The network for 't cell tolerance induction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

t cell tolerance induction

A process involving any mechanism for tolerance induction in T cells.

NameDescriptionProbabilityFunc Analog Organism
RT1-EC2RT1 class Ib, locus EC21.000
RT1-S3RT1 class Ib, locus S30.703
Oas1a2'-5' oligoadenylate synthetase 1A0.691
RT1-CE12RT1 class I, locus CE120.629
LOC100364500RT1 class I, locus CE11-like0.608
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.535
B2mbeta-2 microglobulin0.354
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.268
Dock8dedicator of cytokinesis 80.240
RT1-M3-1RT1 class Ib, locus M3, gene 10.209
Cybbcytochrome b-245, beta polypeptide0.185
Ifi35interferon-induced protein 350.152
RT1-N3RT1 class Ib, locus N30.137
Lgals3bplectin, galactoside-binding, soluble, 3 binding protein0.130
Cd4Cd4 molecule0.125
Yy1YY1 transcription factor0.120
Slco2b1solute carrier organic anion transporter family, member 2b10.115
Apol3apolipoprotein L, 30.111
Hnf4ahepatocyte nuclear factor 4, alpha0.110
Tap1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.101
Cxcl9chemokine (C-X-C motif) ligand 90.101
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.097
Cd38CD38 molecule0.092
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.091
Capn5calpain 50.086
Fgfr2fibroblast growth factor receptor 20.085
RT1-CE5RT1 class I, locus CE50.081
Calcrlcalcitonin receptor-like0.080
Casp1caspase 10.079
LOC246267resection-induced TPI (rs11)0.078
Mmp12matrix metallopeptidase 120.077
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.077
Ifi27interferon, alpha-inducible protein 270.076
Il1r1interleukin 1 receptor, type I0.072
RT1-ClRT1 class Ib, locus Cl0.070
Mx1myxovirus (influenza virus) resistance 10.067
Cxcl10chemokine (C-X-C motif) ligand 100.061
RT1-A3RT1 class I, locus A30.061
Tas1r3taste receptor, type 1, member 30.060
Metmet proto-oncogene0.056
Ctshcathepsin H0.054
RGD1305793similar to hypothetical protein FLJ201540.051
Man2b1mannosidase, alpha, class 2B, member 10.049
Rtp4receptor (chemosensory) transporter protein 40.048
Irf7interferon regulatory factor 70.046
Mpeg1macrophage expressed 10.046
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.046
Ahraryl hydrocarbon receptor0.046
Irf1interferon regulatory factor 10.045
Pld1phospholipase D10.042
LOC100364352cytochrome P450, family 2, subfamily b, polypeptide 9-like0.040
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.039
Gbp2guanylate binding protein 20.039
Foxc2forkhead box C20.039
Tgfbr2transforming growth factor, beta receptor II0.038
Ephx1epoxide hydrolase 1, microsomal0.037
Lcklymphocyte-specific protein tyrosine kinase0.037
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.037
Il7interleukin 70.037
Cybacytochrome b-245, alpha polypeptide0.037
Lgals5lectin, galactose binding, soluble 50.037
Adora3adenosine A3 receptor0.036
Aif1allograft inflammatory factor 10.035
Lgals9lectin, galactoside-binding, soluble, 90.035
Arnt2aryl hydrocarbon receptor nuclear translocator 20.034
Ccl5chemokine (C-C motif) ligand 50.034
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.033
Anpepalanyl (membrane) aminopeptidase0.033
Ptch1patched homolog 1 (Drosophila)0.032
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.032
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.031
Tbxa2rthromboxane A2 receptor0.031
Cst8cystatin 8 (cystatin-related epididymal specific)0.031
Dnase1l3deoxyribonuclease 1-like 30.031
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.031
Olr1082olfactory receptor 10820.030
C2complement component 20.030
Ednraendothelin receptor type A0.030
Myo1amyosin IA0.030
Bmp6bone morphogenetic protein 60.029
Akr1c14aldo-keto reductase family 1, member C140.029
TapbpTAP binding protein0.029
Galmgalactose mutarotase (aldose 1-epimerase)0.029
Batf3basic leucine zipper transcription factor, ATF-like 30.028
Cd247Cd247 molecule0.028
Olr837olfactory receptor 8370.028
Gpr116G protein-coupled receptor 1160.028
P2ry12purinergic receptor P2Y, G-protein coupled, 120.027
Olr1346olfactory receptor 13460.027
Gbp5guanylate binding protein 50.027
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.027
RT1-M6-2RT1 class I, locus M6, gene 20.027
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.026
Stat6signal transducer and activator of transcription 60.026
Lifrleukemia inhibitory factor receptor alpha0.026
Elf1E74-like factor 10.025
Gstm2glutathione S-transferase mu 20.025
RT1-CE2RT1 class I, locus CE20.025
Mr1major histocompatibility complex, class I-related0.024
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HLA-Gmajor histocompatibility complex, class I, G0.997
HLA-Amajor histocompatibility complex, class I, A0.997
HLA-Bmajor histocompatibility complex, class I, B0.996
HLA-Cmajor histocompatibility complex, class I, C0.992
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.967
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.917
HLA-Fmajor histocompatibility complex, class I, F0.879
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.834
PILRApaired immunoglobin-like type 2 receptor alpha0.730
PTPN6protein tyrosine phosphatase, non-receptor type 60.690
HLA-Emajor histocompatibility complex, class I, E0.567
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.463
SIGLEC7sialic acid binding Ig-like lectin 70.415
LILRB3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.292
LTAlymphotoxin alpha (TNF superfamily, member 1)0.239
TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.221
CTLA4cytotoxic T-lymphocyte-associated protein 40.209
IFITM2interferon induced transmembrane protein 2 (1-8D)0.151
LILRA2leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 20.116
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.099
TGFB1transforming growth factor, beta 10.098
HK3hexokinase 3 (white cell)0.083
PTAFRplatelet-activating factor receptor0.078
SLC15A3solute carrier family 15, member 30.065
TAPBPTAP binding protein (tapasin)0.052
TGFB3transforming growth factor, beta 30.051
AOAHacyloxyacyl hydrolase (neutrophil)0.048
TYMPthymidine phosphorylase0.046
FCN1ficolin (collagen/fibrinogen domain containing) 10.044
CD80CD80 molecule0.043
CD247CD247 molecule0.041
CCR1chemokine (C-C motif) receptor 10.039
SIRPB1signal-regulatory protein beta 10.039
CD300CCD300c molecule0.033
CA12carbonic anhydrase XII0.032
LILRA3leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 30.031
WIPI1WD repeat domain, phosphoinositide interacting 10.031
CFLARCASP8 and FADD-like apoptosis regulator0.031
TREM1triggering receptor expressed on myeloid cells 10.029
LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein0.029
IKZF3IKAROS family zinc finger 3 (Aiolos)0.026
CD33CD33 molecule0.026
HLA-DRB5major histocompatibility complex, class II, DR beta 50.026
LILRB4leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 40.025
NLRP3NLR family, pyrin domain containing 30.025
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.025
SNX9sorting nexin 90.025
SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin0.025
EMR1egf-like module containing, mucin-like, hormone receptor-like 10.025
SGK3serum/glucocorticoid regulated kinase family, member 30.024
FSTL1follistatin-like 10.024
TAPBPLTAP binding protein-like0.024
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.023
NOD2nucleotide-binding oligomerization domain containing 20.022
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.022
CD3GCD3g molecule, gamma (CD3-TCR complex)0.021
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.020
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.020
OS9osteosarcoma amplified 9, endoplasmic reticulum lectin0.020
FCARFc fragment of IgA, receptor for0.019
TPP1tripeptidyl peptidase I0.019
SNX18sorting nexin 180.019
CD86CD86 molecule0.018
SIGLEC9sialic acid binding Ig-like lectin 90.018
NCK2NCK adaptor protein 20.018
ASGR2asialoglycoprotein receptor 20.017
RASSF4Ras association (RalGDS/AF-6) domain family member 40.017
TLR8toll-like receptor 80.016
HCP5HLA complex P50.016
TMEM176Atransmembrane protein 176A0.016
LILRA5leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 50.016
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.015
PIK3R5phosphoinositide-3-kinase, regulatory subunit 50.015
TGFBR1transforming growth factor, beta receptor 10.015
FPR2formyl peptide receptor 20.015
TNFSF12-TNFSF13TNFSF12-TNFSF13 readthrough0.015
VSIG4V-set and immunoglobulin domain containing 40.015
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.014
PECAM1platelet/endothelial cell adhesion molecule0.014
MARCOmacrophage receptor with collagenous structure0.014
APOBRapolipoprotein B receptor0.014
SPI1spleen focus forming virus (SFFV) proviral integration oncogene spi10.014
DPEP2dipeptidase 20.013
RNASE3ribonuclease, RNase A family, 30.013
CST3cystatin C0.013
FOLR3folate receptor 3 (gamma)0.013
NEDD9neural precursor cell expressed, developmentally down-regulated 90.013
USP38ubiquitin specific peptidase 380.013
SIRPAsignal-regulatory protein alpha0.013
CASP5caspase 5, apoptosis-related cysteine peptidase0.013
BEST1bestrophin 10.013
SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.013
SIGLEC5sialic acid binding Ig-like lectin 50.012
P2RX4purinergic receptor P2X, ligand-gated ion channel, 40.012
EPORerythropoietin receptor0.012
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tgfbr1transforming growth factor, beta receptor I0.743
H2-D1histocompatibility 2, D region locus 10.492
Tgfbr2transforming growth factor, beta receptor II0.448
Apcadenomatosis polyposis coli0.380
Shc1src homology 2 domain-containing transforming protein C10.300
B2mbeta-2 microglobulin0.300
Smad4MAD homolog 4 (Drosophila)0.218
H2-Q7histocompatibility 2, Q region locus 70.172
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.142
Smad6MAD homolog 6 (Drosophila)0.142
Rac1RAS-related C3 botulinum substrate 10.132
Acvr1activin A receptor, type 10.123
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.079
Map3k7mitogen-activated protein kinase kinase kinase 70.072
Smad3MAD homolog 3 (Drosophila)0.069
Stat3signal transducer and activator of transcription 30.068
Ptpn11protein tyrosine phosphatase, non-receptor type 110.065
Cdh5cadherin 50.058
Latlinker for activation of T cells0.055
Cyldcylindromatosis (turban tumor syndrome)0.055
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.054
Ece1endothelin converting enzyme 10.053
Bmpr1abone morphogenetic protein receptor, type 1A0.050
Bptfbromodomain PHD finger transcription factor0.048
Rnf11ring finger protein 110.041
Grb10growth factor receptor bound protein 100.037
Tgfbr3transforming growth factor, beta receptor III0.037
Smad7MAD homolog 7 (Drosophila)0.034
ItkIL2-inducible T-cell kinase0.033
Efemp2epidermal growth factor-containing fibulin-like extracellular matrix protein 20.024
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.023
Prkg1protein kinase, cGMP-dependent, type I0.020
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.019
Il6stinterleukin 6 signal transducer0.019
Foxp2forkhead box P20.018
Cd28CD28 antigen0.018
Tgfb2transforming growth factor, beta 20.017
Atp7aATPase, Cu++ transporting, alpha polypeptide0.017
Cd6CD6 antigen0.016
Grb2growth factor receptor bound protein 20.016
Cd3eCD3 antigen, epsilon polypeptide0.016
FynFyn proto-oncogene0.015
Il2rginterleukin 2 receptor, gamma chain0.015
Cd8aCD8 antigen, alpha chain0.015
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.015
Irf1interferon regulatory factor 10.014
Foxp1forkhead box P10.014
Smad1MAD homolog 1 (Drosophila)0.014
Batfbasic leucine zipper transcription factor, ATF-like0.014
Tmem64transmembrane protein 640.013
Arandrogen receptor0.013
Cd8b1CD8 antigen, beta chain 10.013
Bmp2bone morphogenetic protein 20.013
TcraT-cell receptor alpha chain0.013
Nr5a1nuclear receptor subfamily 5, group A, member 10.012
Sox9SRY-box containing gene 90.012
H2-Q8histocompatibility 2, Q region locus 80.012
Cd19CD19 antigen0.012
Lcklymphocyte protein tyrosine kinase0.012
XiapX-linked inhibitor of apoptosis0.012
Kiss1KiSS-1 metastasis-suppressor0.012
Hipk3homeodomain interacting protein kinase 30.011
Il2rbinterleukin 2 receptor, beta chain0.011
CflarCASP8 and FADD-like apoptosis regulator0.011
Zap70zeta-chain (TCR) associated protein kinase0.011
Flt1FMS-like tyrosine kinase 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism