The network for 'negative regulation of calcium ion import' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of calcium ion import

Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.

NameDescriptionProbabilityFunc Analog Organism
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.316
Slc14a2solute carrier family 14 (urea transporter), member 20.156
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.099
Slco2b1solute carrier organic anion transporter family, member 2b10.091
St18suppression of tumorigenicity 180.083
Notch3Notch homolog 3 (Drosophila)0.068
Sdc3syndecan 30.067
Csf1colony stimulating factor 1 (macrophage)0.066
MrgprfMAS-related GPR, member F0.065
Eporerythropoietin receptor0.062
Slc8a3solute carrier family 8 (sodium/calcium exchanger), member 30.060
Il9rinterleukin 9 receptor0.058
Gzmkgranzyme K0.058
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.057
G6pcglucose-6-phosphatase, catalytic subunit0.056
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.056
Pecam1platelet/endothelial cell adhesion molecule 10.053
Dccdeleted in colorectal carcinoma0.052
Flt1FMS-related tyrosine kinase 10.047
Gja6gap junction protein, alpha 60.047
Gcnt3glucosaminyl (N-acetyl) transferase 3, mucin type0.047
Dsppdentin sialophosphoprotein0.047
Slc22a25solute carrier family 22, member 250.046
Hoxa1homeo box A10.046
Insrrinsulin receptor-related receptor0.044
Avpr1barginine vasopressin receptor 1B0.043
Lims1LIM and senescent cell antigen-like domains 10.042
Atp2a3ATPase, Ca++ transporting, ubiquitous0.042
Ednraendothelin receptor type A0.041
N5DNA binding protein N50.041
LOC286987hemiferrin, transferrin-like protein0.040
Grm8glutamate receptor, metabotropic 80.040
Olr1867olfactory receptor 18670.040
FaslgFas ligand (TNF superfamily, member 6)0.040
Drd3dopamine receptor D30.040
Slc6a11solute carrier family 6 (neurotransmitter transporter, GABA), member 110.038
Kcnc3potassium voltage gated channel, Shaw-related subfamily, member 30.038
Chrna7cholinergic receptor, nicotinic, alpha 70.038
Prm3protamine 30.038
Adam10ADAM metallopeptidase domain 100.038
Smgbneonatal submandibular gland protein B0.037
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.037
Grm6glutamate receptor, metabotropic 60.036
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.036
Kynukynureninase (L-kynurenine hydrolase)0.036
Hand1heart and neural crest derivatives expressed 10.036
Bcl2B-cell CLL/lymphoma 20.036
Wfdc6aWAP four-disulfide core domain 6A0.035
Slco1a1solute carrier organic anion transporter family, member 1a10.034
Gpr1G protein-coupled receptor 10.034
Teddm1transmembrane epididymal protein 10.034
Accn2amiloride-sensitive cation channel 2, neuronal0.034
Naaladl1N-acetylated alpha-linked acidic dipeptidase-like 10.034
Grin2cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.033
Cela2achymotrypsin-like elastase family, member 2A0.033
Rup2urinary protein 20.032
Acrv1acrosomal vesicle protein 10.032
Oprk1opioid receptor, kappa 10.031
Lad1ladinin 10.031
Prodh2proline dehydrogenase (oxidase) 20.031
Tgfbr3transforming growth factor, beta receptor III0.030
LOC690418similar to Acidic proline-rich protein PRP25 precursor0.029
Atp2b4ATPase, Ca++ transporting, plasma membrane 40.029
Pon1paraoxonase 10.028
Pla2g2cphospholipase A2, group IIC0.028
Slc6a7solute carrier family 6 (neurotransmitter transporter, L-proline), member 70.027
Kcnh3potassium voltage-gated channel, subfamily H (eag-related), member 30.027
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.027
Mamdc4MAM domain containing 40.026
Arandrogen receptor0.026
Htr5a5-hydroxytryptamine (serotonin) receptor 5A0.026
Nkx6-1NK6 homeobox 10.026
Psg19pregnancy specific glycoprotein 190.026
RGD1564865similar to 20-alpha-hydroxysteroid dehydrogenase0.025
C3ar1complement component 3a receptor 10.025
Cx3cr1chemokine (C-X3-C motif) receptor 10.025
Slc30a2solute carrier family 30 (zinc transporter), member 20.025
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.025
Spp2secreted phosphoprotein 20.024
Adora2aadenosine A2a receptor0.024
Hrh2histamine receptor H 20.024
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.024
Leprleptin receptor0.024
Smr3asubmaxillary gland androgen regulated protein 3A0.024
Agxt2alanine-glyoxylate aminotransferase 20.023
RGD1310262hypothetical LOC3046500.023
Chrna4cholinergic receptor, nicotinic, alpha 40.023
Atp7bATPase, Cu++ transporting, beta polypeptide0.023
Apoa4apolipoprotein A-IV0.023
Bcl2l10BCL2-like 10 (apoptosis facilitator)0.023
Hsd3b5hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 50.023
DaoD-amino-acid oxidase0.023
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.022
Kif6kinesin family member 60.022
Chrm2cholinergic receptor, muscarinic 20.022
B3gat1beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)0.022
Syt7synaptotagmin VII0.022
Cacna1ecalcium channel, voltage-dependent, R type, alpha 1E subunit0.022
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Nmdar1NMDA receptor 10.312
Ent2Equilibrative nucleoside transporter 20.270
AdoRAdenosine receptor0.142
GluRIIAGlutamate receptor IIA0.056
fd85Eforkhead domain 85E0.049
DopRDopamine receptor0.049
CG17278CG17278 gene product from transcript CG17278-RA0.045
CG3164CG3164 gene product from transcript CG3164-RA0.033
CG11961CG11961 gene product from transcript CG11961-RB0.029
l(2)05510lethal (2) 055100.028
CG6724CG6724 gene product from transcript CG6724-RA0.025
l(3)mbnlethal (3) malignant blood neoplasm0.025
CG42640CG42640 gene product from transcript CG42640-RA0.024
Atg6Autophagy-specific gene 60.022
CG42629CG42629 gene product from transcript CG42629-RB0.021
HDAC6CG6170 gene product from transcript CG6170-RA0.021
StamSignal transducing adaptor molecule0.018
CG10992CG10992 gene product from transcript CG10992-RA0.018
dpr5CG5308 gene product from transcript CG5308-RA0.017
ZnT35CCG3994 gene product from transcript CG3994-RA0.016
Spt-ISerine palmitoyltransferase subunit I0.016
CG12214CG12214 gene product from transcript CG12214-RB0.016
CG32711CG32711 gene product from transcript CG32711-RA0.015
KaiRIACG18039 gene product from transcript CG18039-RA0.014
CG32795CG32795 gene product from transcript CG32795-RA0.014
l(2)03659lethal (2) 036590.013
CG7860CG7860 gene product from transcript CG7860-RA0.013
GldGlucose dehydrogenase0.013
CrebB-17ACyclic-AMP response element binding protein B at 17A0.012
CG42542CG42542 gene product from transcript CG42542-RE0.012
CG11317CG11317 gene product from transcript CG11317-RA0.012
Muc91CMucin 91C0.010
NFATNFAT homolog0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
MED15mediator complex subunit 150.983
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.950
ZNF263zinc finger protein 2630.778
TRIM17tripartite motif containing 170.641
UBE2D4ubiquitin-conjugating enzyme E2D 4 (putative)0.605
TRIM39tripartite motif containing 390.581
SP100SP100 nuclear antigen0.502
TRIM43tripartite motif containing 430.322
IRF1interferon regulatory factor 10.314
TRIM26tripartite motif containing 260.308
TUBGCP4tubulin, gamma complex associated protein 40.303
IFI16interferon, gamma-inducible protein 160.301
TRIM52tripartite motif containing 520.274
TRIM5tripartite motif containing 50.233
RBCK1RanBP-type and C3HC4-type zinc finger containing 10.158
MCOLN1mucolipin 10.154
UBE2Uubiquitin-conjugating enzyme E2U (putative)0.148
EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 20.130
IRF2interferon regulatory factor 20.114
NMIN-myc (and STAT) interactor0.113
SP110SP110 nuclear body protein0.112
IRF9interferon regulatory factor 90.102
TRIM35tripartite motif containing 350.100
UBE2Zubiquitin-conjugating enzyme E2Z0.098
TRIM22tripartite motif containing 220.086
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.085
PMLpromyelocytic leukemia0.085
TRIM8tripartite motif containing 80.083
RNF130ring finger protein 1300.082
MR1major histocompatibility complex, class I-related0.080
SREBF1sterol regulatory element binding transcription factor 10.078
TRIM6-TRIM34TRIM6-TRIM34 readthrough0.066
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.063
IFI44interferon-induced protein 440.060
MLLT6myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 60.057
C19orf66chromosome 19 open reading frame 660.053
PRKCAprotein kinase C, alpha0.051
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.049
DTX3Ldeltex 3-like (Drosophila)0.047
PLSCR1phospholipid scramblase 10.042
STAT2signal transducer and activator of transcription 2, 113kDa0.042
TRIM6tripartite motif containing 60.040
PHF11PHD finger protein 110.040
PIK3C2Bphosphoinositide-3-kinase, class 2, beta polypeptide0.040
RNF5ring finger protein 50.037
TRANK1tetratricopeptide repeat and ankyrin repeat containing 10.037
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.037
CTSOcathepsin O0.034
SDSLserine dehydratase-like0.034
ZBTB8Azinc finger and BTB domain containing 8A0.033
MKRN3makorin ring finger protein 30.032
TRIM25tripartite motif containing 250.031
DAXXdeath-domain associated protein0.030
MUL1mitochondrial E3 ubiquitin protein ligase 10.026
BFARbifunctional apoptosis regulator0.025
RNF114ring finger protein 1140.025
TRIM34tripartite motif containing 340.025
BTN3A2butyrophilin, subfamily 3, member A20.025
GIMAP2GTPase, IMAP family member 20.024
DDX60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.023
RNF166ring finger protein 1660.023
PLCD4phospholipase C, delta 40.023
MAGEF1melanoma antigen family F, 10.022
SAMD9sterile alpha motif domain containing 90.022
BTN3A3butyrophilin, subfamily 3, member A30.022
UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)0.022
TRIM21tripartite motif containing 210.022
MAGEA1melanoma antigen family A, 1 (directs expression of antigen MZ2-E)0.022
FADDFas (TNFRSF6)-associated via death domain0.021
USP4ubiquitin specific peptidase 4 (proto-oncogene)0.021
REREarginine-glutamic acid dipeptide (RE) repeats0.021
MEX3Bmex-3 homolog B (C. elegans)0.020
RNF25ring finger protein 250.019
MYD88myeloid differentiation primary response gene (88)0.019
SPG21spastic paraplegia 21 (autosomal recessive, Mast syndrome)0.019
TDRD7tudor domain containing 70.017
ETS1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.017
MKRN1makorin ring finger protein 10.017
IL15RAinterleukin 15 receptor, alpha0.016
SPTBspectrin, beta, erythrocytic0.016
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.016
TRIM31tripartite motif containing 310.015
BTN2A1butyrophilin, subfamily 2, member A10.015
PIAS3protein inhibitor of activated STAT, 30.014
FHL3four and a half LIM domains 30.014
RASSF1Ras association (RalGDS/AF-6) domain family member 10.014
GYPEglycophorin E (MNS blood group)0.014
RLIMring finger protein, LIM domain interacting0.013
CHFRcheckpoint with forkhead and ring finger domains0.013
LY75lymphocyte antigen 750.013
UBTD1ubiquitin domain containing 10.013
ZNF221zinc finger protein 2210.012
HIPK2homeodomain interacting protein kinase 20.012
RHDRh blood group, D antigen0.012
SLFN12schlafen family member 120.012
MX2myxovirus (influenza virus) resistance 2 (mouse)0.011
LIPAlipase A, lysosomal acid, cholesterol esterase0.011
CASP4caspase 4, apoptosis-related cysteine peptidase0.011
NFYCnuclear transcription factor Y, gamma0.011
RNASELribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism