The network for 'leydig cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

leydig cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.

NameDescriptionProbabilityFunc Analog Organism
Prdx1peroxiredoxin 10.627
DdtD-dopachrome tautomerase0.379
Ddr2discoidin domain receptor tyrosine kinase 20.274
Dbidiazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)0.202
Decr12,4-dienoyl CoA reductase 1, mitochondrial0.174
Akr1c18aldo-keto reductase family 1, member C180.171
Gsta3glutathione S-transferase A30.162
Etfbelectron-transfer-flavoprotein, beta polypeptide0.157
Mettl7bmethyltransferase like 7B0.156
Gsta4glutathione S-transferase alpha 40.144
Scnn1gsodium channel, nonvoltage-gated 1, gamma0.139
Starsteroidogenic acute regulatory protein0.136
Hsd3b1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 10.131
Slc13a2solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 20.122
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.114
Ralav-ral simian leukemia viral oncogene homolog A (ras related)0.113
Hes2hairy and enhancer of split 2 (Drosophila)0.098
Tff2trefoil factor 20.087
Naglt1Na+ dependent glucose transporter 10.086
Ephx1epoxide hydrolase 1, microsomal0.084
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.080
Lama2laminin, alpha 20.078
Nr5a2nuclear receptor subfamily 5, group A, member 20.069
Rln1relaxin 10.069
Scp2sterol carrier protein 20.069
Pla2g5phospholipase A2, group V0.067
Lhcgrluteinizing hormone/choriogonadotropin receptor0.064
Krt34keratin 340.064
Mamdc4MAM domain containing 40.060
Cyb5acytochrome b5 type A (microsomal)0.054
Gabrg3gamma-aminobutyric acid (GABA) A receptor, gamma 30.054
Slc22a25solute carrier family 22, member 250.052
Mosc2MOCO sulphurase C-terminal domain containing 20.051
Echs1enoyl Coenzyme A hydratase, short chain, 1, mitochondrial0.050
Slc9a4solute carrier family 9 (sodium/hydrogen exchanger), member 40.049
Atxn1ataxin 10.046
Hrh2histamine receptor H 20.045
Cela2achymotrypsin-like elastase family, member 2A0.042
Defb4defensin beta 40.041
Prl7d1prolactin family 7, subfamily d, member 10.041
Apobapolipoprotein B0.039
Gjb3gap junction protein, beta 30.039
Hpd4-hydroxyphenylpyruvate dioxygenase0.039
Sod1superoxide dismutase 1, soluble0.039
Acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.039
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.038
Prss3protease, serine, 30.038
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.036
Capn9calpain 90.035
Galnt5UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)0.035
Lamp2lysosomal-associated membrane protein 20.033
LOC691807hypothetical protein LOC6918070.033
Vom1r97vomeronasal 1 receptor 970.032
RGD1304731similar to RIKEN cDNA 5330437I02 gene0.031
AxlAxl receptor tyrosine kinase0.030
Zfp36l1zinc finger protein 36, C3H type-like 10.029
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.029
Wipf1WAS/WASL interacting protein family, member 10.029
Aqp8aquaporin 80.029
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.029
Cyp17a1cytochrome P450, family 17, subfamily a, polypeptide 10.029
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.028
Grik3glutamate receptor, ionotropic, kainate 30.028
Pla2g1bphospholipase A2, group IB, pancreas0.027
Itga1integrin, alpha 10.027
Gpx1glutathione peroxidase 10.026
Bdh23-hydroxybutyrate dehydrogenase, type 20.025
Gstp1glutathione S-transferase pi 10.025
Col10a1collagen, type X, alpha 10.025
Prlrprolactin receptor0.024
Fkbp9FK506 binding protein 90.024
Akap4A kinase (PRKA) anchor protein 40.024
Fcer1aFc fragment of IgE, high affinity I, receptor for; alpha polypeptide0.024
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.024
Cst12cystatin 120.024
Crisp2cysteine-rich secretory protein 20.024
Chrna3cholinergic receptor, nicotinic, alpha 30.023
Naaladl1N-acetylated alpha-linked acidic dipeptidase-like 10.023
Sdc1syndecan 10.023
Olr1867olfactory receptor 18670.022
Sdhcsuccinate dehydrogenase complex, subunit C, integral membrane protein0.022
Cox16COX16 cytochrome c oxidase assembly homolog0.022
Nrp1neuropilin 10.022
Dpep1dipeptidase 1 (renal)0.022
Nos1nitric oxide synthase 1, neuronal0.022
FaslgFas ligand (TNF superfamily, member 6)0.021
Sult1a1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 10.021
Robld3roadblock domain containing 30.021
Acaa2acetyl-Coenzyme A acyltransferase 20.021
Calcrcalcitonin receptor0.021
Prm3protamine 30.021
Cyp2d4cytochrome P450, family 2, subfamily d, polypeptide 40.021
Ech1enoyl coenzyme A hydratase 1, peroxisomal0.021
Acat3acetyl-Coenzyme A acetyltransferase 30.021
Tacr2tachykinin receptor 20.020
Idh1isocitrate dehydrogenase 1 (NADP+), soluble0.020
Bcap31B-cell receptor-associated protein 310.020
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.020
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 20.996
Sox9SRY-box containing gene 90.972
Lhcgrluteinizing hormone/choriogonadotropin receptor0.955
Nr5a1nuclear receptor subfamily 5, group A, member 10.936
Amhr2anti-Mullerian hormone type 2 receptor0.756
Ctnnb1catenin (cadherin associated protein), beta 10.704
Hand1heart and neural crest derivatives expressed transcript 10.693
Hand2heart and neural crest derivatives expressed transcript 20.686
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.675
Esr1estrogen receptor 1 (alpha)0.665
Shhsonic hedgehog0.649
Trp53transformation related protein 530.609
TiparpTCDD-inducible poly(ADP-ribose) polymerase0.581
Sall4sal-like 4 (Drosophila)0.518
Arandrogen receptor0.398
Pthlhparathyroid hormone-like peptide0.355
Fgfr3fibroblast growth factor receptor 30.350
Cdkn1bcyclin-dependent kinase inhibitor 1B0.333
Csf1colony stimulating factor 1 (macrophage)0.326
Kiss1KiSS-1 metastasis-suppressor0.311
Apcadenomatosis polyposis coli0.309
Tcf21transcription factor 210.303
Gli3GLI-Kruppel family member GLI30.295
Foxc2forkhead box C20.295
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.292
Gli2GLI-Kruppel family member GLI20.281
Bmp2bone morphogenetic protein 20.280
Ptenphosphatase and tensin homolog0.248
Dhhdesert hedgehog0.242
Fshrfollicle stimulating hormone receptor0.238
Vegfavascular endothelial growth factor A0.202
Fgf9fibroblast growth factor 90.196
Ptch1patched homolog 10.192
Ror2receptor tyrosine kinase-like orphan receptor 20.170
Foxc1forkhead box C10.166
Nkx3-2NK3 homeobox 20.163
Runx2runt related transcription factor 20.158
Pax8paired box gene 80.150
Nr0b1nuclear receptor subfamily 0, group B, member 10.141
Amhanti-Mullerian hormone0.130
Cdk4cyclin-dependent kinase 40.129
WwoxWW domain-containing oxidoreductase0.129
Hoxd3homeobox D30.127
Meox2mesenchyme homeobox 20.123
Tcirg1T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A30.122
Pdx1pancreatic and duodenal homeobox 10.104
Hoxa10homeobox A100.103
Gata4GATA binding protein 40.097
Schip1schwannomin interacting protein 10.096
Zeb1zinc finger E-box binding homeobox 10.093
Hoxd11homeobox D110.091
Nkx6-1NK6 homeobox 10.089
Pou5f1POU domain, class 5, transcription factor 10.085
Bmp4bone morphogenetic protein 40.084
Pcsk5proprotein convertase subtilisin/kexin type 50.082
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.081
Foxa2forkhead box A20.080
Hes3hairy and enhancer of split 3 (Drosophila)0.079
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.072
Smosmoothened homolog (Drosophila)0.072
Col2a1collagen, type II, alpha 10.071
Gata6GATA binding protein 60.070
Esr2estrogen receptor 2 (beta)0.067
Tgfbr2transforming growth factor, beta receptor II0.060
Fgf8fibroblast growth factor 80.060
Plekha5pleckstrin homology domain containing, family A member 50.057
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.057
Pgrprogesterone receptor0.057
Tbx3T-box 30.056
Ahraryl-hydrocarbon receptor0.056
Kdrkinase insert domain protein receptor0.055
Hnf4ahepatic nuclear factor 4, alpha0.054
Rspo2R-spondin 2 homolog (Xenopus laevis)0.052
Nr1i3nuclear receptor subfamily 1, group I, member 30.051
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.049
Esx1extraembryonic, spermatogenesis, homeobox 10.048
Nkx3-1NK-3 transcription factor, locus 1 (Drosophila)0.048
Ptprbprotein tyrosine phosphatase, receptor type, B0.047
Tbx1T-box 10.046
Cdk6cyclin-dependent kinase 60.046
Prlrprolactin receptor0.046
Otporthopedia homolog (Drosophila)0.043
CblCasitas B-lineage lymphoma0.043
Hsd3b1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 10.043
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.041
Cdh5cadherin 50.039
Hoxd13homeobox D130.039
Ldlrlow density lipoprotein receptor0.038
Sall1sal-like 1 (Drosophila)0.037
Nf1neurofibromatosis 10.036
Starsteroidogenic acute regulatory protein0.035
Fgf10fibroblast growth factor 100.034
Drd2dopamine receptor D20.034
Tnp1transition protein 10.033
Foxb2forkhead box B20.033
Pitx1paired-like homeodomain transcription factor 10.031
Pax3paired box gene 30.030
Foxe1forkhead box E10.030
Gnrh1gonadotropin releasing hormone 10.029
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism