The network for 'endocytic recycling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

endocytic recycling

The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport.

NameDescriptionProbabilityFunc Analog Organism
Psmb4proteasome (prosome, macropain) subunit, beta type 40.035
Psmb1proteasome (prosome, macropain) subunit, beta type 10.030
Atp5lATP synthase, H+ transporting, mitochondrial F0 complex, subunit G0.023
Cox6a1cytochrome c oxidase, subunit VIa, polypeptide 10.022
Tceb2transcription elongation factor B (SIII), polypeptide 20.021
Rpl36alribosomal protein L36a-like0.018
Cox5bcytochrome c oxidase subunit Vb0.017
LOC301124hypothetical LOC3011240.017
Ndufb9NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 90.017
Atp5oATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.017
Psmb3proteasome (prosome, macropain) subunit, beta type 30.016
Cox7a2cytochrome c oxidase subunit VIIa polypeptide 20.016
Ndufb5NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 50.016
Timm13translocase of inner mitochondrial membrane 13 homolog (yeast)0.015
RGD1306917similar to RIKEN cDNA 2900010M230.015
RGD1304704similar to Hypothetical protein CGI-990.015
Rpl18ribosomal protein L180.014
Uqcr11ubiquinol-cytochrome c reductase, complex III subunit XI0.014
Pompproteasome maturation protein0.014
Ndufa13NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 130.014
Tomm6translocase of outer mitochondrial membrane 6 homolog (yeast)0.014
Ndufb10NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 100.014
Atp5hATP synthase, H+ transporting, mitochondrial F0 complex, subunit d0.013
Psma2proteasome (prosome, macropain) subunit, alpha type 20.013
Chchd2coiled-coil-helix-coiled-coil-helix domain containing 20.013
Cyc1cytochrome c-10.013
Uqcrqubiquinol-cytochrome c reductase, complex III subunit VII0.013
Tmed2transmembrane emp24 domain trafficking protein 20.013
Cox7ccytochrome c oxidase, subunit VIIc0.013
Nme2non-metastatic cells 2, protein (NM23B) expressed in0.013
LOC688869similar to cytochrome c oxidase, subunit VIb polypeptide 10.013
Atp5c1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.013
Rps11ribosomal protein S110.012
Hspe1heat shock protein 1 (chaperonin 10)0.012
Tomm20translocase of outer mitochondrial membrane 20 homolog (yeast)0.012
Cct3chaperonin containing Tcp1, subunit 3 (gamma)0.012
Ndufa2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 20.012
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.012
Eif3ieukaryotic translation initiation factor 3, subunit I0.012
Lsmd1LSM domain containing 10.012
Psmb6proteasome (prosome, macropain) subunit, beta type 60.012
Ndufb2NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 20.012
Uba52ubiquitin A-52 residue ribosomal protein fusion product 10.012
Atp5eATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit0.012
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.011
Atp5j2ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F20.011
LOC100363539mitochondrial ribosomal protein L33-like0.011
LOC100359498ribosomal protein L35a-like0.011
Ssr4signal sequence receptor, delta0.011
Rpl10aribosomal protein L10A0.011
Ndufa11NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 110.011
Mrps7mitochondrial ribosomal protein S70.011
Hnrnpa3heterogeneous nuclear ribonucleoprotein A30.011
Atp5dATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit0.011
Rpl11ribosomal protein L110.011
Mrpl27mitochondrial ribosomal protein L270.011
Mrpl20mitochondrial ribosomal protein L200.011
Timm8btranslocase of inner mitochondrial membrane 8 homolog b (yeast)0.011
Grpel1GrpE-like 1, mitochondrial0.011
Caprin1cell cycle associated protein 10.010
Park7Parkinson disease (autosomal recessive, early onset) 70.010
Rps5ribosomal protein S50.010
Rpl15ribosomal protein L150.010
Psma7proteasome (prosome, macropain) subunit, alpha type 70.010
Atp6v1fATPase, H transporting, lysosomal V1 subunit F0.010
Psmd8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rab1Rab-protein 10.127
sec6CG5341 gene product from transcript CG5341-RA0.090
matsmob as tumor suppressor0.054
Rab11Rab-protein 110.047
Rab2Rab-protein 20.042
didumdilute class unconventional myosin0.037
bip2CG2009 gene product from transcript CG2009-RA0.036
KlcKinesin light chain0.035
CG4567CG4567 gene product from transcript CG4567-RA0.033
Tab2TAK1-associated binding protein 20.030
Vps16AVacuolar protein sorting 16A0.027
sec8CG2095 gene product from transcript CG2095-RA0.024
Npc1aNiemann-Pick type C-1a0.021
RalaRas-related protein0.020
DlicDynein light intermediate chain0.020
BG4CG12297 gene product from transcript CG12297-RA0.019
CanB2Calcineurin B20.017
AckCG14992 gene product from transcript CG14992-RA0.016
nudECG8104 gene product from transcript CG8104-RB0.015
AGO2Argonaute 20.015
Rab7Rab-protein 70.014
MadmMLF1-adaptor molecule0.013
RagACG11968 gene product from transcript CG11968-RA0.013
sec5CG8843 gene product from transcript CG8843-RA0.013
l(1)G0144lethal (1) G01440.012
KhcKinesin heavy chain0.012
tacctransforming acidic coiled-coil protein0.011
Ubc-E2HCG2257 gene product from transcript CG2257-RA0.011
RhebCG1081 gene product from transcript CG1081-RA0.011
swshort wing0.011
IlkIntegrin linked kinase0.011
Atg6Autophagy-specific gene 60.010
Hip14Huntingtin-interacting protein 140.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GGA2golgi-associated, gamma adaptin ear containing, ARF binding protein 20.853
SYNRGsynergin, gamma0.772
TBK1TANK-binding kinase 10.530
RABEP1rabaptin, RAB GTPase binding effector protein 10.518
AP2B1adaptor-related protein complex 2, beta 1 subunit0.491
UBR1ubiquitin protein ligase E3 component n-recognin 10.421
CYLDcylindromatosis (turban tumor syndrome)0.398
EHD1EH-domain containing 10.353
PDPK13-phosphoinositide dependent protein kinase-10.330
GGA1golgi-associated, gamma adaptin ear containing, ARF binding protein 10.210
GDI2GDP dissociation inhibitor 20.206
AZI25-azacytidine induced 20.198
OCRLoculocerebrorenal syndrome of Lowe0.191
TANKTRAF family member-associated NFKB activator0.167
SYKspleen tyrosine kinase0.164
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.158
UBR3ubiquitin protein ligase E3 component n-recognin 3 (putative)0.156
LDOC1leucine zipper, down-regulated in cancer 10.150
RPTORregulatory associated protein of MTOR, complex 10.150
AP1G1adaptor-related protein complex 1, gamma 1 subunit0.130
TRAF2TNF receptor-associated factor 20.123
RAB1ARAB1A, member RAS oncogene family0.120
SCHIP1schwannomin interacting protein 10.117
AP2A1adaptor-related protein complex 2, alpha 1 subunit0.109
RAB11ARAB11A, member RAS oncogene family0.108
FADS2fatty acid desaturase 20.092
GOLGA2golgin A20.080
SORT1sortilin 10.077
ATF2activating transcription factor 20.076
SORL1sortilin-related receptor, L(DLR class) A repeats containing0.075
RAD18RAD18 homolog (S. cerevisiae)0.068
RAB8ARAB8A, member RAS oncogene family0.067
AP2M1adaptor-related protein complex 2, mu 1 subunit0.063
ANKFY1ankyrin repeat and FYVE domain containing 10.061
UBE2Aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.060
MTF1metal-regulatory transcription factor 10.059
EXOC4exocyst complex component 40.058
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.058
PPP1R2protein phosphatase 1, regulatory (inhibitor) subunit 20.055
INPP5Dinositol polyphosphate-5-phosphatase, 145kDa0.052
RAB5ARAB5A, member RAS oncogene family0.051
IRF3interferon regulatory factor 30.050
TBKBP1TBK1 binding protein 10.049
RAB10RAB10, member RAS oncogene family0.048
MICALL1MICAL-like 10.047
IGF2Rinsulin-like growth factor 2 receptor0.045
PREX1phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 10.045
DHCR77-dehydrocholesterol reductase0.044
LAMTOR3late endosomal/lysosomal adaptor, MAPK and MTOR activator 30.042
EPS15epidermal growth factor receptor pathway substrate 150.031
UBASH3Bubiquitin associated and SH3 domain containing B0.031
PPP1CCprotein phosphatase 1, catalytic subunit, gamma isozyme0.029
TBC1D17TBC1 domain family, member 170.028
MAP3K7mitogen-activated protein kinase kinase kinase 70.026
MAPK8IP3mitogen-activated protein kinase 8 interacting protein 30.025
RNF11ring finger protein 110.024
NUDT3nudix (nucleoside diphosphate linked moiety X)-type motif 30.024
EEA1early endosome antigen 10.023
SPG21spastic paraplegia 21 (autosomal recessive, Mast syndrome)0.022
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.021
HGShepatocyte growth factor-regulated tyrosine kinase substrate0.020
UBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)0.020
CLTCclathrin, heavy chain (Hc)0.019
SPHARS-phase response (cyclin related)0.018
M6PRmannose-6-phosphate receptor (cation dependent)0.018
IL4Rinterleukin 4 receptor0.018
PTRFpolymerase I and transcript release factor0.017
UBE2G1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.016
SNX6sorting nexin 60.016
FXR2fragile X mental retardation, autosomal homolog 20.015
SCDstearoyl-CoA desaturase (delta-9-desaturase)0.015
GNA13guanine nucleotide binding protein (G protein), alpha 130.015
RAB14RAB14, member RAS oncogene family0.015
BIN1bridging integrator 10.014
MAP7D1MAP7 domain containing 10.014
TRIM23tripartite motif containing 230.013
AGFG1ArfGAP with FG repeats 10.013
PPP1CBprotein phosphatase 1, catalytic subunit, beta isozyme0.013
EHD4EH-domain containing 40.013
RAB11FIP1RAB11 family interacting protein 1 (class I)0.012
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.012
AP1B1adaptor-related protein complex 1, beta 1 subunit0.012
TIFATRAF-interacting protein with forkhead-associated domain0.012
STON2stonin 20.011
DEPTORDEP domain containing MTOR-interacting protein0.011
FCHO2FCH domain only 20.011
TNIP1TNFAIP3 interacting protein 10.011
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.010
YTHDF3YTH domain family, member 30.010
TRAF3TNF receptor-associated factor 30.010
BLNKB-cell linker0.010
ARF6ADP-ribosylation factor 60.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.034
Rab11aRAB11a, member RAS oncogene family0.025
RictorRPTOR independent companion of MTOR, complex 20.017
Tsc1tuberous sclerosis 10.015
Bcl2B-cell leukemia/lymphoma 20.015
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.015
Mapkap1mitogen-activated protein kinase associated protein 10.013
TankTRAF family member-associated Nf-kappa B activator0.012
Ctnna1catenin (cadherin associated protein), alpha 10.011
Rptorregulatory associated protein of MTOR, complex 10.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism