The network for 'positive regulation of nucleoside metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of nucleoside metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.

NameDescriptionProbabilityFunc Analog Organism
Adora2aadenosine A2a receptor0.363
Gng7guanine nucleotide binding protein (G protein), gamma 70.354
Arpc2actin related protein 2/3 complex, subunit 20.211
Epas1endothelial PAS domain protein 10.205
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.199
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.171
Pip4k2bphosphatidylinositol-5-phosphate 4-kinase, type II, beta0.162
Sox17SRY (sex determining region Y)-box 170.162
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.150
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.142
Pja2praja 2, RING-H2 motif containing0.141
Gucy1b3guanylate cyclase 1, soluble, beta 30.124
Myo1dmyosin ID0.123
Gria1glutamate receptor, ionotropic, AMPA 10.122
Arl1ADP-ribosylation factor-like 10.119
Homer1homer homolog 1 (Drosophila)0.116
Ddr1discoidin domain receptor tyrosine kinase 10.113
Anxa1annexin A10.109
Myo1cmyosin IC0.108
Nlgn2neuroligin 20.105
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.104
Kcnab1potassium voltage-gated channel, shaker-related subfamily, beta member 10.104
Dlg3discs, large homolog 3 (Drosophila)0.098
Pik3cdphosphoinositide-3-kinase, catalytic, delta polypeptide0.095
Prkcbprotein kinase C, beta0.092
Fgf2fibroblast growth factor 20.088
Lman1lectin, mannose-binding, 10.085
Amphamphiphysin0.084
Cyth1cytohesin 10.084
Apbb1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.083
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.082
Lynx1Ly6/neurotoxin 10.081
Akap1A kinase (PRKA) anchor protein 10.081
Lphn2latrophilin 20.078
Pld2phospholipase D20.077
Slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.077
Stk39serine/threonine kinase 39, STE20/SPS1 homolog (yeast)0.076
Sel1lsel-1 suppressor of lin-12-like (C. elegans)0.075
Brafv-raf murine sarcoma viral oncogene homolog B10.074
RfngRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase0.074
Gabra4gamma-aminobutyric acid (GABA) A receptor, alpha 40.074
Prkchprotein kinase C, eta0.073
Klf6Kruppel-like factor 60.070
Chn2chimerin (chimaerin) 20.070
Prkcgprotein kinase C, gamma0.070
Cmklr1chemokine-like receptor 10.068
Ptk2bPTK2B protein tyrosine kinase 2 beta0.066
Aif1lallograft inflammatory factor 1-like0.066
Gps1G protein pathway suppressor 10.066
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.066
Taglntransgelin0.065
Gipc1GIPC PDZ domain containing family, member 10.064
Ugt8UDP glycosyltransferase 80.062
Fgfr2fibroblast growth factor receptor 20.061
Pctk2PCTAIRE protein kinase 20.061
Fgfr1Fibroblast growth factor receptor 10.061
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.061
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.061
Adaradenosine deaminase, RNA-specific0.061
Timp1TIMP metallopeptidase inhibitor 10.060
Dgkgdiacylglycerol kinase, gamma0.057
Cfpcomplement factor properdin0.057
RhdRh blood group, D antigen0.057
Vipr1vasoactive intestinal peptide receptor 10.056
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.056
Mcpt4mast cell protease 40.055
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.054
Utrnutrophin0.054
St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 30.053
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.052
Plcg1phospholipase C, gamma 10.052
Pde1bphosphodiesterase 1B, calmodulin-dependent0.051
Copb2coatomer protein complex, subunit beta 2 (beta prime)0.051
Mcammelanoma cell adhesion molecule0.051
Itpr1inositol 1,4,5-triphosphate receptor, type 10.050
Gucy1a3guanylate cyclase 1, soluble, alpha 30.050
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.049
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.049
Chrm1cholinergic receptor, muscarinic 10.049
Egr3early growth response 30.049
Unc5bunc-5 homolog B (C. elegans)0.049
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.048
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.048
Copb1coatomer protein complex, subunit beta 10.048
Plxdc1plexin domain containing 10.048
Clic4chloride intracellular channel 40.048
KitlgKIT ligand0.047
NmiN-myc (and STAT) interactor0.047
Ripk3receptor-interacting serine-threonine kinase 30.047
Eef1a2eukaryotic translation elongation factor 1 alpha 20.047
Flt1FMS-related tyrosine kinase 10.046
Pi4kaphosphatidylinositol 4-kinase, catalytic, alpha0.046
Dlg4discs, large homolog 4 (Drosophila)0.045
Rasal1RAS protein activator like 1 (GAP1 like)0.045
Mpdzmultiple PDZ domain protein0.045
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.044
Epb41l1erythrocyte membrane protein band 4.1-like 10.044
Tgfbr2transforming growth factor, beta receptor II0.044
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.044
Sirpasignal-regulatory protein alpha0.044
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
CELE_F47G4.4Protein F47G4.40.342
sup-17Protein SUP-170.262
lag-1Protein LAG-10.181
rig-6Protein RIG-60.164
atg-11Protein ATG-110.156
plc-3Protein PLC-30.139
F32B5.7Protein F32B5.70.136
rab-5Protein RAB-50.130
rme-4Protein RME-40.124
goa-1Protein GOA-10.119
mpk-1Protein MPK-10.111
flh-2Protein FLH-20.110
dpf-3Protein DPF-30.106
sad-1Protein SAD-10.097
itr-1Protein ITR-10.097
eor-2Protein EOR-20.093
spdl-1Protein SPDL-10.093
abl-1Protein ABL-10.087
T23F2.2Protein T23F2.20.084
plk-1Protein PLK-10.083
unc-71Protein UNC-710.083
rpm-1Protein RPM-10.079
egrh-1Protein EGRH-10.076
ptp-4Protein PTP-40.074
rgs-6Protein RGS-60.073
lin-45Protein LIN-450.073
eef-1A.1Protein EEF-1A.10.072
sma-9Protein SMA-90.070
egl-8Protein EGL-80.069
F35G2.1Protein F35G2.10.067
mel-28Protein MEL-280.067
sas-4Protein SAS-40.063
ash-2Protein ASH-20.063
unc-53Protein UNC-530.062
T04F8.6Protein T04F8.60.061
zfp-3Protein ZFP-30.060
afd-1Protein AFD-10.059
larp-5Protein LARP-50.058
mbk-1Protein MBK-10.057
ced-10Protein CED-100.056
zoo-1Protein ZOO-10.054
unc-26Protein UNC-260.052
coh-3Protein COH-30.052
gei-4Protein GEI-40.050
F10D7.5Protein F10D7.50.049
sur-2Protein SUR-20.049
F09A5.4Protein F09A5.40.049
cah-6Protein CAH-60.048
dpy-21Protein DPY-210.047
CELE_K08E7.6Protein K08E7.60.047
gpb-1Protein GPB-10.047
fhod-1Protein FHOD-10.047
CELE_T26A8.4Protein T26A8.40.046
rsbp-1Protein RSBP-10.046
F52G3.1Protein F52G3.10.046
T14B1.1Protein T14B1.10.045
nhr-256Protein NHR-2560.044
F28B3.1Protein F28B3.10.044
cyld-1Protein CYLD-10.043
C11H1.3Protein C11H1.30.043
tmc-2Protein TMC-20.043
pak-1Protein PAK-10.043
daf-19Protein DAF-190.043
tomm-20Protein TOMM-200.043
egl-18Protein EGL-180.042
hif-1Protein HIF-10.042
sem-5Protein SEM-50.041
tag-303Protein TAG-3030.041
crt-1Protein CRT-10.040
cnt-2Protein CNT-20.040
unc-2Protein UNC-20.040
zyg-9Protein ZYG-90.040
nhr-67Protein NHR-670.039
mpz-1Protein MPZ-10.039
exc-5Protein EXC-50.039
pkg-1Protein PKG-10.038
gei-8Protein GEI-80.037
C45B2.6Protein C45B2.60.037
magi-1Protein MAGI-10.037
rps-2Protein RPS-20.037
unc-79Protein UNC-790.036
nrx-1Protein NRX-10.035
T19A5.1Protein T19A5.10.035
sam-10Protein SAM-100.035
snf-1Protein SNF-10.034
tmd-2Protein TMD-20.034
lin-48Protein LIN-480.034
abts-1Protein ABTS-10.034
lfi-1Protein LFI-10.033
stau-1Protein STAU-10.033
ykt-6Protein YKT-60.032
frm-3Protein FRM-30.032
pqn-55Protein PQN-550.031
F22D3.2Protein F22D3.20.031
elt-6Protein ELT-60.031
perm-5Protein PERM-50.030
ttx-1Protein TTX-10.030
tbx-2Protein TBX-20.029
syd-9Protein SYD-90.029
cgef-2Protein CGEF-20.029
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
hsp90a.2heat shock protein 90-alpha 20.259
tnnc2troponin C type 2 (fast)0.259
ckmbcreatine kinase, muscle b0.197
rtcd1RNA terminal phosphate cyclase domain 10.192
tpm4tropomyosin 40.190
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.164
bcl2B-cell leukemia/lymphoma 20.161
bidaBH3 interacting domain death agonist0.157
pgam2phosphoglycerate mutase 2 (muscle)0.154
pvalb4parvalbumin 40.132
nf1aneurofibromin 1a0.122
rtn1areticulon 1a0.120
icnictacalcin0.112
ahctf1AT hook containing transcription factor 10.111
junjun proto-oncogene0.108
pvalb1parvalbumin 10.105
cnn2calponin 20.105
rrasrelated RAS viral (r-ras) oncogene homolog0.104
tpm3tropomyosin 30.104
perpPERP, TP53 apoptosis effector0.103
mcm6MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)0.101
pdlim1PDZ and LIM domain 1 (elfin)0.096
depdc1aDEP domain containing 1a0.095
tnnt3btroponin T3b, skeletal, fast0.094
ephb4beph receptor B4b0.093
tipintimeless interacting protein0.092
zgc:77517zgc:775170.089
zgc:153997zgc:1539970.089
mylz2myosin, light polypeptide 2, skeletal muscle0.089
ube2d1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.087
rrp12ribosomal RNA processing 12 homolog (S. cerevisiae)0.087
dedd1death effector domain-containing 10.086
hspa4aheat shock protein 4a0.086
nme2b.2non-metastatic cells 2b.2, protein (NM23B) expressed in0.085
epb41l5erythrocyte membrane protein band 4.1 like 50.085
gapdhglyceraldehyde-3-phosphate dehydrogenase0.084
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.082
atp2b1aATPase, Ca++ transporting, plasma membrane 1a0.079
pvalb2parvalbumin 20.079
mat2amethionine adenosyltransferase II, alpha0.078
msnamoesin a0.076
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.074
dnmt7DNA (cytosine-5-)-methyltransferase 70.074
socs3asuppressor of cytokine signaling 3a0.071
gnaiaguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a0.071
sox4aSRY-box containing gene 4a0.071
rcn1reticulocalbin 1, EF-hand calcium binding domain0.071
tnni2a.4troponin I, skeletal, fast 2a.40.070
copebcore promoter element binding protein0.070
vmhcventricular myosin heavy chain0.070
actc1bactin, alpha, cardiac muscle 1b0.069
ldb3bLIM domain binding 3b0.068
nf1bneurofibromin 1b0.068
cebpdCCAAT/enhancer binding protein (C/EBP), delta0.067
dnaja1lDnaJ (Hsp40) homolog, subfamily A, member 1, like0.067
cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.067
gsnagelsolin a0.066
yap1Yes-associated protein 10.065
si:ch211-232m7.1si:ch211-232m7.10.065
rps6ka3aribosomal protein S6 kinase, polypeptide 3a0.064
atp2a1lATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like0.063
plk3polo-like kinase 3 (Drosophila)0.062
s100v2S100 calcium binding protein V20.061
ccng1cyclin G10.061
mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.061
gna12guanine nucleotide binding protein (G protein) alpha 120.061
slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.061
mcl1bmyeloid cell leukemia sequence 1b0.061
tagln2transgelin 20.060
ahnakAHNAK nucleoprotein0.060
zgc:56466zgc:564660.060
anxa2aannexin A2a0.059
sncgbsynuclein, gamma b (breast cancer-specific protein 1)0.059
hbegfaheparin-binding EGF-like growth factor a0.059
unc5bunc-5 homolog B (C. elegans)0.058
lifrbleukemia inhibitory factor receptor alpha b0.058
ehd2EH-domain containing 20.057
nebnebulin0.057
zgc:91870zgc:918700.055
ilkintegrin linked kinase0.055
ccnb2cyclin B20.055
atf3activating transcription factor 30.055
ptgs2aprostaglandin-endoperoxide synthase 2a0.054
kif20bbkinesin family member 20Bb0.054
pif1PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)0.054
si:dkeyp-117h8.4si:dkeyp-117h8.40.053
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.053
cxcr3.2chemokine (C-X-C motif) receptor 3.20.053
chac1ChaC, cation transport regulator-like 10.053
pak2ap21 (CDKN1A)-activated kinase 2a0.052
junbjun B proto-oncogene0.052
socs3bsuppressor of cytokine signaling 3b0.052
sox21aSRY-box containing gene 21a0.051
fem1cfem-1 homolog c (C.elegans)0.051
mrpl38mitochondrial ribosomal protein L380.050
sec24cSEC24 family, member C (S. cerevisiae)0.050
gstalglutathione S-transferase, alpha-like0.049
scinlbscinderin like b0.049
iqgap1IQ motif containing GTPase activating protein 10.048
pvalb3parvalbumin 30.048
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
cnocanoe0.576
WnkCG7177 gene product from transcript CG7177-RA0.558
RhoGAP68FCG6811 gene product from transcript CG6811-RA0.514
AbiAbelson interacting protein0.493
Prp31CG6876 gene product from transcript CG6876-RA0.488
stgstring0.459
plexBplexin B0.458
RhebCG1081 gene product from transcript CG1081-RA0.443
RhoGAP93BCG3421 gene product from transcript CG3421-RA0.430
cenG1Acentaurin gamma 1A0.426
NaCP60ENa channel protein 60E0.414
trioCG18214 gene product from transcript CG18214-RA0.386
simasimilar0.328
pucpuckered0.284
Pk61CProtein kinase 61C0.276
Dap160Dynamin associated protein 1600.266
PTP-ERProtein tyrosine phosphatase-ERK/Enhancer of Ras10.251
HemHEM-protein0.244
Pi3K92ECG4141 gene product from transcript CG4141-RB0.241
l(2)k16918lethal (2) k169180.234
PknProtein kinase related to protein kinase N0.225
CycACyclin A0.221
ApcAPC-like0.218
dosdaughter of sevenless0.207
ptcpatched0.204
pod1CG4532 gene product from transcript CG4532-RF0.191
CG7158CG7158 gene product from transcript CG7158-RA0.185
mbcmyoblast city0.181
rapsrapsynoid0.180
rapretina aberrant in pattern0.180
Smg1CG32743 gene product from transcript CG32743-RA0.174
synjsynaptojanin0.167
rokRho-kinase0.166
sglsugarless0.164
staistathmin0.160
mysmyospheroid0.152
tsrtwinstar0.152
PtenCG5671 gene product from transcript CG5671-RB0.150
G-ialpha65AG protein alphai subunit 65A0.149
SosSon of sevenless0.145
SbfSET domain binding factor0.144
kuzkuzbanian0.138
smosmoothened0.137
nwknervous wreck0.134
giggigas0.133
taytay bridge0.131
Drl-2Derailed 20.131
CG4552CG4552 gene product from transcript CG4552-RA0.129
chercheerio0.127
Vps45Vacuolar protein sorting 450.127
FsFollistatin0.122
neurneuralized0.122
CG11033CG11033 gene product from transcript CG11033-RB0.122
Rbsn-5Rabenosyn-50.119
HiraCG12153 gene product from transcript CG12153-RA0.119
ShcSHC-adaptor protein0.118
SNF1ASNF1A/AMP-activated protein kinase0.117
sizschizo0.116
Ced-12CG5336 gene product from transcript CG5336-RA0.112
CG6509CG6509 gene product from transcript CG6509-RB0.110
ttktramtrack0.109
CG3573CG3573 gene product from transcript CG3573-RA0.107
Mlc2Myosin light chain 20.107
frcfringe connection0.106
Su(Tpl)CG32217 gene product from transcript CG32217-RB0.104
CG9426CG9426 gene product from transcript CG9426-RA0.104
PliPellino0.103
EphrinCG1862 gene product from transcript CG1862-RA0.100
mbtmushroom bodies tiny0.100
carcarnation0.098
CG8334CG8334 gene product from transcript CG8334-RA0.098
jumujumeau0.094
GugGrunge0.090
CG8155CG8155 gene product from transcript CG8155-RA0.088
AlkCG8250 gene product from transcript CG8250-RA0.087
yataCG1973 gene product from transcript CG1973-RA0.086
prodproliferation disrupter0.085
myoglianinCG1838 gene product from transcript CG1838-RD0.084
Sin3ACG8815 gene product from transcript CG8815-RC0.083
LanALaminin A0.083
Mkp3Mitogen-activated protein kinase phosphatase 30.082
sec6CG5341 gene product from transcript CG5341-RA0.081
Fas1Fasciclin 10.078
KlcKinesin light chain0.078
MtlMig-2-like0.078
Mlp84BMuscle LIM protein at 84B0.078
linlines0.077
wupAwings up A0.076
tmodtropomodulin0.076
slssallimus0.076
rdgAretinal degeneration A0.073
sec10CG6159 gene product from transcript CG6159-RA0.072
CalpBCalpain-B0.071
Myo31DFMyosin 31DF0.071
GrafCG8948 gene product from transcript CG8948-RB0.068
Fak56DFocal Adhesion Kinase0.068
pgant3polypeptide GalNAc transferase 30.068
Tre1trapped in endoderm-10.067
inscinscuteable0.067
NNotch0.067
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.999
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.989
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.985
EGFRepidermal growth factor receptor0.978
PLCG1phospholipase C, gamma 10.961
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.953
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.947
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.942
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.933
FGFR2fibroblast growth factor receptor 20.919
PTK2PTK2 protein tyrosine kinase 20.917
SFNstratifin0.904
MDM2Mdm2 p53 binding protein homolog (mouse)0.890
BCAR1breast cancer anti-estrogen resistance 10.890
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.882
S100A11S100 calcium binding protein A110.881
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.874
NCF2neutrophil cytosolic factor 20.856
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.830
GRB2growth factor receptor-bound protein 20.821
S100A6S100 calcium binding protein A60.808
GRB7growth factor receptor-bound protein 70.781
RHOAras homolog gene family, member A0.780
ABI1abl-interactor 10.775
DNM1dynamin 10.753
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.734
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.721
SH3BP2SH3-domain binding protein 20.719
S100A8S100 calcium binding protein A80.697
SH3KBP1SH3-domain kinase binding protein 10.692
FGFR1fibroblast growth factor receptor 10.691
ERBB2IPerbb2 interacting protein0.688
S100BS100 calcium binding protein B0.685
SH3RF1SH3 domain containing ring finger 10.670
LAMTOR1late endosomal/lysosomal adaptor, MAPK and MTOR activator 10.658
ARRB1arrestin, beta 10.656
RIN3Ras and Rab interactor 30.653
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.647
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.647
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.620
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.619
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.612
FMNL1formin-like 10.612
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.606
CYTH4cytohesin 40.598
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.571
STAT5Asignal transducer and activator of transcription 5A0.552
TSC2tuberous sclerosis 20.548
STIP1stress-induced-phosphoprotein 10.543
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.532
LAMTOR2late endosomal/lysosomal adaptor, MAPK and MTOR activator 20.532
S100A9S100 calcium binding protein A90.529
ILKintegrin-linked kinase0.520
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.515
ADRBK1adrenergic, beta, receptor kinase 10.511
RACGAP1Rac GTPase activating protein 10.504
LATlinker for activation of T cells0.495
FGF1fibroblast growth factor 1 (acidic)0.494
NCKAP1NCK-associated protein 10.479
IGF1Rinsulin-like growth factor 1 receptor0.478
DOCK1dedicator of cytokinesis 10.465
FKBP4FK506 binding protein 4, 59kDa0.463
PSEN1presenilin 10.461
BCL2L1BCL2-like 10.457
SNX9sorting nexin 90.454
NCF1neutrophil cytosolic factor 10.446
BAIAP2BAI1-associated protein 20.439
RAB5ARAB5A, member RAS oncogene family0.438
HRASv-Ha-ras Harvey rat sarcoma viral oncogene homolog0.433
S100A1S100 calcium binding protein A10.430
EXOSC10exosome component 100.430
NCK2NCK adaptor protein 20.428
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.425
NCK1NCK adaptor protein 10.424
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.419
CCR5chemokine (C-C motif) receptor 50.416
HAP1huntingtin-associated protein 10.415
RASA1RAS p21 protein activator (GTPase activating protein) 10.413
OCRLoculocerebrorenal syndrome of Lowe0.402
BCL2B-cell CLL/lymphoma 20.398
PDE4DIPphosphodiesterase 4D interacting protein0.397
EMP3epithelial membrane protein 30.390
PLXND1plexin D10.389
TMSB10thymosin beta 100.389
RFWD2ring finger and WD repeat domain 20.389
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.388
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.386
ATP7AATPase, Cu++ transporting, alpha polypeptide0.384
TRAF5TNF receptor-associated factor 50.372
CNKSR2connector enhancer of kinase suppressor of Ras 20.371
BCRbreakpoint cluster region0.370
MAP4K5mitogen-activated protein kinase kinase kinase kinase 50.369
TSC1tuberous sclerosis 10.369
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.367
MPDZmultiple PDZ domain protein0.366
ITSN1intersectin 1 (SH3 domain protein)0.366
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.364
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.361
RPLP1ribosomal protein, large, P10.360
FASLGFas ligand (TNF superfamily, member 6)0.346
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Leprleptin receptor0.923
Arrb2arrestin, beta 20.921
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.914
Nf1neurofibromatosis 10.883
BrafBraf transforming gene0.840
Bcl2B-cell leukemia/lymphoma 20.831
Ctnnb1catenin (cadherin associated protein), beta 10.823
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.818
Itsn1intersectin 1 (SH3 domain protein 1A)0.790
BaxBCL2-associated X protein0.737
Ilkintegrin linked kinase0.736
Hmha1histocompatibility (minor) HA-10.719
Ptk2bPTK2 protein tyrosine kinase 2 beta0.712
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.676
Klklotho0.584
Rac1RAS-related C3 botulinum substrate 10.580
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.561
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.560
Prkccprotein kinase C, gamma0.551
Vav1vav 1 oncogene0.548
Ccl2chemokine (C-C motif) ligand 20.547
Pxnpaxillin0.538
Grb2growth factor receptor bound protein 20.510
Rasgrp2RAS, guanyl releasing protein 20.510
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.503
Tsc1tuberous sclerosis 10.501
Sox10SRY-box containing gene 100.480
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.475
Chrm1cholinergic receptor, muscarinic 1, CNS0.475
Ehmt2euchromatic histone lysine N-methyltransferase 20.475
Arrb1arrestin, beta 10.455
Selplgselectin, platelet (p-selectin) ligand0.445
Vav3vav 3 oncogene0.442
Apcadenomatosis polyposis coli0.421
Nr3c1nuclear receptor subfamily 3, group C, member 10.415
Asap1ArfGAP with SH# domain, ankyrin repeat and PH domain10.409
Pde1bphosphodiesterase 1B, Ca2+-calmodulin dependent0.402
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.387
Prkcdprotein kinase C, delta0.368
Mkl1MKL (megakaryoblastic leukemia)/myocardin-like 10.364
Dlg4discs, large homolog 4 (Drosophila)0.360
Ppargperoxisome proliferator activated receptor gamma0.341
Pip4k2aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha0.340
Vdrvitamin D receptor0.325
Ciccapicua homolog (Drosophila)0.320
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.316
Nf2neurofibromatosis 20.316
Efna1ephrin A10.312
Hdac7histone deacetylase 70.306
Pnpla2patatin-like phospholipase domain containing 20.300
Dnm1dynamin 10.299
Drd2dopamine receptor D20.280
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.280
Cd37CD37 antigen0.273
Atxn7l3ataxin 7-like 30.267
Stag2stromal antigen 20.262
Nrbp2nuclear receptor binding protein 20.255
Ptpn11protein tyrosine phosphatase, non-receptor type 110.250
Actbactin, beta0.249
Sh3bp1SH3-domain binding protein 10.248
Tmem131transmembrane protein 1310.244
Laptm5lysosomal-associated protein transmembrane 50.235
Git1G protein-coupled receptor kinase-interactor 10.229
Stxbp3asyntaxin binding protein 3A0.225
Ntf3neurotrophin 30.225
Irf5interferon regulatory factor 50.224
Wnt1wingless-related MMTV integration site 10.223
Wipf1WAS/WASL interacting protein family, member 10.222
Srgap2SLIT-ROBO Rho GTPase activating protein 20.221
Epb4.1l2erythrocyte protein band 4.1-like 20.220
Wnt7awingless-related MMTV integration site 7A0.219
Ccl12chemokine (C-C motif) ligand 120.216
Epha4Eph receptor A40.215
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.214
Phlpp1PH domain and leucine rich repeat protein phosphatase 10.213
Fgf23fibroblast growth factor 230.211
Adrbk1adrenergic receptor kinase, beta 10.208
Sema6dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.207
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.207
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.204
Pard3par-3 (partitioning defective 3) homolog (C. elegans)0.198
Mtap2microtubule-associated protein 20.193
Hif1ahypoxia inducible factor 1, alpha subunit0.192
Bcrbreakpoint cluster region0.191
Ppp1r9bprotein phosphatase 1, regulatory subunit 9B0.190
Adam11a disintegrin and metallopeptidase domain 110.186
Bcl3B-cell leukemia/lymphoma 30.185
Abractive BCR-related gene0.185
Pmaip1phorbol-12-myristate-13-acetate-induced protein 10.183
Apbb1ipamyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein0.176
Vaspvasodilator-stimulated phosphoprotein0.175
Trp53transformation related protein 530.175
Prkd2protein kinase D20.172
Kitlkit ligand0.169
Stk10serine/threonine kinase 100.167
Gja5gap junction protein, alpha 50.167
Rasgrp1RAS guanyl releasing protein 10.166
Mobpmyelin-associated oligodendrocytic basic protein0.166
Vav2vav 2 oncogene0.165
Gpr27G protein-coupled receptor 270.165
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
MKK1Mkk1p0.270
GYL1Gyl1p0.256
RHO1Rho1p0.176
SPA2Spa2p0.127
VPS15Vps15p0.114
STE11Ste11p0.104
STE5Ste5p0.095
GDI1Gdi1p0.093
SSA4Ssa4p0.082
ROM2Rom2p0.079
CDC24Cdc24p0.077
MSG5Msg5p0.077
GCD6Gcd6p0.076
SUI3Sui3p0.064
GCD7Gcd7p0.061
RGA2Rga2p0.060
VPS41Vps41p0.058
FKH1Fkh1p0.057
PKC1Pkc1p0.057
YPT53Ypt53p0.055
SEC16Sec16p0.054
CUR1Cur1p0.051
FMS1Fms1p0.050
KEL1Kel1p0.048
SUI2Sui2p0.044
CDC12Cdc12p0.044
PEA2Pea2p0.042
YIL055Chypothetical protein0.041
INP53Inp53p0.041
ATG14Atg14p0.040
GPR1Gpr1p0.040
YIP3Yip3p0.039
NDE1Nde1p0.039
GCD1Gcd1p0.037
STT4Stt4p0.037
CYK3Cyk3p0.036
FUS2Fus2p0.036
SLT2Slt2p0.036
SKT5Skt5p0.036
CHC1Chc1p0.035
ATG20Atg20p0.035
PRS2Prs2p0.035
MON1Mon1p0.035
CDC50Cdc50p0.034
STE4Ste4p0.034
AVO1Avo1p0.034
MDS3Mds3p0.033
CRZ1Crz1p0.033
MTC4Mtc4p0.033
CHS1Chs1p0.033
TOM1Tom1p0.032
FIR1Fir1p0.032
FYV8Fyv8p0.032
HOR2Hor2p0.031
SKM1Skm1p0.031
VPS38Vps38p0.031
VPS13Vps13p0.030
EXO84Exo84p0.030
PTP2Ptp2p0.029
GCD11Gcd11p0.029
FAA2Faa2p0.029
DCD1Dcd1p0.029
MBF1Mbf1p0.028
FUS1Fus1p0.028
UFO1Ufo1p0.028
NOP10Nop10p0.027
KSS1Kss1p0.027
SIA1Sia1p0.027
ARP10Arp10p0.027
HRP1Hrp1p0.026
BCK2Bck2p0.026
STI1Sti1p0.026
SWC7Swc7p0.026
GID7Gid7p0.025
VPS9Vps9p0.025
CWC23Cwc23p0.025
APM3Apm3p0.025
MOB2Mob2p0.025
BST1Bst1p0.025
URA3Ura3p0.024
LEU2Leu2p0.024
COX9Cox9p0.024
INM1Inm1p0.024
AAP1Aap1p0.024
INO2Ino2p0.024
SSK2Ssk2p0.024
YIR035Chypothetical protein0.024
ACK1Ack1p0.024
RGD1Rgd1p0.024
COX4Cox4p0.024
SPR6Spr6p0.023
BUD17Bud17p0.023
SRD1Srd1p0.023
RRI1Rri1p0.023
NEO1Neo1p0.023
BFR1Bfr1p0.023
BEM3Bem3p0.023
SSL2Ssl2p0.023
APL6Apl6p0.023
YPR148Chypothetical protein0.023