Process View
The network for 'positive regulation of tolerance induction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that activates or increases the frequency, rate, or extent of tolerance induction.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
RT1-EC2 | RT1 class Ib, locus EC2 | 1.000 | |
RT1-CE12 | RT1 class I, locus CE12 | 0.918 | |
RT1-S3 | RT1 class Ib, locus S3 | 0.676 | |
Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.575 | |
Irf7 | interferon regulatory factor 7 | 0.502 | |
LOC100364500 | RT1 class I, locus CE11-like | 0.485 | |
B2m | beta-2 microglobulin | 0.480 | |
Lgals9 | lectin, galactoside-binding, soluble, 9 | 0.445 | |
Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.384 | |
Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.186 | |
Oas1a | 2'-5' oligoadenylate synthetase 1A | 0.167 | |
Met | met proto-oncogene | 0.139 | |
RT1-M3-1 | RT1 class Ib, locus M3, gene 1 | 0.138 | |
Kmo | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.121 | |
Ifi35 | interferon-induced protein 35 | 0.117 | |
Olr837 | olfactory receptor 837 | 0.117 | |
RT1-N3 | RT1 class Ib, locus N3 | 0.110 | |
Sorbs1 | sorbin and SH3 domain containing 1 | 0.104 | |
Olr37 | olfactory receptor 37 | 0.094 | |
Dock8 | dedicator of cytokinesis 8 | 0.090 | |
Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.087 | |
Calcrl | calcitonin receptor-like | 0.086 | |
RT1-CE5 | RT1 class I, locus CE5 | 0.082 | |
Cxcl9 | chemokine (C-X-C motif) ligand 9 | 0.082 | |
Irf1 | interferon regulatory factor 1 | 0.075 | |
RT1-Cl | RT1 class Ib, locus Cl | 0.075 | |
Slco2a1 | solute carrier organic anion transporter family, member 2a1 | 0.074 | |
Capn5 | calpain 5 | 0.071 | |
F9 | coagulation factor IX | 0.068 | |
LOC100365106 | rCG32755-like | 0.067 | |
Foxc2 | forkhead box C2 | 0.056 | |
Rsad2 | radical S-adenosyl methionine domain containing 2 | 0.055 | |
Shc3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.055 | |
Lgals5 | lectin, galactose binding, soluble 5 | 0.052 | |
Cd37 | CD37 molecule | 0.049 | |
Arnt | aryl hydrocarbon receptor nuclear translocator | 0.049 | |
Mx1 | myxovirus (influenza virus) resistance 1 | 0.049 | |
Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.048 | |
Lgals3bp | lectin, galactoside-binding, soluble, 3 binding protein | 0.046 | |
Cyp2c23 | cytochrome P450, family 2, subfamily c, polypeptide 23 | 0.046 | |
Anpep | alanyl (membrane) aminopeptidase | 0.043 | |
Hfe | hemochromatosis | 0.042 | |
RT1-CE16 | RT1 class I, locus CE16 | 0.041 | |
Stat1 | signal transducer and activator of transcription 1 | 0.039 | |
Gbp2 | guanylate binding protein 2 | 0.039 | |
Hnf4a | hepatocyte nuclear factor 4, alpha | 0.038 | |
Clic4 | chloride intracellular channel 4 | 0.037 | |
Trim47 | tripartite motif-containing 47 | 0.036 | |
Sardh | sarcosine dehydrogenase | 0.036 | |
Fcgr3a | Fc fragment of IgG, low affinity IIIa, receptor | 0.036 | |
Entpd1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.036 | |
Cyba | cytochrome b-245, alpha polypeptide | 0.035 | |
Igtp | interferon gamma induced GTPase | 0.034 | |
Tap1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.034 | |
Ccl5 | chemokine (C-C motif) ligand 5 | 0.033 | |
Itga6 | integrin, alpha 6 | 0.033 | |
Adam10 | ADAM metallopeptidase domain 10 | 0.032 | |
LOC100360587 | hypothetical protein LOC100360587 | 0.032 | |
Sod3 | superoxide dismutase 3, extracellular | 0.032 | |
Ppara | peroxisome proliferator activated receptor alpha | 0.031 | |
Otc | ornithine carbamoyltransferase | 0.031 | |
Rbm5 | RNA binding motif protein 5 | 0.030 | |
Bmp6 | bone morphogenetic protein 6 | 0.030 | |
Bst2 | bone marrow stromal cell antigen 2 | 0.029 | |
Man2b1 | mannosidase, alpha, class 2B, member 1 | 0.029 | |
Galr3 | galanin receptor 3 | 0.029 | |
Plbd2 | phospholipase B domain containing 2 | 0.028 | |
Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.027 | |
Ugt1a7c | UDP glucuronosyltransferase 1 family, polypeptide A7C | 0.027 | |
Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.027 | |
Tapbp | TAP binding protein | 0.025 | |
RT1-CE2 | RT1 class I, locus CE2 | 0.024 | |
Elf1 | E74-like factor 1 | 0.024 | |
Cyp2b3 | cytochrome P450, family 2, subfamily b, polypeptide 3 | 0.023 | |
Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.023 | |
C8b | complement component 8, beta polypeptide | 0.023 | |
Rtp4 | receptor (chemosensory) transporter protein 4 | 0.022 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.022 | |
Cyp2f4 | cytochrome P450, family 2, subfamily f, polypeptide 4 | 0.022 | |
Slc22a18 | solute carrier family 22, member 18 | 0.022 | |
Gbp5 | guanylate binding protein 5 | 0.022 | |
Plg | plasminogen | 0.021 | |
Il8ra | interleukin 8 receptor, alpha | 0.021 | |
Dag1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.020 | |
Tnfaip2 | tumor necrosis factor, alpha-induced protein 2 | 0.020 | |
Mgat1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 0.020 | |
Akr1c14 | aldo-keto reductase family 1, member C14 | 0.020 | |
RT1-M6-2 | RT1 class I, locus M6, gene 2 | 0.020 | |
Ocln | occludin | 0.020 | |
Itpkb | inositol 1,4,5-trisphosphate 3-kinase B | 0.020 | |
Cd4 | Cd4 molecule | 0.020 | |
RT1-CE4 | RT1 class I, locus CE4 | 0.020 | |
Itgb5 | integrin, beta 5 | 0.019 | |
Nek9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.019 | |
RT1-Ba | RT1 class II, locus Ba | 0.019 | |
RT1-CE15 | RT1 class I, locus CE15 | 0.018 | |
Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.018 | |
Oasl2 | 2'-5' oligoadenylate synthetase-like 2 | 0.018 | |
Ctsh | cathepsin H | 0.018 | |
Slco2b1 | solute carrier organic anion transporter family, member 2b1 | 0.018 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
B2M | beta-2-microglobulin | 0.995 | |
HLA-C | major histocompatibility complex, class I, C | 0.994 | |
HLA-G | major histocompatibility complex, class I, G | 0.974 | |
HLA-F | major histocompatibility complex, class I, F | 0.910 | |
HLA-A | major histocompatibility complex, class I, A | 0.893 | |
HLA-B | major histocompatibility complex, class I, B | 0.736 | |
HLA-E | major histocompatibility complex, class I, E | 0.694 | |
LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 0.203 | |
LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.114 | |
ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.060 | |
LCK | lymphocyte-specific protein tyrosine kinase | 0.053 | |
PILRA | paired immunoglobin-like type 2 receptor alpha | 0.045 | |
CD247 | CD247 molecule | 0.043 | |
LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 0.042 | |
PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.034 | |
IFITM2 | interferon induced transmembrane protein 2 (1-8D) | 0.027 | |
TAPBP | TAP binding protein (tapasin) | 0.025 | |
PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.023 | |
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.023 | |
CD14 | CD14 molecule | 0.022 | |
LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.019 | |
IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.018 | |
TPP1 | tripeptidyl peptidase I | 0.018 | |
SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.017 | |
HK3 | hexokinase 3 (white cell) | 0.017 | |
PTAFR | platelet-activating factor receptor | 0.016 | |
TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.015 | |
GRN | granulin | 0.015 | |
IFITM3 | interferon induced transmembrane protein 3 (1-8U) | 0.014 | |
PSAP | prosaposin | 0.014 | |
TGFB3 | transforming growth factor, beta 3 | 0.014 | |
ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.013 | |
BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.013 | |
IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.012 | |
IKZF3 | IKAROS family zinc finger 3 (Aiolos) | 0.012 | |
LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 0.012 | |
LILRA3 | leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 | 0.012 | |
SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.011 | |
TREM1 | triggering receptor expressed on myeloid cells 1 | 0.011 | |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.011 | |
FSTL1 | follistatin-like 1 | 0.010 | |
TAPBPL | TAP binding protein-like | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Traf6 | TNF receptor-associated factor 6 | 0.929 | |
Tgfbr1 | transforming growth factor, beta receptor I | 0.733 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.650 | |
Smad4 | MAD homolog 4 (Drosophila) | 0.441 | |
H2-D1 | histocompatibility 2, D region locus 1 | 0.330 | |
Myd88 | myeloid differentiation primary response gene 88 | 0.277 | |
H2-Q7 | histocompatibility 2, Q region locus 7 | 0.251 | |
Shc1 | src homology 2 domain-containing transforming protein C1 | 0.197 | |
Smad6 | MAD homolog 6 (Drosophila) | 0.180 | |
Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.132 | |
Tapbp | TAP binding protein | 0.103 | |
B2m | beta-2 microglobulin | 0.070 | |
Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.055 | |
H2-Q6 | histocompatibility 2, Q region locus 6 | 0.048 | |
Smad7 | MAD homolog 7 (Drosophila) | 0.048 | |
H2-K1 | histocompatibility 2, K1, K region | 0.045 | |
Eng | endoglin | 0.043 | |
Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.041 | |
Cd3d | CD3 antigen, delta polypeptide | 0.038 | |
Ece1 | endothelin converting enzyme 1 | 0.035 | |
Efemp2 | epidermal growth factor-containing fibulin-like extracellular matrix protein 2 | 0.035 | |
Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.034 | |
Rnf11 | ring finger protein 11 | 0.031 | |
Smad1 | MAD homolog 1 (Drosophila) | 0.031 | |
Irak4 | interleukin-1 receptor-associated kinase 4 | 0.031 | |
Cyld | cylindromatosis (turban tumor syndrome) | 0.030 | |
Dvl1 | dishevelled, dsh homolog 1 (Drosophila) | 0.030 | |
Prkg1 | protein kinase, cGMP-dependent, type I | 0.028 | |
Atp7a | ATPase, Cu++ transporting, alpha polypeptide | 0.027 | |
Kiss1 | KiSS-1 metastasis-suppressor | 0.025 | |
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.025 | |
Grb2 | growth factor receptor bound protein 2 | 0.022 | |
H2-Q8 | histocompatibility 2, Q region locus 8 | 0.021 | |
Foxp1 | forkhead box P1 | 0.020 | |
Acvr1 | activin A receptor, type 1 | 0.020 | |
Cdh5 | cadherin 5 | 0.020 | |
Vegfa | vascular endothelial growth factor A | 0.019 | |
Pthlh | parathyroid hormone-like peptide | 0.019 | |
Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.018 | |
Stat3 | signal transducer and activator of transcription 3 | 0.018 | |
Cd3g | CD3 antigen, gamma polypeptide | 0.017 | |
Kif19a | kinesin family member 19A | 0.016 | |
Tax1bp1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.015 | |
Grb10 | growth factor receptor bound protein 10 | 0.015 | |
Bptf | bromodomain PHD finger transcription factor | 0.014 | |
Sh2d2a | SH2 domain protein 2A | 0.014 | |
Smurf1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.013 | |
Hipk3 | homeodomain interacting protein kinase 3 | 0.013 | |
Tmem64 | transmembrane protein 64 | 0.013 | |
Mkl2 | MKL/myocardin-like 2 | 0.012 | |
Sox9 | SRY-box containing gene 9 | 0.012 | |
Agtr1a | angiotensin II receptor, type 1a | 0.012 | |
Tlr4 | toll-like receptor 4 | 0.011 | |
Ticam1 | toll-like receptor adaptor molecule 1 | 0.011 | |
Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.011 | |
Cpd | carboxypeptidase D | 0.011 | |
Cd8b1 | CD8 antigen, beta chain 1 | 0.011 | |
Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.011 | |
Ednra | endothelin receptor type A | 0.010 | |
Cd6 | CD6 antigen | 0.010 | |
Erbb2ip | Erbb2 interacting protein | 0.010 | |
Cbl | Casitas B-lineage lymphoma | 0.010 | |
Kif3a | kinesin family member 3A | 0.010 |