
sp7Sp7 transcription factor0.127
emx1empty spiracles homeobox 10.127
dlddeltaD0.127
shhasonic hedgehog a0.124
tbx16T-box gene 160.123
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Snr1Snf5-related 10.999
hephemipterous0.999
cicubitus interruptus0.998
PclPolycomblike0.998
E(spl)Enhancer of split0.998
E(z)Enhancer of zeste0.996
CTCFCG8591 gene product from transcript CG8591-RA0.988
gppgrappa0.984
spensplit ends0.982
atoatonal0.981
panpangolin0.978
phylphyllopod0.973
Rpd3CG7471 gene product from transcript CG7471-RA0.971
Sir2CG5216 gene product from transcript CG5216-RA0.968
ash1absent, small, or homeotic discs 10.960
grogroucho0.958
NNotch0.956
D1D1 chromosomal protein0.954
mirrmirror0.952
dcodiscs overgrown0.950
mammastermind0.948
gsbgooseberry0.948
brkbrinker0.946
ssspineless0.945
ScmSex comb on midleg0.945
MadMothers against dpp0.939
mrnmarionette0.931
IswiImitation SWI0.930
kaykayak0.918
hthhomothorax0.916
smt3CG4494 gene product from transcript CG4494-RA0.915
waplwings apart-like0.911
Mob2CG11711 gene product from transcript CG11711-RC0.909
PtenCG5671 gene product from transcript CG5671-RB0.900
trxtrithorax0.891
araaraucan0.891
Kr-h1Kruppel homolog 10.885
eggeggless0.880
ykiyorkie0.879
crmcramped0.878
UbxUltrabithorax0.873
tlltailless0.867
Taf1TBP-associated factor 10.867
hbhunchback0.863
pdm2POU domain protein 20.850
tintinman0.848
hkbhuckebein0.847
shnschnurri0.843
HLHmdeltaE(spl) region transcript mdelta0.842
escextra sexcombs0.839
eygeyegone0.836
osaCG7467 gene product from transcript CG7467-RD0.834
Su(H)Suppressor of Hairless0.831
linlines0.831
slp1sloppy paired 10.826
pbproboscipedia0.825
snasnail0.817
RgaRegena0.816
nocno ocelli0.815
bratbrain tumor0.812
AntpAntennapedia0.809
Jarid2CG3654 gene product from transcript CG3654-RD0.804
abd-Aabdominal A0.804
alaristaless0.797
sxcsuper sex combs0.794
simsingle-minded0.792
garzgartenzwerg0.788
bowlbrother of odd with entrails limited0.787
PcPolycomb0.787
enengrailed0.784
barrbarren0.780
stysprouty0.768
kluklumpfuss0.762
scascabrous0.762
Src42ASrc oncogene at 42A0.760
Acf1ATP-dependent chromatin assembly factor large subunit0.760
ushu-shaped0.749
kniknirps0.734
SceSex combs extra0.734
nubnubbin0.733
Doc2Dorsocross20.732
CtBPC-terminal Binding Protein0.732
InRInsulin-like receptor0.732
prdpaired0.723
RbfRetinoblastoma-family protein0.721
howheld out wings0.718
Tip60CG6121 gene product from transcript CG6121-RA0.717
emsempty spiracles0.712
ecdecdysoneless0.710
SoxNSoxNeuro0.708
osoutstretched0.707
nejnejire0.705
DrefDNA replication-related element factor0.705
opaodd paired0.705
HLHmbetaE(spl) region transcript mbeta0.702
DpDP transcription factor0.697
knknot0.695
nkdnaked cuticle0.694
E(var)3-9Enhancer of variegation 3-90.691
esgescargot0.677
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
HHT1Hht1p0.996
RPD3Rpd3p0.995
RAP1Rap1p0.995
HHF1Hhf1p0.993
SIR2Sir2p0.989
RXT2Rxt2p0.967
RLF2Rlf2p0.964
HDA1Hda1p0.959
ISW2Isw2p0.956
SIN3Sin3p0.949
ORC2Orc2p0.944
SDS3Sds3p0.940
SUM1Sum1p0.935
SIR4Sir4p0.931
PHO23Pho23p0.931
SIN4Sin4p0.929
RCO1Rco1p0.918
SET1Set1p0.915
SET2Set2p0.905
SNF1Snf1p0.893
ORC5Orc5p0.887
RIM101Rim101p0.887
SIR3Sir3p0.879
EAF3Eaf3p0.879
CTI6Cti6p0.878
RIF1Rif1p0.867
FKH2Fkh2p0.856
RPN4Rpn4p0.848
HDA3Hda3p0.837
GAL11Gal11p0.822
SET3Set3p0.822
SSN3Ssn3p0.799
CYC8Cyc8p0.798
UBP8Ubp8p0.786
PAP2Pap2p0.785
HAT1Hat1p0.784
SPT21Spt21p0.783
RGR1Rgr1p0.755
PGD1Pgd1p0.747
HTZ1Htz1p0.743
DOA1Doa1p0.710
CDC6Cdc6p0.708
SLX5Slx5p0.705
SRP1Srp1p0.695
SAS2Sas2p0.690
CKA2Cka2p0.689
IFH1Ifh1p0.687
RTT106Rtt106p0.682
HMO1Hmo1p0.682
NHP6ANhp6ap0.676
ESA1Esa1p0.666
NAT1Nat1p0.662
GLN3Gln3p0.661
RSC4Rsc4p0.661
GCR2Gcr2p0.655
CSE2Cse2p0.648
SNT1Snt1p0.643
DEP1Dep1p0.638
MET4Met4p0.637
GCN5Gcn5p0.631
HOG1Hog1p0.628
STH1Sth1p0.620
ASF1Asf1p0.608
SPT16Spt16p0.603
SPT10Spt10p0.599
UME1Ume1p0.586
BMH2Bmh2p0.582
IZH4Izh4p0.579
IXR1Ixr1p0.564
CTF18Ctf18p0.553
MED2Med2p0.552
RIM20Rim20p0.550
FOB1Fob1p0.550
SWI4Swi4p0.543
HAA1Haa1p0.539
IES3Ies3p0.537
SCH9Sch9p0.532
HTB1Htb1p0.528
YSC84Ysc84p0.525
ROX3Rox3p0.520
REG1Reg1p0.515
ORC6Orc6p0.513
HIR1Hir1p0.511
ACT1Act1p0.489
CDC14Cdc14p0.489
NRG1Nrg1p0.477
YTA7Yta7p0.476
SAS4Sas4p0.473
PHO4Pho4p0.464
ADR1Adr1p0.464
YAK1Yak1p0.455
HAT2Hat2p0.453
HCM1Hcm1p0.452
MCM2Mcm2p0.450
FKH1Fkh1p0.450
SLX8Slx8p0.446
CTK1Ctk1p0.438
SNF5Snf5p0.435
HHF2Hhf2p0.435
BMH1Bmh1p0.429