The network for 'ventricular cardiac muscle cell development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ventricular cardiac muscle cell development

The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.

NameDescriptionProbabilityFunc Analog Organism
Pttg1pituitary tumor-transforming 10.359
Top2atopoisomerase (DNA) II alpha0.334
Ube2cubiquitin-conjugating enzyme E2C0.331
Cdk1cyclin-dependent kinase 10.274
Ccnb1cyclin B10.179
Spc25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.173
LOC689399hypothetical protein LOC6893990.153
Cdca3cell division cycle associated 30.148
Cdkn3cyclin-dependent kinase inhibitor 30.134
Traf4af1TRAF4 associated factor 10.129
Rrm2ribonucleotide reductase M20.063
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.056
Ccna2cyclin A20.046
Kifc1kinesin family member C10.040
Stmn1stathmin 10.038
Mcm6minichromosome maintenance complex component 60.036
Kif2ckinesin family member 2C0.034
Racgap1Rac GTPase-activating protein 10.032
Ckmcreatine kinase, muscle0.027
Pgam2phosphoglycerate mutase 2 (muscle)0.025
Hmmrhyaluronan mediated motility receptor (RHAMM)0.024
Cks2CDC28 protein kinase regulatory subunit 20.022
Nrapnebulin-related anchoring protein0.019
Nusap1nucleolar and spindle associated protein 10.019
Ns5atp9NS5A (hepatitis C virus) transactivated protein 90.018
Mki67antigen identified by monoclonal antibody Ki-670.017
Rrbp1ribosome binding protein 10.016
Rpa2replication protein A20.015
Tubb5tubulin, beta 50.014
Sdc1syndecan 10.014
Actn1actinin, alpha 10.013
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.012
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.012
Kif22kinesin family member 220.011
Ccne1cyclin E10.011
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.010
Depdc1DEP domain containing 10.010
Mcm5minichromosome maintenance complex component 50.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
bmp4bone morphogenetic protein 40.760
nkx2.5NK2 transcription factor related 50.506
vmhcventricular myosin heavy chain0.386
desmadesmin a0.373
actc1aactin, alpha, cardiac muscle 1a0.311
atp2a2aATPase, Ca++ transporting, cardiac muscle, slow twitch 2a0.296
ikzf1IKAROS family zinc finger 1 (Ikaros)0.240
myl7myosin, light polypeptide 7, regulatory0.237
tnnc1btroponin C type 1b (slow)0.232
cmlc1cardiac myosin light chain-10.196
tnnc2troponin C type 2 (fast)0.191
tbx20T-box 200.185
ttnatitin a0.185
rbfox1lRNA binding protein, fox-1 homolog (C. elegans) 1-like0.180
bmp2abone morphogenetic protein 2a0.129
atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.105
ckmbcreatine kinase, muscle b0.094
nanos3nanos homolog 30.093
pvalb4parvalbumin 40.091
tbx1T-box 10.087
myod1myogenic differentiation 10.081
dlx4adistal-less homeobox gene 4a0.074
evx1even-skipped homeobox 10.070
zgc:66286zgc:662860.059
lama4laminin, alpha 40.057
fgf10afibroblast growth factor 10a0.049
dlx5adistal-less homeobox gene 5a0.048
bmp2bbone morphogenetic protein 2b0.047
actc1bactin, alpha, cardiac muscle 1b0.044
tmem38atransmembrane protein 38A0.041
slc8a1asolute carrier family 8 (sodium/calcium exchanger), member 1a0.040
sema3aasemaphorin 3aa0.040
msxdmuscle segment homeobox D0.039
vegfcvascular endothelial growth factor c0.035
casq2calsequestrin 20.030
cx43connexin 430.030
znfl2azinc finger-like gene 2a0.026
aldoabaldolase a, fructose-bisphosphate, b0.025
ldb3bLIM domain binding 3b0.025
bmp10bone morphogenetic protein 100.024
flt4fms-related tyrosine kinase 40.024
pvalb2parvalbumin 20.023
myl1myosin, light chain 1, alkali; skeletal, fast0.020
tnni2a.4troponin I, skeletal, fast 2a.40.020
wu:fb01h12wu:fb01h120.020
myl10myosin, light chain 10, regulatory0.020
hspb12heat shock protein, alpha-crystallin-related, b120.020
nav3neuron navigator 30.019
hoxb5bhomeo box B5b0.018
brd2abromodomain-containing 2a0.018
gsnagelsolin a0.016
actn3bactinin alpha 3b0.015
ttnbtitin b0.015
zgc:165344zgc:1653440.015
dlx6adistal-less homeobox gene 6a0.015
nrp1aneuropilin 1a0.014
wu:fc31e07wu:fc31e070.014
fgf24fibroblast growth factor 240.014
psat1phosphoserine aminotransferase 10.014
lamc3laminin, gamma 30.014
tnni1btroponin I, skeletal, slow b0.014
bhmtbetaine-homocysteine methyltransferase0.013
lrrc10leucine rich repeat containing 100.013
tnnt3btroponin T3b, skeletal, fast0.013
cx30.3connexin 30.30.013
tgfbr2transforming growth factor, beta receptor II0.012
pabpc4poly(A) binding protein, cytoplasmic 4 (inducible form)0.012
cav3caveolin 30.012
rbm24bRNA binding motif protein 24b0.011
fhl2bfour and a half LIM domains 2b0.011
me2malic enzyme 2, NAD(+)-dependent, mitochondrial0.011
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.011
pacsin3protein kinase C and casein kinase substrate in neurons 30.011
macf1microtubule-actin crosslinking factor 10.010
csrp3cysteine and glycine-rich protein 3 (cardiac LIM protein)0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Hand2heart and neural crest derivatives expressed transcript 20.999
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.997
Hand1heart and neural crest derivatives expressed transcript 10.997
Shhsonic hedgehog0.995
Gata4GATA binding protein 40.989
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.949
Fgfr2fibroblast growth factor receptor 20.938
Fgf8fibroblast growth factor 80.935
Sox9SRY-box containing gene 90.915
Foxc1forkhead box C10.891
Fgfr3fibroblast growth factor receptor 30.787
Pitx2paired-like homeodomain transcription factor 20.754
Bmp4bone morphogenetic protein 40.665
Tgfb2transforming growth factor, beta 20.650
Foxc2forkhead box C20.622
Ror2receptor tyrosine kinase-like orphan receptor 20.620
Msx1homeobox, msh-like 10.500
Bmp7bone morphogenetic protein 70.486
Isl1ISL1 transcription factor, LIM/homeodomain0.415
Tbx3T-box 30.404
Tcfap2atranscription factor AP-2, alpha0.390
Gli2GLI-Kruppel family member GLI20.356
Pitx1paired-like homeodomain transcription factor 10.304
Cdk1cyclin-dependent kinase 10.300
Ptpn11protein tyrosine phosphatase, non-receptor type 110.256
Tbx5T-box 50.244
Hey2hairy/enhancer-of-split related with YRPW motif 20.237
Gata6GATA binding protein 60.205
Gli3GLI-Kruppel family member GLI30.181
Gja1gap junction protein, alpha 10.172
Zfpm2zinc finger protein, multitype 20.169
Tbx1T-box 10.159
Rspo2R-spondin 2 homolog (Xenopus laevis)0.156
Prrx1paired related homeobox 10.141
Runx2runt related transcription factor 20.138
Nkx6-1NK6 homeobox 10.136
Pthlhparathyroid hormone-like peptide0.132
Gscgoosecoid homeobox0.129
Msx2homeobox, msh-like 20.126
Efnb2ephrin B20.109
Mef2cmyocyte enhancer factor 2C0.104
Hoxa13homeobox A130.103
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.100
Ccna2cyclin A20.099
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.098
Pax3paired box gene 30.092
Hoxd13homeobox D130.092
Gata5GATA binding protein 50.091
Lmnb1lamin B10.089
Mesp1mesoderm posterior 10.088
Alx4aristaless-like homeobox 40.082
Prc1protein regulator of cytokinesis 10.081
Foxe1forkhead box E10.080
Hdac4histone deacetylase 40.079
Lmx1bLIM homeobox transcription factor 1 beta0.078
Scn5asodium channel, voltage-gated, type V, alpha0.071
Ccnb1cyclin B10.067
Ntf3neurotrophin 30.064
Jag1jagged 10.062
Tbx4T-box 40.062
Nkx3-2NK3 homeobox 20.061
Gdf6growth differentiation factor 60.061
Plk1polo-like kinase 1 (Drosophila)0.060
Gdf5growth differentiation factor 50.060
Bmpr1abone morphogenetic protein receptor, type 1A0.060
Kif20akinesin family member 20A0.060
Otx2orthodenticle homolog 2 (Drosophila)0.058
Pdx1pancreatic and duodenal homeobox 10.056
Cnn1calponin 10.055
Ccnb2cyclin B20.052
Meox2mesenchyme homeobox 20.051
Nognoggin0.050
Gja3gap junction protein, alpha 30.049
Itgb1integrin beta 1 (fibronectin receptor beta)0.049
Ighmbp2immunoglobulin mu binding protein 20.048
Gja5gap junction protein, alpha 50.046
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.046
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.045
Atg12autophagy-related 12 (yeast)0.039
Rxraretinoid X receptor alpha0.038
Alx3aristaless-like homeobox 30.037
Foxh1forkhead box H10.035
Tbx15T-box 150.035
Esx1extraembryonic, spermatogenesis, homeobox 10.034
Iduaiduronidase, alpha-L-0.034
Lmnb2lamin B20.034
Birc5baculoviral IAP repeat-containing 50.033
Acvr1activin A receptor, type 10.030
Itga3integrin alpha 30.028
ND6NADH dehydrogenase subunit 60.028
Barx1BarH-like homeobox 10.028
Hdac5histone deacetylase 50.026
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.026
Vegfavascular endothelial growth factor A0.025
Pax9paired box gene 90.023
Smad6MAD homolog 6 (Drosophila)0.022
Insm1insulinoma-associated 10.022
Art5ADP-ribosyltransferase 50.021
Nos3nitric oxide synthase 3, endothelial cell0.021
Cfc1cripto, FRL-1, cryptic family 10.021
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism