The network for 'organ regeneration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

organ regeneration

The regrowth of a lost or destroyed organ.

NameDescriptionProbabilityFunc Analog Organism
Gcgroup specific component0.587
Cav1caveolin 1, caveolae protein0.579
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.564
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.547
Gnmtglycine N-methyltransferase0.530
Pzppregnancy-zone protein0.512
Pdk4pyruvate dehydrogenase kinase, isozyme 40.468
Mug1murinoglobulin 10.462
RT1-EC2RT1 class Ib, locus EC20.404
Socs2suppressor of cytokine signaling 20.399
Fgafibrinogen alpha chain0.392
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.355
Metmet proto-oncogene0.352
Azgp1alpha-2-glycoprotein 1, zinc-binding0.347
Serpina1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10.342
Gpr116G protein-coupled receptor 1160.341
Adam7ADAM metallopeptidase domain 70.335
Fgfr2fibroblast growth factor receptor 20.316
Cxcl10chemokine (C-X-C motif) ligand 100.314
Nr4a3nuclear receptor subfamily 4, group A, member 30.306
Twist2twist homolog 2 (Drosophila)0.297
Smad7SMAD family member 70.287
Dnase1l3deoxyribonuclease 1-like 30.283
Ppp1r3bprotein phosphatase 1, regulatory (inhibitor) subunit 3B0.278
Cpb2carboxypeptidase B2 (plasma)0.269
Aldobaldolase B, fructose-bisphosphate0.262
LOC100361547Cytochrome P450, family 2, subfamily c, polypeptide 7-like0.255
Fabp1fatty acid binding protein 1, liver0.248
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.237
Ambpalpha-1-microglobulin/bikunin precursor0.236
Akr1c14aldo-keto reductase family 1, member C140.233
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.227
Mgst1microsomal glutathione S-transferase 10.226
Rararetinoic acid receptor, alpha0.226
Prlrprolactin receptor0.225
TekTEK tyrosine kinase, endothelial0.215
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.213
Gabrpgamma-aminobutyric acid (GABA-A) receptor, pi0.211
Apoa5apolipoprotein A-V0.209
Lmnalamin A0.206
Apohapolipoprotein H (beta-2-glycoprotein I)0.206
Ucp3uncoupling protein 3 (mitochondrial, proton carrier)0.204
Efnb1ephrin B10.204
Mcpt3mast cell peptidase 30.203
Cd4Cd4 molecule0.199
Cd14CD14 molecule0.196
Agtr1aangiotensin II receptor, type 1a0.193
Kdrkinase insert domain receptor0.190
Serpind1serpin peptidase inhibitor, clade D (heparin cofactor), member 10.190
Itih4inter alpha-trypsin inhibitor, heavy chain 40.183
Icam1intercellular adhesion molecule 10.182
Ces1ccarboxylesterase 1C0.180
Apoa2apolipoprotein A-II0.179
Anpepalanyl (membrane) aminopeptidase0.178
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.177
Prrx1paired related homeobox 10.175
LOC100364500RT1 class I, locus CE11-like0.173
RGD1564865similar to 20-alpha-hydroxysteroid dehydrogenase0.173
Gucy2dguanylate cyclase 2d0.170
Cd9CD9 molecule0.168
Rup2urinary protein 20.168
Cd68Cd68 molecule0.165
Plauplasminogen activator, urokinase0.165
Mef2dmyocyte enhancer factor 2D0.164
Apcsamyloid P component, serum0.161
Cps1carbamoyl-phosphate synthetase 10.161
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.154
Gucy2fguanylate cyclase 2F0.151
Bcl2B-cell CLL/lymphoma 20.148
LOC100362824caveolin 2-like0.146
C1qccomplement component 1, q subcomponent, C chain0.145
Il5interleukin 50.145
Capn2calpain 20.144
Anxa4annexin A40.143
Agxt2alanine-glyoxylate aminotransferase 20.140
LOC293989cytochrome P450-like0.135
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.133
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.133
Mgat5mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase0.131
Slco2a1solute carrier organic anion transporter family, member 2a10.131
Gbp2guanylate binding protein 20.131
Mgst2microsomal glutathione S-transferase 20.131
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.130
Muskmuscle, skeletal, receptor tyrosine kinase0.127
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.126
Ptch1patched homolog 1 (Drosophila)0.126
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.125
Hspb2heat shock protein beta 20.123
Olr1530olfactory receptor 15300.123
Ngfnerve growth factor (beta polypeptide)0.122
CartptCART prepropeptide0.120
Serpinb9serpin peptidase inhibitor, clade B (ovalbumin), member 90.118
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
cmybtranscription factor cmyb0.351
notch3notch homolog 30.158
chaf1bchromatin assembly factor 1, subunit B0.074
crb2acrumbs homolog 2a0.063
jag1ajagged 1a0.063
junbjun B proto-oncogene0.049
egr1early growth response 10.046
atf3activating transcription factor 30.046
atoh7atonal homolog 70.045
terttelomerase reverse transcriptase0.043
socs3asuppressor of cytokine signaling 3a0.042
copebcore promoter element binding protein0.040
flt4fms-related tyrosine kinase 40.039
gapdhsglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.039
pcnaproliferating cell nuclear antigen0.037
fli1afriend leukemia integration 1a0.036
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.036
stat3signal transduction and activation of transcription 30.035
slit3slit (Drosophila) homolog 30.033
mibmind bomb0.031
il6stinterleukin 6 signal transducer0.031
aldocbaldolase C, fructose-bisphosphate, b0.031
antxr1anthrax toxin receptor 10.030
mitfamicrophthalmia-associated transcription factor a0.029
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.029
cahzcarbonic anhydrase0.029
metmet proto-oncogene (hepatocyte growth factor receptor)0.029
hlx1H2.0-like homeo box 1 (Drosophila)0.028
duoxdual oxidase0.028
ahr2aryl hydrocarbon receptor 20.028
col4a5collagen, type IV, alpha 5 (Alport syndrome)0.027
efnb2aephrin B2a0.026
fabp11afatty acid binding protein 11a0.026
gdf6agrowth differentiation factor 6a0.026
tnfrsfatumor necrosis factor receptor superfamily, member a0.026
scube2signal peptide, CUB domain, EGF-like 20.026
uroduroporphyrinogen decarboxylase0.025
socs3bsuppressor of cytokine signaling 3b0.025
lama4laminin, alpha 40.024
plekhh1pleckstrin homology domain containing, family H (with MyTH4 domain) member 10.024
igf2binsulin-like growth factor 2b0.023
dnmt8DNA (cytosine-5-)-methyltransferase 80.023
LOC554173abnormal spindles0.023
dctn1adynactin 1a0.022
igfbp7insulin-like growth factor binding protein 70.022
prdm5PR domain containing 50.022
nfe2nuclear factor, erythroid-derived 20.021
aqp8a.1aquaporin 8a, tandem duplicate 10.021
ephb4aeph receptor B4a0.021
mybl2myeloblastosis oncogene-like 20.021
rad21RAD21 homolog (S. pombe)0.021
gas6growth arrest-specific 60.020
epas1bendothelial PAS domain protein 1b0.020
pacsin3protein kinase C and casein kinase substrate in neurons 30.020
LOC100534970hypothetical protein LOC1005349700.019
LOC555482tachykinin receptor 3-like0.019
tshz2teashirt zinc finger homeobox 20.019
fosl2fos-like antigen 20.019
prom1aprominin 1a0.019
fosv-fos FBJ murine osteosarcoma viral oncogene homolog0.019
tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.019
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.019
ctsl1acathepsin L, 1 a0.019
sat1aspermidine/spermine N1-acetyltransferase 1a0.019
lppLIM domain containing preferred translocation partner in lipoma0.018
mef2amyocyte enhancer factor 2a0.018
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.018
fgf10afibroblast growth factor 10a0.018
uchl1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.018
igfbp1ainsulin-like growth factor binding protein 1a0.018
efnb3bephrin B3b0.018
mcm6MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)0.018
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.018
celsr3cadherin, EGF LAG seven-pass G-type receptor 30.017
gtf2h4general transcription factor IIH, polypeptide 40.017
hmga1ahigh mobility group AT-hook 1a0.017
lmnalamin A0.017
chrm2acholinergic receptor, muscarinic 2a0.017
eno1enolase 1, (alpha)0.017
fabp2fatty acid binding protein 2, intestinal0.017
slc9a8solute carrier family 9 (sodium/hydrogen exchanger), member 80.017
hoxd3ahomeo box D3a0.017
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.017
igf1rainsulin-like growth factor 1a receptor0.017
mcl1bmyeloid cell leukemia sequence 1b0.017
tal1T-cell acute lymphocytic leukemia 10.017
aldh1a3aldehyde dehydrogenase 1 family, member A30.016
jak1Janus kinase 10.016
nr1i2nuclear receptor subfamily 1, group I, member 20.016
rspo1R-spondin homolog (Xenopus laevis)0.016
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Lyz2lysozyme 20.966
Cdk2cyclin-dependent kinase 20.837
Il6stinterleukin 6 signal transducer0.823
Ptpn11protein tyrosine phosphatase, non-receptor type 110.763
Cd19CD19 antigen0.516
1100001G20RikRIKEN cDNA 1100001G20 gene0.508
Cdkn1bcyclin-dependent kinase inhibitor 1B0.503
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.465
Leprleptin receptor0.464
Cdk4cyclin-dependent kinase 40.444
Agtr1aangiotensin II receptor, type 1a0.440
Egfrepidermal growth factor receptor0.430
Jak2Janus kinase 20.385
Notch2Notch gene homolog 2 (Drosophila)0.385
Trp53transformation related protein 530.378
Shc1src homology 2 domain-containing transforming protein C10.342
Gab2growth factor receptor bound protein 2-associated protein 20.316
Grb2growth factor receptor bound protein 20.300
Stat3signal transducer and activator of transcription 30.275
Ifnginterferon gamma0.263
Ppargperoxisome proliferator activated receptor gamma0.262
Tgfbr2transforming growth factor, beta receptor II0.242
Apoeapolipoprotein E0.237
Ccne1cyclin E10.225
Smad3MAD homolog 3 (Drosophila)0.195
Mybmyeloblastosis oncogene0.186
Tcf7transcription factor 7, T-cell specific0.182
Socs1suppressor of cytokine signaling 10.169
Fgfr2fibroblast growth factor receptor 20.162
Il6interleukin 60.161
Cdh5cadherin 50.156
Pnpla2patatin-like phospholipase domain containing 20.156
Ccnb2cyclin B20.155
ND6NADH dehydrogenase subunit 60.151
WrnWerner syndrome homolog (human)0.145
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.142
Csf1colony stimulating factor 1 (macrophage)0.136
Hist1h1ahistone cluster 1, H1a0.127
Ccna2cyclin A20.125
Hes1hairy and enhancer of split 1 (Drosophila)0.121
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.121
Slc40a1solute carrier family 40 (iron-regulated transporter), member 10.117
Naspnuclear autoantigenic sperm protein (histone-binding)0.112
Nos3nitric oxide synthase 3, endothelial cell0.112
Cdk6cyclin-dependent kinase 60.111
Adrb3adrenergic receptor, beta 30.111
F10coagulation factor X0.102
Vav3vav 3 oncogene0.098
Cav1caveolin 1, caveolae protein0.097
Ldlrlow density lipoprotein receptor0.096
Uchl1ubiquitin carboxy-terminal hydrolase L10.093
Tal1T-cell acute lymphocytic leukemia 10.083
Acvrl1activin A receptor, type II-like 10.081
Kng1kininogen 10.079
Ccne2cyclin E20.079
Adrb1adrenergic receptor, beta 10.078
Esr1estrogen receptor 1 (alpha)0.078
Orm2orosomucoid 20.077
Ren1renin 1 structural0.077
Stat6signal transducer and activator of transcription 60.076
Atp7aATPase, Cu++ transporting, alpha polypeptide0.076
Ghrgrowth hormone receptor0.075
Il1r1interleukin 1 receptor, type I0.072
Tpm4tropomyosin 40.069
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.068
Foxp3forkhead box P30.068
Orm3orosomucoid 30.066
Tgfbr1transforming growth factor, beta receptor I0.066
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.065
Dll1delta-like 1 (Drosophila)0.064
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.063
Nr3c1nuclear receptor subfamily 3, group C, member 10.063
CrpC-reactive protein, pentraxin-related0.061
Lbplipopolysaccharide binding protein0.061
Cyldcylindromatosis (turban tumor syndrome)0.061
Adam17a disintegrin and metallopeptidase domain 170.060
Lrg1leucine-rich alpha-2-glycoprotein 10.060
Serpina10serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 100.060
Acvr1activin A receptor, type 10.059
Sox2SRY-box containing gene 20.058
Hamphepcidin antimicrobial peptide0.058
Pcnaproliferating cell nuclear antigen0.058
H1histocompatibility 10.057
F9coagulation factor IX0.056
Serpina3mserine (or cysteine) peptidase inhibitor, clade A, member 3M0.056
Agpat21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)0.056
Bdkrb2bradykinin receptor, beta 20.056
Vav2vav 2 oncogene0.056
Tgfb2transforming growth factor, beta 20.055
Ptenphosphatase and tensin homolog0.054
Pax2paired box gene 20.053
Foxf1aforkhead box F1a0.053
Tgfbr3transforming growth factor, beta receptor III0.053
Hdac1histone deacetylase 10.051
Mrapmelanocortin 2 receptor accessory protein0.051
Rararetinoic acid receptor, alpha0.051
Pim1proviral integration site 10.051
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.050
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism